Characterization of the wheat gene encoding a grain
... a few genes are known to be specifically expressed in the ESR. These are ZmEsr1-3 (Opsahl-Ferstad et al., 1997; Bonello et al., 2000), ZmAE1 and ZmAE3 (Magnard et al., 2000), and ZmESR-6 (Balandin et al., 2005). Identification of these ESR-specific genes confirmed ESR cells as a separate domain of g ...
... a few genes are known to be specifically expressed in the ESR. These are ZmEsr1-3 (Opsahl-Ferstad et al., 1997; Bonello et al., 2000), ZmAE1 and ZmAE3 (Magnard et al., 2000), and ZmESR-6 (Balandin et al., 2005). Identification of these ESR-specific genes confirmed ESR cells as a separate domain of g ...
Familial Mediterranean Fever (FMF) factsheet for patients
... about 25,000 different genes, which is more than a chicken but less than a tomato. Each cell contains two copies of each gene, one from each of our parents. Within each cell, the genes are arranged into 46 long strings, called ...
... about 25,000 different genes, which is more than a chicken but less than a tomato. Each cell contains two copies of each gene, one from each of our parents. Within each cell, the genes are arranged into 46 long strings, called ...
The Genetic Control and Cytoplasmic Expression of "Inducibility" in
... Let UB emphasize that this sketch of the Lac region is preliminary and very incomplete, and that the results concerning the relationshipe of certain markers are not understood. For instance, the i marker recombines rather freely with all the other mutants shown (both y and .) yet, by cotransduction ...
... Let UB emphasize that this sketch of the Lac region is preliminary and very incomplete, and that the results concerning the relationshipe of certain markers are not understood. For instance, the i marker recombines rather freely with all the other mutants shown (both y and .) yet, by cotransduction ...
Isolation and Characterization of Mutations in the b-Tubulin Gene of Saccharomyces cerevisiae .
... fragment of E. coli DNA polymerase I (ROSEand BOTSTEIN 1983), followed by phenol extraction and ethanol precipitation. Phosphorylated BamHI linkers (10-mers, Collaborative Research) were ligated to the DNA (linker:pJT71 DNA molar ratio, about 50:1), excess linkers were removed by agarose gel electro ...
... fragment of E. coli DNA polymerase I (ROSEand BOTSTEIN 1983), followed by phenol extraction and ethanol precipitation. Phosphorylated BamHI linkers (10-mers, Collaborative Research) were ligated to the DNA (linker:pJT71 DNA molar ratio, about 50:1), excess linkers were removed by agarose gel electro ...
Regulation of secondary metabolism in streptomycetes
... metabolism is consistent with much of the published literature. Given its likely participation in the growth rate control of gene expression in unicellular bacteria [8], the role of the highly phosphorylated guanosine nucleotide (p)ppGpp in triggering antibiotic production in streptomycetes has rece ...
... metabolism is consistent with much of the published literature. Given its likely participation in the growth rate control of gene expression in unicellular bacteria [8], the role of the highly phosphorylated guanosine nucleotide (p)ppGpp in triggering antibiotic production in streptomycetes has rece ...
externial ophtlhalmiioplegila has been reported as inherited in two
... family is recessive and sex-linked. As far as we have been able to discover in the literature there is no earlier reference to inheritance of this ty-pe for this particular disease. The clinical and neurological examination carried out by one of us (J. C. (). de Z.) on all fourteen living members of ...
... family is recessive and sex-linked. As far as we have been able to discover in the literature there is no earlier reference to inheritance of this ty-pe for this particular disease. The clinical and neurological examination carried out by one of us (J. C. (). de Z.) on all fourteen living members of ...
Imprinted Genes and Human Disease
... of mutations of imprinted genes. We ask whether we should expect that imprinted genes are particularly fragile. That is, are they more likely to undergo mutation and/or are mutations of imprinted genes particularly likely to result in human disease? In general we consider how the field of evolutiona ...
... of mutations of imprinted genes. We ask whether we should expect that imprinted genes are particularly fragile. That is, are they more likely to undergo mutation and/or are mutations of imprinted genes particularly likely to result in human disease? In general we consider how the field of evolutiona ...
Regulatory sequences of H19 and IGF2 genes in DNA‐based
... and limits their ability to be administered iteratively. Based on early studies from our group and others, transcriptional regulatory sequences of the H19 gene have emerged as candidates for cancer gene therapy. H19 is a paternally imprinted, oncofetal gene that encodes a RNA (with no protein produc ...
... and limits their ability to be administered iteratively. Based on early studies from our group and others, transcriptional regulatory sequences of the H19 gene have emerged as candidates for cancer gene therapy. H19 is a paternally imprinted, oncofetal gene that encodes a RNA (with no protein produc ...
Opportunistic screening for haemochromatosis
... found in very low frequency. The H63D is an older mutation. • Type 1, the most common, is an autosomal recessive condition caused by a mutation in HFE which was the first haemochromatosis gene identified and primarily found in northern Europeans. A single mutation in HFE results in the substituting ...
... found in very low frequency. The H63D is an older mutation. • Type 1, the most common, is an autosomal recessive condition caused by a mutation in HFE which was the first haemochromatosis gene identified and primarily found in northern Europeans. A single mutation in HFE results in the substituting ...
My favourite flowering image: a cob of pod corn
... 2004). The piece was termed a ‘minireview’ but, in the case of the Tunicate story, it reported results almost a decade before they were actually published so that ‘preview’ would have been a more appropriate term. In the same year we submitted the sequence of ZMM19 from Tunicate to GenBank. This obv ...
... 2004). The piece was termed a ‘minireview’ but, in the case of the Tunicate story, it reported results almost a decade before they were actually published so that ‘preview’ would have been a more appropriate term. In the same year we submitted the sequence of ZMM19 from Tunicate to GenBank. This obv ...
jsm2003 - University of Wisconsin–Madison
... • (Henderson et al. Hoeschele 2001; Ong Page 2002) ...
... • (Henderson et al. Hoeschele 2001; Ong Page 2002) ...
Regulation of phenylalanine biosynthesis in Escherichia coli K
... several genes concerned with aromatic amino acid biosynthesis, rendering it extremely sensitive to low levels of p-FPA. In the course of attempts to isolate and characterize FPA-resistant mutants in this strain, we unexpectedly discovered that a spontaneously isolated rifampin-resistant derivative o ...
... several genes concerned with aromatic amino acid biosynthesis, rendering it extremely sensitive to low levels of p-FPA. In the course of attempts to isolate and characterize FPA-resistant mutants in this strain, we unexpectedly discovered that a spontaneously isolated rifampin-resistant derivative o ...
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... The other two QTTs had positive effects on lint yield, indicating that high expression levels of these QTTs could result in increased lint yield. 2.2 Contributed genetic effects of the QTTs on lint yield and its component traits The predicted additive effects and the contributed effects of the six s ...
... The other two QTTs had positive effects on lint yield, indicating that high expression levels of these QTTs could result in increased lint yield. 2.2 Contributed genetic effects of the QTTs on lint yield and its component traits The predicted additive effects and the contributed effects of the six s ...
Accepted version - Queen Mary University of London
... TcNTR, we sequenced the gene from 28 Colombian strains of different biological and geographical origins and with a range of benznidazole-sensitivities (IC50 1.5 - 35 μM) (Table 1). TcNTR length varied between 939 - 951 nucleotides in these strains, mainly due to changes in the copy number of a trinu ...
... TcNTR, we sequenced the gene from 28 Colombian strains of different biological and geographical origins and with a range of benznidazole-sensitivities (IC50 1.5 - 35 μM) (Table 1). TcNTR length varied between 939 - 951 nucleotides in these strains, mainly due to changes in the copy number of a trinu ...
UNIFR Rusconi 2002
... Basic understanding of 'genes and genomes': what is a gene, how many genes, molecular biology dogma genetic diseases, environmental factors, Essential concepts on 'molecular medicine' applications and problems, ageing as the major disease Genomics and other 'omics' essential technologies Application ...
... Basic understanding of 'genes and genomes': what is a gene, how many genes, molecular biology dogma genetic diseases, environmental factors, Essential concepts on 'molecular medicine' applications and problems, ageing as the major disease Genomics and other 'omics' essential technologies Application ...
Genomics - Pearson Canada
... gene-sized stretches of sequence range from several hundred bases to thousands of bases. In addition, the computer programs look for sequences typical of promoters, operators, or other regulatory sites. DNA segments that are identified in this way are called open reading frames, or ORFs. Once an ORF ...
... gene-sized stretches of sequence range from several hundred bases to thousands of bases. In addition, the computer programs look for sequences typical of promoters, operators, or other regulatory sites. DNA segments that are identified in this way are called open reading frames, or ORFs. Once an ORF ...
Introduction: - Statistical Science
... and over-weighted (p=2) enrichment statistics. We used GSEA to analyze gene expression profiles from bone marrow of individuals with Downs syndrome (DS, n=14) and control individuals (n=25) [Aravind add ref]. When we probe the dataset with GSEA and the un-weighted p=0 statistic using the set of all ...
... and over-weighted (p=2) enrichment statistics. We used GSEA to analyze gene expression profiles from bone marrow of individuals with Downs syndrome (DS, n=14) and control individuals (n=25) [Aravind add ref]. When we probe the dataset with GSEA and the un-weighted p=0 statistic using the set of all ...
Diapositive 1 - Institut Pasteur
... Effect of expression of certain PE_PGRS genes in the non pathogenic M. smegmatis ● M. Smegmatis expressing PE_PGRS33 displayed enhanced colonization of BMM macropahages and increased cell necrosis (Dheenadhayalan et al., 2005) ...
... Effect of expression of certain PE_PGRS genes in the non pathogenic M. smegmatis ● M. Smegmatis expressing PE_PGRS33 displayed enhanced colonization of BMM macropahages and increased cell necrosis (Dheenadhayalan et al., 2005) ...
Solid Tumour Section Soft tissue tumors: t(1;13)(p36;q14) in alveolar rhabdomyosarcoma
... The fusion gene has a 2484 nt open reading frame encoding an 828 amino acid fusion protein. This fusion protein is a transcription factor with a PAX7 DNA binding domain and FOXO1 transactivation domain. Expression / Localisation Nuclear. Oncogenesis Transcription dysregulation. At the cellular level ...
... The fusion gene has a 2484 nt open reading frame encoding an 828 amino acid fusion protein. This fusion protein is a transcription factor with a PAX7 DNA binding domain and FOXO1 transactivation domain. Expression / Localisation Nuclear. Oncogenesis Transcription dysregulation. At the cellular level ...
A nomenclature for restriction enzymes, DNA methyltransferases
... their protein products are HsdR, HsdM and HsdS, respectively. The protein products can be abbreviated by omitting Hsd. The S subunit is the speci®city subunit that determines which DNA sequence is recognized. The R subunit is essential for cleavage (restriction) and the M subunit catalyzes the methy ...
... their protein products are HsdR, HsdM and HsdS, respectively. The protein products can be abbreviated by omitting Hsd. The S subunit is the speci®city subunit that determines which DNA sequence is recognized. The R subunit is essential for cleavage (restriction) and the M subunit catalyzes the methy ...
University of Birmingham Immunolabelling of human metaphase
... Our previously published work described how immunofluorescence microscopy could be used to provide an overview of the distribution of histone modifications across human metaphase chromosomes. Using metaphase chromosome spreads from lymphoblastoid cell lines (LCL) of normal karyotype and antisera to ...
... Our previously published work described how immunofluorescence microscopy could be used to provide an overview of the distribution of histone modifications across human metaphase chromosomes. Using metaphase chromosome spreads from lymphoblastoid cell lines (LCL) of normal karyotype and antisera to ...
Methods of screening for bioactive agents using cells transformed
... draWbacks. First, the presence of viral promoters at the 5‘ long terminal repeats (LTR) may result in mobiliZation or rescue of an integrated provirus by endogenous retroviruses or upon infection With retroviral vectors that express viral ...
... draWbacks. First, the presence of viral promoters at the 5‘ long terminal repeats (LTR) may result in mobiliZation or rescue of an integrated provirus by endogenous retroviruses or upon infection With retroviral vectors that express viral ...
Gene Expression Microarray Analysis of Archival FFPE Samples
... formalin-fixed paraffin-embedded (FFPE) tissues are the only samples available. To work with these difficult samples, Agilent has developed an FFPE sample protocol optimized for use with Agilent gene expression microarrays. To test the effectiveness of this protocol, total RNA was extracted from a q ...
... formalin-fixed paraffin-embedded (FFPE) tissues are the only samples available. To work with these difficult samples, Agilent has developed an FFPE sample protocol optimized for use with Agilent gene expression microarrays. To test the effectiveness of this protocol, total RNA was extracted from a q ...
Case Study #5 - davis.k12.ut.us
... pass this to half of her sons who will have the disease, and half of her daughters who will be carriers. 19. The hemophilia trait is carried on the x chromosome. Males have only one x chromosome, therefore, if they have the hemophilia trait on the x chromosome they will have the disease. Females hav ...
... pass this to half of her sons who will have the disease, and half of her daughters who will be carriers. 19. The hemophilia trait is carried on the x chromosome. Males have only one x chromosome, therefore, if they have the hemophilia trait on the x chromosome they will have the disease. Females hav ...
WSJ - Nov 2006 - Augie`s Quest
... For the gene search, the team needed DNA from more than a thousand ALS patients. Doctors and medical centers with stored blood samples didn't give them up easily. Some worried about patient confidentiality, and others wanted a financial cut. Pressed by Mr. Nieto's constant urging for speed, the TGen ...
... For the gene search, the team needed DNA from more than a thousand ALS patients. Doctors and medical centers with stored blood samples didn't give them up easily. Some worried about patient confidentiality, and others wanted a financial cut. Pressed by Mr. Nieto's constant urging for speed, the TGen ...