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Cloning and characterization of a phosphopantetheinyl transferase
Cloning and characterization of a phosphopantetheinyl transferase

... and NRPS genes are already known, such as the mycobactin biosynthetic gene cluster from Mycobacterium tuberculosis, which lacks the corresponding PPTase gene [24]. In fact, PPTase genes have not been found to be clustered with PKS genes in most of the polyketide biosynthetic gene clusters known to d ...
Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine
Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine

... were reported to have a multitude of cellular effects in addition to inhibition of gene expression via riboswitch binding [16,17,18,19]. Pleiotropic effects were also observed for compounds targeting the guanine riboswitch and at least one analog was reported to be possibly incorporated in DNA durin ...
Drug-Resistant Variants of Escherichia coli Thymidylate Synthase
Drug-Resistant Variants of Escherichia coli Thymidylate Synthase

... Pro-254 specifically affect the initial binding interactions between enzyme and cofactor and also alter the ability of the mutant enzymes to undergo conformational changes that occur on ternary complex formation. The crystal structure of P254S was determined at 1.5 Å resolution and is the most preci ...
Gene interactions and stroke risk in children with
Gene interactions and stroke risk in children with

... interpretations on a standardized form. If the interpretations differed, consensus was reached in discussion with the third neuroradiologist. This study included results from all MRI scans performed on eligible patients. ...
A selfish origin for recombination
A selfish origin for recombination

... 3. Gene conversion and recombination Crossing over is due to many (at least 11) different genes (Paques and Haber, 1999), the products of which are necessary in the different steps of the process. These genes have also other functions, especially for DNA repair, indeed the molecular machinery is alm ...
Program and Abstracts of the Twenty-Fifth International Conference
Program and Abstracts of the Twenty-Fifth International Conference

... The International Society For Antiviral Research (ISAR)  The Society was organized in 1987 as a non‐profit scientific organization for the purpose of advancing and  disseminating knowledge in all areas of antiviral research. To achieve this objective, the Society organizes an  annual meeting. The So ...
Microbiology
Microbiology

... and GRH2-50 mutations, we determined the DNA sequence of the corresponding left Tn5-DNA junctions. The partial amino acid sequences deduced were compared with sequences in the Swissprot and PIR Data Banks. N o homologous sequences were found to the predicted product encoded by the mutant locus of GR ...
Surface polysaccharide mutants of Rhizobium sp. (Acacia) strain
Surface polysaccharide mutants of Rhizobium sp. (Acacia) strain

... and GRH2-50 mutations, we determined the DNA sequence of the corresponding left Tn5-DNA junctions. The partial amino acid sequences deduced were compared with sequences in the Swissprot and PIR Data Banks. N o homologous sequences were found to the predicted product encoded by the mutant locus of GR ...
here - Genomes Unzipped
here - Genomes Unzipped

... Li et al.[1] sequenced cDNA from lymphoblastoid cell lines derived from 27 individuals whose genomes have been sequenced at low coverage [2], and identified 10,210 sites of mismatches between an individual’s mRNA and DNA sequences (RDD sites, for RNA-DNA difference). RDD sites included all possible ...
RHD - Labex
RHD - Labex

...  Wiener and Landsteiner discovered the Rh factor in 1937/1940  The importance of the Rh factor was the better blood finger print for criminal matters  M, N, or P factors where known and Rh factor was just an additional one  Later it was recognized that the new Rh factor was associated with probl ...
Functional characterization of dosage‐dependent lethal mutation of
Functional characterization of dosage‐dependent lethal mutation of

... which lacks the UBI4 gene, grows normally in the absence of any kind of stress. Previous studies from our laboratory established that over-expression of UbEP42 in this strain caused cell lysis even under normal conditions. SUB62, being a wild-type strain for UBI4, by contrast remained unaffected by ...
Bacteroides macacae - International Journal of Systematic and
Bacteroides macacae - International Journal of Systematic and

... subcutaneous abscesses and pyothoraxes of cats. The B. salivosus strains exhibited little DNA-DNA hybridization with members of previously described pigmented asaccharolytic Bacteroides species. Also, original DNA-DNA hybridization experiments revealed that the levels of hybridization between feline ...
Origins of Life PDF
Origins of Life PDF

... that the RNA could serve as a catalyst for the formation of a bond between the amino acids. If one RNA’s sequence happened to favor the production of a protein that then either protected the RNA or helped it replicate, this RNA would be favored by natural selection and would prosper, leaving more de ...
The Coat of Many Colors
The Coat of Many Colors

... inserted into the merle gene contains a long string of “A’s” that “turn off” the SILV gene so that it cannot produce the SILV protein helping to form melanosomes. It turns out that mutations occur in this string of “A’s”quite often as cells divide, decreasing the string’s length. The result is that ...
Woolfe, 2005
Woolfe, 2005

... Modules of transcription factor binding sites? ...
XistAR write up
XistAR write up

... First, as you can see from the diagram depicting the X inactivation center(XIC), Tsix is a gene antisense of Xist, which have been shown from other literature and as discussed in class, is a gene transcribed only from the active X chromosome in either iXCI or random XCI. Since Tsix is also antisense ...
Antiretroviral Therapy for HIV Infection: When to Initiate - IAS-USA
Antiretroviral Therapy for HIV Infection: When to Initiate - IAS-USA

Biology
Biology

... herbivores, carnivores, or omnivores. Food chains might also include decomposers (organisms that get nutrients and energy by breaking down the remains of dead organisms or animal waste) such as bacteria and fungi. Through the process of decomposition, they recycle nutrients like carbon and nitrogen ...
Bacteriophage A cloning system for the construction of
Bacteriophage A cloning system for the construction of

... of genes isolated by cDNA cloning techniques. Since their introduction (1, 2) these techniques have been refined to allow for the isolation of eukaryotic genes expressed at low frequencies. Oligonucleotide probes or antibodies to eukaryotic gene products are widely used for screening bacterial libra ...
Comparison of good-and bad-quality cork: application of high
Comparison of good-and bad-quality cork: application of high

... more highly represented in BQC are involved in DNA synthesis, RNA processing, proteolysis, and transcription factors related to the abiotic stress response. Putative stomatal/lenticular-associated genes which may be responsible for the disadvantageous higher number of lenticular channels in BQC are ...
Acanthamoeba mitochondrial 16S rDNA sequences: inferred
Acanthamoeba mitochondrial 16S rDNA sequences: inferred

... observed elsewhere for nuclear Rns DNA [3]. The exceptions were several mT4 strains with identical mitochondrial 16S rDNA sequences, but different nuclear sequences. There were a total of seven rns sequences, each from 2-10 strains, in which all strains shared the same sequence. One was a set of thr ...
31 Shareable Fragile X Facts (National Fragile X Foundation)
31 Shareable Fragile X Facts (National Fragile X Foundation)

... fragile X syndrome (FXS), fragile X-associated tremor/ataxia syndrome (FXTAS), fragile Xassociated primary ovarian insufficiency (FXPOI), and other premutation carrier issues. 2. The gene responsible for Fragile X is called FMR1 and is found on the X chromosome. Everyone has the FMR1 gene on their X ...
Pacing Guide
Pacing Guide

...  Laboratory Activity Flower dissection, plant structural observations (microscopic slides of the leaf, root, and stem of monocots and dicots), and observing the opening and closing of the stomata by changing solutions  CASE STUDY: Corn Under Construction Students will read a case narrative about g ...
Neutralizing scFv Antibodies against Infectious Bursal Disease Virus
Neutralizing scFv Antibodies against Infectious Bursal Disease Virus

... Infectious bursal disease (IBD) considered as one of the major viral diseases threatening the poultry industry worldwide. The causative agent of the IBD is Infectious bursal disease virus (IBDV) which replicates in developing B lymphocytes in the bursa of Fabricius leading to its destruction and bur ...
The influence of genomic imprinting on brain
The influence of genomic imprinting on brain

... loci, important in tissue functioning but not resource acquisition, that would function to decrease the costs associated with the hypothesized paternally expressed alleles (Haig & Westoby, 1989). As an illustration, if the genes involved in suckling are paternally expressed and maternally silent, ge ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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