Adaptive value of sex in microbial pathogens
... genetic errors but they differ in fundamental ways. Damages are physical irregularities in the genetic material, usually DNA, and may be recognizable at the structural level. Because they can be recognized directly in the DNA they may be correctly repaired if there is redundant information available ...
... genetic errors but they differ in fundamental ways. Damages are physical irregularities in the genetic material, usually DNA, and may be recognizable at the structural level. Because they can be recognized directly in the DNA they may be correctly repaired if there is redundant information available ...
Exercise II - GEP Community Server
... 8. Compare the gene model with the various biological evidence items. You will find that some BLASTN evidence shows Exon #4 to be about 110 nt long as opposed to 58 nt in the first model. 9. To build an alternative transcript for this gene: i. double-click the first model; ii. right-click (command- ...
... 8. Compare the gene model with the various biological evidence items. You will find that some BLASTN evidence shows Exon #4 to be about 110 nt long as opposed to 58 nt in the first model. 9. To build an alternative transcript for this gene: i. double-click the first model; ii. right-click (command- ...
Nucleotide Polymorphisms in the 2 Gene Define
... Additional nucleotide polymorphisms linked to expression levels of a2b1 define three alleles of the a2 gene. We have previously described the variation in a2b1 levels that exists among individuals. In studying this variability in expression levels, our analysis of mRNA from six individuals expressin ...
... Additional nucleotide polymorphisms linked to expression levels of a2b1 define three alleles of the a2 gene. We have previously described the variation in a2b1 levels that exists among individuals. In studying this variability in expression levels, our analysis of mRNA from six individuals expressin ...
Structural variations in the human genome
... With every single discovery that has been made, it seems as though ten new questions arise; the most important questions without exception being ‘what can we do with this new information’ and ‘what are the clinical implications of this knowledge’. Answering these (and other) questions is not always ...
... With every single discovery that has been made, it seems as though ten new questions arise; the most important questions without exception being ‘what can we do with this new information’ and ‘what are the clinical implications of this knowledge’. Answering these (and other) questions is not always ...
The Two Faces of Higher Eukaryotic DNA Replication Origins
... probably mechanism of initiation) to the classical E. coli, yeast, and SV40 origins. However, using the same twodimensional (2D) gel electrophoresis methods that had been employed to map yeast replication origins, Vaughn et al. (1990) obtained results very different from those obtained with yeast. T ...
... probably mechanism of initiation) to the classical E. coli, yeast, and SV40 origins. However, using the same twodimensional (2D) gel electrophoresis methods that had been employed to map yeast replication origins, Vaughn et al. (1990) obtained results very different from those obtained with yeast. T ...
rational selection of pcr-based platforms for pharmacogenomic testing
... usually amenable to automation and high-throughput processing with 96-well plates, the current industry standard, but can be further implemented by 384-well plate capabilities. Maximum automation can be achieved by fully integrated systems with robotic processing of 96- or 384-well plates throughout ...
... usually amenable to automation and high-throughput processing with 96-well plates, the current industry standard, but can be further implemented by 384-well plate capabilities. Maximum automation can be achieved by fully integrated systems with robotic processing of 96- or 384-well plates throughout ...
Cutting Edge: DNA Polymerases and Are Dispensable for Ig Gene
... whose contribution is crucial to diversify the third complementarity-determining region of Ig and TCR genes during V(D)J rearrangement; 2) despite a ubiquitous expression, a higher level of transcription in lymphoid tissues, in particular B cells from tonsils, but also, and obviously not in favor of ...
... whose contribution is crucial to diversify the third complementarity-determining region of Ig and TCR genes during V(D)J rearrangement; 2) despite a ubiquitous expression, a higher level of transcription in lymphoid tissues, in particular B cells from tonsils, but also, and obviously not in favor of ...
CHAPTER ONE INTRODUCTION 1
... phenotypes are summarized in Table 1.1. Over-expression of CyclinB1;1 and B1;2 enhanced cell proliferation that resulted into faster root growth in Brassica (Doerner et al., 1996) and in rice (Lee et al., 2003). In Arabidopsis, over-expression of Arath;CyclinB1;2 induced cell division with a reducti ...
... phenotypes are summarized in Table 1.1. Over-expression of CyclinB1;1 and B1;2 enhanced cell proliferation that resulted into faster root growth in Brassica (Doerner et al., 1996) and in rice (Lee et al., 2003). In Arabidopsis, over-expression of Arath;CyclinB1;2 induced cell division with a reducti ...
Virulence gene regulation in Salmonella enterica
... gastroenteritis is much higher (2). Salmonella infection follows ingestion of contaminated food, water or beverages and requires survival in the stomach and colonization of the small intestine. At this stage, the bacteria are seen to start multiplying and adhering to the intestinal mucosa. In the mo ...
... gastroenteritis is much higher (2). Salmonella infection follows ingestion of contaminated food, water or beverages and requires survival in the stomach and colonization of the small intestine. At this stage, the bacteria are seen to start multiplying and adhering to the intestinal mucosa. In the mo ...
How Does DNA Determine the Traits of an Organism
... How Does DNA Determine the Traits of an Organism? Introduction: In this simulation, you will examine the DNA sequence of a fictitious organism the Snork. Snorks were discovered on the planet Dee Enae in a distant solar system. Snorks only have one chromosome with eight genes on it. Your job is to an ...
... How Does DNA Determine the Traits of an Organism? Introduction: In this simulation, you will examine the DNA sequence of a fictitious organism the Snork. Snorks were discovered on the planet Dee Enae in a distant solar system. Snorks only have one chromosome with eight genes on it. Your job is to an ...
Physiological and phylogenetic analysis of rhizobia isolated from
... isolate second showed intermediate with Rhizobium leguminosarum and Rhizobium hainanense. For the confirmation of nitrogen fixing ability of isolates, nifH gene was amplified. Application of effective rhizobia strains as biofertilizers to improve legume production is an important approach in sustain ...
... isolate second showed intermediate with Rhizobium leguminosarum and Rhizobium hainanense. For the confirmation of nitrogen fixing ability of isolates, nifH gene was amplified. Application of effective rhizobia strains as biofertilizers to improve legume production is an important approach in sustain ...
16S rRNA Sequence Analysis of Bacteria Present in Foaming Activated Sludge Introduction
... Clone 5 did not fall into any of the groups in the dendogram (Fig. 1). However, a nucleotide sequence of approximately 440 nucleotides showed 97% similarity to members of group 1 i.e. Dietzia, Rhodococcus and Nocardia spp. that form part of the filamentous bacteria associated with activated sludge f ...
... Clone 5 did not fall into any of the groups in the dendogram (Fig. 1). However, a nucleotide sequence of approximately 440 nucleotides showed 97% similarity to members of group 1 i.e. Dietzia, Rhodococcus and Nocardia spp. that form part of the filamentous bacteria associated with activated sludge f ...
Illustrating Python via Bioinformatics Examples
... The instructions to the computer how the analysis is going to be performed are specified using the Python1 programming language. The forthcoming examples are simple illustrations of the type of problem settings and corresponding Python implementations that are encountered in bioinformatics. However, ...
... The instructions to the computer how the analysis is going to be performed are specified using the Python1 programming language. The forthcoming examples are simple illustrations of the type of problem settings and corresponding Python implementations that are encountered in bioinformatics. However, ...
Using the Wolbachia Bacterial Symbiont to Teach Inquiry
... the students can expect a positive Wolbachia diagnosis in one out of five insects. Positive (Wolbachia-infected) and negative (Wolbachia-uninfected) insect controls, Wolbachia DNA, and primers for PCR amplification of insect and Wolbachia genes are provided at no charge. Registration to obtain prime ...
... the students can expect a positive Wolbachia diagnosis in one out of five insects. Positive (Wolbachia-infected) and negative (Wolbachia-uninfected) insect controls, Wolbachia DNA, and primers for PCR amplification of insect and Wolbachia genes are provided at no charge. Registration to obtain prime ...
Scoring Guidelines - Ohio Assessment Systems
... gene that produces the protein in the Na+-K+ pump.” The second point is not earned because the response fails to describe how protein synthesis is required to express the gene for the Na+-K+ pump: “Protein synthesis is required to express this protein in the pump… the protein could not express the g ...
... gene that produces the protein in the Na+-K+ pump.” The second point is not earned because the response fails to describe how protein synthesis is required to express the gene for the Na+-K+ pump: “Protein synthesis is required to express this protein in the pump… the protein could not express the g ...
MIT Department of Biology 7.28, Spring 2005
... Double-strand breaks can occur anywhere in the genome. (However, it is true that the Spo11 proteins that initiate double strand breaks during meiosis in eukaryotes do show some site specificity. This results in some hot and cold regions for homologous recombination. ) Property 2: The components that ...
... Double-strand breaks can occur anywhere in the genome. (However, it is true that the Spo11 proteins that initiate double strand breaks during meiosis in eukaryotes do show some site specificity. This results in some hot and cold regions for homologous recombination. ) Property 2: The components that ...
Virginia State Science Olympiad Regional Tournament
... a. Mitosis results in four haploid daughter cells, while meiosis results in two diploid daughter cells. b. DNA synthesis only occurs once before either mitosis or meiosis. c. During anaphase I, homologous pairs of chromatids are separated; during regular anaphase, homologous pairs of chromosomes are ...
... a. Mitosis results in four haploid daughter cells, while meiosis results in two diploid daughter cells. b. DNA synthesis only occurs once before either mitosis or meiosis. c. During anaphase I, homologous pairs of chromatids are separated; during regular anaphase, homologous pairs of chromosomes are ...
Detection of genetically modified cotton seeds using PCR
... analysis. The reactions were carried out at 95°C for 3 min, followed by 35 cycles of amplification: denaturing at 94°C for 40 sec, annealing at 54°C (P-35S and nptII) and 58oC (cry1Ac) for 30 sec and extension at 72°C for 40 sec. The reactions were further subjected to 91 cycles of 0.5°C increments ...
... analysis. The reactions were carried out at 95°C for 3 min, followed by 35 cycles of amplification: denaturing at 94°C for 40 sec, annealing at 54°C (P-35S and nptII) and 58oC (cry1Ac) for 30 sec and extension at 72°C for 40 sec. The reactions were further subjected to 91 cycles of 0.5°C increments ...
Bioinformatics - Sequences and Computers
... Learn how information-bearing sequences are different from random sequences and become familiar with bioinformatics tools for the analysis of sequences. Language and DNA use sequences to communicate information. The sequence elements in language are letters and punctuation, in DNA they are the nucle ...
... Learn how information-bearing sequences are different from random sequences and become familiar with bioinformatics tools for the analysis of sequences. Language and DNA use sequences to communicate information. The sequence elements in language are letters and punctuation, in DNA they are the nucle ...
DNA How the Molecule of Heredity Carries, Replicates, and
... •Much of DNA’s sequence-specific information is accessible only when the double helix is unwound. •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. •Human genome is believed to be 250 million nucleotide ...
... •Much of DNA’s sequence-specific information is accessible only when the double helix is unwound. •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. •Human genome is believed to be 250 million nucleotide ...
DNA phosphorothioation inStreptomyces lividans: mutational
... sylated [1-3]. Altered or unusual bases in DNA molecules often have significant physiological implications, such as DNA replication control, gene regulation, or protection of the respective organisms from invasion by foreign DNA [4]. Page 1 of 8 (page number not for citation purposes) ...
... sylated [1-3]. Altered or unusual bases in DNA molecules often have significant physiological implications, such as DNA replication control, gene regulation, or protection of the respective organisms from invasion by foreign DNA [4]. Page 1 of 8 (page number not for citation purposes) ...
CHAPTER 9
... information can be obtained from this type of study? Why is it necessary to interrupt mating? Answer: An interrupted mating experiment is a procedure in which two bacterial strains are allowed to mate, and then the mating is interrupted at various time points. The interruption occurs by agitation of ...
... information can be obtained from this type of study? Why is it necessary to interrupt mating? Answer: An interrupted mating experiment is a procedure in which two bacterial strains are allowed to mate, and then the mating is interrupted at various time points. The interruption occurs by agitation of ...
Methylation of the Factor IX Gene is the Main Source of Mutations
... A total of 750 mutations in the human coagulation factor IX gene in 806 patients with hemophilia В were analyzed. It was found that 40% of all point mutations occur in 11 "hot spots," which are CG methylation sites where *CG TG or *CG CA substitutions take place. A mechanism is proposed which expl ...
... A total of 750 mutations in the human coagulation factor IX gene in 806 patients with hemophilia В were analyzed. It was found that 40% of all point mutations occur in 11 "hot spots," which are CG methylation sites where *CG TG or *CG CA substitutions take place. A mechanism is proposed which expl ...
Nucleotide Sequence of the Osmoregulatory proU Operon of
... are marked; a kilobase scale is included. The insert includes 5 kb of DNA clockwise of the BgIII site from the E. coli proU iocus (thin line) and 1 kb of Mu c DNA (thick line); the BglII site was lost in the process of construction of pHYD58 and is therefore shown within parentheses. The sequence to ...
... are marked; a kilobase scale is included. The insert includes 5 kb of DNA clockwise of the BgIII site from the E. coli proU iocus (thin line) and 1 kb of Mu c DNA (thick line); the BglII site was lost in the process of construction of pHYD58 and is therefore shown within parentheses. The sequence to ...