The E-Class PPR Protein MEF3 of Arabidopsis
... proteins in the mapped genomic window into Ler protoplasts shows differential effects. Sequence analysis of the atp4 cDNA shows that gene At1g06140 strongly increases the level of RNA editing at the target site atp4-89 in the transfected protoplasts. Gene At1g06580 also alters the editing level in c ...
... proteins in the mapped genomic window into Ler protoplasts shows differential effects. Sequence analysis of the atp4 cDNA shows that gene At1g06140 strongly increases the level of RNA editing at the target site atp4-89 in the transfected protoplasts. Gene At1g06580 also alters the editing level in c ...
Small Nucleolar RNA
... • Loss of either the paternal or maternal copy of this region leads to two neurological disorders: Prader-Willi or Angelman ...
... • Loss of either the paternal or maternal copy of this region leads to two neurological disorders: Prader-Willi or Angelman ...
Messenger RNA reprogramming by spliceosome-mediated
... domains provide PTMs with the cis elements required for spliceosome recognition and splicing. A PTM with a 5′ splice site domain can trans-splice to a 3′ splice site in the target pre-mRNA (ii in Figure 5); a PTM with a 3′ splice site domain can trans-splice to a 5′ splice site in the target (iii); ...
... domains provide PTMs with the cis elements required for spliceosome recognition and splicing. A PTM with a 5′ splice site domain can trans-splice to a 3′ splice site in the target pre-mRNA (ii in Figure 5); a PTM with a 3′ splice site domain can trans-splice to a 5′ splice site in the target (iii); ...
Coexpression of Linked Genes in Mammalian
... of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be highly organized. However, the high plasticity of yeast gene order revealed from a comparison of 11 species (Fischer et al. 2006) argues against this view. In addition, it is we ...
... of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be highly organized. However, the high plasticity of yeast gene order revealed from a comparison of 11 species (Fischer et al. 2006) argues against this view. In addition, it is we ...
Factors Affecting synonymous codon Usage Bias in chloroplast
... plant nuclear genes and in chloroplasts.32 Chloroplasts differ from the nuclear genome of higher plants in that they encode only 30 tRNA species. Since chloroplasts have restricted their tRNA genes, the use of preferred codons by chloroplast encoded proteins appears more extreme. However, a positive ...
... plant nuclear genes and in chloroplasts.32 Chloroplasts differ from the nuclear genome of higher plants in that they encode only 30 tRNA species. Since chloroplasts have restricted their tRNA genes, the use of preferred codons by chloroplast encoded proteins appears more extreme. However, a positive ...
Spatially ordered transcription of regulatory DNA in
... germ band is extended both ectoderm and mesoderm show expression (Fig. 4C,E). Later, the signal is particularly strong in the ventral nerve cord, although the ectoderm is also labelled (Fig. 4D,F). We can attribute no function to these transcripts, as chromosome breaks in the iab region have no appa ...
... germ band is extended both ectoderm and mesoderm show expression (Fig. 4C,E). Later, the signal is particularly strong in the ventral nerve cord, although the ectoderm is also labelled (Fig. 4D,F). We can attribute no function to these transcripts, as chromosome breaks in the iab region have no appa ...
transposon
... is given the prefix IS, followed by a number that identifies the type. The IS elements are normal constituents of bacterial chromosomes and plasmids. To describe an insertion into a particular site, a double colon is used; so λ::IS1 describes an IS1 element inserted into phage lambda. The IS ele ...
... is given the prefix IS, followed by a number that identifies the type. The IS elements are normal constituents of bacterial chromosomes and plasmids. To describe an insertion into a particular site, a double colon is used; so λ::IS1 describes an IS1 element inserted into phage lambda. The IS ele ...
Genome Biology - Institute for Applied Ecology
... chickens a female specific non-coding RNA is expressed from the MHM (male hypermethylated) locus and accumulates near its transcription site on the Z chromosome [22]. In ZZ males, the DNA at the MHM locus remains hypermethylated and untranscribed [22]. In addition, histone H4 at lysine residue 16 is ...
... chickens a female specific non-coding RNA is expressed from the MHM (male hypermethylated) locus and accumulates near its transcription site on the Z chromosome [22]. In ZZ males, the DNA at the MHM locus remains hypermethylated and untranscribed [22]. In addition, histone H4 at lysine residue 16 is ...
Structural maintenance of chromosome complexes and bone
... genes and their associated molecular pathways are central for the growth and development of healthy bones. The correct expression of genes depends on both cis- and trans-regulatory elements. Of these, the elusive role of chromatin ultrastructure is just beginning to become appreciated. Changes in th ...
... genes and their associated molecular pathways are central for the growth and development of healthy bones. The correct expression of genes depends on both cis- and trans-regulatory elements. Of these, the elusive role of chromatin ultrastructure is just beginning to become appreciated. Changes in th ...
Alu
... Place K points into the space represented by the objects that are being clustered. These points represent initial group centroids. Assign each object to the group that has the closest centroid. When all objects have been assigned, recalculate the positions of the K centroids. Repeat Steps 2 an ...
... Place K points into the space represented by the objects that are being clustered. These points represent initial group centroids. Assign each object to the group that has the closest centroid. When all objects have been assigned, recalculate the positions of the K centroids. Repeat Steps 2 an ...
Letter Gene Survival and Death on the Human Y
... with evidence of homologous Y sequence, and only two exons were recovered for the remaining two genes. Because these 31 genes do not appear to be conserved from the ancestral X chromosome, are nearly all part of multigene families, and only one exon was recovered on the Y, the similarity search like ...
... with evidence of homologous Y sequence, and only two exons were recovered for the remaining two genes. Because these 31 genes do not appear to be conserved from the ancestral X chromosome, are nearly all part of multigene families, and only one exon was recovered on the Y, the similarity search like ...
A method for finding molecular signatures from gene expression data
... Provide insight into biological mechanisms and processes and have potential diagnostic use. However, searching for molecular signatures often done using a very diverse and ad-hoc methodology. ...
... Provide insight into biological mechanisms and processes and have potential diagnostic use. However, searching for molecular signatures often done using a very diverse and ad-hoc methodology. ...
A series of promoters for constitutive expression of heterologous
... (Matsuyama et al., 2004) and its promoter derivatives. These plasmids were then integrated into the leu1 locus of AM2, as was the case for GFP. We carried out β-galactosidase assays using integrants grown in the media that were also used to monitor the GFP expression. Although the signal range was d ...
... (Matsuyama et al., 2004) and its promoter derivatives. These plasmids were then integrated into the leu1 locus of AM2, as was the case for GFP. We carried out β-galactosidase assays using integrants grown in the media that were also used to monitor the GFP expression. Although the signal range was d ...
Solid Tumour Section Mesothelioma: t(14;22)(q32;q12) in mesothelioma Atlas of Genetics and Cytogenetics
... exon 8 of EWSR1 (nucleotide 1139 accession number NM_013986 version 3; former exon 7 in sequence with accession number X66899) is fused to exon 2 of YY1 (nucleotide 1160 accession number NM_003403 version 3). The putative EWSR1-YY1 protein would contain the transactivation domain of EWSR1 and the DN ...
... exon 8 of EWSR1 (nucleotide 1139 accession number NM_013986 version 3; former exon 7 in sequence with accession number X66899) is fused to exon 2 of YY1 (nucleotide 1160 accession number NM_003403 version 3). The putative EWSR1-YY1 protein would contain the transactivation domain of EWSR1 and the DN ...
Identification of lineage-specific zygotic transcripts in early
... mesendodermal precursor, EMS, in the 4-cell stage embryo. When EMS divides, it gives rise to a mesoderm-restricted precursor, MS, and an endoderm-restricted precursor, E. To systematically identify genes that function as key regulators of MS and/or E-derived tissues, we identified, by microarray ana ...
... mesendodermal precursor, EMS, in the 4-cell stage embryo. When EMS divides, it gives rise to a mesoderm-restricted precursor, MS, and an endoderm-restricted precursor, E. To systematically identify genes that function as key regulators of MS and/or E-derived tissues, we identified, by microarray ana ...
PDF
... normal, i.e. 5-7 equal-length tentacles arranged radially around the hypostome. Occasionally 3 or 4 tentacles were shorter than normal but usually these increased in length to fit the normal pattern. None of these compounds caused any alterations of polarity. At non-toxic concentrations reconstituti ...
... normal, i.e. 5-7 equal-length tentacles arranged radially around the hypostome. Occasionally 3 or 4 tentacles were shorter than normal but usually these increased in length to fit the normal pattern. None of these compounds caused any alterations of polarity. At non-toxic concentrations reconstituti ...
Complete Sequence of the Mitochondrial DNA of
... (Boore and Brown 1994a), and the land snail A. coerulea (Hatzoglou, George, and Lecanidou 1995). The tRNA genes were identified by their potential to form their characteristic secondary structures. Nucleotide and amino acid sequences of the protein genes were aligned with their counterparts of other ...
... (Boore and Brown 1994a), and the land snail A. coerulea (Hatzoglou, George, and Lecanidou 1995). The tRNA genes were identified by their potential to form their characteristic secondary structures. Nucleotide and amino acid sequences of the protein genes were aligned with their counterparts of other ...
Cotranscriptional coupling of splicing factor recruitment and
... DNA supercoiling that occurs during transcription27,28. Over 30 sites treatment. We verified by reverse-transcription (RT)-PCR that arsenite of topoisomerase I activity are distributed throughout the FOS gene treatment did not impair splicing of MYC pre-mRNA (data not and have been mapped with campt ...
... DNA supercoiling that occurs during transcription27,28. Over 30 sites treatment. We verified by reverse-transcription (RT)-PCR that arsenite of topoisomerase I activity are distributed throughout the FOS gene treatment did not impair splicing of MYC pre-mRNA (data not and have been mapped with campt ...
Mitonuclear linkage disequilibrium in human populations
... SNP genotypes from 1041 geographically and genetically diverse individuals revealed that mitonuclear LD is prevalent throughout the human genome. The vast majority (89%) of nuclear SNPs exhibited a significantly non-random association with mitochondrial haplogroups at an FDR threshold of 0.05, and g ...
... SNP genotypes from 1041 geographically and genetically diverse individuals revealed that mitonuclear LD is prevalent throughout the human genome. The vast majority (89%) of nuclear SNPs exhibited a significantly non-random association with mitochondrial haplogroups at an FDR threshold of 0.05, and g ...
here - Genomes Unzipped
... genomes have been sequenced at low coverage [2], and identified 10,210 sites of mismatches between an individual’s mRNA and DNA sequences (RDD sites, for RNA-DNA difference). RDD sites included all possible combinations of sequence mismatches, and the authors validated a subset of these mismatches b ...
... genomes have been sequenced at low coverage [2], and identified 10,210 sites of mismatches between an individual’s mRNA and DNA sequences (RDD sites, for RNA-DNA difference). RDD sites included all possible combinations of sequence mismatches, and the authors validated a subset of these mismatches b ...
An In Silico Investigation Into the Discovery of Novel Cis
... PAX genes based not only on sequence but on genomic organization. Genes within a given class have intron/exon boundaries and encoding regions in common. Pax3 and Pax7 are closely related paired box family members expressed during early neural and myogenic development and have been implicated in the ...
... PAX genes based not only on sequence but on genomic organization. Genes within a given class have intron/exon boundaries and encoding regions in common. Pax3 and Pax7 are closely related paired box family members expressed during early neural and myogenic development and have been implicated in the ...
Development of novel computational tools based on
... of life. The exchange of genetic material was found to have occurred in different domains of life: Archaea, Bacteria, and Eukarya (Choi and Kim, 2007). Horizontal gene transfer, defined as a mechanism that promotes the transfer of foreign genomic segments between lineages was found to be relatively ...
... of life. The exchange of genetic material was found to have occurred in different domains of life: Archaea, Bacteria, and Eukarya (Choi and Kim, 2007). Horizontal gene transfer, defined as a mechanism that promotes the transfer of foreign genomic segments between lineages was found to be relatively ...
NUCLEIC ACID CATALYSTS: COMPARING THE MECHANISMS OF
... site-specific cleavage ability of the DNAzyme has potential medicinal applications. DNA and RNA enzymes can be used to target and cleave specific strands of RNA that have negative effects, such as viral RNA (6). Additionally, a better understanding of nucleic acids and proteins can help scientists u ...
... site-specific cleavage ability of the DNAzyme has potential medicinal applications. DNA and RNA enzymes can be used to target and cleave specific strands of RNA that have negative effects, such as viral RNA (6). Additionally, a better understanding of nucleic acids and proteins can help scientists u ...
Whole-transcriptome RNAseq analysis from minute amount of total
... alternative splice isoforms and direct measurement of transcript abundance (3). These technologies are greatly accelerating our understanding of the complexity of gene expression, regulation and pathways for mammalian cells. Currently, HT-sequencing technologies have been used for whole-transcriptom ...
... alternative splice isoforms and direct measurement of transcript abundance (3). These technologies are greatly accelerating our understanding of the complexity of gene expression, regulation and pathways for mammalian cells. Currently, HT-sequencing technologies have been used for whole-transcriptom ...