How Biologists Conceptualize Genes: An empirical study
... and splicing the primary mRNA transcript in alternative ways. One response to introns is to use the abovementioned strategy of retaining a unitary function for each gene by moving the function closer to the DNA itself. If a gene is defined as the stretch of DNA coding for a single primary mRNA trans ...
... and splicing the primary mRNA transcript in alternative ways. One response to introns is to use the abovementioned strategy of retaining a unitary function for each gene by moving the function closer to the DNA itself. If a gene is defined as the stretch of DNA coding for a single primary mRNA trans ...
Elucidating the Role of Gonadal Hormones in Sexually
... We now report analyses of the molecular basis of these sex differences and of the effects of sex on gene expression networks. We analyzed liver gene expression of hormone-treated gonadectomized mice as well as XX male and XY female mice. Differences in gene expression resulted in large part from acu ...
... We now report analyses of the molecular basis of these sex differences and of the effects of sex on gene expression networks. We analyzed liver gene expression of hormone-treated gonadectomized mice as well as XX male and XY female mice. Differences in gene expression resulted in large part from acu ...
Analysis of GNAZ Gene Polymorphism in Bipolar Affective Disorder
... and ␥ G-protein subunits have been identified. The capacity of G-protein subunits to mix and match components and couple to different neurotransmitter receptors, thereby providing the opportunity for a single defective subunit protein to interact with multiple neurotransmitter/signal transduction pa ...
... and ␥ G-protein subunits have been identified. The capacity of G-protein subunits to mix and match components and couple to different neurotransmitter receptors, thereby providing the opportunity for a single defective subunit protein to interact with multiple neurotransmitter/signal transduction pa ...
A catalogue of imprinted genes and parent-of
... reported (2–4). Since this time, numerous genes have been shown to be subject to genomic imprinting, a process through which the expression of a gene is dependent on the sex of the parent from which it was inherited. Additionally, we now recognize several phenotypes in humans, mice and other animals ...
... reported (2–4). Since this time, numerous genes have been shown to be subject to genomic imprinting, a process through which the expression of a gene is dependent on the sex of the parent from which it was inherited. Additionally, we now recognize several phenotypes in humans, mice and other animals ...
Galaxy Basics: DataSet Manipulation inside of Galaxy
... Note, the schema does not show the data in the same order as you see it in the BED file format. ...
... Note, the schema does not show the data in the same order as you see it in the BED file format. ...
Differential Gene Expression in the Siphonophore
... Both the Helicos and SOLiD sample preparation protocols are tag based – a single read is generated from a particular region of each sequenced mRNA molecule. In the case of Helicos Digital Gene Expression (DGE), the protocol is designed to generate a single read at the 59 end of each sequenced transc ...
... Both the Helicos and SOLiD sample preparation protocols are tag based – a single read is generated from a particular region of each sequenced mRNA molecule. In the case of Helicos Digital Gene Expression (DGE), the protocol is designed to generate a single read at the 59 end of each sequenced transc ...
Microarrays - Consortium for Mathematics and its Applications
... You are a practicing family doctor. A patient that you have had for many years, Ralph, comes to you for his yearly exam. During his physical, you notice that a mole on his back has changed in its appearance and size. It is no longer symmetrical and has developed an irregular, ragged border with the ...
... You are a practicing family doctor. A patient that you have had for many years, Ralph, comes to you for his yearly exam. During his physical, you notice that a mole on his back has changed in its appearance and size. It is no longer symmetrical and has developed an irregular, ragged border with the ...
Genome-Wide Gene Expression Effects of Sex Chromosome
... (Figure 1). We chose this approach rather than screening progeny for exceptional karyotypes resulting from nondisjunction, because it allowed careful control of the larval environment while simultaneously producing a large number of adult flies that allowed well-replicated microarray analysis. All th ...
... (Figure 1). We chose this approach rather than screening progeny for exceptional karyotypes resulting from nondisjunction, because it allowed careful control of the larval environment while simultaneously producing a large number of adult flies that allowed well-replicated microarray analysis. All th ...
Sex Chromosome Dosage Effects On Gene Expression In
... expression data for 19,984 autosomal and 894 sex-chromosome genes using the Illumina oligonucleotide Beadarray platform (Methods), and (ii) an independent set of validation/replication samples from 401 participants (3 XO, 145 XX, 22 XXX, 146 XY, 34 XXY, 16 XYY, 17 XXYY, 8 XXXY, 10 XXXXY) with quanti ...
... expression data for 19,984 autosomal and 894 sex-chromosome genes using the Illumina oligonucleotide Beadarray platform (Methods), and (ii) an independent set of validation/replication samples from 401 participants (3 XO, 145 XX, 22 XXX, 146 XY, 34 XXY, 16 XYY, 17 XXYY, 8 XXXY, 10 XXXXY) with quanti ...
Missense mutations in the PAX6 gene in aniridia.
... vertebrates since paired originally was identified as a segmentation gene in Drosophila melanogaster.1-2 The encoded proteins are transcriptional regulators with DNA binding through a conserved domain consisting of 128 amino acids (paired box).3 Some Pax genes share another conserved domain, homeobo ...
... vertebrates since paired originally was identified as a segmentation gene in Drosophila melanogaster.1-2 The encoded proteins are transcriptional regulators with DNA binding through a conserved domain consisting of 128 amino acids (paired box).3 Some Pax genes share another conserved domain, homeobo ...
Polling in Cattle - South Devon Herd Book Society
... An added complication when breeding for polling is the issue of scurring which can occur. Scurs are small growths of material very similar to horns that can develop in polled cattle. Traditionally it has been believed that scurs are sex-influenced due to the fact that they have been shown to be more ...
... An added complication when breeding for polling is the issue of scurring which can occur. Scurs are small growths of material very similar to horns that can develop in polled cattle. Traditionally it has been believed that scurs are sex-influenced due to the fact that they have been shown to be more ...
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... expression data for 19,984 autosomal and 894 sex-chromosome genes using the Illumina oligonucleotide Beadarray platform (Methods), and (ii) an independent set of validation/replication samples from 401 participants (3 XO, 145 XX, 22 XXX, 146 XY, 34 XXY, 16 XYY, 17 XXYY, 8 XXXY, 10 XXXXY) with quanti ...
... expression data for 19,984 autosomal and 894 sex-chromosome genes using the Illumina oligonucleotide Beadarray platform (Methods), and (ii) an independent set of validation/replication samples from 401 participants (3 XO, 145 XX, 22 XXX, 146 XY, 34 XXY, 16 XYY, 17 XXYY, 8 XXXY, 10 XXXXY) with quanti ...
Missense mutations in the PAX6 gene in aniridia.
... vertebrates since paired originally was identified as a segmentation gene in Drosophila melanogaster.1-2 The encoded proteins are transcriptional regulators with DNA binding through a conserved domain consisting of 128 amino acids (paired box).3 Some Pax genes share another conserved domain, homeobo ...
... vertebrates since paired originally was identified as a segmentation gene in Drosophila melanogaster.1-2 The encoded proteins are transcriptional regulators with DNA binding through a conserved domain consisting of 128 amino acids (paired box).3 Some Pax genes share another conserved domain, homeobo ...
Interacting Gene Clusters and the Evolution of the Vertebrate
... Interacting Gene Clusters and the Evolution of the Vertebrate Immune System Takashi Makino and Aoife McLysaght Smurfit Institute of Genetics, University of Dublin, Trinity College, Dublin, Ireland Unraveling the ‘‘code’’ of genome structure is an important goal of genomics research. Colocalization o ...
... Interacting Gene Clusters and the Evolution of the Vertebrate Immune System Takashi Makino and Aoife McLysaght Smurfit Institute of Genetics, University of Dublin, Trinity College, Dublin, Ireland Unraveling the ‘‘code’’ of genome structure is an important goal of genomics research. Colocalization o ...
INTRODUCTION
... - Increase in number (expansion) of trinucleotide repetitions. Mutations that cause genetic diseases, may involve structural, transport and embryonic proteins, enzymes. Levels of protein synthesis regulation: - Pretranscriptional. - Transcriptional. - Translational. We can assume that at all of thes ...
... - Increase in number (expansion) of trinucleotide repetitions. Mutations that cause genetic diseases, may involve structural, transport and embryonic proteins, enzymes. Levels of protein synthesis regulation: - Pretranscriptional. - Transcriptional. - Translational. We can assume that at all of thes ...
Down Syndrome Research and Practice Volume 5 Issue 3 Pages
... sequencing in a donor of extra chromosome 21. Three new point, nonpolymorphic mutations, not described before, were found in the following genes:- ATP-ase, G8764A and ND-5 G13243A with the same amino-acid substitutions Ala/Thr and in ND-1 G3337A-Val/Met. The mtDNA mutations detected in cases of Alzh ...
... sequencing in a donor of extra chromosome 21. Three new point, nonpolymorphic mutations, not described before, were found in the following genes:- ATP-ase, G8764A and ND-5 G13243A with the same amino-acid substitutions Ala/Thr and in ND-1 G3337A-Val/Met. The mtDNA mutations detected in cases of Alzh ...
A Molecular Genetic Study of Factor XI Deficiency
... High molecular weight genomic DNA was extracted from peripheral blood leukocytes. DNA (200 ng) was used in a polymerase chain reaction (PCR) of 40 cycles with 100 pmol of each oligonucleotide primer following the method of Saiki et a1.16 The primers for the type I analysis were 5’-AGTGACCAACGAAGAGTG ...
... High molecular weight genomic DNA was extracted from peripheral blood leukocytes. DNA (200 ng) was used in a polymerase chain reaction (PCR) of 40 cycles with 100 pmol of each oligonucleotide primer following the method of Saiki et a1.16 The primers for the type I analysis were 5’-AGTGACCAACGAAGAGTG ...
A receptor like kinase gene with expressional responsiveness on
... Previous reports have shown that the genes, OsKS4(LOC_Os04g10060) and Os04g10010(LOC_Os04g10010), function as marker genes involved for the downstream responses associated PTI (Park et al. 2012; Chen et al. 2014a). Thus, we asked whether these two genes in Xa21 plants are also responsive to Xoo. For ...
... Previous reports have shown that the genes, OsKS4(LOC_Os04g10060) and Os04g10010(LOC_Os04g10010), function as marker genes involved for the downstream responses associated PTI (Park et al. 2012; Chen et al. 2014a). Thus, we asked whether these two genes in Xa21 plants are also responsive to Xoo. For ...
by ODRIOZOLA
... an intensely black tip, a sub-apical band of yellow, and below that a dull black base. The ventral areas of the coat are lighter, often lacking the black hair tips, resulting in a whitish yellow belly color and tail white underneath as in the cotton-tail rabbit. This is a very effective concealing p ...
... an intensely black tip, a sub-apical band of yellow, and below that a dull black base. The ventral areas of the coat are lighter, often lacking the black hair tips, resulting in a whitish yellow belly color and tail white underneath as in the cotton-tail rabbit. This is a very effective concealing p ...
Regulation of 6sg expression site transcription and switching in
... promoter manipulations at 6sg expression sites (ES) and examination of the behavior of ES promoters in ectopic locations both within the ES and at other loci. In summary, ES promoter sequences inserted into non-transcribed rRNA spacers are generally inactive, or have low activity, in bloodstream and ...
... promoter manipulations at 6sg expression sites (ES) and examination of the behavior of ES promoters in ectopic locations both within the ES and at other loci. In summary, ES promoter sequences inserted into non-transcribed rRNA spacers are generally inactive, or have low activity, in bloodstream and ...
Generating Marker-Free Transgenic Wheat Using Minimal Gene
... laborious and time consuming because of the several selection steps in progeny generations. In addition, the co-integration of the selection gene and GOI into the same locus makes the selective elimination unfeasible. Another option for marker gene elimination is the transposon mediated removal, whi ...
... laborious and time consuming because of the several selection steps in progeny generations. In addition, the co-integration of the selection gene and GOI into the same locus makes the selective elimination unfeasible. Another option for marker gene elimination is the transposon mediated removal, whi ...
Clinical Implications of
... cysteinemia causes atherosclerosis and thrombosis are not clear, endothelial dysfunction, damage to endothelial cells, and inflammation in the blood vessels caused by reactive oxygen species, including superoxide, are thought to be responsible for these diseases [11]. A number of factors cause hyper ...
... cysteinemia causes atherosclerosis and thrombosis are not clear, endothelial dysfunction, damage to endothelial cells, and inflammation in the blood vessels caused by reactive oxygen species, including superoxide, are thought to be responsible for these diseases [11]. A number of factors cause hyper ...
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... The transgenic mouse lines with mouse prosaposin promoter deletion constructs were 234Luc, 310Luc, 2400Luc, and 2400DLuc (Fig 1A). The tissue specific expression pattern of promoter deletion constructs was reported previously (Sun et al., 2000). The expression pattern for each construct was same amo ...
... The transgenic mouse lines with mouse prosaposin promoter deletion constructs were 234Luc, 310Luc, 2400Luc, and 2400DLuc (Fig 1A). The tissue specific expression pattern of promoter deletion constructs was reported previously (Sun et al., 2000). The expression pattern for each construct was same amo ...
Human Apolipoprotein A-l-C-lll Gene Complex is Located on
... the apo A-l-apo C-lll gene complex to chromosome 11 raises the interesting question as to whether the other apolipoprotein genes are also located in this region of the genome. Although mapping with DNA probes has not been done for the other apolipoprotein genes, there is some evidence from linkage a ...
... the apo A-l-apo C-lll gene complex to chromosome 11 raises the interesting question as to whether the other apolipoprotein genes are also located in this region of the genome. Although mapping with DNA probes has not been done for the other apolipoprotein genes, there is some evidence from linkage a ...