Isr J Chem (2010) - Weizmann Institute of Science
... formation. We aim to define the minimal ribosomal component required for maintaining PTC structure and function, in order to shed light on the evolution of the ribosome. Since the discovery made in the 1960 s that the ribosome can catalyze peptide bond formation between minimal substrates, e. g. pur ...
... formation. We aim to define the minimal ribosomal component required for maintaining PTC structure and function, in order to shed light on the evolution of the ribosome. Since the discovery made in the 1960 s that the ribosome can catalyze peptide bond formation between minimal substrates, e. g. pur ...
The Concept of the Gene in Development and Evolution
... polypeptide clipped into four identical peptides. In contrast, an ascribed gene in silkworms produces five functionally distinct products (a diapause hormone, pheromone biosynthesis activating neuropeptide, and three other neuropeptides) cleaved from a 192 amino acid precursor (Xu et al. 1995), each ...
... polypeptide clipped into four identical peptides. In contrast, an ascribed gene in silkworms produces five functionally distinct products (a diapause hormone, pheromone biosynthesis activating neuropeptide, and three other neuropeptides) cleaved from a 192 amino acid precursor (Xu et al. 1995), each ...
S010
... microRNAs. Here, one transcript may be processed to produce multiple functional microRNA sequences. In addition, each microRNA precursor hairpin has the potential to produce two different mature microRNAs. We have investigated the evolutionary and functional relationships between the multiple produc ...
... microRNAs. Here, one transcript may be processed to produce multiple functional microRNA sequences. In addition, each microRNA precursor hairpin has the potential to produce two different mature microRNAs. We have investigated the evolutionary and functional relationships between the multiple produc ...
A Glossary of Molecular Biology Terms More can be found at http
... Cap: All eukaryotes have at the 5' end of their messages a structure called a "cap", consisting of a 7-methylguanosine in 5'-5' triphosphate linkage with the first nucleotide of the mRNA. It is added post-transcriptionally, and is not encoded in the DNA. Cap site: 1) In eukaryotes, the cap site is t ...
... Cap: All eukaryotes have at the 5' end of their messages a structure called a "cap", consisting of a 7-methylguanosine in 5'-5' triphosphate linkage with the first nucleotide of the mRNA. It is added post-transcriptionally, and is not encoded in the DNA. Cap site: 1) In eukaryotes, the cap site is t ...
Tobacco TTG2 regulates vegetative growth and seed production via
... serine-rich in the same region [27, 31]. These ARFs target auxin-responsive genes of the Small Auxin Up RNA (SAUR), Auxin/Indole-Acetic Acid inducible (AUX/IAA), and Gretchen Hagen 3 (GH3) gene families [31–33]. Different ARFs regulate the expression of target genes by binding the auxin response ele ...
... serine-rich in the same region [27, 31]. These ARFs target auxin-responsive genes of the Small Auxin Up RNA (SAUR), Auxin/Indole-Acetic Acid inducible (AUX/IAA), and Gretchen Hagen 3 (GH3) gene families [31–33]. Different ARFs regulate the expression of target genes by binding the auxin response ele ...
Jake Wang - Critical Review of the Rosetta Algorithm
... Proteins are linear chains of amino acids that evolved the property of folding into unique three-dimensional structures in order to perform complex biological functions. Determining their structures has far-reaching implications in science and medicine. For example, once the structure of a protein i ...
... Proteins are linear chains of amino acids that evolved the property of folding into unique three-dimensional structures in order to perform complex biological functions. Determining their structures has far-reaching implications in science and medicine. For example, once the structure of a protein i ...
Module 3 Regulation of Gene Expression in Prokaryotes
... Expression of many prokaryotic genes is regulated – either induced (eg: catabolic) or repressed (eg: anabolic) Operons are coordinately regulated units of gene expression. May be defined as a unit of expression including structural genes and elements that control their expression; expression of the ...
... Expression of many prokaryotic genes is regulated – either induced (eg: catabolic) or repressed (eg: anabolic) Operons are coordinately regulated units of gene expression. May be defined as a unit of expression including structural genes and elements that control their expression; expression of the ...
Probing Essential Nucleobase Functional Groups in Aptamers and
... DNA (dNAIM) that is based on solid-phase synthesis of nucleotide analogue libraries (Figure 1a). In contrast to the phosphorothioate tag in NAIM analysis, we use the 20 -OH group of ribonucleotides as a chemical tag to encode nucleotide analogues in combinatorial DNA libraries. This is achieved by s ...
... DNA (dNAIM) that is based on solid-phase synthesis of nucleotide analogue libraries (Figure 1a). In contrast to the phosphorothioate tag in NAIM analysis, we use the 20 -OH group of ribonucleotides as a chemical tag to encode nucleotide analogues in combinatorial DNA libraries. This is achieved by s ...
Our system for annotation of articles is named “Text
... possible symbol, taking into account factors such as surface clues (presence of capital letters, numbers, greek letters, etc.). In other words, each possible symbol has a different minimum score, so that “AD” is recognized as a unlikely gene name, while “ftsZ” is seen as a very likely gene name. Aft ...
... possible symbol, taking into account factors such as surface clues (presence of capital letters, numbers, greek letters, etc.). In other words, each possible symbol has a different minimum score, so that “AD” is recognized as a unlikely gene name, while “ftsZ” is seen as a very likely gene name. Aft ...
A Major Species of Mouse μ-opioid Receptor mRNA and Its
... important role in gene regulation. The average length of 3⬘-UTR has increased dramatically throughout the evolutionary process, from 200 nucleotides in plant and fungi to 800 and more in humans and other vertebrates. This increase suggests a potential role of longer 3⬘-UTR in the regulation of more ...
... important role in gene regulation. The average length of 3⬘-UTR has increased dramatically throughout the evolutionary process, from 200 nucleotides in plant and fungi to 800 and more in humans and other vertebrates. This increase suggests a potential role of longer 3⬘-UTR in the regulation of more ...
IV RNA Synthesis: Transcription
... PCR is also used routinely in comparative or phylogenetic studies to amplify genes from various sources. In these cases the primers are made for regions of the gene that are conserved in sequence across a wide variety of organisms. Because 16S rRNA, a molecule used for phylogenetic analyses, has bot ...
... PCR is also used routinely in comparative or phylogenetic studies to amplify genes from various sources. In these cases the primers are made for regions of the gene that are conserved in sequence across a wide variety of organisms. Because 16S rRNA, a molecule used for phylogenetic analyses, has bot ...
Combination of Reverse Transcription and Multienzyme Restriction
... limitations of the traditional methods such as their low sensitivity, accuracy, and effectiveness in identifying pathogens within complex target food matrices. These new methods must be validated and standardized to become reference methods [5]. Polymerase chain reaction (PCR) is a powerful nucleic ...
... limitations of the traditional methods such as their low sensitivity, accuracy, and effectiveness in identifying pathogens within complex target food matrices. These new methods must be validated and standardized to become reference methods [5]. Polymerase chain reaction (PCR) is a powerful nucleic ...
Nucleotide sequence of the genomic RNA of pepper mild mottle
... corresponding proteins of ToMV and TMV, respectively. The 126K and 183K proteins are thought to be involved in viral replication because they have been detected in partially purified preparations of the viral polymerase complex and because they contain several sequence motifs which are conserved in ...
... corresponding proteins of ToMV and TMV, respectively. The 126K and 183K proteins are thought to be involved in viral replication because they have been detected in partially purified preparations of the viral polymerase complex and because they contain several sequence motifs which are conserved in ...
Molecular Evolution of Functional Nucleic Acids
... enzyme, while the catalytic domain of the former was 12 bases, which is smaller than that of the latter. These results indicate that the zinc ion, with which imidazoyl group is coordinated, could effectively work as catalyst. Perrin et al. obtained a modified DNA enzyme from a library of doubly modi ...
... enzyme, while the catalytic domain of the former was 12 bases, which is smaller than that of the latter. These results indicate that the zinc ion, with which imidazoyl group is coordinated, could effectively work as catalyst. Perrin et al. obtained a modified DNA enzyme from a library of doubly modi ...
Studies on the structure and function of 16S ribosomal RNA using
... molecules, exploiting the differential chemical reactivity of bases resulting from higher order structure. Their method utilizes end-labelling of the RNA, and displays sites of modification on a sequencing-type gel, made possible by aniline-induced strand scission at these positions. In order to ext ...
... molecules, exploiting the differential chemical reactivity of bases resulting from higher order structure. Their method utilizes end-labelling of the RNA, and displays sites of modification on a sequencing-type gel, made possible by aniline-induced strand scission at these positions. In order to ext ...
ppt - Chair of Computational Biology
... that mRNA. mRNA has been observed in tRNA, rRNA, and mRNA molecules of eukaryotes but not prokaryotes. RNA editing mechanisms include nucleoside modifications such as C to U and A to I deaminations, as well as non-templated nucleotide additions and insertions. RNA editing alters the amino acid seque ...
... that mRNA. mRNA has been observed in tRNA, rRNA, and mRNA molecules of eukaryotes but not prokaryotes. RNA editing mechanisms include nucleoside modifications such as C to U and A to I deaminations, as well as non-templated nucleotide additions and insertions. RNA editing alters the amino acid seque ...
File
... b. enzymes are made of DNA, and affected individuals lack DNA polymerase. c. many metabolic enzymes use DNA as a cofactor, and affected individuals have mutations that prevent their enzymes from interacting efficiently with DNA. d. certain metabolic reactions are carried out by ribozymes, and affect ...
... b. enzymes are made of DNA, and affected individuals lack DNA polymerase. c. many metabolic enzymes use DNA as a cofactor, and affected individuals have mutations that prevent their enzymes from interacting efficiently with DNA. d. certain metabolic reactions are carried out by ribozymes, and affect ...
TNFα signals through specialized factories where responsive coding
... gene transcription- this particularly effects the measurements of distances between the two RNA FISH signals and the argument that this due to colocalization to tx factories. A third related question has to do with the actual number of these NF-KB "factories" and how this matches up with the very hi ...
... gene transcription- this particularly effects the measurements of distances between the two RNA FISH signals and the argument that this due to colocalization to tx factories. A third related question has to do with the actual number of these NF-KB "factories" and how this matches up with the very hi ...