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A Novel Chimeric Low-Molecular-Weight Glutenin
A Novel Chimeric Low-Molecular-Weight Glutenin

... Phylogenetic analysis among LMW-GS and other storage protein genes: The 27 gene sequences coding for LMW-GS, gliadins, and hordeins from GenBank were used to construct a homology tree, including 3 LMW-s-type, 12 LMW-m-type, and 5 LMW-i-type glutenin genes as well as 4 gliadins and 3 hordein genes fr ...
View PDF
View PDF

... of eutherians and marsupials 180 MYA, but before the eutherian radiation 105 MYA. Thus, the PWS–AS domain was constructed relatively recently from non-imprinted components acquired from all over the genome, including protein-coding genes that were translocated or retroposed, snoRNAs and elements tha ...
Genome Databases and Open Access Resources
Genome Databases and Open Access Resources

... Mouse assembly UniGene Transcript ...
Genome-wide expression analysis of cultured
Genome-wide expression analysis of cultured

... which could be expected for this chromosome, on the microarray. Among the classes of genes that best discriminated the trisomy 21 and normal karyotype, we found genes that are also implicated in Alzheimer disease and genes that are associated with ubiquitination and proteosomal degradation. Finally, ...
Diapositive 1 - Institut Pasteur
Diapositive 1 - Institut Pasteur

... Analyses of the genetic material of different species help understanding the similarity and differences between genomes, their evolution and the evolution of their genes. •Intra-genomic comparisons help understanding the degree of duplication (genome regions; genes) and genes organization,... •Inter ...
Lecture 8
Lecture 8

... Identifying orthologous and paralogous genes * Use genome similarity matrix to distinguish between paralogs and orthologs * remember: homologs are genes that have a common ancestor, orthologs arise as homologs evolve in sisterspecies; paralogs arise from duplication and subsequent specialisation * R ...
Alu Human Polymorphism
Alu Human Polymorphism

... Alu elements • Alu has the necessary sequences to be transcribed by RNA Pol III • The LINE (Long INterspersed Element) L1 supplies the reverse transcriptase needed for Alu to jump – L1 is a defective retrovirus – It nicks the DNA close to the sequence AATTTT – The AAAA of Alu transcript binds to th ...
Chapter 7
Chapter 7

... • Unlike the genes of a prokaryotic operon, each of the coordinately controlled eukaryotic genes has a promoter and control elements • These genes can be scattered over different chromosomes, but each has the same combination of control elements • Copies of the activators recognize specific control ...
Globin gene family
Globin gene family

... • Many eukaryotic genes are present in one copy per haploid set of chromosomes • The rest of the genome occurs in multigene families, collections of identical or very similar ...
Prediction of Effective genome size in metagenomics samples
Prediction of Effective genome size in metagenomics samples

... Expect genome size increases proportionally to the inverse marker gene density 1/x at any given length L: EGS = c(L)/x, where c(L) is a readlength dependent calibration factor Based on manual comparison of a variety of possible functional forms, c(L) is well approximated by a power law, c(L) = a + b ...
Transvection, nuclear structure, and chromatin proteins.
Transvection, nuclear structure, and chromatin proteins.

... For instance, the evidence for nuclear compartmentalization (for example, see Carter et al., 1991; Leonhardt et al., 1992 and references within; reviewed by Manuelidis, 1990; Jackson, 1991) and the restriction of transcripts to nuclear '~racks" (Xing and Lawrence, 1991) lend plausibility to a propos ...
GIN Transposons: Genetic Elements Linking Retrotransposons and
GIN Transposons: Genetic Elements Linking Retrotransposons and

... built including them and also sequences from Mdg1 retrotransposons, which were to be used as outgroups. The results are shown in figure 1, and the aligned sequences can be found in supplementary file 2 (Supplementary Material online). The detailed analysis of these new sequences totally changes our ...
Plant and animal microRNAs: similarities and differences
Plant and animal microRNAs: similarities and differences

... miRNAs posttranscriptionally regulate gene expression through interactions with their target mRNAs, and these targets are often genes involved with regulating key developmental events. Despite these similarities, plant and animal miRNAs exert their control in fundamentally different ways. Generally, ...
A haploid-specific transcriptional response to
A haploid-specific transcriptional response to

... Gamma irradiation generates various types of DNA damage, including double-strand breaks (DSBs). A single unre- 55 paired DSB is deleterious for cells, as it may lead to genetic instability and the loss of chromosome fragments. Such damage may occur anywhere in the genome and may have a major effect ...
1 Title: Evidence for large domains of similarly expressed genes in
1 Title: Evidence for large domains of similarly expressed genes in

... restricted to specific target genes. Several examples of insulators, sequences that prevent neighboring modules from affecting transcription have been identified (reviewed in [2]). These insulators seem to function, not by deactivating cis-modules, but by preventing their influence from being propag ...
PDF - Blood Journal
PDF - Blood Journal

... example, Xist, a lncRNA that mediates X-chromosome inactivation, was discovered in 1991.6 This lncRNA and a handful of others were considered to be relatively infrequent until large-scale transcriptome sequencing identified thousands more.2 Now, candidate lncRNAs are recognized by computational algor ...
Nat. Struct. Biol. 8, 192-194.
Nat. Struct. Biol. 8, 192-194.

... The expression of eukaryotic genes in specific tissues and at particular times of development is determined by regulatory sequences called enhancers and silencers. Enhancers bind transcription factors, which then help initiate transcription of the RNA at the promoter. Enhancers accomplish this indep ...
Looping versus linking: toward a model for long
Looping versus linking: toward a model for long

... Finally, it is highly improbable that the DNA content of a cell could be stored in the nucleus if all of the active chromatin domains were to decondense to a 10-nm fiber, when this structure accomplishes only a sevenfold compaction of the DNA. Thus, the structure of an open or active domain consists ...
serious asthma should focus on the possible confounding role
serious asthma should focus on the possible confounding role

... details about genes and gene expression patterns, and how they relate to the development and/or establishment of complex diseases. The impact of TEs on phenotype (variation) and disease are depicted in figure 1. With the advent of next generation sequencing and rapid genome and transcriptome analyse ...
File
File

... d) Some act indirectly by affecting chromatin structure. e) Interaction of specific transcription factors and RNA polymerase II with a promoter leads to a low rate of initiation and production of a few RNA transcripts. © 2014 Pearson Education, Inc. ...
Monday March 10th in-class “assignment”: studying SRS and BWS
Monday March 10th in-class “assignment”: studying SRS and BWS

... ICR2, and CDKN1C. The duplicated ICR2 when inherited maternally is also methylated causing Kcnq1ot1 is not transcribed maternally. However since CDKN1C is doubled, and not repressed in cis by Kcnq1ot1, more CDKN1C protein is present within the cell. CDKN1C repressed growth of the cell, leading to th ...
PartFourAnswers.doc
PartFourAnswers.doc

... where the expression of all thegenes except cI are repressed. Therepressor, or CI protein, will bind to the leftward and rightward operators ofto prevent transcription from PL and PR, hence blocking the expression of the genes required for lytic infection. Bacteria that are lysogenic for ...
zChap12_140901 - Online Open Genetics
zChap12_140901 - Online Open Genetics

... The three-spined stickleback (Figure 12.11) provides an example of natural selection of a mutation in a cis-regulatory element. This fish occurs in two forms: (1) populations that inhabit deep, open water and have a spiny pelvic fin that deters larger predator fish from feeding on them; (2) populati ...
Characterization of Two Rice MADS Box Genes That Control
Characterization of Two Rice MADS Box Genes That Control

... Plants contain a variety of the MADS box genes that encode regulatory proteins and play important roles in both the formation of flower meristem and the determination of floral organ identity. We have characterized two flower-specific cDNAs from rice, designated OsMADS7 and OsMADS8. The cDNAs displa ...
MS Word document - Sequence Ontology
MS Word document - Sequence Ontology

... Mutations causing premature stop. Is this a gene with a mutation or a pseudogene? How do you prove something is a pseudogene. There are lots of permutations to test. Should a pseudogene have to same parts as a gene can have? We may want to annotate its exons. Is a pseudogene a gene? What other types ...
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Short interspersed nuclear elements (SINEs)

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