Journal Club Pack - Circulation Research
... pELK-1, KLF4, and HDAC2, with the latter contributing to histone hypo-acetylation, chromatin remodeling, and transcriptional silencing. Studies provide novel evidence that phenotypic switching of SMC in vivo is mediated, at least in part, by binding of the stem cell pluripotency factor KLF4 to a G/C ...
... pELK-1, KLF4, and HDAC2, with the latter contributing to histone hypo-acetylation, chromatin remodeling, and transcriptional silencing. Studies provide novel evidence that phenotypic switching of SMC in vivo is mediated, at least in part, by binding of the stem cell pluripotency factor KLF4 to a G/C ...
Morphology of nuclear transcription | SpringerLink
... or from separate CTs. In the latter case, they can form long-range loops as often observed in coregulated loci during cell differentiation processes (Park et al. 2014). This spatial organization is understood to be pivotal for transcription linking chromatin architecture to coordinated gene expressi ...
... or from separate CTs. In the latter case, they can form long-range loops as often observed in coregulated loci during cell differentiation processes (Park et al. 2014). This spatial organization is understood to be pivotal for transcription linking chromatin architecture to coordinated gene expressi ...
Applied and Environmental Microbiology
... protease genes of B. megaterium and B. stearothermophilus were not amplified by PCR. Sequence analysis revealed that their corresponding primer targets contain numerous mismatches, especially in the inner parts of the primer regions. The PCR-amplified genes of the isolates were subjected to further ...
... protease genes of B. megaterium and B. stearothermophilus were not amplified by PCR. Sequence analysis revealed that their corresponding primer targets contain numerous mismatches, especially in the inner parts of the primer regions. The PCR-amplified genes of the isolates were subjected to further ...
Splice variants of the SWR1-type nucleosome remodeling factor
... incorporation in endoreplicating germline nurse cells appears to be independent of DOM. By contrast, DOM-A promotes the removal of H2A.V from stage 5 nurse cells. Remarkably, therefore, the two DOM isoforms have distinct functions in cell type-specific development and H2A.V exchange. KEY WORDS: Chro ...
... incorporation in endoreplicating germline nurse cells appears to be independent of DOM. By contrast, DOM-A promotes the removal of H2A.V from stage 5 nurse cells. Remarkably, therefore, the two DOM isoforms have distinct functions in cell type-specific development and H2A.V exchange. KEY WORDS: Chro ...
Gene Section RAD52 (RAD52 homolog (S. cerevisiae)) Atlas of Genetics and Cytogenetics
... Shibata T, Yokoyama S. Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. Mol Cell. 2002 ...
... Shibata T, Yokoyama S. Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. Mol Cell. 2002 ...
Chapter C4
... Can you explain the difference between traits and characteristics? Which is more closely associated with DNA and genes? Do you know where DNA and genes are found in the body? In specific cells? Write your answers in your science journal. ...
... Can you explain the difference between traits and characteristics? Which is more closely associated with DNA and genes? Do you know where DNA and genes are found in the body? In specific cells? Write your answers in your science journal. ...
Coordination of replication and transcription along a Drosophila
... arrays of cDNAs have demonstrated a correlation between time of replication and the probability that a specific gene is expressed, it remained to be determined what step(s) in the replication initiation process are influenced by transcription. Similarly, because the prior studies lacked contiguous i ...
... arrays of cDNAs have demonstrated a correlation between time of replication and the probability that a specific gene is expressed, it remained to be determined what step(s) in the replication initiation process are influenced by transcription. Similarly, because the prior studies lacked contiguous i ...
KARNATAKA COMMON ENTRANCE TEST – MAY, 2016 BIOLOGY
... Disclaimer: These solutions are provided by the academic team of BASE. These solutions may be different from those to be provided by the Karnataka Examinations Authority (KEA) due to difference in assumptions taken in support of the solutions. In such cases solution provided by KEA will be deemed as ...
... Disclaimer: These solutions are provided by the academic team of BASE. These solutions may be different from those to be provided by the Karnataka Examinations Authority (KEA) due to difference in assumptions taken in support of the solutions. In such cases solution provided by KEA will be deemed as ...
Synapsis-Mediated Fusion of Free DNA Ends Forms Inverted Dimer Plasmids in Yeast.
... protect a plasmid repair intermediate that would otherwise be destroyed by cellular nucleases. An inverted dimer plasmid could be formed from one plasmid molecule that is replicated after its entry into thecell. Such a mechanism might account for the head-to-head union of the daughter DNA duplexes. ...
... protect a plasmid repair intermediate that would otherwise be destroyed by cellular nucleases. An inverted dimer plasmid could be formed from one plasmid molecule that is replicated after its entry into thecell. Such a mechanism might account for the head-to-head union of the daughter DNA duplexes. ...
Collaborative coupling between polymerase and helicase for
... DNA synthesis by a holoenzyme on a DNA hairpin presents two phases. Initially, the holoenzyme has to open a base pair to incorporate a new nucleotide (strand displacement synthesis activity). This phase gives rise to a large change in extension, typically 0.8 nm for a nucleotide incorporated at 10 ...
... DNA synthesis by a holoenzyme on a DNA hairpin presents two phases. Initially, the holoenzyme has to open a base pair to incorporate a new nucleotide (strand displacement synthesis activity). This phase gives rise to a large change in extension, typically 0.8 nm for a nucleotide incorporated at 10 ...
RecA maintains the integrity of chloroplast DNA molecules in
... Although our understanding of mechanisms of DNA repair in bacteria and eukaryotic nuclei continues to improve, almost nothing is known about the DNA repair process in plant organelles, especially chloroplasts. Since the RecA protein functions in DNA repair for bacteria, an analogous function may exi ...
... Although our understanding of mechanisms of DNA repair in bacteria and eukaryotic nuclei continues to improve, almost nothing is known about the DNA repair process in plant organelles, especially chloroplasts. Since the RecA protein functions in DNA repair for bacteria, an analogous function may exi ...
Free Sample
... ____ 32. A woman with blood group A marries a man with blood group O. Their firstborn child has blood group O. The mother's most probable genotype is: a. OO c. AB b. AA d. AO ____ 33. A structural alteration of DNA in an organism that is caused by a physical or chemical agent is called: a. transcri ...
... ____ 32. A woman with blood group A marries a man with blood group O. Their firstborn child has blood group O. The mother's most probable genotype is: a. OO c. AB b. AA d. AO ____ 33. A structural alteration of DNA in an organism that is caused by a physical or chemical agent is called: a. transcri ...
Ab Initio Modeling of Biological Systems - Psi-k
... However, there are many areas in which the use of effective potentials may be not appropriate, and more sophisticated and accurate approaches are required. An alternative is offered by ab initio molecular dynamics (AIMD). AIMD in the Born-Oppheneimer approximation can be efficiently performed using ...
... However, there are many areas in which the use of effective potentials may be not appropriate, and more sophisticated and accurate approaches are required. An alternative is offered by ab initio molecular dynamics (AIMD). AIMD in the Born-Oppheneimer approximation can be efficiently performed using ...
Complete
... During the research on optimizing Brownian ratchet arrays, we observed a flow effect which can be used for particles separation, and which does not rely on diffusion. This effect is interesting in light of its application to particles separation, because the separation process could occur rapidly. I ...
... During the research on optimizing Brownian ratchet arrays, we observed a flow effect which can be used for particles separation, and which does not rely on diffusion. This effect is interesting in light of its application to particles separation, because the separation process could occur rapidly. I ...
No Slide Title
... • Explain the relationship between DNA, genes, and proteins. • Outline the basic steps in making a protein. • Describe three types of mutations, and provide an example of a gene mutation. ...
... • Explain the relationship between DNA, genes, and proteins. • Outline the basic steps in making a protein. • Describe three types of mutations, and provide an example of a gene mutation. ...
Echinomycin binding to alternating AT
... preceding paper we suggested that the unusual patterns result from secondary binding of echinomycin to the dinucleotide step ApT. This binding is too weak (rapid dissociation?) to yield a footprint but produces DNA structural changes which are sufficiently longlived to be detected by DNase I and DEP ...
... preceding paper we suggested that the unusual patterns result from secondary binding of echinomycin to the dinucleotide step ApT. This binding is too weak (rapid dissociation?) to yield a footprint but produces DNA structural changes which are sufficiently longlived to be detected by DNase I and DEP ...
Charge Transport in DNA - Insights from
... based on thermodynamic observations.[26] Since then, reports have been constantly appearing against,[27] as well as in favor of the thermally induced melting.[28] Importantly, the nature of the overstretched state of DNA probably depends on the rate of stretching. A dsDNA oligomer was reported to de ...
... based on thermodynamic observations.[26] Since then, reports have been constantly appearing against,[27] as well as in favor of the thermally induced melting.[28] Importantly, the nature of the overstretched state of DNA probably depends on the rate of stretching. A dsDNA oligomer was reported to de ...
Recombinant DNA technology and molecular cloning
... can be isolated and amplified. One method of isolation and amplification of a gene of interest is to clone the gene by inserting it into another DNA molecule that serves as a vehicle or vector that can be replicated in living cells. When these two DNAs of different origin are combined, the result is ...
... can be isolated and amplified. One method of isolation and amplification of a gene of interest is to clone the gene by inserting it into another DNA molecule that serves as a vehicle or vector that can be replicated in living cells. When these two DNAs of different origin are combined, the result is ...
Bio.Seq.Seq
... DNA as A,C,T,G RNA as A,C,U,G DNA include all ambiguous base characters: R,Y,W,S,M,K,H,B,V,D and N RNA including the ambiguous base characters DNA including the non-standard bases B, D, S and W Standard amino acid alphabet Amino acids including rare or nonstandard ones ...
... DNA as A,C,T,G RNA as A,C,U,G DNA include all ambiguous base characters: R,Y,W,S,M,K,H,B,V,D and N RNA including the ambiguous base characters DNA including the non-standard bases B, D, S and W Standard amino acid alphabet Amino acids including rare or nonstandard ones ...
Rosalind Elsie Franklin Physicist www.AssignmentPoint.com
... sports. She also learned German, and became fluent in French, a language she would later find useful. She topped her classes, and won annual awards. Her only educational weakness was in music, for which the school music director, the composer Gustav Holst, once called upon her mother to inquire whet ...
... sports. She also learned German, and became fluent in French, a language she would later find useful. She topped her classes, and won annual awards. Her only educational weakness was in music, for which the school music director, the composer Gustav Holst, once called upon her mother to inquire whet ...
Evidence for Variable Selective Pressures at a
... replication are still unknown. In this manuscript, control region and D loop will not be used as synonyms. The increasing amount of available sequences revealed a similar control region structural organization across mammals, with size variation ranging between 880 and 1400 bp (Sbisa et al. 1997). O ...
... replication are still unknown. In this manuscript, control region and D loop will not be used as synonyms. The increasing amount of available sequences revealed a similar control region structural organization across mammals, with size variation ranging between 880 and 1400 bp (Sbisa et al. 1997). O ...
Mitochondrial DNA and aging
... characterized by a time-dependent decline in physiological function [1]. This physiological decline is believed to be associated with an accumulation of defects in the metabolic pathways. RNA, proteins and other cellular macromolecules are rapidly turned over and, consequently, are poor candidates f ...
... characterized by a time-dependent decline in physiological function [1]. This physiological decline is believed to be associated with an accumulation of defects in the metabolic pathways. RNA, proteins and other cellular macromolecules are rapidly turned over and, consequently, are poor candidates f ...
Nucleosome
A nucleosome is a basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool.Nucleosomes form the fundamental repeating units of eukaryotic chromatin, which is used to pack the large eukaryotic genomes into the nucleus while still ensuring appropriate access to it (in mammalian cells approximately 2 m of linear DNA have to be packed into a nucleus of roughly 10 µm diameter). Nucleosomes are folded through a series of successively higher order structures to eventually form a chromosome; this both compacts DNA and creates an added layer of regulatory control, which ensures correct gene expression. Nucleosomes are thought to carry epigenetically inherited information in the form of covalent modifications of their core histones.Nucleosomes were observed as particles in the electron microscope by Don and Ada Olins and their existence and structure (as histone octamers surrounded by approximately 200 base pairs of DNA) were proposed by Roger Kornberg. The role of the nucleosome as a general gene repressor was demonstrated by Lorch et al. in vitro and by Han and Grunstein in vivo.The nucleosome core particle consists of approximately 147 base pairs of DNA wrapped in 1.67 left-handed superhelical turns around a histone octamer consisting of 2 copies each of the core histones H2A, H2B, H3, and H4. Core particles are connected by stretches of ""linker DNA"", which can be up to about 80 bp long. Technically, a nucleosome is defined as the core particle plus one of these linker regions; however the word is often synonymous with the core particle. Genome-wide nucleosome positioning maps are now available for many model organisms including mouse liver and brain.Linker histones such as H1 and its isoforms are involved in chromatin compaction and sit at the base of the nucleosome near the DNA entry and exit binding to the linker region of the DNA. Non-condensed nucleosomes without the linker histone resemble ""beads on a string of DNA"" under an electron microscope.In contrast to most eukaryotic cells, mature sperm cells largely use protamines to package their genomic DNA, most likely to achieve an even higher packaging ratio. Histone equivalents and a simplified chromatin structure have also been found in Archea, suggesting that eukaryotes are not the only organisms that use nucleosomes.