Transcription
... Promoter recognition complexes bind the promoters Classic example: TFIID (TBP and TAFs) Different recognition complexes binding different promoter classes may contribute to cell type specific regulation of transcription 7. CpG islands are a feature of housekeeping genes and reflect the demethylated ...
... Promoter recognition complexes bind the promoters Classic example: TFIID (TBP and TAFs) Different recognition complexes binding different promoter classes may contribute to cell type specific regulation of transcription 7. CpG islands are a feature of housekeeping genes and reflect the demethylated ...
COMPUTATIONAL BIOLOGY
... Although it’s related to a human gene, GenBank entry U90223 doesn’t look very different from entry X01714, the one that describes its bacterial homologue. The top part of the entry follows the general information keywords order: LOCUS, ACCESSION, DEFINITION and VERSION The KEYWORD line, which is sup ...
... Although it’s related to a human gene, GenBank entry U90223 doesn’t look very different from entry X01714, the one that describes its bacterial homologue. The top part of the entry follows the general information keywords order: LOCUS, ACCESSION, DEFINITION and VERSION The KEYWORD line, which is sup ...
nCounter PanCancer Pathways Panel
... All cancers must evolve a means of sustaining self-sufficient growth and evading apoptosis1,2. This process typically occurs via the accumulation of mutational events that confer a growth advantage through deregulation of the molecular pathways controlling cell growth and cell fate3. Mutations in ov ...
... All cancers must evolve a means of sustaining self-sufficient growth and evading apoptosis1,2. This process typically occurs via the accumulation of mutational events that confer a growth advantage through deregulation of the molecular pathways controlling cell growth and cell fate3. Mutations in ov ...
Incomplete Dominance and Codominance
... attempts to identify genetic conditions prior to birth or attempts to predict these conditions prior to conception (Figure 3). Genetic information is obtained through a variety of methods including detailed pedigrees and biochemical testing for known disorders. Methods of prenatal diagnosis can indi ...
... attempts to identify genetic conditions prior to birth or attempts to predict these conditions prior to conception (Figure 3). Genetic information is obtained through a variety of methods including detailed pedigrees and biochemical testing for known disorders. Methods of prenatal diagnosis can indi ...
Tobacco TTG2 regulates vegetative growth and seed production via
... Background: Plant TRANSPARENT TESTA GLABRA (TTG) proteins regulate various developmental activities via the auxin signaling pathway. Recently, we elucidated the developmental role of tobacco (Nicotiana tabacum L.) NtTTG2 in association with 12 genes that putatively encode AUXIN RESPONSIVE FACTOR (AR ...
... Background: Plant TRANSPARENT TESTA GLABRA (TTG) proteins regulate various developmental activities via the auxin signaling pathway. Recently, we elucidated the developmental role of tobacco (Nicotiana tabacum L.) NtTTG2 in association with 12 genes that putatively encode AUXIN RESPONSIVE FACTOR (AR ...
Analysis of a Rhizobium leguminosarum gene
... Helinski, 1979). Tnlac mutagenesis of pBI01000, which contains the gstA and gstR genes cloned in the wide-hostrange plasmid pLAFR1, was performed as follows. pBIOlOOO was transformed into E. coli strain A118, which contains a chromosomally located copy of Tnlac. The resultant strain was used as the ...
... Helinski, 1979). Tnlac mutagenesis of pBI01000, which contains the gstA and gstR genes cloned in the wide-hostrange plasmid pLAFR1, was performed as follows. pBIOlOOO was transformed into E. coli strain A118, which contains a chromosomally located copy of Tnlac. The resultant strain was used as the ...
Identification of Candidate Genes for Rice Grain Aroma by
... environment it is difficult to identify genes that undermine this trait (Pachauri et al. 2010). Initially, it was reported that rice aroma is controlled by a single dominant gene with a segregation ratio of 3:1 (Kadam and Patankar 1938). Subsequently, Jodon (1944) contradicted this observation and r ...
... environment it is difficult to identify genes that undermine this trait (Pachauri et al. 2010). Initially, it was reported that rice aroma is controlled by a single dominant gene with a segregation ratio of 3:1 (Kadam and Patankar 1938). Subsequently, Jodon (1944) contradicted this observation and r ...
Plant Molecular Biology
... common, between Rhizobium species (for a review see [7]). Both common and host-specific nod genes, which are present on large Sym(biosis) plasmids, are thought to be regulated at the transcriptional level as one regulon in which the constitutively expressed nodD product acts as a positive regulator ...
... common, between Rhizobium species (for a review see [7]). Both common and host-specific nod genes, which are present on large Sym(biosis) plasmids, are thought to be regulated at the transcriptional level as one regulon in which the constitutively expressed nodD product acts as a positive regulator ...
Overexpression of miR165 Affects Apical
... Zhong and Ye 2001). Although loss-of-function mutations of individual ATHB-9/PHV, ATHB-14/PHB or ATHB-8 genes do not show any phenotypes, simultaneous loss-of-function mutations of IFL1/REV, ATHB-9/PHV and ATHB-14/PHB cause a loss of SAM and formation of pin-like cotyledons (Prigge et al. 2005). How ...
... Zhong and Ye 2001). Although loss-of-function mutations of individual ATHB-9/PHV, ATHB-14/PHB or ATHB-8 genes do not show any phenotypes, simultaneous loss-of-function mutations of IFL1/REV, ATHB-9/PHV and ATHB-14/PHB cause a loss of SAM and formation of pin-like cotyledons (Prigge et al. 2005). How ...
Review Towards genetic manipulation of wild mosquito populations
... Challenges facing a successful field release The fitness cost of refractoriness To maximize the likelihood of successfully introducing refractory genes into a wild mosquito population, transgenes should impose minimal fitness load. We assessed fitness of transgenic An. stephensi expressing the SM1 a ...
... Challenges facing a successful field release The fitness cost of refractoriness To maximize the likelihood of successfully introducing refractory genes into a wild mosquito population, transgenes should impose minimal fitness load. We assessed fitness of transgenic An. stephensi expressing the SM1 a ...
scylla and charybde, homologues of the human apoptotic gene
... exhibit defects in a subset of dorsally fated cells. Among these more weakly ventralized defects are cyclopia and aberrant head involution (Chang et al., 2003; Wakimoto et al., 1984). While the dpp and zen hypomorphic phenotypes reveal the potential for partitioning of dorsal fates along the anterio ...
... exhibit defects in a subset of dorsally fated cells. Among these more weakly ventralized defects are cyclopia and aberrant head involution (Chang et al., 2003; Wakimoto et al., 1984). While the dpp and zen hypomorphic phenotypes reveal the potential for partitioning of dorsal fates along the anterio ...
TaDAD2, a Negative Regulator of Programmed Cell
... abiotic stress treatments. Wheat seedlings of cv. Suwon 11 were inoculated with race CYR23 (incompatible) or race CYR31 (compatible) of the stripe rust fungus. The abundance of TaDAD2 transcripts in the inoculated leaves was evaluated by qRT-PCR. In leaves inoculated with race CYR23, the expression ...
... abiotic stress treatments. Wheat seedlings of cv. Suwon 11 were inoculated with race CYR23 (incompatible) or race CYR31 (compatible) of the stripe rust fungus. The abundance of TaDAD2 transcripts in the inoculated leaves was evaluated by qRT-PCR. In leaves inoculated with race CYR23, the expression ...
Connecting gene expression data from
... pathways concurrently enrich the understanding of underlying mechanisms. Many researchers have focused their interest on the delineation of gene expression profiles, in order to identify those key genes and gene clusters whose expressions alter disease state.7,8 These gene alteration patterns are id ...
... pathways concurrently enrich the understanding of underlying mechanisms. Many researchers have focused their interest on the delineation of gene expression profiles, in order to identify those key genes and gene clusters whose expressions alter disease state.7,8 These gene alteration patterns are id ...
Documentation for Candidate Gene Prioritization
... This script performs all of the counting, testing, and scoring steps. It uses R (it was written under R version 2.3.1 and is fully compatible with R version 2.4.0). It requires the files ‘GOannotation.txt’, ‘expcounts.txt’, and ‘correl.txt’. The script reads in the file ‘correl.txt’, which contains ...
... This script performs all of the counting, testing, and scoring steps. It uses R (it was written under R version 2.3.1 and is fully compatible with R version 2.4.0). It requires the files ‘GOannotation.txt’, ‘expcounts.txt’, and ‘correl.txt’. The script reads in the file ‘correl.txt’, which contains ...
Natural infection of Run1-positive vines by naïve genotypes of
... mildew infection of the canes is visible as dead, dark brown tissue. ...
... mildew infection of the canes is visible as dead, dark brown tissue. ...
Gene Codon Composition Determines Differentiation
... papillomavirus major capsid (L1) proteins by transient transfection of authentic or codon-modified L1 gene expression plasmids. We demonstrate in vitro and in vivo that gene codon composition is in part responsible for differentiation-dependent expression of L1 protein in KCs. L1 mRNA was present in ...
... papillomavirus major capsid (L1) proteins by transient transfection of authentic or codon-modified L1 gene expression plasmids. We demonstrate in vitro and in vivo that gene codon composition is in part responsible for differentiation-dependent expression of L1 protein in KCs. L1 mRNA was present in ...
Single nucleotide polymorphism in coronary
... and asian groups should not be considered the same in the fields of genetic analysis. Different populations although might be (and should be) investigated for finding the same SNPs increasing susceptibility to ISR, need to be also checked by its genetic potential to cause CAD first and, which seems ...
... and asian groups should not be considered the same in the fields of genetic analysis. Different populations although might be (and should be) investigated for finding the same SNPs increasing susceptibility to ISR, need to be also checked by its genetic potential to cause CAD first and, which seems ...
Commonly Asked Questions
... can be useful for visually comparing different normalization methods. Density plots are produced using the R statistical language with the LIMMA package. ...
... can be useful for visually comparing different normalization methods. Density plots are produced using the R statistical language with the LIMMA package. ...
Blood pressure and human genetic variation in the
... levels that were unambiguous (P value ranging from 1010 to 1070), presumably through shared regulatory effects given the concordant effects on both peptides. With the addition of further samples from Sweden (final n ¼ 29 717), we found that two alleles associated with higher ANP and BNP were also ...
... levels that were unambiguous (P value ranging from 1010 to 1070), presumably through shared regulatory effects given the concordant effects on both peptides. With the addition of further samples from Sweden (final n ¼ 29 717), we found that two alleles associated with higher ANP and BNP were also ...
Nonconventional Initiation Complex Assembly by STAT and NF
... C. viable L. monocytogenes -> similar kinetics of NF-B p65 binding But, STAT1 association required prior IFNI synthesis -> delayed by about 2 hr compared to direct stimulation with IFN-I Binding of NF-κB precedes that of STAT1 and STAT2. ...
... C. viable L. monocytogenes -> similar kinetics of NF-B p65 binding But, STAT1 association required prior IFNI synthesis -> delayed by about 2 hr compared to direct stimulation with IFN-I Binding of NF-κB precedes that of STAT1 and STAT2. ...
Acetate is metabolised in microorganirms
... ilocitrate lycrse in Neurorpora grown on acetate has previously been reported by Turion ( I%2 NN*l:6). Before acetate is metabolized it is firstly converted to its metabolically active form, acetyl-CoA, by the enzyme acetic thiokinase. All enzymes of the glyoxylate cycle ore repressed when Neurorpam ...
... ilocitrate lycrse in Neurorpora grown on acetate has previously been reported by Turion ( I%2 NN*l:6). Before acetate is metabolized it is firstly converted to its metabolically active form, acetyl-CoA, by the enzyme acetic thiokinase. All enzymes of the glyoxylate cycle ore repressed when Neurorpam ...
The Effect of Chromosomal Position on the Expression of the
... generally no larger than single units of genetic function. These are estimated to be about 5-200 kb, based on the amount of DNA associated with single polytene chromosome bands. The resolution of cytogenetic methods is insufficient to provide a detailed picture of the exact relatioship between a rea ...
... generally no larger than single units of genetic function. These are estimated to be about 5-200 kb, based on the amount of DNA associated with single polytene chromosome bands. The resolution of cytogenetic methods is insufficient to provide a detailed picture of the exact relatioship between a rea ...
WheatNet: A genome-scale functional network for hexaploid bread
... expression profiles are one of the most common types of genomic data, and differential expression analysis provides many genes that are potentially associated with given traits such as abiotic and biotic stresses. However, many genes that are associated with stress conditions are not differentially ...
... expression profiles are one of the most common types of genomic data, and differential expression analysis provides many genes that are potentially associated with given traits such as abiotic and biotic stresses. However, many genes that are associated with stress conditions are not differentially ...
View Full Text-PDF
... One family (A) did not show homozygosity shared by affected individuals for the all known candidate genes. However, family B revealed homozygosity at RPE65 genes for two markers, but when typed with additional markers the pattern did not last further. Further analysis showed linkage in a region havi ...
... One family (A) did not show homozygosity shared by affected individuals for the all known candidate genes. However, family B revealed homozygosity at RPE65 genes for two markers, but when typed with additional markers the pattern did not last further. Further analysis showed linkage in a region havi ...
this PDF file - E-Journal Faculty of Medicine Universitas
... In the homozygous state there is a decrease in enzyme functions up to 60%. Meanwhile, in heterozygotes, the decrease is only about 30%. MTHFR C677T polymorphism gene may alter folate metabolism and low folate intake may result in increased levels of homocysteine. This may lead to a decrease in DNA m ...
... In the homozygous state there is a decrease in enzyme functions up to 60%. Meanwhile, in heterozygotes, the decrease is only about 30%. MTHFR C677T polymorphism gene may alter folate metabolism and low folate intake may result in increased levels of homocysteine. This may lead to a decrease in DNA m ...