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The Operon - dl.edi
The Operon - dl.edi

... The gene encoding the lac repressor is called the I gene. It happens to be located just upstream of the lac promoter. However, its precise location is probably not important because it achieves its effect by means of its protein product, which is free to diffuse throughout the cell. And, in fact, th ...
The complete nucleotide sequence of apple mosaic virus (ApMV
The complete nucleotide sequence of apple mosaic virus (ApMV

... or coat protein is added. This function can be fulfilled by RNA 4 or coat protein of heterologous as well as homologous viruses of these genera, but not from other genera (Gonsalves & Fulton, 1977). Biological and chemical RNA protection assays show that both the AMV and ilarvirus 3h non-translated ...
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here - IMSS Biology 2014

... All this information, all of an organism’s DNA, is called the genome. A genome is sort of like a recipe book – it has all the instructions to make all different sorts of proteins, just like recipes have instructions to make many types of meals. But how does that information get translated to protein ...
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Chapter 2

... •Mutations in these regions have mild and severe effects on transcription. ...
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... Expression: When? (Elowitz and Leibler) ...
Antisense Oligonucleotides: Strategies and Applications
Antisense Oligonucleotides: Strategies and Applications

A different PowerPoint that combines the
A different PowerPoint that combines the

... • There are 20 amino acids, but 64 possible codons • So each amino acid may have more than one codon that codes for it. ...
Long noncoding RNAs and human disease - e
Long noncoding RNAs and human disease - e

... been implicated in gene-regulatory roles, such as chromosome dosage-compensation, imprinting, epigenetic regulation, cell cycle control, nuclear and cytoplasmic trafficking, transcription, translation, splicing, cell differentiation, and others [3,11–14]. It is now becoming evident that ncRNAs are i ...
RNA Structure
RNA Structure

... ii. RNA – there are 4 different types and they serve different purposes 1. The first one is the focus of our lecture, which is called messenger RNA or mRNA. 2. The second one is called ribosomal RNA or rRNA. 3. The third one is transfer RNA or tRNA. 4. In addition to these RNA there are small nuclea ...
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Computational Biology - Bioinformatik
Computational Biology - Bioinformatik

... Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of - double-stranded RNA molecules, - that are 20-25 nucleotides in length (often precisely 21 nt) and play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNA ...
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DNA replication

... mobilome, since they are often associated with conjugation, a mechanism of horizontal gene transfer. ...
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ELSI Learning Objective

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What do genes do? - The Open University
What do genes do? - The Open University

... One important property of DNA is that it carries genetic information in the simple coding language of just four bases. These bases, which can be arranged in a huge variety of sequences, represent a vast potential store of information. In this course, we consider how this information is used by the c ...
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RNA Processing: Eukaryotic mRNAs

Objectives - World of Teaching
Objectives - World of Teaching

... • The Lac Operon is an example of an operon that is able to regulate itself depending on the environmental conditions it is subjected to. • It codes for 3 genes: Beta-galactosidase, lactose permease and Thiogalactosidase transacetylase. These genes are involved in lactose metabolism. • If lactose is ...
MODULE 1 The Central Dogma Objective 1.4 LESSON A
MODULE 1 The Central Dogma Objective 1.4 LESSON A

... 2. After students have successfully reviewed these topics hand out the Altered Gene Expression Assignment and instruct them to find an article that refers to an organism that exhibits altered gene expression. Altered gene expression could be a mutated gene, a gene that was inserted into an organism, ...
Figure 19.5 A eukaryotic gene and its transcript
Figure 19.5 A eukaryotic gene and its transcript

... Translation ...
No evidence for viral sequences in lepidic
No evidence for viral sequences in lepidic

... and with sequences of Uniprot database using BLASTX with an E-value equal to 1E-3. All ...
Treatment of Viruses
Treatment of Viruses

... Lots of variations on the viral life cycle Viruses can replicate in the nucleus or the cytoplasm of the host cell Some viruses (Herpes simplex 1, 2; Polio virus) replicate inside nerve cells only ...
Have a go at our V(D)J recombination jigsaw game. How many
Have a go at our V(D)J recombination jigsaw game. How many

... where antigen-recognition and binding takes place. A single pathogen can have many different antigens, for each there may be many antibodies. Our immune system has the potential to produce 10 billion different antibodies, even before it meets an invader! This diversity ensures our immune system can ...
BIOL 105 S 2013 Practice Quiz Supp DNA
BIOL 105 S 2013 Practice Quiz Supp DNA

... Which of the following tasks is not accomplished by DNA? A) undergoes mutations that can provide variation B) provides energy for the cell C) stores information D) replicates to pass a copy to the next generation Answer B Which of the following statements is incorrect concerning deoxyribonucleic aci ...
Investigating regulation of aging by transcription factors DAF 16 and
Investigating regulation of aging by transcription factors DAF 16 and

... experiment using the aforementioned methods, which involve using RNA interference methods to silence certain genes. Through this, we can gain insight into whether the two transcription factors regulate each other and or affect the ability to increase lifespan. The hypothesis of this experiment was t ...
Chapter 7: Microbial Genetics 10/8/2015
Chapter 7: Microbial Genetics 10/8/2015

... Chapter Reading – pp. 197-198, 201-205 ...
< 1 ... 81 82 83 84 85 86 87 88 89 ... 225 >

RNA silencing

RNA silencing (associated with the concept of post-transcriptional gene silencing or RNA interference) refers to a family of gene silencing effects by which the expression of one or more genes is downregulated or entirely suppressed by non-coding RNAs, particularly small RNAs. It may also refer to the introduction of a synthetic antisense RNA molecule used in scientific experiments on gene expression. RNA silencing may also be defined as sequence-specific regulation of gene expression triggered by double-stranded RNA (dsRNA). RNA silencing mechanisms are highly conserved in most eukaryotes. The most common and well-studied example is RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the degradation of complementary messenger RNA. Other classes of small RNA have been identified, including piwi-interacting RNA (piRNA) and its subspecies repeat associated small interfering RNA (rasiRNA).
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