Molecular diversity through RNA editing: a balancing act
... RNA editing is broadly defined as the post-transcriptional alteration of RNA sequences through the insertion, deletion or modification of nucleotides but not including RNA processing events such as splicing, polyadenylation or the degradation of RNA molecules [1]. Of the various types of RNA editing ...
... RNA editing is broadly defined as the post-transcriptional alteration of RNA sequences through the insertion, deletion or modification of nucleotides but not including RNA processing events such as splicing, polyadenylation or the degradation of RNA molecules [1]. Of the various types of RNA editing ...
PDF - Blood Journal
... was discovered in 1991.6 This lncRNA and a handful of others were considered to be relatively infrequent until large-scale transcriptome sequencing identified thousands more.2 Now, candidate lncRNAs are recognized by computational algorithms that identify transcripts without protein coding potential, ...
... was discovered in 1991.6 This lncRNA and a handful of others were considered to be relatively infrequent until large-scale transcriptome sequencing identified thousands more.2 Now, candidate lncRNAs are recognized by computational algorithms that identify transcripts without protein coding potential, ...
Lac
... But there’s more… If glucose is available, the cell would rather use that than lactose =========== lacL ======ZYA======== ...
... But there’s more… If glucose is available, the cell would rather use that than lactose =========== lacL ======ZYA======== ...
Modulation of CTCF Insulator Function by
... genes, including regulation of enhancerpromoter interactions, imprinting, inhibition of nucleolar transcription, and coactivation of unlinked genes (Wallace and Felsenfeld, 2007). These diverse functions are in part mediated by the ability of CTCF to stabilize long-range chromatin contacts and organ ...
... genes, including regulation of enhancerpromoter interactions, imprinting, inhibition of nucleolar transcription, and coactivation of unlinked genes (Wallace and Felsenfeld, 2007). These diverse functions are in part mediated by the ability of CTCF to stabilize long-range chromatin contacts and organ ...
Phylogenetic, amino acid content and indel analyses
... sequences encoding conserved amino acid sequences in the rpoB genes of Mycobacterium tuberculosis (EMBL accession no. U12205), Mycobacterium leprae (Z14314), Mycobacterium smegmatis (U24494), Bacillus subtilis (L24376) and Staphylococcus aureus (X64172) and the rplL genes of Escherichia coli (V00339 ...
... sequences encoding conserved amino acid sequences in the rpoB genes of Mycobacterium tuberculosis (EMBL accession no. U12205), Mycobacterium leprae (Z14314), Mycobacterium smegmatis (U24494), Bacillus subtilis (L24376) and Staphylococcus aureus (X64172) and the rplL genes of Escherichia coli (V00339 ...
the function and synthesis of ribosomes
... by the long extensions of four r-proteins, but these are too far away to participate directly in catalysis. From this, it was concluded that the peptidyl-transfer reaction is catalysed by RNA1,20. On the basis of the structure of the 50S subunit in complex with analogues that mimic the substrates fo ...
... by the long extensions of four r-proteins, but these are too far away to participate directly in catalysis. From this, it was concluded that the peptidyl-transfer reaction is catalysed by RNA1,20. On the basis of the structure of the 50S subunit in complex with analogues that mimic the substrates fo ...
Restriction fragment differential display of pediocin
... of coding genomic sequences (Fislage et al., 1997) and many random primers are required to cover the whole bacterial genome. We have developed the so-called restriction fragment differential display PCR (RFDD-PCR) which is a variation of the cDNA amplified fragment length polymorphism DD technique o ...
... of coding genomic sequences (Fislage et al., 1997) and many random primers are required to cover the whole bacterial genome. We have developed the so-called restriction fragment differential display PCR (RFDD-PCR) which is a variation of the cDNA amplified fragment length polymorphism DD technique o ...
How does the cell regulate arsenate respiration and
... What are the sensitivities of arrA and arsC expression to As? ...
... What are the sensitivities of arrA and arsC expression to As? ...
The E-Class PPR Protein MEF3 of Arabidopsis
... RT–PCR, reverse transcription–PCR; SNP, single nucleotide polymorphism. ...
... RT–PCR, reverse transcription–PCR; SNP, single nucleotide polymorphism. ...
Posttranscriptional Control of Chloroplast Gene Expression
... nucleotide modification, is one of the most striking chloroplast oddities and also occurs in plant mitochondria. Chloroplast RNA editing involves mostly cytidine-to-uridine conversions with the reverse change occurring only in few cases (3). It thus adds a novel posttranscriptional step in chloropla ...
... nucleotide modification, is one of the most striking chloroplast oddities and also occurs in plant mitochondria. Chloroplast RNA editing involves mostly cytidine-to-uridine conversions with the reverse change occurring only in few cases (3). It thus adds a novel posttranscriptional step in chloropla ...
Fulltext PDF - Indian Academy of Sciences
... into 27-nt long RNAs. These are called piRNAs, on account of their ability to complex with the piwi protein, Otiwi1. The complex of piRNA × Otiwi1 marks the MDSs complementary to piRNA. Thereby, the MDSs are shielded against any nuclease attack. On the other hand, long telomere bearing RNA serves as ...
... into 27-nt long RNAs. These are called piRNAs, on account of their ability to complex with the piwi protein, Otiwi1. The complex of piRNA × Otiwi1 marks the MDSs complementary to piRNA. Thereby, the MDSs are shielded against any nuclease attack. On the other hand, long telomere bearing RNA serves as ...
Antisense derivatives of U7 small nuclear RNA as
... where splicing occurs (see chapter 42 Aartsma Rus). This is why derivatives of U small nuclear RNAs (snRNAs), and in particular of U7 snRNA, have been widely used for this purpose [1]. Apart from the advantage that the antisense RNA accumulates as part of a stable small nuclear ribonucleoprotein (sn ...
... where splicing occurs (see chapter 42 Aartsma Rus). This is why derivatives of U small nuclear RNAs (snRNAs), and in particular of U7 snRNA, have been widely used for this purpose [1]. Apart from the advantage that the antisense RNA accumulates as part of a stable small nuclear ribonucleoprotein (sn ...
Controlling morpholino experiments: don`t stop making antisense
... for antisense technologies for the study of animal development, focussing on controls for MO experiments, and we make recommendations about the use of these controls in zebrafish and frog embryos. These issues have been discussed elsewhere for RNAi experiments in the fruit fly Drosophila melanogaste ...
... for antisense technologies for the study of animal development, focussing on controls for MO experiments, and we make recommendations about the use of these controls in zebrafish and frog embryos. These issues have been discussed elsewhere for RNAi experiments in the fruit fly Drosophila melanogaste ...
PSI- Genes
... Cells have to reproduce many times. In complex organisms, trillions of copies are made from one original cell. But when cells reproduce, their DNA has to reproduce as well. The structure of DNA reveals how trillions of copies of the DNA in one of your cells can be made, and be almost exactly the sam ...
... Cells have to reproduce many times. In complex organisms, trillions of copies are made from one original cell. But when cells reproduce, their DNA has to reproduce as well. The structure of DNA reveals how trillions of copies of the DNA in one of your cells can be made, and be almost exactly the sam ...
“The function and synthesis of ribosomes.” Nature Reviews Mol Cell
... by the long extensions of four r-proteins, but these are too far away to participate directly in catalysis. From this, it was concluded that the peptidyl-transfer reaction is catalysed by RNA1,20. On the basis of the structure of the 50S subunit in complex with analogues that mimic the substrates fo ...
... by the long extensions of four r-proteins, but these are too far away to participate directly in catalysis. From this, it was concluded that the peptidyl-transfer reaction is catalysed by RNA1,20. On the basis of the structure of the 50S subunit in complex with analogues that mimic the substrates fo ...
How to design CRISPR crRNA for gene disruption
... than mismatches further away in the protospacer sequence. Therefore, off-target sites with mismatches near the PAM sequence are less likely to have an unwanted editing event than those with mismatches more distal from the PAM [4]. The output also displays information for genes that have been identif ...
... than mismatches further away in the protospacer sequence. Therefore, off-target sites with mismatches near the PAM sequence are less likely to have an unwanted editing event than those with mismatches more distal from the PAM [4]. The output also displays information for genes that have been identif ...
Genetic Profiling of Changes Underlying Different Sized Human
... massive RC tear groups suggested they are biologically distinct groups. We have identified a significant role for ECM related genes such as MMPs and ADAMs in RC tear pathogenesis. This suggests that upregulation of the reported ECM genes may play key roles in the development of tears, as they may re ...
... massive RC tear groups suggested they are biologically distinct groups. We have identified a significant role for ECM related genes such as MMPs and ADAMs in RC tear pathogenesis. This suggests that upregulation of the reported ECM genes may play key roles in the development of tears, as they may re ...
Strategies in the interfield discovery of the mechanism of protein
... focusing on chemical reactions and energy requirements for such strong covalent bonds to form. Biochemists often used in vitro experimental systems, such as Zamecnik’s cell-free rat liver preparation. As Zamecnik put it graphically: ‘The biochemist traditionally studies living cells by smashing them ...
... focusing on chemical reactions and energy requirements for such strong covalent bonds to form. Biochemists often used in vitro experimental systems, such as Zamecnik’s cell-free rat liver preparation. As Zamecnik put it graphically: ‘The biochemist traditionally studies living cells by smashing them ...
Core promoter
... when an Inr is inserted into a synthetic promoter downstream of six binding sites for transcription factor Sp1, the Inr supports high levels of transcription that initiate at a specific start site within the Inr. act synergistically when separated by 25–30 bp act independently when separated by more ...
... when an Inr is inserted into a synthetic promoter downstream of six binding sites for transcription factor Sp1, the Inr supports high levels of transcription that initiate at a specific start site within the Inr. act synergistically when separated by 25–30 bp act independently when separated by more ...
chapter 17 notes
... Evolution of the Genetic Code • The genetic code is nearly universal – Shared by organisms from the simplest bacteria to the most complex animals ...
... Evolution of the Genetic Code • The genetic code is nearly universal – Shared by organisms from the simplest bacteria to the most complex animals ...
lec39_2013 - Andrew.cmu.edu
... a) mRNA – messenger RNA is copy of the DNA that encodes a gene. mRNA specifies the order of amino acids to be used in making the protein. b) tRNA – transfer RNA is the dictionary the converts the codon to a specific amino acid. One part of the tRNA recognizes the codon, the other part contains the a ...
... a) mRNA – messenger RNA is copy of the DNA that encodes a gene. mRNA specifies the order of amino acids to be used in making the protein. b) tRNA – transfer RNA is the dictionary the converts the codon to a specific amino acid. One part of the tRNA recognizes the codon, the other part contains the a ...