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WOX4 and WOX14 act downstream of the PXY
WOX4 and WOX14 act downstream of the PXY

... suggesting that it may be regulated by PXY signalling. WOX14 expression was compared with that of WOX4, a previously identified target of PXY signalling (Hirakawa et al., 2010) in 5-day-old wildtype seedlings subjected to a 1- or 16-hour exposure to exogenous application of TDIF, the peptide derived ...
Chapter 1 - Bioinformatics Research Center
Chapter 1 - Bioinformatics Research Center

... DNA features that are associated with genes, such as open reading frames (ORFs), transcription start and termination sites, and exon/intron boundaries. Once a gene has been identified, it must be annotated, which entails linking its sequence to genetic data about the function, expression, and mutant ...
Chromosomal rearrangements and protein globularity changes in
Chromosomal rearrangements and protein globularity changes in

... into the pulmonary alveoli, these bacilli are phagocytosed by alveolar macrophages in which they survive to either cause local lesions or be disseminated to extra-pulmonary sites (Smith, 2003). Tuberculous meningitis (TBM) is a severe form of extrapulmonary TB that is associated with high morbidity ...
Biological Molecules
Biological Molecules

... Meiosis is the type of cell division that occurs in reproductive tissues. During meiosis two cellular divisions occur. In the first division, homologous chromosomes with two sister chromatids are separated, reducing the number of chromosomes. In the second division, sister chromatids are separated, ...
Mendel`s Genes: Toward a Full Molecular Characterization
Mendel`s Genes: Toward a Full Molecular Characterization

... since there is no evidence that other dwarfing mutations were available at this time, even though dwarf plants had been used agriculturally since at least the 1500s (Blixt 1972). It was White (1917) who gave the dwarf trait the gene symbol le. Between the 1950s and 1980s there were various functions ...
Imprinting evolution and the price of silence
Imprinting evolution and the price of silence

... covalent attachment of a methyl group. Unlike cytosine, 5methylcytosine is highly susceptible to spontaneous deamination that results in the generation of a TpG dinucleotide. Consequently, the mammalian genome has become progressively depleted of CpG dinucleotides through the course of evolution. Ho ...
Protein Acetylation as an Integral Part of Metabolism in Cancer
Protein Acetylation as an Integral Part of Metabolism in Cancer

... Acetylation of lysine is one of the major post-translational modifications of histone and non-histone proteins of eukaryotic cells. Acetylation has been indicated as an avenue for cellular response to environmental, nutritional and behavioral factors. At the same time, aberrant protein acetylation h ...
Phylogenetic Relationships Among Ascomycetes: Evidence from an
Phylogenetic Relationships Among Ascomycetes: Evidence from an

... Euascomycetes. Members of the Saccharomycetales differ from Euascomycetes both by the presence of a yeast phase and by the absence of both ascogenous hyphae and fruiting body formation (Alexopoulos, Mims, and Blackwell 1996). Euascomycetes are both the most complex in morphology and the most diverse ...
Probing the Performance Limits of the Escherichia
Probing the Performance Limits of the Escherichia

... (Winter et al., 1989). It is the objective of this study to utilize FBA and mixed-integer programming tools to select the mathematically optimal genes for recombination into E. coli from a metabolic database encompassing many genes from multiple species. The resulting pathways need not lie directly ...
Leaf shape: genetic controls and environmental factors
Leaf shape: genetic controls and environmental factors

... of leaves are very important factors influencing the success of plants. To absorb sufficient light energy, leaves must be as wide as possible. At the same time, to facilitate gas exchange (CO2, O2 and H2O), leaves must be as flat and thin as possible. However, if leaves are too wide and too thin, th ...
Recurrence time statistics: Versatile tools for genomic DNA
Recurrence time statistics: Versatile tools for genomic DNA

... of repeat-related structures [2, 3], and periodicity and quasi-periodicity, such as period-3, which is considered to reflect codon usage [4], and period 10-11, which may be due to the alternation of hydrophobic and hydrophilic amino acids [5] and DNA bending [6]. Extracting and understanding these s ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Astanand Jugessur ,Fedik Rahimov , Jeffrey C.Murray Genetic variants in IRF6 and risk of facial clefts: single marker and haplotype-based analyses in a population-based case control study of facial clefts in Norway. 2008 DOI: 10.1002/gepi.20314 Alexandre R Viera , Joseph R Avila , Jill Harrington Me ...
genetics - Liceocopernico.it
genetics - Liceocopernico.it

... Example I.I. Healthy people have a gene that specifies the normal protein structure of the red blood cell pigment called hemoglobin. Some anemic individuals have an altered form of this gene, i.e., an allele, which makes a defective hemoglobin protein unable to carry the normal amount of oxygen to t ...
The physics behind the larger scale organization of DNA in eukaryotes
The physics behind the larger scale organization of DNA in eukaryotes

... In this paper, we discuss in detail the organization of chromatin during a cell cycle at several levels. We show that current experimental data on large-scale chromatin organization have not yet reached the level of precision to allow for detailed modeling. We speculate in some detail about the poss ...
Pineal gland metastasis of auricular squamous cell carcinoma: an
Pineal gland metastasis of auricular squamous cell carcinoma: an

... hearing loss and chewing problems was evaluated at the ear, nose, and throat outpatient clinic. The patient’s history included the diagnosis of squamous cell carcinoma of the right auricula 15 years ago; the lesion was excised several times but recurred. Metastases to the right submandibular gland a ...
Sno/Ski Proto-Oncogene Family - The Newfeld Lab
Sno/Ski Proto-Oncogene Family - The Newfeld Lab

... mouse developed spontaneous lymphomas, suggesting that Sno could function as a tumor suppressor gene. Two other Sno knockout mice, generated with a similar strategy, did not develop lymphoma but rather displayed developmental defects in T-cell proliferation. Studies utilizing small interfer­ ing RNA ...
It was a Great, Green Year: Identification of a
It was a Great, Green Year: Identification of a

... particularly in the active site region. In vitro assays showed that CLD1 can dephytylate chlorophyll a and b, and pheophytin a, and that the mutant protein had higher activity than wild-type CLD1. Excess CLD1 activity caused mutant plants to accumulate chlorophyllides after heat shock and suppressio ...
The codon adaptation index-a measure of directional synonymous
The codon adaptation index-a measure of directional synonymous

... to be the usual host of T7) suggests that T7 genes are not so well adapted as E.coli's own genes, although there is clearly some adaptation (19,20). This seems to be confirmed by contrasting the distribution of CAI values for T7 genes with those of E.coli (Figure 1). However, the difference seen in ...
PPTX - Bioinformatics.ca
PPTX - Bioinformatics.ca

Hailey Spelman - Determining Cellular Fate: Pre- and Postnatal Methylation Effects on Gene Expression
Hailey Spelman - Determining Cellular Fate: Pre- and Postnatal Methylation Effects on Gene Expression

... relative to the strength of the promoter— that occurs in these areas, the greater the chance that low or no transcription will occur (Phillips). This repression is greater if the promoter itself is methylated, but distantly methylated sequences can also contribute to repression —especially if the me ...
(Chapter 3):Reproduction and Chromosome Transmission
(Chapter 3):Reproduction and Chromosome Transmission

... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
DNA Base Sequence Homology in Rhizoctonia solani Kuihn: Inter
DNA Base Sequence Homology in Rhizoctonia solani Kuihn: Inter

... (6), indicating genetic homogeneity among isolates within these groups. Hybridization between isolates of different AG was 30% or less (6,15). Ranges of DNA hybridization values varied for different AG, and lower levels of hybridization have confirmed lack of homogeneity among isolates within AG-1, ...
Sexual Reproduction and Meiosis
Sexual Reproduction and Meiosis

... partner. • These are called homologous pairs • One of the chromosomes from a pair comes from mom, and one comes from dad. • They code for the same type of traits ...
Oral Cancer Genetics: From Diagnosis to Treatment Natalie Kaweckyj, LDARF, CDA, CDPMA,
Oral Cancer Genetics: From Diagnosis to Treatment Natalie Kaweckyj, LDARF, CDA, CDPMA,

... Oral cancer is more common than cancers of the brain, liver, bone, stomach, cervix and ovaries; it is even more common than leukemia. When oral cancer is detected early, the cure rate can be as high as 96% depending on the location of the cancer. Unfortunately, by the time a medical or dental diagno ...
Word file: Analysis of alternative splicing in Drosophila
Word file: Analysis of alternative splicing in Drosophila

... sample is then washed repeatedly in PBT. To block non-specific antibody binding the tissue is then placed in 500 µl PBT supplemented with 5% Normal Goat Serum (Sigma) at room temperature and incubated for 1hour. The tissue is then immersed in PBT + 5% NGS along with primary antibodies directed at bo ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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