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DNA structure and replication Three key features needed for any
DNA structure and replication Three key features needed for any

... 1) Must allow for faithful replication - each strand of DNA serves as a template for replication 2) Must have information content - the sequence of bases predict the sequence of amino acids in proteins 3) Must be able to change in order to explain mutations changes in DNA sequences result in changes ...
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ANSWERS - midterm study guide

... 4. What is the genotype for a male? For a female? _________________________________________________________ 5. How many copes of each chromosome does a normal human have? ______________________________________ 6. Contrast dominant and recessive. ______________________________________________________ ...
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TECHNICAL NOTE 4.1

... the offspring that brings our total to 46 chromosomes. If a parent were able to pass on all of its genes, then the offspring would be a clone of the parent. Because some of a parent’s genetic make-up may be detrimental (e.g., one ...
Recombinant DNA Technology
Recombinant DNA Technology

... Basic ingredients needed for DNA Recombination: A. Know the gene of interest and the species carrying that gene B. Need a species that can rapidly replicate its DNA and divide C. Need a species containing many restriction sites on its DNA D. Need restriction enzymes—these enzymes are able to cut dou ...
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Answers11.february

... are characteristic for eukaryotic genomes contain more than one gene contain more than one promoter contain always similar genes contain almost no intergenic sequences Telomers are located ...
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Human Genetics and Genetic Technology Test Review Jeopardy

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Answer Key DNA Review - John Bowne High School

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Review Sheet—Cell Division

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Methyl methanesulphonate (MMS, Fig

... and hydroxyl radical. These rather short-lived agents result in base oxidation or DNA strand breaks, resembling thereby effects of ionizing radiation (e.g. anti-cancer drug bleomycin). DNA damage has two more-or-less separate adverse effects on the cell. First, it is cytotoxic either directly – by p ...
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Answered copy of exam 3

... 4. What is unusual about the RSV particles that cause sarcomas? They carry an onc gene incorporated from a host genome 5. How do we know that humans also have a SRC gene? DNA hybridization to the cloned chicken gene C) At least 3 DNA viruses are associated with increased risk of cancer in humans. Li ...
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... 2. Immunocytochemistry- observe phospho-H3 throughout chromosomes during cell division Thus, this must play a role is chromosome condensation during mitosis 3. Models1. Phosphorylation + acetylation allows activation of gene expression, depending on context 2. Phospho-H3 loosens chromatin, enhancin ...
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NOTES: 12.1 - History of DNA (powerpoint)

... ● Heat killed pathogenic bacteria had passed their disease-causing ability to the harmless strain ● Griffith called this TRANSFORMATION – One strain of bacteria (harmless) had changed into the other (harmful, or disease-causing) ● Some factor was transferred from the heat killed cells to the live ce ...
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Mutations & Recombinant DNA

... Errors in Replication  Rare source of mutation  DNA polymerase carries out replication - adds nucleotides and proof reads new strand again template strand.  Usually mismatched pairs are replaced with the correct nucleotides.  Typically there is one mistake for everyone nucleotide pair replicate ...
12.1 - DNA History / Discovery
12.1 - DNA History / Discovery

... ● Heat killed pathogenic bacteria had passed their disease-causing ability to the harmless strain ● Griffith called this TRANSFORMATION – One strain of bacteria (harmless) had changed into the other (harmful, or disease-causing) ● Some factor was transferred from the heat killed cells to the live ce ...
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DNA NOTES

... 19. In the cytoplasm, mRNA attaches to a ________________. The ________________, with its attached mRNA, is now ready to synthesize a __________________. 20. During Translation, a __________ molecule transfers an _____________________to the ribosome. Each new ______________________links with the pre ...
MS Word file
MS Word file

... Recombination takes place between introduced genes and the bacterial chromosome. Competent cells: cells that take up DNA Transformants: cells that receive genetic material Cotransformed: cells that are transformed by two or more genes Bacterial Genome Sequences: 1 ~ 4 million base pairs of DNA Horiz ...
Worksheet – DNA and Protein Synthesis Biology 11 Name: DNA
Worksheet – DNA and Protein Synthesis Biology 11 Name: DNA

... A. it stays in the nucleus and is copied by DNA B. it carries amino acids to the growing polypeptide chain C. it makes up the ribosomes and provides the site for protein synthesis D. it is transcribed from the DNA and carries the information to the ribosome 6. Read the following DNA sequence left to ...
Human Genomic DNA Quality Controls for aCGH and Microarray
Human Genomic DNA Quality Controls for aCGH and Microarray

... comparative genomic hybridization (aCGH) testing? Are you doing other microarraybased analysis of DNA? You need external controls as a hybridization standard and to ensure your assays are performing correctly. For external controls, you can rely on ParagonDx aCGH Human Genomic DNA Quality Controls. ...
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Cancer epigenetics



Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer prevention, detection, and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications, and dysregulation of DNA binding proteins. Several medications which have epigenetic impact are now used in several of these diseases.
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