Julio`s MCB - Digital Access to Scholarship at Harvard
... precise balance between the transcriptional factors GATA-1 and GATA-2 is part of the erythroid cell fate decision (9). The “GATA switch,” where an increase in the GATA-1 level, facilitated by FOG-1, displaces GATA-2 from its binding site, provides an important mechanism of GATA-1 chromatin occupancy ...
... precise balance between the transcriptional factors GATA-1 and GATA-2 is part of the erythroid cell fate decision (9). The “GATA switch,” where an increase in the GATA-1 level, facilitated by FOG-1, displaces GATA-2 from its binding site, provides an important mechanism of GATA-1 chromatin occupancy ...
Rotaphor System 6.0
... In contrast to conventional PFGE instruments with fixed electrodes the patented Rotaphor® system features free rotating electrodes. Thus any angle can be set for the electric field. Changing field angles over the time are achieved by the precise movement of the rotor. This feature is of special impo ...
... In contrast to conventional PFGE instruments with fixed electrodes the patented Rotaphor® system features free rotating electrodes. Thus any angle can be set for the electric field. Changing field angles over the time are achieved by the precise movement of the rotor. This feature is of special impo ...
T-box-mediated control of the anabolic proline biosynthetic genes of
... (Holtmann & Bremer, 2004). Cells were grown in SMM under the indicated conditions and samples were harvested either in midexponential phase (OD578 0.5–0.8) or at specified points during the growth cycle. RNA was routinely isolated from 20 ml cultures. The total amount of RNA isolated was determined ...
... (Holtmann & Bremer, 2004). Cells were grown in SMM under the indicated conditions and samples were harvested either in midexponential phase (OD578 0.5–0.8) or at specified points during the growth cycle. RNA was routinely isolated from 20 ml cultures. The total amount of RNA isolated was determined ...
NIH Public Access
... condensation but appears to involve chromatin modifications controlled directly or indirectly by AURKB mediated phosphorylation. AURKB, which is highly over-expressed in many cancers, is known for its role at the mitotic spindle and centromeres, but Hall et al. (2009) surprisingly identified AURKB a ...
... condensation but appears to involve chromatin modifications controlled directly or indirectly by AURKB mediated phosphorylation. AURKB, which is highly over-expressed in many cancers, is known for its role at the mitotic spindle and centromeres, but Hall et al. (2009) surprisingly identified AURKB a ...
rec-mediated recombinational hot spot activity in bacteriophage
... In order to survey the distribution along the bacteriophage X chromosome of Rec-mediated recombination events, crosses are performed using conditions which block essentially all DNA synthesis. One parent is density-labeled and carries a genetic marker in the left terminal X gene ( A ) ,while the oth ...
... In order to survey the distribution along the bacteriophage X chromosome of Rec-mediated recombination events, crosses are performed using conditions which block essentially all DNA synthesis. One parent is density-labeled and carries a genetic marker in the left terminal X gene ( A ) ,while the oth ...
as a PDF - CiteSeerX
... Replication, DNA organization, and mismatch repair (MMR) can influence recombination. We examined the effects of altered replication due to a mutation in the polymerase d gene, long inverted repeats (LIRs) in motifs similar to those in higher eukaryotes, and MMR on intrachromosomal recombination bet ...
... Replication, DNA organization, and mismatch repair (MMR) can influence recombination. We examined the effects of altered replication due to a mutation in the polymerase d gene, long inverted repeats (LIRs) in motifs similar to those in higher eukaryotes, and MMR on intrachromosomal recombination bet ...
Chromosomes Carrying Meiotic Avoidance Loci
... Physical mapping and plant phenotyping were used to establish the genomic region critical for LOA function, which lies between two new genomic markers in H. praealtum. The chromosomal location of the LOA locus was determined by fluorescent in situ hybridization (FISH). LOA is located on a single chr ...
... Physical mapping and plant phenotyping were used to establish the genomic region critical for LOA function, which lies between two new genomic markers in H. praealtum. The chromosomal location of the LOA locus was determined by fluorescent in situ hybridization (FISH). LOA is located on a single chr ...
Molecular mechanics of the interactions of spermine with DNA: DNA
... the three central torsion angles are 180°, which forces the central diaminobutane moiety into a fully extended conformation and produces a single distance (approximately 6.3 A) between the secondary amino groups (data not shown). The aminopropyl groups attached to the secondary amino groups assume a ...
... the three central torsion angles are 180°, which forces the central diaminobutane moiety into a fully extended conformation and produces a single distance (approximately 6.3 A) between the secondary amino groups (data not shown). The aminopropyl groups attached to the secondary amino groups assume a ...
Trichothiodystrophy: Update on the sulfur
... of the XPD gene. Rarely, mutated XPB gene or an unidentified TTD-A gene may result in TTD. In UVsensitive TTD, the TFIIH transcription factor containing XPB and XPD helicase activities necessary for both transcription initiation and DNA repair is damaged. Beyond deficiency in the NER pathway, it is ...
... of the XPD gene. Rarely, mutated XPB gene or an unidentified TTD-A gene may result in TTD. In UVsensitive TTD, the TFIIH transcription factor containing XPB and XPD helicase activities necessary for both transcription initiation and DNA repair is damaged. Beyond deficiency in the NER pathway, it is ...
A Physical Gene Map of the Bacteriophage P22 Late
... 1974). The fragment present in low molar yield in the EcoRI digest has been shown to arise from a chromosome end at pat and EcoRI cleavage at the first site counterclockwise from pat (Jackson et CL, 1978a). The smaller Sal1 fragment (Sal1 B) (see Fig. 1) is derived in an analogous fashion from a mol ...
... 1974). The fragment present in low molar yield in the EcoRI digest has been shown to arise from a chromosome end at pat and EcoRI cleavage at the first site counterclockwise from pat (Jackson et CL, 1978a). The smaller Sal1 fragment (Sal1 B) (see Fig. 1) is derived in an analogous fashion from a mol ...
WOTD - Brookwood High School
... V:multiple alleles refer to a trait (one gene) which is coded for by more than two alleles. ...
... V:multiple alleles refer to a trait (one gene) which is coded for by more than two alleles. ...
Questions & Answer keys Test 2 Genetic engg.
... a. RNA is more stickier than DNA with nitrocellulose filter b. Once attached, RNA cannot be separated out from nitrocellulose filter c. RNA forms in bulk and sticks on nitrocellulose filter d. RNA bands do not binds with nitrocellulose filter ...
... a. RNA is more stickier than DNA with nitrocellulose filter b. Once attached, RNA cannot be separated out from nitrocellulose filter c. RNA forms in bulk and sticks on nitrocellulose filter d. RNA bands do not binds with nitrocellulose filter ...
Molecular Biology of Transcription and RNA Processing
... Three additional types of functional RNA perform specialized functions in eukaryotic cells only. Small nuclear RNA (snRNA) of various types is found in the nucleus of eukaryotic cells, where it participates in mRNA processing. Certain snRNAs unite with nuclear proteins to form ribonucleoprotein com ...
... Three additional types of functional RNA perform specialized functions in eukaryotic cells only. Small nuclear RNA (snRNA) of various types is found in the nucleus of eukaryotic cells, where it participates in mRNA processing. Certain snRNAs unite with nuclear proteins to form ribonucleoprotein com ...
Selection for TnlO Tet Repressor Binding to tet Operator
... We have constructed a genetic assay which selects positively for a functional interaction between Tet repressor and its cognate operator in Escherichia coli. In this strain Tet repressor blocks expression of lacl and lacZ. This leads to derepression of a lacPO controlled galK gene. The strain can be ...
... We have constructed a genetic assay which selects positively for a functional interaction between Tet repressor and its cognate operator in Escherichia coli. In this strain Tet repressor blocks expression of lacl and lacZ. This leads to derepression of a lacPO controlled galK gene. The strain can be ...
DNA
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
Primer on Molecular Biology
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
UCSD_PevznerMolecula.. - Purdue University :: Computer Science
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
Primer on Molecular Biology
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
... • basic physical and functional units of heredity. • specific sequences of DNA bases that encode instructions on how to make proteins. • Proteins ...
Slides: background and project plan
... • Each cell contains an identical copy of the whole genome - but utilizes only a subset of the genes to perform diverse, unique tasks • Most genes are highly regulated – their expression is limited to specific tissues, developmental stages, physiological condition • Main regulatory mechanism – trans ...
... • Each cell contains an identical copy of the whole genome - but utilizes only a subset of the genes to perform diverse, unique tasks • Most genes are highly regulated – their expression is limited to specific tissues, developmental stages, physiological condition • Main regulatory mechanism – trans ...
Polygenes and Modifier Genes for Tetracycline and
... that another locus, labelled pem, was involved in Pen resistance. From standard transformation experiments using PM50 DNA, only two phenotypic classes of Pen-resistant transformants were isolated. Type A was resistant to 0.05 pg ml-l and presumed to contain pen, and type B was resistant to 0.1 pg ml ...
... that another locus, labelled pem, was involved in Pen resistance. From standard transformation experiments using PM50 DNA, only two phenotypic classes of Pen-resistant transformants were isolated. Type A was resistant to 0.05 pg ml-l and presumed to contain pen, and type B was resistant to 0.1 pg ml ...
No Slide Title
... Quick Time™a nd a TIFF ( Uncomp res sed) deco mpr esso r ar e need ed to see this pictur e. Quick Time™a nd a TIFF ( Uncomp res sed) deco mpr esso r ar e need ed to see this pictur e. ...
... Quick Time™a nd a TIFF ( Uncomp res sed) deco mpr esso r ar e need ed to see this pictur e. Quick Time™a nd a TIFF ( Uncomp res sed) deco mpr esso r ar e need ed to see this pictur e. ...
Resolving Individuals Contributing Trace Amounts of DNA to Highly
... components of the mixture [8]. Nevertheless, these methods based on STRs expectedly suffer from limited power when using severely degraded DNA [8,9]. Mitochondrial DNA (mtDNA) based on hypervariable region sequencing is useful when analyzing degraded DNA due to its high copy number and improved stab ...
... components of the mixture [8]. Nevertheless, these methods based on STRs expectedly suffer from limited power when using severely degraded DNA [8,9]. Mitochondrial DNA (mtDNA) based on hypervariable region sequencing is useful when analyzing degraded DNA due to its high copy number and improved stab ...
MIDWESTERN ASSOCIATION OF FORENSIC SCIENTISTS, INC
... explained through the microscope by projection. Particles that require specialized analytical instrumentation for certain identification will be pointed out when encountered and the techniques of dealing with them will be described, specifically with respect to types of information that may be obtai ...
... explained through the microscope by projection. Particles that require specialized analytical instrumentation for certain identification will be pointed out when encountered and the techniques of dealing with them will be described, specifically with respect to types of information that may be obtai ...
Application Note: Targeted sequencing and chromosomal haplotype
... using just one primer pair complementary to a short locusspecific sequence. TLA is a strategy to selectively amplify complete loci on the basis of crosslinking physically proximal sequences. Unlike other targeted sequencing methods, TLA works without prior detailed locus information, as one primer p ...
... using just one primer pair complementary to a short locusspecific sequence. TLA is a strategy to selectively amplify complete loci on the basis of crosslinking physically proximal sequences. Unlike other targeted sequencing methods, TLA works without prior detailed locus information, as one primer p ...