Role of Cryptic Genes in Microbial Evolution1
... four vitamins at frequencies expected for single-step mutations. Similar results were obtained with a strain of L. acidophilus, indicating the generality of the phenomenon. The nature of the mutations is unknown, but their existence makes it clear that the original auxotrophy did not result from mul ...
... four vitamins at frequencies expected for single-step mutations. Similar results were obtained with a strain of L. acidophilus, indicating the generality of the phenomenon. The nature of the mutations is unknown, but their existence makes it clear that the original auxotrophy did not result from mul ...
Imprinted gene expression in hybrids: perturbed
... so far suggest that loss of imprinting occurs similarly in the hybrids derived from the reciprocal crosses (Shi et al., 2004, 2005). It is unknown whether this is responsible for the less pronounced phenotypic difference between the reciprocal hybrids than in the Peromyscus crosses. (MU S)F1 adult ...
... so far suggest that loss of imprinting occurs similarly in the hybrids derived from the reciprocal crosses (Shi et al., 2004, 2005). It is unknown whether this is responsible for the less pronounced phenotypic difference between the reciprocal hybrids than in the Peromyscus crosses. (MU S)F1 adult ...
Pseudogenes as regulators of biological function
... Duplicated pseudogenes may be formed with mutations or deletions in their promoters, and processed pseudogenes may become integrated into transcriptionally silent regions of the genome. Assessing levels of pseudogene RNA can be difficult due to close homology with the original gene from which it was ...
... Duplicated pseudogenes may be formed with mutations or deletions in their promoters, and processed pseudogenes may become integrated into transcriptionally silent regions of the genome. Assessing levels of pseudogene RNA can be difficult due to close homology with the original gene from which it was ...
Quantitation and Purification of Acquired Plasmid DNA Coding for
... depends on many variables, especially selective pressures. Gene transfer also depends on independent strains including their individual characteristics for genetic transfer. In addition to these variables and parameters, the various environmental parameters play a significant role in plasmid transfe ...
... depends on many variables, especially selective pressures. Gene transfer also depends on independent strains including their individual characteristics for genetic transfer. In addition to these variables and parameters, the various environmental parameters play a significant role in plasmid transfe ...
5` Flanking Sequences of the Rat Tyrosine Hydroxylase Gene Target
... express TH at different times, and are functionally and anatomically distinct (Specht et al., 198 la; Bjorklund and Lindvall, 1984). The mechanism responsible for TH expression in such disparate cell groups might be expected to rely on multiple regulatory elements, some that may be needed in all TH ...
... express TH at different times, and are functionally and anatomically distinct (Specht et al., 198 la; Bjorklund and Lindvall, 1984). The mechanism responsible for TH expression in such disparate cell groups might be expected to rely on multiple regulatory elements, some that may be needed in all TH ...
Hemophilia
... Women have two copies of the X chromosome (XX); They are not affected but they are genetic carriers for hemophilia. Males have only one X chromosome and a Y (XY); those with a faulty clotting factor gene on their X chromosome will have Hemophilia. ...
... Women have two copies of the X chromosome (XX); They are not affected but they are genetic carriers for hemophilia. Males have only one X chromosome and a Y (XY); those with a faulty clotting factor gene on their X chromosome will have Hemophilia. ...
ppt - Chair of Computational Biology
... Recurrence signature algorithm Availability of DNA microarray data study transcriptional response of a complete genome to different experimental conditions. An essential task in studying the global structure of transcriptional networks is the gene classification. Commonly used clustering algorith ...
... Recurrence signature algorithm Availability of DNA microarray data study transcriptional response of a complete genome to different experimental conditions. An essential task in studying the global structure of transcriptional networks is the gene classification. Commonly used clustering algorith ...
Transmission disequilibrium test and haplotype analysis of the MCP-1
... studies [4-6] demonstrated that TS is familial, and twin studies provided evidence that genetic factors are important in its transmission [7,8]. However, until now, no common vulnerability genes, which clearly associated with the disorder have been reported. In spite of hereditary factor, postinfect ...
... studies [4-6] demonstrated that TS is familial, and twin studies provided evidence that genetic factors are important in its transmission [7,8]. However, until now, no common vulnerability genes, which clearly associated with the disorder have been reported. In spite of hereditary factor, postinfect ...
Chromatin regulates origin activity in Drosophila follicle cells
... clones most frequently having redistributed ORC2 (Fig. 3e–j and Supplementary Fig. S8). Among Rpd3-mutant clones comprised of five or fewer cells, 20% (n ¼ 41) had at least one large nucleus, and measurement of total 4,6-diamidino-2-phenylindole (DAPI) fluorescence indicated that they contained appr ...
... clones most frequently having redistributed ORC2 (Fig. 3e–j and Supplementary Fig. S8). Among Rpd3-mutant clones comprised of five or fewer cells, 20% (n ¼ 41) had at least one large nucleus, and measurement of total 4,6-diamidino-2-phenylindole (DAPI) fluorescence indicated that they contained appr ...
Précis - Scoliosis and Spinal Disorders
... disease pathways have been pointed out [26]. Furthermore, associations studies are based on the preliminary assumption that offspring genotypes are always formed strictly following Mendelian probabilities, but there is some evidence that transmission distortions could occur for some human genome loc ...
... disease pathways have been pointed out [26]. Furthermore, associations studies are based on the preliminary assumption that offspring genotypes are always formed strictly following Mendelian probabilities, but there is some evidence that transmission distortions could occur for some human genome loc ...
Chinese company edits pig DNA, develops piglets that will stay pet
... Another question is how far gene editing should go. ...
... Another question is how far gene editing should go. ...
Glucose Regulation of Transforming Growth Factor
... example, insulin gene expression is stimulated by glucose in rat pancreatic @cell cultures (1, 2). Glucose also up-regulates the expression of the S14 gene in rat primary hepatocytes (3, 4) and basement membrane components in cultured human endotheiial cells (5, 6). We recently demonstrated that glu ...
... example, insulin gene expression is stimulated by glucose in rat pancreatic @cell cultures (1, 2). Glucose also up-regulates the expression of the S14 gene in rat primary hepatocytes (3, 4) and basement membrane components in cultured human endotheiial cells (5, 6). We recently demonstrated that glu ...
Syndromes of the first and second pharyngeal arches
... premature termination codons, leading to haploinsuficiency of the protein treacle and causing TCS. Low amount of treacle leads ultimately to a reduction in the number of cranial neural crest cells migrating to the first and second pharyngeal arches. Other than TCS, the genes associated with ACS and ...
... premature termination codons, leading to haploinsuficiency of the protein treacle and causing TCS. Low amount of treacle leads ultimately to a reduction in the number of cranial neural crest cells migrating to the first and second pharyngeal arches. Other than TCS, the genes associated with ACS and ...
GUEST COMMENTARY
... employed. Benzer and Champe (5) isolated this fusion, which is called deletion r1589. (Unfortunately, such free exchange of ideas and reagents is less common today.) In wild-type T4, the rIIA and rIIB genes are adjacent, and they are transcribed independently from the same DNA strand. Deletion r1589 ...
... employed. Benzer and Champe (5) isolated this fusion, which is called deletion r1589. (Unfortunately, such free exchange of ideas and reagents is less common today.) In wild-type T4, the rIIA and rIIB genes are adjacent, and they are transcribed independently from the same DNA strand. Deletion r1589 ...
Functional significance of the discordance between
... Characterization of tTA-TRAF2 mice. Figure 1 shows that the tTA-TRAF2 mice develop a dilated HF phenotype at 12 weeks, characterized by an increased heart weight–to–body weight (HW/BW) ratio (P < 0.05), increased LV dilation (P < 0.05), decreased fractional shortening, and adverse LV remodeling as d ...
... Characterization of tTA-TRAF2 mice. Figure 1 shows that the tTA-TRAF2 mice develop a dilated HF phenotype at 12 weeks, characterized by an increased heart weight–to–body weight (HW/BW) ratio (P < 0.05), increased LV dilation (P < 0.05), decreased fractional shortening, and adverse LV remodeling as d ...
Letter Neighboring Genes Show
... 2004). Closely located genes show more similar gene expression patterns than randomly chosen gene pairs. The general phenomenon of coexpression of neighboring genes has been reported in several model eukaryotes such as Saccharomyces cerevisiae (Kruglyak and Tang 2000; Fukuoka et al. 2004; Lercher an ...
... 2004). Closely located genes show more similar gene expression patterns than randomly chosen gene pairs. The general phenomenon of coexpression of neighboring genes has been reported in several model eukaryotes such as Saccharomyces cerevisiae (Kruglyak and Tang 2000; Fukuoka et al. 2004; Lercher an ...
Correlations Between Gene Expression and Gene Conservation in
... (Schizosaccharomyces pombe) with lists of “core” genes (present in worm and budding and fission yeasts), “yeast-specific” genes (present in budding and fission yeasts, but not in worm), and “pombe-specific” genes (present in fission yeast only). Whereas a disproportionate number of core genes are hi ...
... (Schizosaccharomyces pombe) with lists of “core” genes (present in worm and budding and fission yeasts), “yeast-specific” genes (present in budding and fission yeasts, but not in worm), and “pombe-specific” genes (present in fission yeast only). Whereas a disproportionate number of core genes are hi ...
A criticism of the value of midparent in
... et al., 2004; Jarosz et al., 2010). Nevertheless, in maize, even expression for most proteins increases linearly with ploidy (Yao et al., 2011). Polyploid derivatives of inbred maize lines, however, are less vigorous than the diploid progenitor (Yao et al., 2011), so down-modulation must occur at ...
... et al., 2004; Jarosz et al., 2010). Nevertheless, in maize, even expression for most proteins increases linearly with ploidy (Yao et al., 2011). Polyploid derivatives of inbred maize lines, however, are less vigorous than the diploid progenitor (Yao et al., 2011), so down-modulation must occur at ...
Microarray data normalization and data transformation
... There are a number of schools of thought regarding the estimation of background for DNA microarrays (1) Not to calculate a background value • But rather to try to estimate it using statistical techniques • Argument – subtracting background introduces significant variance into the estimation of hybri ...
... There are a number of schools of thought regarding the estimation of background for DNA microarrays (1) Not to calculate a background value • But rather to try to estimate it using statistical techniques • Argument – subtracting background introduces significant variance into the estimation of hybri ...
Human, yeast and hybrid 3-phosphoglycerate kinase gene
... expression unit b, protein levels of all hPGK containing expression units are significantly decreased. Differences in migration of the various PGKs are due to differences in amino acid compositions (15). The above results are summarized in Table 1. mRNA Production by the Different Expression Units F ...
... expression unit b, protein levels of all hPGK containing expression units are significantly decreased. Differences in migration of the various PGKs are due to differences in amino acid compositions (15). The above results are summarized in Table 1. mRNA Production by the Different Expression Units F ...
Distinct Roles for Drosophila Dicer-1 and Dicer
... dsRNA processing depletion of dicer results in reduced effectiveness of injected siRNA Dicer binds to components of RISC (R2D2) & binds tightly to siRNA Role of Dicer in siRISC is not well characterized… The authors took a genetic approach to study Dicer function in Drosophila ...
... dsRNA processing depletion of dicer results in reduced effectiveness of injected siRNA Dicer binds to components of RISC (R2D2) & binds tightly to siRNA Role of Dicer in siRISC is not well characterized… The authors took a genetic approach to study Dicer function in Drosophila ...
Draft breeding policy - Balinese Breed Advisory Committee
... Many of the genes have mutated to slightly different forms, selection of these has resulted in the development of different physical characteristics which are the basis of the various breeds. The variant forms of a gene are called alleles. When a particular gene pair consists of different alleles, w ...
... Many of the genes have mutated to slightly different forms, selection of these has resulted in the development of different physical characteristics which are the basis of the various breeds. The variant forms of a gene are called alleles. When a particular gene pair consists of different alleles, w ...
WebGestaltR
... may cause some categories with outputted leading edge genes are not included in the final result even if the number of significant categories is larger than lNum. 24. is.output: If is.output is TRUE, WebGestaltR will create a folder named by the projectName and save the mapping results, GO slim summ ...
... may cause some categories with outputted leading edge genes are not included in the final result even if the number of significant categories is larger than lNum. 24. is.output: If is.output is TRUE, WebGestaltR will create a folder named by the projectName and save the mapping results, GO slim summ ...