Extrapolation to the whole human genome
... Main non-processed pseudogene populations We examined the non-processed pseudogene populations for chromosomes 21 and 22 for their prevalent functional classes and compared them to the classes for genes predicted using GenomeScan (Yeh et al., 2001). The total number of InterPro motif assignments and ...
... Main non-processed pseudogene populations We examined the non-processed pseudogene populations for chromosomes 21 and 22 for their prevalent functional classes and compared them to the classes for genes predicted using GenomeScan (Yeh et al., 2001). The total number of InterPro motif assignments and ...
Sex Chromosome Dosage Effects On Gene Expression In
... to test the original model and were able to confirm reduction in expression with greater X-chromosome dosage (ARAF, NGFRAP1, CXorf57, TIMP1), and Ychromosome dosage effects upon expression of X-linked genes (NGFRAP1, CXorf57, PIM2, IL2RG, MORF4L2). Our findings update the canonical Four Class Model ...
... to test the original model and were able to confirm reduction in expression with greater X-chromosome dosage (ARAF, NGFRAP1, CXorf57, TIMP1), and Ychromosome dosage effects upon expression of X-linked genes (NGFRAP1, CXorf57, PIM2, IL2RG, MORF4L2). Our findings update the canonical Four Class Model ...
PDF
... to test the original model and were able to confirm reduction in expression with greater X-chromosome dosage (ARAF, NGFRAP1, CXorf57, TIMP1), and Ychromosome dosage effects upon expression of X-linked genes (NGFRAP1, CXorf57, PIM2, IL2RG, MORF4L2). Our findings update the canonical Four Class Model ...
... to test the original model and were able to confirm reduction in expression with greater X-chromosome dosage (ARAF, NGFRAP1, CXorf57, TIMP1), and Ychromosome dosage effects upon expression of X-linked genes (NGFRAP1, CXorf57, PIM2, IL2RG, MORF4L2). Our findings update the canonical Four Class Model ...
Molecular Biology of Transcription and RNA Processing
... translation. Messenger RNA is the only form of RNA that undergoes translation. Transcription of mRNA and posttranscriptional processing of mRNA are principal areas of focus in this chapter. Functional RNAs perform a variety of specialized roles in the cell. The functional RNAs carry out their activ ...
... translation. Messenger RNA is the only form of RNA that undergoes translation. Transcription of mRNA and posttranscriptional processing of mRNA are principal areas of focus in this chapter. Functional RNAs perform a variety of specialized roles in the cell. The functional RNAs carry out their activ ...
Application of Bruchin B to pea pods results in
... are much smaller than those seen on Np/Np pods and much of their mass results from cell enlargement rather than cell division; however, the minimum dose required to elicit a response on pods of either genotype appears to be about the same (Doss et al., 2000). Interestingly, the Np gene was described ...
... are much smaller than those seen on Np/Np pods and much of their mass results from cell enlargement rather than cell division; however, the minimum dose required to elicit a response on pods of either genotype appears to be about the same (Doss et al., 2000). Interestingly, the Np gene was described ...
Genomic approaches for the understanding of aging
... Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan 336-745, Korea ...
... Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan 336-745, Korea ...
A defense-offense multi-layered regulatory switch in a pathogenic
... and represses the offensive genes (26–28); (ii) the regulatory RNA, RNAIII, which is activated when cell density increases, and simultaneously represses post-transcriptionally both rot (28) and the defensive genes while activating the translation of the exotoxin hla (29). The agr system, which sense ...
... and represses the offensive genes (26–28); (ii) the regulatory RNA, RNAIII, which is activated when cell density increases, and simultaneously represses post-transcriptionally both rot (28) and the defensive genes while activating the translation of the exotoxin hla (29). The agr system, which sense ...
Polyamines and other charged amines bind to RNA by hydrogen
... DNA in which phosphate groups interact with each positively charged amino group, the tetramethylene portion of the polyamine bridges the narrow (minor) groove of the helix between the two strands and the trimethylene portion bridges adjacent phosphate groups. Gabbay and co-workers 1 0 > n proposed t ...
... DNA in which phosphate groups interact with each positively charged amino group, the tetramethylene portion of the polyamine bridges the narrow (minor) groove of the helix between the two strands and the trimethylene portion bridges adjacent phosphate groups. Gabbay and co-workers 1 0 > n proposed t ...
Comparison of Identified TSS Locations to Other
... available set of ESTs, and may change with the inclusion of additional 5’ capped data. The two main sources of library bias that can affect the determination of the condition-specificity of the TSSs by applying Shannon entropy to the ESTs are library normalization and library size. While we recogniz ...
... available set of ESTs, and may change with the inclusion of additional 5’ capped data. The two main sources of library bias that can affect the determination of the condition-specificity of the TSSs by applying Shannon entropy to the ESTs are library normalization and library size. While we recogniz ...
Nucleic Acids: RNA and chemistry
... codes for a protein SO there needs to be a process for getting rid of the unwanted bases in the mRNA: that’s what splicing is! ...
... codes for a protein SO there needs to be a process for getting rid of the unwanted bases in the mRNA: that’s what splicing is! ...
ucsc genome research primer - Center for Biomolecular Science
... The human genome comprises a sequence of approximately 3 billion component parts, called nucleotides, which are organized into DNA molecules—the double helix. The nucleotides, which serve as the alphabet for the language of life, are represented by just four letters: A, C, G, and T, corresponding to ...
... The human genome comprises a sequence of approximately 3 billion component parts, called nucleotides, which are organized into DNA molecules—the double helix. The nucleotides, which serve as the alphabet for the language of life, are represented by just four letters: A, C, G, and T, corresponding to ...
Combined expression patterns of QTL
... knockdown tube connected to a water jacket attached to a single circulating bath. No anesthesia treatment was used to manipulate experimental flies. In addition to pilot studies by us, comparisons of independent measurements from previous studies (Norry et al., 2004, 2008), indicated that KRHT at 36– ...
... knockdown tube connected to a water jacket attached to a single circulating bath. No anesthesia treatment was used to manipulate experimental flies. In addition to pilot studies by us, comparisons of independent measurements from previous studies (Norry et al., 2004, 2008), indicated that KRHT at 36– ...
Life 9e - Garvness
... Bloom’s Category: 1. Remembering 4. Which of the following are model organisms used in biological research? a. Pea plants b. Fruit flies c. E. coli d. Bread mold e. All of the above Answer: e Textbook Reference: 14.1 What Is the Evidence that Genes Code for Proteins? Page: 292 Bloom’s Category: 1. R ...
... Bloom’s Category: 1. Remembering 4. Which of the following are model organisms used in biological research? a. Pea plants b. Fruit flies c. E. coli d. Bread mold e. All of the above Answer: e Textbook Reference: 14.1 What Is the Evidence that Genes Code for Proteins? Page: 292 Bloom’s Category: 1. R ...
PDF - Blood Journal
... Surprisingly, the genes have split onto separate chromosomes in the pufferfish, as demonstrated by DNA–fluorescence in situ hybridization (FISH) analysis. Sequence analysis of the cosmid containing the -globin gene reveals close linkage with 2 ␣-globin genes, ␣3 and ␣4; we refer to this locus as th ...
... Surprisingly, the genes have split onto separate chromosomes in the pufferfish, as demonstrated by DNA–fluorescence in situ hybridization (FISH) analysis. Sequence analysis of the cosmid containing the -globin gene reveals close linkage with 2 ␣-globin genes, ␣3 and ␣4; we refer to this locus as th ...
PDF
... Based on ab initio and homology-based (including transcriptomic sequences generated by RNA-Seq) approaches, we predicted 43 703 protein-coding genes with a mean coding sequence length of 990 bp and an average number of 4.7 exons per gene (Table 1). Of the 43 703 predicted genes, 41 097 (94.0%) were ...
... Based on ab initio and homology-based (including transcriptomic sequences generated by RNA-Seq) approaches, we predicted 43 703 protein-coding genes with a mean coding sequence length of 990 bp and an average number of 4.7 exons per gene (Table 1). Of the 43 703 predicted genes, 41 097 (94.0%) were ...
The Comparison of Transcriptomes Undergoing Waterlogging at the
... The data of GH01 was analysed with the recently published transcriptome dataset of the tolerant variety ZS9 under the same treatment (Zou et al. 2013c; Zou et al. 2014a). A total of 2994 overlapping genes between GH01 (4857) and ZS9 (4432) were identified (Appendix B). A comprehensive analysis of th ...
... The data of GH01 was analysed with the recently published transcriptome dataset of the tolerant variety ZS9 under the same treatment (Zou et al. 2013c; Zou et al. 2014a). A total of 2994 overlapping genes between GH01 (4857) and ZS9 (4432) were identified (Appendix B). A comprehensive analysis of th ...
Maternal and paternal genomes contribute equally to the
... form of imprinting in the Arabidopsis embryo. Genome-wide approaches similar to ours but looking much later after fertilization greatly expanded the list of genes with parent-of-origin-specific expression in the endosperm but did not identify such genes in embryos23,24. Thus, the imprinting-like phe ...
... form of imprinting in the Arabidopsis embryo. Genome-wide approaches similar to ours but looking much later after fertilization greatly expanded the list of genes with parent-of-origin-specific expression in the endosperm but did not identify such genes in embryos23,24. Thus, the imprinting-like phe ...
Interactions of Mitochondrial and Nuclear Genes
... because a restorer locus may affect the transcript profile of not only a CMS-associated gene but also that of a normal gene. Thus, a gene could be wrongly implicated in CMS if it happens to be affected by a restorer allele. The strongest evidence comes from a combination of altered expression in res ...
... because a restorer locus may affect the transcript profile of not only a CMS-associated gene but also that of a normal gene. Thus, a gene could be wrongly implicated in CMS if it happens to be affected by a restorer allele. The strongest evidence comes from a combination of altered expression in res ...
View PDF - Genetics
... transferred to the nuclear genome are trafficked back into the plastid (Gould et al. 2008), where they interact closely with proteins encoded by genes remaining in the plastid genome. These interacting proteins are key not only to photosynthesis, but also to transcription, translation and critical ...
... transferred to the nuclear genome are trafficked back into the plastid (Gould et al. 2008), where they interact closely with proteins encoded by genes remaining in the plastid genome. These interacting proteins are key not only to photosynthesis, but also to transcription, translation and critical ...
E.coli
... Codon preference and tRNA : Ikemura, 1985; Bennetzen and Hall, 1982; Bulmer, 1987; Gouy and Gautier, 1982. tRNA and elongation rate : Varenne et al., 1984. High expression and codon preference : Grantham et al., 1980; Wada et al., 1990; Sharp and Li, 1987; Sharp et al., 1986; Médigue et al., 1991; S ...
... Codon preference and tRNA : Ikemura, 1985; Bennetzen and Hall, 1982; Bulmer, 1987; Gouy and Gautier, 1982. tRNA and elongation rate : Varenne et al., 1984. High expression and codon preference : Grantham et al., 1980; Wada et al., 1990; Sharp and Li, 1987; Sharp et al., 1986; Médigue et al., 1991; S ...
Chromatin: A sticky silence
... Finally, the variegation caused by multiple tandem repeats of a mini-white transgene and that caused by multiple tandem repeats of the brown gene are both enhanced by their proximity to heterochromatin [16,17]. As different types of heterochromatin-related repression are dependent upon nuclear local ...
... Finally, the variegation caused by multiple tandem repeats of a mini-white transgene and that caused by multiple tandem repeats of the brown gene are both enhanced by their proximity to heterochromatin [16,17]. As different types of heterochromatin-related repression are dependent upon nuclear local ...
Genome-wide histone modification patterns in
... bioRxiv preprint first posted online Feb. 15, 2016; doi: http://dx.doi.org/10.1101/039776. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
... bioRxiv preprint first posted online Feb. 15, 2016; doi: http://dx.doi.org/10.1101/039776. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
Nonconventional Initiation Complex Assembly by STAT and NF
... A. Macrophages with IFN-I + hkL -> increase of histone acetylation at both the proximal and distal promoter locations B. Treatment with IFN-I -> increase of H4 acetylation at the distal IFN response region C. hkL treatment -> increase in H4 acetylation at the proximal NF-κB element ISGF3 and NF-κB ...
... A. Macrophages with IFN-I + hkL -> increase of histone acetylation at both the proximal and distal promoter locations B. Treatment with IFN-I -> increase of H4 acetylation at the distal IFN response region C. hkL treatment -> increase in H4 acetylation at the proximal NF-κB element ISGF3 and NF-κB ...
08.seg_dup_els - NYU Computer Science
... structure, distribution, and fluctuating copy-numbers [Zhou & Mishra (2004), Thomas et al (2004)]. At multiple scales, these genomes have evolved many complex patterns of duplications, among which large segmental duplications (SDs) appear to be one of the most mysterious, both in their origin as wel ...
... structure, distribution, and fluctuating copy-numbers [Zhou & Mishra (2004), Thomas et al (2004)]. At multiple scales, these genomes have evolved many complex patterns of duplications, among which large segmental duplications (SDs) appear to be one of the most mysterious, both in their origin as wel ...
Prof. Kamakaka`s Lecture 16 Notes
... In addition to negative regulation by the lac repressor, the lac operon also required positive regulation. That is, a factor was needed for specific activation of the operon. The specific activator was called CAP ( Catabolic activator protein) produced by the gene crp (not part of the lac operon). C ...
... In addition to negative regulation by the lac repressor, the lac operon also required positive regulation. That is, a factor was needed for specific activation of the operon. The specific activator was called CAP ( Catabolic activator protein) produced by the gene crp (not part of the lac operon). C ...