ATP16 Genes and Neighboring ORFs Are Duplicated on
... (8.4 and 30.4 kb) were hybridized with the ATP16 probe. According to the data of the Genome Project, the long DNA band (30.4 kb) was expected from S288C but not the short band (8.4 kb). This showed that one extra SphI site, which had not been reported by the Genome Project, should be present between ...
... (8.4 and 30.4 kb) were hybridized with the ATP16 probe. According to the data of the Genome Project, the long DNA band (30.4 kb) was expected from S288C but not the short band (8.4 kb). This showed that one extra SphI site, which had not been reported by the Genome Project, should be present between ...
Solid Tumour Section Soft Tissue Tumors: Liposarcoma: Myxoid liposarcoma
... of the fusion protein in tumor cells. The transforming properties of the FUS-DDIT3 fusion protein have been demonstrated in NIH 3T3 cells and fibroblasts. In the FUS-DDIT3 fusion, transcriptional activation is specifically conferred on the chimeric protein by the FUS segment after the translocation ...
... of the fusion protein in tumor cells. The transforming properties of the FUS-DDIT3 fusion protein have been demonstrated in NIH 3T3 cells and fibroblasts. In the FUS-DDIT3 fusion, transcriptional activation is specifically conferred on the chimeric protein by the FUS segment after the translocation ...
LP - Columbia University
... a. Why can't you just add the missing protein? The protein usually gets broken down before it reaches its target cells. This is what usually happens; only a few proteins (mostly those that function in blood such as insulin and clotting factors) can be supplied from outside. b. Why Gene therapy. It s ...
... a. Why can't you just add the missing protein? The protein usually gets broken down before it reaches its target cells. This is what usually happens; only a few proteins (mostly those that function in blood such as insulin and clotting factors) can be supplied from outside. b. Why Gene therapy. It s ...
From QTLs for enzyme activity to candidate genes in maize
... tested using 65 RILs. The enzyme activities (SPS and AGP) and the carbohydrate contents (sucrose, glucose and fructose) were measured in the source (expanded third leaf ) and sink (base of growing fourth leaf ), in parallel with plant growth. In source leaves (Fig. 1), three QTLs were obtained for S ...
... tested using 65 RILs. The enzyme activities (SPS and AGP) and the carbohydrate contents (sucrose, glucose and fructose) were measured in the source (expanded third leaf ) and sink (base of growing fourth leaf ), in parallel with plant growth. In source leaves (Fig. 1), three QTLs were obtained for S ...
Association study of the estrogen receptor I gene (ESR1) in anorexia
... association between rs3798577 and EDs.7 Although the haplotype had a comparable frequency in our sample, it was not associated with either EDs, BN, AN, or restricting type AN. In addition, the frequency of none of the three ESR1 SNPs differed between the groups. Altogether, we could not confirm the ...
... association between rs3798577 and EDs.7 Although the haplotype had a comparable frequency in our sample, it was not associated with either EDs, BN, AN, or restricting type AN. In addition, the frequency of none of the three ESR1 SNPs differed between the groups. Altogether, we could not confirm the ...
Gene expression in early and progression phases of autosomal
... In addition, several genes differentially expressed in this model are components of three morphogenetic signaling pathways. Quantitative real time PCR was performed to validate gene expression changes identified by microarray analysis during disease progression (see Additional file 7 for details of ...
... In addition, several genes differentially expressed in this model are components of three morphogenetic signaling pathways. Quantitative real time PCR was performed to validate gene expression changes identified by microarray analysis during disease progression (see Additional file 7 for details of ...
Lecture#17 Page 1 BIOLOGY 207 – Dr McDermid Lecture#17
... 1. Gene loci on the same chromosome may show linkage, not independent assortment. 2. Most linkage between gene loci is not complete because crossing over between loci can occur during meiosis. 3. The extent of linkage between gene loci is expressed as the frequency of recombinant type progeny (vs. p ...
... 1. Gene loci on the same chromosome may show linkage, not independent assortment. 2. Most linkage between gene loci is not complete because crossing over between loci can occur during meiosis. 3. The extent of linkage between gene loci is expressed as the frequency of recombinant type progeny (vs. p ...
Saccharopolyspora erythraea that are involved
... After alteration, the gene and its surrounding DNA were transferred to plasmid pWHM3, an E . coli-Streptornyces shuttle plasmid that replicates poorly in Sac. erythraea. Homology-based, integrative transformation of Sac. erythraea protoplasts with the pWHM3 derivatives was then carried out as descri ...
... After alteration, the gene and its surrounding DNA were transferred to plasmid pWHM3, an E . coli-Streptornyces shuttle plasmid that replicates poorly in Sac. erythraea. Homology-based, integrative transformation of Sac. erythraea protoplasts with the pWHM3 derivatives was then carried out as descri ...
Chapter 14: Genotype, phenotype and crosses Key questions
... Twins have also been used to investigate the contribution of genes to behavioural traits such as personality, handedness and alcoholism. 17 Due to the absence of the enzyme phenylalanine hydroxylase, an accumulation of the amino acid phenylalanine in the tissues of individuals with phenylketonuria r ...
... Twins have also been used to investigate the contribution of genes to behavioural traits such as personality, handedness and alcoholism. 17 Due to the absence of the enzyme phenylalanine hydroxylase, an accumulation of the amino acid phenylalanine in the tissues of individuals with phenylketonuria r ...
development, the Linker histone H1 is essential for Drosophila
... functions of linker histones in vivo have used gene inactivation approaches. Elimination of the linker histone-like protein Hho1p in Saccharomyces cerevisiae did not cause any major phenotypic effects, nor were any perturbations in chromosome structure apparent (Ushinsky et al. 1997; Patterton et al ...
... functions of linker histones in vivo have used gene inactivation approaches. Elimination of the linker histone-like protein Hho1p in Saccharomyces cerevisiae did not cause any major phenotypic effects, nor were any perturbations in chromosome structure apparent (Ushinsky et al. 1997; Patterton et al ...
homolog of the agouti gene
... Department, Glaxo Research Institute, Research Triangle Park, NC 27709; and IDepartment of Pediatric Endocrinology, Eastern Carolina University, Greenville, NC 27858 Communicated by Liane B. Russell, May 31, 1994 ...
... Department, Glaxo Research Institute, Research Triangle Park, NC 27709; and IDepartment of Pediatric Endocrinology, Eastern Carolina University, Greenville, NC 27858 Communicated by Liane B. Russell, May 31, 1994 ...
Mendelian Genetics - hills
... Both the husband and the wife have normal vision. The wife gives birth to a colorblind daughter. Is it more likely the father had normal vision or was colorblind? What does this lead you to deduce about the girl’s parentage? What is the genotype of a colorblind male with long fingers is s=long finge ...
... Both the husband and the wife have normal vision. The wife gives birth to a colorblind daughter. Is it more likely the father had normal vision or was colorblind? What does this lead you to deduce about the girl’s parentage? What is the genotype of a colorblind male with long fingers is s=long finge ...
(C677T), FVL (G1691A) and ACE (I28005D)
... and genotypic variations, which correlate with specific phenotypes are sometimes associated with the development of human disease in different ethnic groups [5]. Polymorphisms of various genes encoding thrombophilic factors like Methylenetetrahydrofolate reductase (MTHFR; OMIM: 607093), Factor V Lei ...
... and genotypic variations, which correlate with specific phenotypes are sometimes associated with the development of human disease in different ethnic groups [5]. Polymorphisms of various genes encoding thrombophilic factors like Methylenetetrahydrofolate reductase (MTHFR; OMIM: 607093), Factor V Lei ...
Chapter 1 Gene targeting, principles,and practice in mammalian cells
... - marker gene may affect other gene expression. - may remove marker gene after targeting to avoid undesirable effects - marker gene removal can be readily accomplished by Cre-loxP system ...
... - marker gene may affect other gene expression. - may remove marker gene after targeting to avoid undesirable effects - marker gene removal can be readily accomplished by Cre-loxP system ...
Identification of the Minus-Dominance Gene Ortholog in
... RWP12 is located at the N terminus; the initial methionine is set at the seventh residue of the multiple alignment. Since it seemed likely that the RWP-RK domain should extend farther into the 59-region, the DNA sequence neighboring RWP12 was analyzed by GENSCAN (Burge and Karlin 1997) with the ‘‘or ...
... RWP12 is located at the N terminus; the initial methionine is set at the seventh residue of the multiple alignment. Since it seemed likely that the RWP-RK domain should extend farther into the 59-region, the DNA sequence neighboring RWP12 was analyzed by GENSCAN (Burge and Karlin 1997) with the ‘‘or ...
Genetic epidemiology of coronary artery disease: an Asian Indian
... IL6 gene in a subset of patients with age at onset under 45 years and that was shown to modulate plasma CRP and fibrinogen levels (Maitra et al. 2008). Patel et al. (2008) have commented that as there in general consences on early CAD onset in Asian Indian based on earlier reports, the findings Mait ...
... IL6 gene in a subset of patients with age at onset under 45 years and that was shown to modulate plasma CRP and fibrinogen levels (Maitra et al. 2008). Patel et al. (2008) have commented that as there in general consences on early CAD onset in Asian Indian based on earlier reports, the findings Mait ...
Slide set - Mediterranean Group for the Study of Diabetes
... • Application of SNPscore system yielded correlation coefficient (R2=0.9596) which reflects the significant influence of SNPscore on risk of pGDM phenotype. • The results of allele scoring approach were more likely a reflection of the ongoing pathophysiology of the pGDM. • The concept of allele scor ...
... • Application of SNPscore system yielded correlation coefficient (R2=0.9596) which reflects the significant influence of SNPscore on risk of pGDM phenotype. • The results of allele scoring approach were more likely a reflection of the ongoing pathophysiology of the pGDM. • The concept of allele scor ...
THE FAT YOU CAN`T SEE
... developed nations—the liver has lost its luster. It is swollen, yellowish, congested with fat, and doesn’t function up to par. Over time, this condition, called fatty liver disease, can lead to inflammation, scarring, and hardening of the organ, and eventually, liver failure. In some people, it caus ...
... developed nations—the liver has lost its luster. It is swollen, yellowish, congested with fat, and doesn’t function up to par. Over time, this condition, called fatty liver disease, can lead to inflammation, scarring, and hardening of the organ, and eventually, liver failure. In some people, it caus ...
gene (Pun1? - UC Davis Plant Sciences
... • Fruit weight QTL didn’t co-localize w/ capsaicinoid QTL • cap7.2 likely orthologous to major QTL previously identified • Digenic interaction may facilitate further genetic analysis ...
... • Fruit weight QTL didn’t co-localize w/ capsaicinoid QTL • cap7.2 likely orthologous to major QTL previously identified • Digenic interaction may facilitate further genetic analysis ...
Fall 2012 HHMI Bulletin: The Fat You Can`t See
... developed nations—the liver has lost its luster. It is swollen, yellowish, congested with fat, and doesn’t function up to par. Over time, this condition, called fatty liver disease, can lead to inflammation, scarring, and hardening of the organ, and eventually, liver failure. In some people, it caus ...
... developed nations—the liver has lost its luster. It is swollen, yellowish, congested with fat, and doesn’t function up to par. Over time, this condition, called fatty liver disease, can lead to inflammation, scarring, and hardening of the organ, and eventually, liver failure. In some people, it caus ...
Limitations of Pseudogenes in Identifying Gene Losses
... the v5.3 genome assembly and annotation to determine if any of these potential gene losses are simply due to gaps in the v4.3 assembly. The 114 query sequences were searched against the v5.3 D. melanogaster genome using BLASTn with the same criteria as before. Interestingly, 23 query genes hit very ...
... the v5.3 genome assembly and annotation to determine if any of these potential gene losses are simply due to gaps in the v4.3 assembly. The 114 query sequences were searched against the v5.3 D. melanogaster genome using BLASTn with the same criteria as before. Interestingly, 23 query genes hit very ...
appendix 1 – simple nomenclature
... different if we compare different alleles of a gene and they may behave differently – often one protein will “work better” than the other. If the promoter of a “functional” al ...
... different if we compare different alleles of a gene and they may behave differently – often one protein will “work better” than the other. If the promoter of a “functional” al ...
Inferring Ancestral Chloroplast Genomes with Inverted
... derived early in the chloroplast endosymbiosis [21]. Although the sequenced cyanobacteria Nostoc and Synechococcus do not maintain rrn-containing IRs, if other cyanobacteria are identified with structures similar to the chloroplast IR, then it would suggest an even earlier origin for this structure. ...
... derived early in the chloroplast endosymbiosis [21]. Although the sequenced cyanobacteria Nostoc and Synechococcus do not maintain rrn-containing IRs, if other cyanobacteria are identified with structures similar to the chloroplast IR, then it would suggest an even earlier origin for this structure. ...
Gene Section ERG (v-ets erythroblastosis virus E26 oncogene like (avian))
... endothelial cells. In the GNF SymAtlas database, the major ERG expression was found to be in CD34+ cells (that include both hematopoietic stem cells and endothelial cells). ERG was also reported to be expressed in during early T and B cell development, and to be down-regulated in later stages of B a ...
... endothelial cells. In the GNF SymAtlas database, the major ERG expression was found to be in CD34+ cells (that include both hematopoietic stem cells and endothelial cells). ERG was also reported to be expressed in during early T and B cell development, and to be down-regulated in later stages of B a ...
Role of Cryptic Genes in Microbial Evolution1
... four vitamins at frequencies expected for single-step mutations. Similar results were obtained with a strain of L. acidophilus, indicating the generality of the phenomenon. The nature of the mutations is unknown, but their existence makes it clear that the original auxotrophy did not result from mul ...
... four vitamins at frequencies expected for single-step mutations. Similar results were obtained with a strain of L. acidophilus, indicating the generality of the phenomenon. The nature of the mutations is unknown, but their existence makes it clear that the original auxotrophy did not result from mul ...