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This examination paper consists of 4 pages
This examination paper consists of 4 pages

... Occur only in bacterial genomes Contain more than one gene Contain more than one promoter Were discovered in the 19th century Contain long intergenic sequences ...
Go to Classzone - Issaquah Connect
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Document

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Cancer epigenetics



Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer prevention, detection, and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications, and dysregulation of DNA binding proteins. Several medications which have epigenetic impact are now used in several of these diseases.
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