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Antisense derivatives of U7 small nuclear RNA as
Antisense derivatives of U7 small nuclear RNA as

... well as the therapeutic time window, it may be desirable to induce and repress the expression of a U7 cassette at will or to express it specifically in certain tissues or cell types. In this respect it is important to note that the transcription of U snRNA genes is fundamentally different from that ...
Enzymatic cleavage of RNA by RNA
Enzymatic cleavage of RNA by RNA

... Furthermore, work from the laboratories of William McClain (reviewed in McClain, 1977) and John Carbon (Carbon et al., 1974) added to the evidence that RNase P is responsible for the processing of many different tRNA precursor molecules. Although appropriate genetic analyses could not be performed, ...
Whole-genome expression analysis of snf swi mutants of
Whole-genome expression analysis of snf swi mutants of

... The factors that determine the dependence of a gene on Snf兾Swi are not understood. Several studies have indicated that Snf兾Swi may be targeted to particular promoters by physical interactions with specific transcriptional activators or repressors (11–18). However, it seems likely that such interacti ...
MicroRNAs: key participants in gene regulatory networks
MicroRNAs: key participants in gene regulatory networks

... such as rRNAs, tRNAs or snRNAs [10], arguing strongly for a more general function of mRNAs in post-transcriptional regulation. Furthermore, as some miRNAs correspond to the sense strands of mRNAs [5], or are complementary to potential promoter sequences, and CAF has putative nuclear locational signa ...
5 CHAPTER 2: LITERATURE REVIEW 2.1 Types of Ribonucleic
5 CHAPTER 2: LITERATURE REVIEW 2.1 Types of Ribonucleic

... Like cell transcriptional process, the DNA containing miRNAs sequences can reside within intergenic or intronic regions of coding sequence, untranslated region or exonic regions of non-coding sequence. These are transcribed into long miRNA primary transcripts (primiRNAs) by RNA polymerase II (Ambros ...
Document
Document

... There are two ways you can visualize this occurring. ...
Active repressors
Active repressors

... specific regulatory sequences that can bind repression factors ...
A global picture of tRNA genes in plant genomes
A global picture of tRNA genes in plant genomes

... monocots, respectively. The internal or external motifs required for efficient transcription of tRNA genes by RNA polymerase III are well conserved among angiosperms. A brief analysis of the mitochondrial and plastidial tRNA gene populations is also provided. Keywords: alga, angiosperm, non-coding R ...
PDF
PDF

... morphogenetic inactivity of cell nuclei. This would seem paradoxical if the nuclei are supposed to be the sole site for RNA synthesis. This paradox might be resolved, however, if the 'early' RNA synthesis were partly or entirely independent of the cell nuclei. We attempted to clarify this point by m ...
Organization of chromosomes in the interphase cell - UvA-DARE
Organization of chromosomes in the interphase cell - UvA-DARE

... (Dietzel et al., 1998a,b), and the few genes studied so far were not only found near the periphery of a territory, but were also positioned at a certain side of the territory in relation to the remainder of the nucleus (Kurz et al., 1996; Park and DeBoni, 1998). Furthermore, inactive X-chromosomes ( ...
From essential to persistent genes
From essential to persistent genes

... quest for the ‘minimal genome’. However, ‘minimal sets’ of essential genes are strongly context-dependent and, in all prokaryotic genomes sequenced to date, not a single protein-coding gene is entirely conserved. Furthermore, a lack of consensus in the field as to what attributes make a gene truly e ...
Transcription regulation of the Escherichia coli pcnB gene coding for
Transcription regulation of the Escherichia coli pcnB gene coding for

... There are two major eVectors of the stringent response. The Wrst one is a couple of two speciWc nucleotides, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), collectively called (p)ppGpp and rapidly produced in response to variety of physico-chemical and nutritional stresses ( ...
Comparison of genes among cereals
Comparison of genes among cereals

... than those found in Arabidopsis, with globally duplicated genes estimated at 77% [13] and locally duplicated genes at 15–30% depending on the chromosome [13]. These findings are supported by reports from the International Rice Genome Sequencing Project (IRGSP) on rice chromosomes 1 and 4 [15,1 ...
Pulling forces acting on Hox gene clusters cause expression
Pulling forces acting on Hox gene clusters cause expression

... expression intensity systematically increases following the order Hoxd10,…,Hoxd13. The above features of Hox gene collinearity have been meticulously analyzed for more than 25 years in many organisms ranging from Drosophila to humans. Many attempts have been made to justify these surprising regulari ...
current micro 40/5 - Bashan Foundation
current micro 40/5 - Bashan Foundation

... subunits Hox(E)FU have been discussed to also serve as components of the NADH:ubiquinone oxidoreductase of respiratory complex I [1, 4, 5, 33]. In A. variabilis and S. PCC 6803, different ORFs of unknown functions are interspersed within the hox cluster at different positions [4]. In contrast, the h ...
Geuvadis Analysis Meeting
Geuvadis Analysis Meeting

... - Quantified 615 datasets based on the Gencode v7 annotation - Sensitivity is a function of sequencing depth ...
20. Transposable Genetic Elements
20. Transposable Genetic Elements

... McClintock and Marcus Rhoades, yielded results that greatly upset the classical genetic picture of genes residing only at fixed loci on the main chromosome. The research literature began to carry reports suggesting the existence of genetic elements of the main chromosomes that can somehow mobilize t ...
presentation UCSC part 1 - Biomedical Genomics Group
presentation UCSC part 1 - Biomedical Genomics Group

... …are all saved on your computer. When you come back in a couple of days to use it again, these will still be set. You may— or may not—intend this. ...
Brassica genome structure
Brassica genome structure

... •A genome, n=10, B. rapa •B genome, n=8, B. nigra •C genome, n=9, B. oleracea •Why is this important? •Arabidopsis is within Brassica family of 3500 species, many of which have significant agricultural importance. By studying this model organism and exploiting already sequenced genome, candidate gen ...
Full-Text PDF
Full-Text PDF

... However, the mechanism behind the ploidy-related regulation of cell size, cell proliferation and expansion remains largely unclear. In recent years, plant breeders have worked with polyploids in mulberry and several artificially generated polyploids with “larger” mulberry characteristics have been r ...
Antisense derivatives of U7 small nuclear RNA as
Antisense derivatives of U7 small nuclear RNA as

... well as the therapeutic time window, it may be desirable to induce and repress the expression of a U7 cassette at will or to express it specifically in certain tissues or cell types. In this respect it is important to note that the transcription of U snRNA genes is fundamentally different from that ...
Ingenuity Upstream Regulator Analysis in IPA®
Ingenuity Upstream Regulator Analysis in IPA®

... that can explain the observed gene expression changes in a user’s dataset, which can help illuminate the biological  activities occurring in the tissues or cells being studied.  IPA makes it easy to take this result even further by  examining what biological processes, pathways, and diseases the tra ...
Identification of novel micro RNAs and their targets in Cocos
Identification of novel micro RNAs and their targets in Cocos

... Vivek and Faisal Moossa cine zipper protein) has homeodomain (HD) and linear zipper motif present. This class of transcription factors is unique to plants and are involved in plant growth and development especially in response to abscisic acid, abiotic stress, shade avoidance and auxin signaling (A ...
Chpt12_RNAProcessing.doc
Chpt12_RNAProcessing.doc

... (3) These two phosphoester transfers result in a joining of the two exons and excision of the intron (with the initiating G nucleotide attached to the 5' end.) (4) The excised intron is then circularized by attack of the 3'-OH of the last nucleotide of the intron on the phosphate between the 15th an ...
Competition between Transposable Elements
Competition between Transposable Elements

... tations have beneficial effects. However, the fact that they occasionally play important roles in adaptive evolution (Cooper et al. 2001; Schneider and Lenski 2004; Chou et al. 2009) does not imply that they have been directly selected to enhance the rate of evolutionary adaptation (Lynch 2007). Spe ...
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Short interspersed nuclear elements (SINEs)

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