Article On the Complexity of Chloroplast RNA
... Most of these genes are required specifically for splicing of only one of the two split introns. At least seven genes are essential for trans-splicing of the first intron, some of which are necessary for processing of tscA from a polycistronic precursor (Hahn et al. 1998; Rivier 2000; Balczun et al. ...
... Most of these genes are required specifically for splicing of only one of the two split introns. At least seven genes are essential for trans-splicing of the first intron, some of which are necessary for processing of tscA from a polycistronic precursor (Hahn et al. 1998; Rivier 2000; Balczun et al. ...
D. melanogaster - GEP Community Server
... alternate chromatin structure critical for regulation in this heterochromatic domain. PLoS Genet. 2012 Sep;8(9):e1002954. ...
... alternate chromatin structure critical for regulation in this heterochromatic domain. PLoS Genet. 2012 Sep;8(9):e1002954. ...
The biased nucleotide composition of the HIV genome: a constant
... percentage of adenine (A) nucleotides, while being extremely poor in cytosine (C). Such a deviant base composition has implications for the amino acids that are encoded by the open reading frames (ORFs), both in the requirement of specific tRNA species and in the preference for amino acids encoded b ...
... percentage of adenine (A) nucleotides, while being extremely poor in cytosine (C). Such a deviant base composition has implications for the amino acids that are encoded by the open reading frames (ORFs), both in the requirement of specific tRNA species and in the preference for amino acids encoded b ...
Alternative Splicing
... Half of the patients suffering from those diseases carry mutations that effect pre-mRNA splicing (18, 19). Another example for primary splicing disorders is found in fronto-temporal dementia patients. This syndrome is an autosomal dominant disorder linked to chromosome 17. Splicing defects result in ...
... Half of the patients suffering from those diseases carry mutations that effect pre-mRNA splicing (18, 19). Another example for primary splicing disorders is found in fronto-temporal dementia patients. This syndrome is an autosomal dominant disorder linked to chromosome 17. Splicing defects result in ...
Recurrent patterns of DNA copy number alterations in tumors reflect
... tumors to increase the expression level of 'amplicon target genes'. The authors invest a lot of effort to show in various ways that glycolysis-associated genes are often amplified (and hypotheses that these genes may be 'drivers') - but do they also represent the top-ranked enriched pathway when per ...
... tumors to increase the expression level of 'amplicon target genes'. The authors invest a lot of effort to show in various ways that glycolysis-associated genes are often amplified (and hypotheses that these genes may be 'drivers') - but do they also represent the top-ranked enriched pathway when per ...
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... Transcriptional repression is an essential mechanism in the control of differential gene expression [1]. Repressor proteins can affect transcription by multiple mechanisms. Repression may occur by directly targeting components of the RNA polymerase II (RNAPII) core transcription machinery to block t ...
... Transcriptional repression is an essential mechanism in the control of differential gene expression [1]. Repressor proteins can affect transcription by multiple mechanisms. Repression may occur by directly targeting components of the RNA polymerase II (RNAPII) core transcription machinery to block t ...
Bridging structural biology and genomics: assessing protein
... and genetic protein-interaction studies. The 3D structures of RNA polymerase II, the proteasome and the Arp2/3 complex, which have 10, 14 and 7 subunits, respectively, were examined to identify stable protein–protein interaction interfaces, defined as more than 800 Å2 of contacting surface area. Thi ...
... and genetic protein-interaction studies. The 3D structures of RNA polymerase II, the proteasome and the Arp2/3 complex, which have 10, 14 and 7 subunits, respectively, were examined to identify stable protein–protein interaction interfaces, defined as more than 800 Å2 of contacting surface area. Thi ...
Nonconventional Initiation Complex Assembly by STAT and NF
... Inducible nitric oxide synthase (iNOS), the enzyme encoded by the Nos2 gene ...
... Inducible nitric oxide synthase (iNOS), the enzyme encoded by the Nos2 gene ...
Origin and evolution of the slime molds (Mycetozoa)
... nucleotides of overlap, suggesting the presence of a single, active tef locus in this genome. The Physarum tef gene contains a single 142-nucleotide intron, which lies at a position identical to that of an intron found in both vertebrates and invertebrates (Fig. 1). Both Dictyostelium tef genes, for ...
... nucleotides of overlap, suggesting the presence of a single, active tef locus in this genome. The Physarum tef gene contains a single 142-nucleotide intron, which lies at a position identical to that of an intron found in both vertebrates and invertebrates (Fig. 1). Both Dictyostelium tef genes, for ...
The sequence of a gene encoding convicilin from pea
... pea seeds, in addition to legumin and vicilin [1]. It can be purified from both legumin and vicilin, and it consists solely of polypeptides of Mr approx. 71 000. It does not thus contain polypeptides found in either of the two major storage proteins [2]. On the other hand, convicilin is antigenicall ...
... pea seeds, in addition to legumin and vicilin [1]. It can be purified from both legumin and vicilin, and it consists solely of polypeptides of Mr approx. 71 000. It does not thus contain polypeptides found in either of the two major storage proteins [2]. On the other hand, convicilin is antigenicall ...
Alternative Splicing in Higher Plants
... structural diversity (genome wide) – RT-PCR/RACE of a particular locus and looking for alternate isoforms (locus specific) – Microarrays that cover the locus can be used to detect alternate isoforms (not common in plants) ...
... structural diversity (genome wide) – RT-PCR/RACE of a particular locus and looking for alternate isoforms (locus specific) – Microarrays that cover the locus can be used to detect alternate isoforms (not common in plants) ...
Jigsaw handout - the Biology Scholars Program Wiki
... Summary of background information given in a reading and reinforced in a short lecture: The lac operon contains genes required for the uptake and utilization of the sugar, lactose. When lactose is not present, the proteins encoded by the genes are not needed and the operon is not transcribed. When ...
... Summary of background information given in a reading and reinforced in a short lecture: The lac operon contains genes required for the uptake and utilization of the sugar, lactose. When lactose is not present, the proteins encoded by the genes are not needed and the operon is not transcribed. When ...
Supplemental Table 1 and Figure Legends
... Panel A. Pair plots showing correlations between selected samples: Gene expression intensities obtained from samples containing 100 ng of RNA extracted from MDA-MB-468 cells considered as benchmarks and correlated with intensities obtained in profiles using decreasing RNA inputs, respectively 10 ng, ...
... Panel A. Pair plots showing correlations between selected samples: Gene expression intensities obtained from samples containing 100 ng of RNA extracted from MDA-MB-468 cells considered as benchmarks and correlated with intensities obtained in profiles using decreasing RNA inputs, respectively 10 ng, ...
Genes: Structure, Replication, and Mutation
... the stage for the research that first showed that DNA was the genetic material. Griffith found that if he boiled virulent bacteria and injected them into mice, the mice were not affected and no pneumococci could be recovered from the animals. When he injected a combination of killed virulent bacteri ...
... the stage for the research that first showed that DNA was the genetic material. Griffith found that if he boiled virulent bacteria and injected them into mice, the mice were not affected and no pneumococci could be recovered from the animals. When he injected a combination of killed virulent bacteri ...
The Structures of DNA and RNA
... focused attention on its structure. It was hoped that knowledge of the structure would reveal how DNA carries the genetic messages that are replicated when chromosomes divide to produce two identical copies of themselves. During the late 1940s and early 1950s, several research groups in the United S ...
... focused attention on its structure. It was hoped that knowledge of the structure would reveal how DNA carries the genetic messages that are replicated when chromosomes divide to produce two identical copies of themselves. During the late 1940s and early 1950s, several research groups in the United S ...
computation for chIP-seq and rNA-seq studies
... novel tag patterns as background. Components of 12 published software packages are summarized in Classes of ChIP-seq signals. Consistent with previous ChIP-chip Table 1. The simplest approach for calling enriched regions in ChIP-seq results, ChIP-seq tag enrichments or ‘peaks’ generated by typical e ...
... novel tag patterns as background. Components of 12 published software packages are summarized in Classes of ChIP-seq signals. Consistent with previous ChIP-chip Table 1. The simplest approach for calling enriched regions in ChIP-seq results, ChIP-seq tag enrichments or ‘peaks’ generated by typical e ...
The role of Dby mRNA in early development of male mouse zygotes
... and shedding cytoplasm during the later stage of spermatogenesis. However, recent evidence suggests that a complex specific mRNA population is retained in freshly ejaculated spermatozoa of several species [1–4]. In addition, some spermatozoa mRNAs are transferred into the oocyte during fertilization ...
... and shedding cytoplasm during the later stage of spermatogenesis. However, recent evidence suggests that a complex specific mRNA population is retained in freshly ejaculated spermatozoa of several species [1–4]. In addition, some spermatozoa mRNAs are transferred into the oocyte during fertilization ...
Full-Text PDF
... (5-methoxycarbonylmethyl(2-thio)uridine) modifications at position 34 from the anticodon loop of some tRNAs (Figure 2; [13,39]). In S. cerevisiae, the formation of mcm5 (s2 )U involves at least 15 proteins. The first reaction, consisting of the addition of the carboxymethyl group at position 5 of th ...
... (5-methoxycarbonylmethyl(2-thio)uridine) modifications at position 34 from the anticodon loop of some tRNAs (Figure 2; [13,39]). In S. cerevisiae, the formation of mcm5 (s2 )U involves at least 15 proteins. The first reaction, consisting of the addition of the carboxymethyl group at position 5 of th ...
New Developments in the Embryology Laboratory
... nucleus (small nuclear RNAs)and in the nucleolus (small nucleolar RNAs) are important components of transcriptomics • Proportion of mRNAs in a transcriptome account for only 1-2% of total RNA content in somatic cells ...
... nucleus (small nuclear RNAs)and in the nucleolus (small nucleolar RNAs) are important components of transcriptomics • Proportion of mRNAs in a transcriptome account for only 1-2% of total RNA content in somatic cells ...
as a PDF
... in cellular genes, the biological importance of recoding in gene regulation, and ways to identify new recoded genes. Introduction Postgenomic studies constitute one of the current challenges in biology due to the burgeoning quantity of genome sequence available and the difficulties in utilizing the ...
... in cellular genes, the biological importance of recoding in gene regulation, and ways to identify new recoded genes. Introduction Postgenomic studies constitute one of the current challenges in biology due to the burgeoning quantity of genome sequence available and the difficulties in utilizing the ...
Module 7 – Microbial Molecular Biology and Genetics
... thymine in RNA and differs from thymine by lacking a methyl group on its ring. Uracil is not usually found in DNA, occurring only as a breakdown product of cytosine. In addition to RNA and DNA a large number of artificial nucleic acid analogues have also been created to study the proprieties of nucl ...
... thymine in RNA and differs from thymine by lacking a methyl group on its ring. Uracil is not usually found in DNA, occurring only as a breakdown product of cytosine. In addition to RNA and DNA a large number of artificial nucleic acid analogues have also been created to study the proprieties of nucl ...
Chapter 2. Structures of Nucleic Acids
... DNA and RNA are both nucleic acids, which are the polymeric acids isolated from the nucleus of cells. DNA and RNA can be represented as simple strings of letters, where each letter corresponds to a particular nucleotide, the monomeric component of the nucleic acid polymers. Although this conveys alm ...
... DNA and RNA are both nucleic acids, which are the polymeric acids isolated from the nucleus of cells. DNA and RNA can be represented as simple strings of letters, where each letter corresponds to a particular nucleotide, the monomeric component of the nucleic acid polymers. Although this conveys alm ...
Chpt2_Struc_Nucleic_Acids.doc
... DNA and RNA are both nucleic acids, which are the polymeric acids isolated from the nucleus of cells. DNA and RNA can be represented as simple strings of letters, where each letter corresponds to a particular nucleotide, the monomeric component of the nucleic acid polymers. Although this conveys alm ...
... DNA and RNA are both nucleic acids, which are the polymeric acids isolated from the nucleus of cells. DNA and RNA can be represented as simple strings of letters, where each letter corresponds to a particular nucleotide, the monomeric component of the nucleic acid polymers. Although this conveys alm ...
Snímek 1
... Mechanisms proposed to explain how reduced SMN levels cause SMA According to one hypothesis, reduced SMN levels result in reduced assembly of Sm proteins onto snRNA. This unevenly alters the levels of specific endogenous snRNPs, such as those used to splice minor introns (particularly U11) from pre ...
... Mechanisms proposed to explain how reduced SMN levels cause SMA According to one hypothesis, reduced SMN levels result in reduced assembly of Sm proteins onto snRNA. This unevenly alters the levels of specific endogenous snRNPs, such as those used to splice minor introns (particularly U11) from pre ...
RNA-based regulation of genes of tryptophan synthesis
... In many organisms tryptophan serves as the precursor of other biologically essential compounds, i.e., niacin in most eukaryotes, indoleacetic acid in most plants, and indole in many bacte- FIGURE 2. Organization of the trp operon of E. coli. The genes of E. coli required for ria. Thus the regulatory ...
... In many organisms tryptophan serves as the precursor of other biologically essential compounds, i.e., niacin in most eukaryotes, indoleacetic acid in most plants, and indole in many bacte- FIGURE 2. Organization of the trp operon of E. coli. The genes of E. coli required for ria. Thus the regulatory ...