Genome-wide RNAi Robert Barstead
... to examine systematically all C. elegans genes for RNAi phenotypes. Two groups recently have begun such efforts: Hyman and co-workers [36•] used RNAi to identify those genes on C. elegans chromosome III that affect cell division. Ahringer and co-workers [38•] used RNAi to examine the function of abo ...
... to examine systematically all C. elegans genes for RNAi phenotypes. Two groups recently have begun such efforts: Hyman and co-workers [36•] used RNAi to identify those genes on C. elegans chromosome III that affect cell division. Ahringer and co-workers [38•] used RNAi to examine the function of abo ...
Distinguishing coding from non-coding sequences in a prokaryote
... all coding and non-coding sequences into two sets respectively. A set of 80% of coding/non-coding sequences is regarded as a training set, and the set of the remaining 20% of coding/noncoding sequences as a test set. Fisher’s discriminant algorithm is used to find a classifier in the parameter space ...
... all coding and non-coding sequences into two sets respectively. A set of 80% of coding/non-coding sequences is regarded as a training set, and the set of the remaining 20% of coding/noncoding sequences as a test set. Fisher’s discriminant algorithm is used to find a classifier in the parameter space ...
- American Diabetes Association
... DR3-DQ2 (DRB1*03-DQA1*0501-DQB1*0201) and DR4DQ8 (DRB1*0401-DQA1*0301-DQB1*0302) molecules conferring an ;50% of the total genetic risk. In addition, .40 non-HLA genes with more modest effect on disease risk, such as INS, cytotoxic T-lymphocyte–associated protein 4, protein-tyrosine phosphatase, non ...
... DR3-DQ2 (DRB1*03-DQA1*0501-DQB1*0201) and DR4DQ8 (DRB1*0401-DQA1*0301-DQB1*0302) molecules conferring an ;50% of the total genetic risk. In addition, .40 non-HLA genes with more modest effect on disease risk, such as INS, cytotoxic T-lymphocyte–associated protein 4, protein-tyrosine phosphatase, non ...
Having it both ways: transcription factors that bind DNA and RNA
... by the WT1 gene and contains an N-terminal proline- and glutamine-rich regulatory domain followed by four C-terminal zinc ®ngers (20). Loss of this tumor suppressor protein is associated with pediatric kidney malignancies in Wilms' tumor patients. Interestingly, the primary WT1 transcript is alterna ...
... by the WT1 gene and contains an N-terminal proline- and glutamine-rich regulatory domain followed by four C-terminal zinc ®ngers (20). Loss of this tumor suppressor protein is associated with pediatric kidney malignancies in Wilms' tumor patients. Interestingly, the primary WT1 transcript is alterna ...
Alternative Splicing Analysis Tools Through the UCSC Genome
... against the genome. What is the difference between their score, identity and span? Which measure or combination of measures serves as an indicator for the “best” alignment? 3. Click on the “browser” link of the best alignment (i.e. the first ). The genome browser is now focused on exon 5 of the SL ...
... against the genome. What is the difference between their score, identity and span? Which measure or combination of measures serves as an indicator for the “best” alignment? 3. Click on the “browser” link of the best alignment (i.e. the first ). The genome browser is now focused on exon 5 of the SL ...
ppt - Chair of Computational Biology
... Integrated Analysis of Metabolic and Regulatory Networks Sofar, studies of large-scale cellular networks have focused on their connectivities. The emerging picture shows a densely-woven web where almost everything is connected to everything. In the cell‘s metabolic network, hundreds of substrates ar ...
... Integrated Analysis of Metabolic and Regulatory Networks Sofar, studies of large-scale cellular networks have focused on their connectivities. The emerging picture shows a densely-woven web where almost everything is connected to everything. In the cell‘s metabolic network, hundreds of substrates ar ...
Title PPAR interprets a chromatin signature of - DR-NTU
... embryo manipulation and observation it is noteworthy that PPARb has been originally identified in that species [25]. An important point is also that PPARb is highly expressed in the early embryo whereas PPARa is weak and PPARc absent [25]. This led us to speculate that a major role of PPARb would no ...
... embryo manipulation and observation it is noteworthy that PPARb has been originally identified in that species [25]. An important point is also that PPARb is highly expressed in the early embryo whereas PPARa is weak and PPARc absent [25]. This led us to speculate that a major role of PPARb would no ...
About OMICS Group
... A large proportion of the DEGs between Brassica hexaploid and its parents was involved in biosynthesis of secondary metabolites, plant-pathogen interaction, photosynthesis, and plant hormone signal transduction There were bigger differences on the level of gene expression between the hexaploid an ...
... A large proportion of the DEGs between Brassica hexaploid and its parents was involved in biosynthesis of secondary metabolites, plant-pathogen interaction, photosynthesis, and plant hormone signal transduction There were bigger differences on the level of gene expression between the hexaploid an ...
Supplementary Notes for the work: "Evolutionary Rate and Gene
... regions after controlling for differences in gene expression levels and in expression breadth The mean expression levels (mean expression across all tissues) of the cortical genes are higher than those of non-cortical genes. To control for this potential confounding factor, we removed the cortical g ...
... regions after controlling for differences in gene expression levels and in expression breadth The mean expression levels (mean expression across all tissues) of the cortical genes are higher than those of non-cortical genes. To control for this potential confounding factor, we removed the cortical g ...
B M B 400 Part Four
... regulation. Examples are promoters, enhancers, silencers and LCRs. Matrix and scaffold attachment regions (MARs and SARs) are also hypersensitive to DNase I. ...
... regulation. Examples are promoters, enhancers, silencers and LCRs. Matrix and scaffold attachment regions (MARs and SARs) are also hypersensitive to DNase I. ...
Tools for Comparing Bacterial Genomes
... around 1.2 Mbp, which is strongly curved and easily melted, and is slightly more AT rich than the rest of the genome. Here, the important carbon-monoxide dehydrogenase gene locus is present, as are multiple transposases, which could be an indication of horizontally acquired DNA. The genome is relati ...
... around 1.2 Mbp, which is strongly curved and easily melted, and is slightly more AT rich than the rest of the genome. Here, the important carbon-monoxide dehydrogenase gene locus is present, as are multiple transposases, which could be an indication of horizontally acquired DNA. The genome is relati ...
Giant chromosomes
... • The paired chromosomes of oocytes in meiosis consist of numerous chromatin loops arranged along an axis . Chiasma formation is visible at various locations. • Each segment of a lampbrush chromosome consists of a series of chromatin loops, originating from an axis and a condensed structure, the chr ...
... • The paired chromosomes of oocytes in meiosis consist of numerous chromatin loops arranged along an axis . Chiasma formation is visible at various locations. • Each segment of a lampbrush chromosome consists of a series of chromatin loops, originating from an axis and a condensed structure, the chr ...
RNA Genes: Retroelements and Virally Retroposable microRNAs in
... sections. It is known that ncDNA is predominantly composed of multiple segments of transposable retroelements (TEs) such as, long interspersed elements (LINEs) and, short interspersed elements (SINEs, human Alu), retrotransposons, DNA transposons and satellites (Fig. 1A) [1]. The ncRNAs contain ribo ...
... sections. It is known that ncDNA is predominantly composed of multiple segments of transposable retroelements (TEs) such as, long interspersed elements (LINEs) and, short interspersed elements (SINEs, human Alu), retrotransposons, DNA transposons and satellites (Fig. 1A) [1]. The ncRNAs contain ribo ...
bbr038online 474..484 - Oxford Academic
... (we assume that overlapping contigs have already been merged as part of the assembly process). If the distances between the two putative fragments and the reference gene vary more than a given threshold, the triad is discarded. Indeed, given the hypothesis that both the two or more protein-coding re ...
... (we assume that overlapping contigs have already been merged as part of the assembly process). If the distances between the two putative fragments and the reference gene vary more than a given threshold, the triad is discarded. Indeed, given the hypothesis that both the two or more protein-coding re ...
File
... Other Repetitive DNA, Including Simple Sequence DNA About 15% of the human genome consists of duplication of long sequences of DNA from one location to another In contrast, simple sequence DNA contains many copies of tandemly repeated short sequences ...
... Other Repetitive DNA, Including Simple Sequence DNA About 15% of the human genome consists of duplication of long sequences of DNA from one location to another In contrast, simple sequence DNA contains many copies of tandemly repeated short sequences ...
Document
... Other Repetitive DNA, Including Simple Sequence DNA About 15% of the human genome consists of duplication of long sequences of DNA from one location to another In contrast, simple sequence DNA contains many copies of tandemly repeated short sequences ...
... Other Repetitive DNA, Including Simple Sequence DNA About 15% of the human genome consists of duplication of long sequences of DNA from one location to another In contrast, simple sequence DNA contains many copies of tandemly repeated short sequences ...
On the monophyly of chromalveolates using a six
... molecular phylogenetics. Currently, there are five hypothesized major lineages or ‘supergroups’ of eukaryotes. One of these, the chromalveolates, represents a large fraction of protist and algal diversity. The chromalveolate hypothesis was originally based on similarities between the photosynthetic ...
... molecular phylogenetics. Currently, there are five hypothesized major lineages or ‘supergroups’ of eukaryotes. One of these, the chromalveolates, represents a large fraction of protist and algal diversity. The chromalveolate hypothesis was originally based on similarities between the photosynthetic ...
PowerPoint 프레젠테이션
... of alien genes in filamentous fungi, plants, and animals. - dsRNA is often a byproduct of viral replication or is formed by aberrant transcription from genetic elements after random integration in the host genome. ...
... of alien genes in filamentous fungi, plants, and animals. - dsRNA is often a byproduct of viral replication or is formed by aberrant transcription from genetic elements after random integration in the host genome. ...
Abstract - BioPublisher
... of bases or more(Yang, Adamson et al. 1998).For example, there are two large clusters of imprinted genes on chromosome 7 in the mouse, and there are at least 35 imprinted genes have been discovered on it. The phenomenon of Imprinted genes existing in clusters on chromosome is considered to be due to ...
... of bases or more(Yang, Adamson et al. 1998).For example, there are two large clusters of imprinted genes on chromosome 7 in the mouse, and there are at least 35 imprinted genes have been discovered on it. The phenomenon of Imprinted genes existing in clusters on chromosome is considered to be due to ...
Document
... In prokaryotic cells, you only have one single mRNA that can synthesize more than one protein. One mRNA can translate into several different proteins. In eukaryotic mRNA, a single mRNA codes for one protein. That’s the difference between prokaryotic and eukaryotic mRNA a single eukaryotic mRNA ...
... In prokaryotic cells, you only have one single mRNA that can synthesize more than one protein. One mRNA can translate into several different proteins. In eukaryotic mRNA, a single mRNA codes for one protein. That’s the difference between prokaryotic and eukaryotic mRNA a single eukaryotic mRNA ...
Phylogenetic Affinity of Mitochondria of Euglena
... Cloning of COI-encoding genomic fragment. Mitochondrial DNA was digested with Sau3AI or Taq I and cloned into pBluescript KS− (Stratagene). Several hundred clones were screened with the same PCR-amplified L. tarentolae COI gene fragment as used in the Southern hybridization, and positive clones were ...
... Cloning of COI-encoding genomic fragment. Mitochondrial DNA was digested with Sau3AI or Taq I and cloned into pBluescript KS− (Stratagene). Several hundred clones were screened with the same PCR-amplified L. tarentolae COI gene fragment as used in the Southern hybridization, and positive clones were ...
A CRISPR-based yeast two-hybrid system for investigating
... inserted a multiple-cloning site (MCS) containing five unique, commonly used restrictionenzyme cleavage sites near the 3ʹ end of the sgRNA, four nucleotides 5ʹ of the HDV ribozyme cleavage site. Because at least some of the MCS will ultimately be part of the transcribed hybrid sgRNA (de ...
... inserted a multiple-cloning site (MCS) containing five unique, commonly used restrictionenzyme cleavage sites near the 3ʹ end of the sgRNA, four nucleotides 5ʹ of the HDV ribozyme cleavage site. Because at least some of the MCS will ultimately be part of the transcribed hybrid sgRNA (de ...
A CRISPR-based yeast two-hybrid system for investigating
... inserted a multiple-cloning site (MCS) containing five unique, commonly used restrictionenzyme cleavage sites near the 3ʹ end of the sgRNA, four nucleotides 5ʹ of the HDV ribozyme cleavage site. Because at least some of the MCS will ultimately be part of the transcribed hybrid sgRNA (de ...
... inserted a multiple-cloning site (MCS) containing five unique, commonly used restrictionenzyme cleavage sites near the 3ʹ end of the sgRNA, four nucleotides 5ʹ of the HDV ribozyme cleavage site. Because at least some of the MCS will ultimately be part of the transcribed hybrid sgRNA (de ...