Additional file - Supplementary material
... assumption that genes with the GO category of interest have the same probability of being chosen and this probability is different from the probability of choosing the other genes. In order to use the Wallenius distribution, the probabilities for the two groups needs to be calculated. The Wallenius ...
... assumption that genes with the GO category of interest have the same probability of being chosen and this probability is different from the probability of choosing the other genes. In order to use the Wallenius distribution, the probabilities for the two groups needs to be calculated. The Wallenius ...
17 Cell Differentiation and Gene Expression
... Gene expression is the process in which the information stored in DNA is used to produce a functional gene product. Gene products are either proteins or noncoding RNAs, such as tRNA and rRNA, which play essential roles in protein synthesis, but do not code for proteins. Gene expression is regulated ...
... Gene expression is the process in which the information stored in DNA is used to produce a functional gene product. Gene products are either proteins or noncoding RNAs, such as tRNA and rRNA, which play essential roles in protein synthesis, but do not code for proteins. Gene expression is regulated ...
"Mendel`s Mouse" article
... ordinary collection of rodents, but their DNA is quite special. The animals belong to 40 strains, each of which has been inbred for so long that its mice have identical genes. “The diversity across these 40 mouse strains is as great as or greater than that of the entire human population,” Jackson ge ...
... ordinary collection of rodents, but their DNA is quite special. The animals belong to 40 strains, each of which has been inbred for so long that its mice have identical genes. “The diversity across these 40 mouse strains is as great as or greater than that of the entire human population,” Jackson ge ...
pdf
... Silencers are cis-acting regulatory sequences that reduce the expression from a promoter in a manner independent of position or orientation - i.e. they have the opposite effect of an enhancer. Two examples are the silencers that prevent expression of the a or α genes at the silent loci of the mating ...
... Silencers are cis-acting regulatory sequences that reduce the expression from a promoter in a manner independent of position or orientation - i.e. they have the opposite effect of an enhancer. Two examples are the silencers that prevent expression of the a or α genes at the silent loci of the mating ...
Expression of the Floral B-function Gene SLM2 in Female Flowers of
... In higher plants, the floral primordia are arranged in four different whorls, containing sepals, petals, stamens and carpels. The regulation of floral organ identity has been explained by the ABC model (Coen and Meyerowitz 1991, Weigel and Meyerowitz 1994), in which the A-function gene specifies sep ...
... In higher plants, the floral primordia are arranged in four different whorls, containing sepals, petals, stamens and carpels. The regulation of floral organ identity has been explained by the ABC model (Coen and Meyerowitz 1991, Weigel and Meyerowitz 1994), in which the A-function gene specifies sep ...
Paper - Ran Blekhman
... Changes in gene expression have been suggested to play a major role in mammalian evolution. In eukaryotes, gene expression is primarily controlled by sites, such as transcription factor binding sites (TFBSs), located in the noncoding region of the genome. The majority of these TFBSs remain unannotat ...
... Changes in gene expression have been suggested to play a major role in mammalian evolution. In eukaryotes, gene expression is primarily controlled by sites, such as transcription factor binding sites (TFBSs), located in the noncoding region of the genome. The majority of these TFBSs remain unannotat ...
JointCluster
... interactions (protein-DNA) maintain and regulate the cell's processes. • Expression of molecules (proteins or transcripts of genes) provide a snapshot of the cell’s state. • Researchers have exploited the complementarity of both. ...
... interactions (protein-DNA) maintain and regulate the cell's processes. • Expression of molecules (proteins or transcripts of genes) provide a snapshot of the cell’s state. • Researchers have exploited the complementarity of both. ...
cis-Regulatory Elements and Chromatin State
... regulation. The MADS box factors FLOWERING LOCUS C (FLC) and SHORT VEGETATIVE PHASE (SVP) form a complex that associates with regions within the proximal FT promoter and the first intron that comprise CArG boxes, although the importance of these elements for FT regulation has not yet been demonstrat ...
... regulation. The MADS box factors FLOWERING LOCUS C (FLC) and SHORT VEGETATIVE PHASE (SVP) form a complex that associates with regions within the proximal FT promoter and the first intron that comprise CArG boxes, although the importance of these elements for FT regulation has not yet been demonstrat ...
Sequences 5` to Translation Start Regulate
... tissue specificity of expression. The extra regions of nucleotide sequence conservation between SSU301 and SSU611 might contribute to the high expression levels of these two genes. Studies that define the c/s-acting elements in 5' promoter regions generally use deletion analysis of the pertinent seq ...
... tissue specificity of expression. The extra regions of nucleotide sequence conservation between SSU301 and SSU611 might contribute to the high expression levels of these two genes. Studies that define the c/s-acting elements in 5' promoter regions generally use deletion analysis of the pertinent seq ...
Genes and MS
... Research has already discovered several key things about genes and MS: - There are many genes involved in MS. Each only has a tiny part to play. - There may be a link between vitamin D levels and genes associated with someone developing MS (see below).4 - Certain genes might be similar to people wit ...
... Research has already discovered several key things about genes and MS: - There are many genes involved in MS. Each only has a tiny part to play. - There may be a link between vitamin D levels and genes associated with someone developing MS (see below).4 - Certain genes might be similar to people wit ...
Genome-wide expression analysis of cultured
... BACKGROUND: The pathologic features of Down syndrome are assumed to be the result of over-expression of genes located on chromosome 21 and/or a more global transcriptional misregulation that crosses chromosomal borders. METHODS: To address this issue, four RNA samples from trisomy 21 placentas and f ...
... BACKGROUND: The pathologic features of Down syndrome are assumed to be the result of over-expression of genes located on chromosome 21 and/or a more global transcriptional misregulation that crosses chromosomal borders. METHODS: To address this issue, four RNA samples from trisomy 21 placentas and f ...
Workshop_I
... important preprocessing steps for microarray data analysis. • Statistical methods are available for selecting significantly up- or down-regulated genes. • Clustering analysis is widely used to explore and visualize microarray data. • The resulting significant or co-expressed genes can be further inv ...
... important preprocessing steps for microarray data analysis. • Statistical methods are available for selecting significantly up- or down-regulated genes. • Clustering analysis is widely used to explore and visualize microarray data. • The resulting significant or co-expressed genes can be further inv ...
Gene Section FSTL3 (follistatin-like 3 (secreted glycoprotein)) Atlas of Genetics and Cytogenetics
... Similar to follistatin, secreted FSTL3 was shown to bind activin A and with lower affinity several other members of the TGF beta family including activin B, myostatin and BMP2, BMP6, and BMP7 (but excluding for instance TGF beta and BMP4) (Tsuchida et al., 2000; Tortoriello et al., 2001; Sidis et al ...
... Similar to follistatin, secreted FSTL3 was shown to bind activin A and with lower affinity several other members of the TGF beta family including activin B, myostatin and BMP2, BMP6, and BMP7 (but excluding for instance TGF beta and BMP4) (Tsuchida et al., 2000; Tortoriello et al., 2001; Sidis et al ...
Leukaemia Section t(3;9)(q26;p23) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... ZBTB16 PLZF, ZFPM2/FOG2, JNK and the PI3K/AKT pathway. Role in cell cycle progression, likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differentiation. ...
... ZBTB16 PLZF, ZFPM2/FOG2, JNK and the PI3K/AKT pathway. Role in cell cycle progression, likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differentiation. ...
Week 8
... – Otherwise, they loose out to the others who do manage to maximize their growth rates in the same conditions and thus come to dominate the populations ...
... – Otherwise, they loose out to the others who do manage to maximize their growth rates in the same conditions and thus come to dominate the populations ...
Expression analysis of a chicory fructan 1‐exohydrolase gene
... the HE-TAIL-PCR product, two gene-speci®c primers ±1149 HindIII-for (5¢-GTAAGCTTCGCAGACCTCTATCCATATATTAGTTC-3¢) and ATGKpnI-rev (5¢-AAAGGTACCTCTTCATGATGAGTGTGTGTGTTTGG-3¢) were synthesized to amplify a 1149 bp promoter fragment using a proofreading Pfu DNA polymerase (Promega, Madison, WI, USA) and ...
... the HE-TAIL-PCR product, two gene-speci®c primers ±1149 HindIII-for (5¢-GTAAGCTTCGCAGACCTCTATCCATATATTAGTTC-3¢) and ATGKpnI-rev (5¢-AAAGGTACCTCTTCATGATGAGTGTGTGTGTTTGG-3¢) were synthesized to amplify a 1149 bp promoter fragment using a proofreading Pfu DNA polymerase (Promega, Madison, WI, USA) and ...
The Drosophila Expression System.
... • Your choice of DES® vector for inducible (pMT/V5-His), inducible/secreted (pMT/BiP/V5-His), or constitutive expression (pAc5.1/V5-His) • A positive expression control • pCoBlast or pCoHygro for stable selection ...
... • Your choice of DES® vector for inducible (pMT/V5-His), inducible/secreted (pMT/BiP/V5-His), or constitutive expression (pAc5.1/V5-His) • A positive expression control • pCoBlast or pCoHygro for stable selection ...
A gene dosage map of Chromosome 18
... We have created a first draft of a gene dosage map of Chromosome 18. We started this process by reviewing the function of each known RefSeq gene on Chromosome 18 using OMIM and literature searches. More specifically, we determined whether there is any evidence of disease resulting from a hemizygous ...
... We have created a first draft of a gene dosage map of Chromosome 18. We started this process by reviewing the function of each known RefSeq gene on Chromosome 18 using OMIM and literature searches. More specifically, we determined whether there is any evidence of disease resulting from a hemizygous ...
The Chromosomal Basis of Inheritance
... along inside edge of nuclear envelope selection of which X will inactivate occurs randomly & independently in each embryonic cell …. females are a mosaic of the 2 X chromosomes ...
... along inside edge of nuclear envelope selection of which X will inactivate occurs randomly & independently in each embryonic cell …. females are a mosaic of the 2 X chromosomes ...
1754-6834-4-30-S5
... constructed in this study are summarised in Tables 1, 2, and 3. The nucleotide sequences of the cbh genes expressed in this study were codonoptimized for expression in S. cerevisiae using the Codon Adaptation Index (CAI) calculator for expression in S. cerevisiae [2] or by proprietary gene design so ...
... constructed in this study are summarised in Tables 1, 2, and 3. The nucleotide sequences of the cbh genes expressed in this study were codonoptimized for expression in S. cerevisiae using the Codon Adaptation Index (CAI) calculator for expression in S. cerevisiae [2] or by proprietary gene design so ...
BIOLOGY
... processes in which DNA produces RNA and proteins. It can also include other factors, such as the rate at which RNA is degraded before it can be translated. Differential gene expression will result in varying concentrations and kinds of proteins in cells, causing them to look and function differently ...
... processes in which DNA produces RNA and proteins. It can also include other factors, such as the rate at which RNA is degraded before it can be translated. Differential gene expression will result in varying concentrations and kinds of proteins in cells, causing them to look and function differently ...