The UCSC Known Genes
... Select best mRNA for each protein. A set of candidate mRNA alignments are selected from the filtered mRNAs that aligned to the genome and have corresponding protein sequences in the Swiss-Prot/TrEMBL data as determined via the cross-reference table spXref2. For hg17, this list contains 74 290 entrie ...
... Select best mRNA for each protein. A set of candidate mRNA alignments are selected from the filtered mRNAs that aligned to the genome and have corresponding protein sequences in the Swiss-Prot/TrEMBL data as determined via the cross-reference table spXref2. For hg17, this list contains 74 290 entrie ...
Non-syndromic progressive hearing loss DFNA38 is caused by
... The neurologic exam was completely normal. Renal ultrasound was normal. In summary, VI:3 has features of Wolfram syndrome, specifically juvenile diabetes mellitus and cataracts, but lacks the optic atrophy that is part of the definition of the complete syndrome. The attenuated disease phenotype of V ...
... The neurologic exam was completely normal. Renal ultrasound was normal. In summary, VI:3 has features of Wolfram syndrome, specifically juvenile diabetes mellitus and cataracts, but lacks the optic atrophy that is part of the definition of the complete syndrome. The attenuated disease phenotype of V ...
Divergence with Gene Flow: Models and Data
... The BDM model invokes two mechanisms for preventing the spread of alleles that have become fixed in one population into the other population. The first is geographic separation and the second, that kicks in when hybrids are produced, is epistatic incompatibility between alleles that have become fixed i ...
... The BDM model invokes two mechanisms for preventing the spread of alleles that have become fixed in one population into the other population. The first is geographic separation and the second, that kicks in when hybrids are produced, is epistatic incompatibility between alleles that have become fixed i ...
Examination of G72 and D-amino-acid oxidase
... also contribute to the development of bipolar affective disorder (BPAD) for two reasons: first, although schizophrenia and BPAD are characterized by distinct clinical patterns of symptoms, a variety of psychopathological features are shared between these two disease entities. This has brought forwar ...
... also contribute to the development of bipolar affective disorder (BPAD) for two reasons: first, although schizophrenia and BPAD are characterized by distinct clinical patterns of symptoms, a variety of psychopathological features are shared between these two disease entities. This has brought forwar ...
draft - University of Michigan
... Recessivity of new mutations might favor faster-X trans-regulatory divergence A key component of the theoretical work predicting faster-X evolution is that the effects of new mutations are at least partially recessive (Charlesworth et al. 1987). If systematic differences in dominance exist between ...
... Recessivity of new mutations might favor faster-X trans-regulatory divergence A key component of the theoretical work predicting faster-X evolution is that the effects of new mutations are at least partially recessive (Charlesworth et al. 1987). If systematic differences in dominance exist between ...
Imunocytochemistry Detection of M1CA Gene Receptor in Human P
... intestinal epithelium cells . and epithelium-derived tumours (Groh, 1996; Groh, 1999 ) . MICA gene with Brucella was played important role at susceptibility and protection in human Brucellosis . The MICA chain is stress-induced when infection with Brucella occurrence in acute or chronic cases. The m ...
... intestinal epithelium cells . and epithelium-derived tumours (Groh, 1996; Groh, 1999 ) . MICA gene with Brucella was played important role at susceptibility and protection in human Brucellosis . The MICA chain is stress-induced when infection with Brucella occurrence in acute or chronic cases. The m ...
Local gene density predicts the spatial position of genetic loci in the
... pinhole for all scans was kept constant at 1 Airy. All 3D image stacks of fixed cells were acquired with steps between 0.2 Am and 0.5 Am in z-directions. Preferably, the same step increments were used for each experimental series. The image resolution was 512 512 pixels. If two or more fluorochrom ...
... pinhole for all scans was kept constant at 1 Airy. All 3D image stacks of fixed cells were acquired with steps between 0.2 Am and 0.5 Am in z-directions. Preferably, the same step increments were used for each experimental series. The image resolution was 512 512 pixels. If two or more fluorochrom ...
Epsilon Toxin Characterization
... Materials and Methods Bacterial strains and culture conditions: Bacterial strains were obtained from the ATCC Bacteriology collection and were grown in reinforced clostridial media ATCC #1053. All strains were cultured under anaerobic conditions at 37°C. Cultures were plated on Tryptic Soy Agar with ...
... Materials and Methods Bacterial strains and culture conditions: Bacterial strains were obtained from the ATCC Bacteriology collection and were grown in reinforced clostridial media ATCC #1053. All strains were cultured under anaerobic conditions at 37°C. Cultures were plated on Tryptic Soy Agar with ...
Dairy cattle reproduction is a tightly regulated genetic process
... there is a large amount of evidence supporting the role of the oocyte in regulating follicle growth and development, and thereby its own development, by the production of oocyte growth factors acting on supporting granulosa cells. In addition, intensive bi-directional exchanges of nutritive and sign ...
... there is a large amount of evidence supporting the role of the oocyte in regulating follicle growth and development, and thereby its own development, by the production of oocyte growth factors acting on supporting granulosa cells. In addition, intensive bi-directional exchanges of nutritive and sign ...
Lin, R., C. D. Allis and S. J. Elledge. 1996. PAT1
... between chH1 and lacZ (data not shown). A genetic screen was performed to identify mutants whose growth is dependent on the expression of chH1. These mutants are expected to be defective either in the yeast histone H1 homologue or other genes that are suppressible by chicken H1 protein. Cells with l ...
... between chH1 and lacZ (data not shown). A genetic screen was performed to identify mutants whose growth is dependent on the expression of chH1. These mutants are expected to be defective either in the yeast histone H1 homologue or other genes that are suppressible by chicken H1 protein. Cells with l ...
Characterization of the trans-spliced transcriptome and polycistronic
... In nematodes, spliced leader (SL) trans-splicing is associated with processing of polycistronic transcription units (PTU) into translatable mRNAs. Although SL trans-splicing is employed by all major lineages of flatworms, extensive information on the trans-spliced transcriptome in these organisms or ...
... In nematodes, spliced leader (SL) trans-splicing is associated with processing of polycistronic transcription units (PTU) into translatable mRNAs. Although SL trans-splicing is employed by all major lineages of flatworms, extensive information on the trans-spliced transcriptome in these organisms or ...
Mechanisms Underlying the Evolution and Maintenance of
... unclear. Therefore, the aim of this study was to investigate what processes underlie the long-term evolution of apicomplexan 18S genes in representative species. The results show that these genes evolve according to a birth-anddeath model under strong purifying selection, thereby explaining how dive ...
... unclear. Therefore, the aim of this study was to investigate what processes underlie the long-term evolution of apicomplexan 18S genes in representative species. The results show that these genes evolve according to a birth-anddeath model under strong purifying selection, thereby explaining how dive ...
Microarray data normalization and data transformation
... • Although this may not produce any significant changes in relative expression levels between conditions for highly expressed genes, it can have profound effect on estimates for genes expressed at low to moderate levels (2) Chooses to subtract background – To use the fluorescence of the area surroun ...
... • Although this may not produce any significant changes in relative expression levels between conditions for highly expressed genes, it can have profound effect on estimates for genes expressed at low to moderate levels (2) Chooses to subtract background – To use the fluorescence of the area surroun ...
Induction of the white egg3 mutant phenotype by injection of the
... eggs. This effect was sequence specific because injection of GFP dsRNA did not reduce endogenous Bmwh3 mRNA. Sequence-specific silencing was also shown for GFP expression by interfering with the transient expression of GFP from a plasmid without affecting the colour of the eggs and larvae. This is t ...
... eggs. This effect was sequence specific because injection of GFP dsRNA did not reduce endogenous Bmwh3 mRNA. Sequence-specific silencing was also shown for GFP expression by interfering with the transient expression of GFP from a plasmid without affecting the colour of the eggs and larvae. This is t ...
The riboswitch control of bacterial metabolism
... become clear that nature has already devised its own aptamers that play important regulatory roles. RNA sensors have been discovered in both Gram-positive and Gram-negative bacteria that function as molecular switches in response to direct binding of structurally diverse metabolites. These natural R ...
... become clear that nature has already devised its own aptamers that play important regulatory roles. RNA sensors have been discovered in both Gram-positive and Gram-negative bacteria that function as molecular switches in response to direct binding of structurally diverse metabolites. These natural R ...
The Schistosoma gene discovery program: state of the art
... [http://www.ncbi.nlm.nih.gov/dbEST/index.html]. Cluster analyses of 8193 S. mansoni sequences and 891 S. japonicum sequences (these include ESTs and gene sequences) were performed by D Johnston (the SGN Secretary) using the Sequencher 3.1.1 software in 03/ 03/1999. The program was set to assemble se ...
... [http://www.ncbi.nlm.nih.gov/dbEST/index.html]. Cluster analyses of 8193 S. mansoni sequences and 891 S. japonicum sequences (these include ESTs and gene sequences) were performed by D Johnston (the SGN Secretary) using the Sequencher 3.1.1 software in 03/ 03/1999. The program was set to assemble se ...
Problem set questions from Exam 3 – Eukaryotic Gene Regulation
... You have discovered a gene in yeast that is involved in repairing damaged DNA. Mutations in this gene make yeast more sensitive to DNA-damaging agents such as UV radiation. You designate your new gene Rad66. To study the regulation of Rad66, you fuse the cis regulatory region upstream of the Rad66 o ...
... You have discovered a gene in yeast that is involved in repairing damaged DNA. Mutations in this gene make yeast more sensitive to DNA-damaging agents such as UV radiation. You designate your new gene Rad66. To study the regulation of Rad66, you fuse the cis regulatory region upstream of the Rad66 o ...
Nucleotide sequence changes in the MSX1 and IRF6 genes in
... malformations in humans. It is a complex multifactorial trait with a considerable genetic component. Among numerous candidate genes, those related to syndromic OFC recently have emerged as particularly strong ones. Our study was aimed to investigate whether mutations in the MSX1 and IRF6 genes contr ...
... malformations in humans. It is a complex multifactorial trait with a considerable genetic component. Among numerous candidate genes, those related to syndromic OFC recently have emerged as particularly strong ones. Our study was aimed to investigate whether mutations in the MSX1 and IRF6 genes contr ...
Effects of rumen-protected choline on performance and hepatic fat
... The effects of rumen-protected choline (RPC) on feed intake, milk yield, milk composition and hepatic fat metabolism were evaluated in periparturient dairy cows. Multiparous cows (38) were blocked in pairs. Cows within each block were assigned at random to either RPC (60 g RPC/day; ReaShure, Balchem ...
... The effects of rumen-protected choline (RPC) on feed intake, milk yield, milk composition and hepatic fat metabolism were evaluated in periparturient dairy cows. Multiparous cows (38) were blocked in pairs. Cows within each block were assigned at random to either RPC (60 g RPC/day; ReaShure, Balchem ...
Real time PCR based determination of gene copy numbers in
... Pichia pastoris is a prefered host for heterologous protein production. Expression cassettes are usually integrated into the genome of this methylotrophic yeast. This manuscript describes a method for fast and reliable gene copy number determinations for P. pastoris expression strains. We believe th ...
... Pichia pastoris is a prefered host for heterologous protein production. Expression cassettes are usually integrated into the genome of this methylotrophic yeast. This manuscript describes a method for fast and reliable gene copy number determinations for P. pastoris expression strains. We believe th ...
the complete Genetics Booklet
... Ichthyosis genes to pass on, that's true. But like any other parent, he will contribute only one half of his children's genes, and his child would need two “b”genes to display the disorder. That child could get another “b” gene only if his other parent were a carrier for that same disorder. Since La ...
... Ichthyosis genes to pass on, that's true. But like any other parent, he will contribute only one half of his children's genes, and his child would need two “b”genes to display the disorder. That child could get another “b” gene only if his other parent were a carrier for that same disorder. Since La ...
Beads on a string Bowater Biochem Soc Trans 2012
... for the interaction of ISW1 on a unit of two nucleosome particles and showed how ISW1 could set the spacing between adjacent nucleosomes. The data from the Richmond laboratory provide support for ATP-dependent remodelling factors as the important driver of nucleosome positioning. The location of nuc ...
... for the interaction of ISW1 on a unit of two nucleosome particles and showed how ISW1 could set the spacing between adjacent nucleosomes. The data from the Richmond laboratory provide support for ATP-dependent remodelling factors as the important driver of nucleosome positioning. The location of nuc ...
this PDF file - Trends in Pharmaceutical Sciences
... that pal is originated in the ancestor of land plants or in the ancestor of fungi, then it had been transferred via HGT between these two phyla (32). It's reported that gymnosperm pal genes have been clustered into three clades (12). Bagal's study shows that the origin of the most ancient clade is e ...
... that pal is originated in the ancestor of land plants or in the ancestor of fungi, then it had been transferred via HGT between these two phyla (32). It's reported that gymnosperm pal genes have been clustered into three clades (12). Bagal's study shows that the origin of the most ancient clade is e ...
Full Text - Gene, Cell and Tissue
... Figure 2. The Results of HahI Digestion for the Detection of p.R390H ...
... Figure 2. The Results of HahI Digestion for the Detection of p.R390H ...
Genetic determinism in the Finnish upper secondary school biology
... mostly about how much genes determine and how the understanding of the role of genes is best learnt. This debate shows how important genetics is for both understanding what being human means and how many connections it has to social and cultural issues. Many different concepts from eugenics and immo ...
... mostly about how much genes determine and how the understanding of the role of genes is best learnt. This debate shows how important genetics is for both understanding what being human means and how many connections it has to social and cultural issues. Many different concepts from eugenics and immo ...