DNA sequencing: graph theory
... matches and 1 or 2 mismatches • Array Size: Effect of low fidelity can be decreased with longer l-mers, but array size increases exponentially in l. Array size is limited with current technology. • Practicality: SBH is still impractical. As DNA microarray technology improves, SBH may become practica ...
... matches and 1 or 2 mismatches • Array Size: Effect of low fidelity can be decreased with longer l-mers, but array size increases exponentially in l. Array size is limited with current technology. • Practicality: SBH is still impractical. As DNA microarray technology improves, SBH may become practica ...
Nucleic acid vaccines against rickettsial diseases and methods of use
... of many different mammalian species, some of them causing ...
... of many different mammalian species, some of them causing ...
The deleterious effect of missense mutations on pre
... (b) affect an invariant splice junction consensus sequence, or (c) were previously reported as pathogenic in the literature based on supporting functional data (Cotton and Scriver 1999). These criteria are not fulfilled if a missense mutation is detected. It is possible that the predicted amino acid ...
... (b) affect an invariant splice junction consensus sequence, or (c) were previously reported as pathogenic in the literature based on supporting functional data (Cotton and Scriver 1999). These criteria are not fulfilled if a missense mutation is detected. It is possible that the predicted amino acid ...
`Candidatus Phytoplasma mali`, `Candidatus Phytoplasma pyri` and
... Apple proliferation (AP), pear decline (PD) and European stone fruit yellows (ESFY) are among the most economically important plant diseases that are caused by phytoplasmas. Phylogenetic analyses revealed that the 16S rDNA sequences of strains of each of these pathogens were identical or nearly iden ...
... Apple proliferation (AP), pear decline (PD) and European stone fruit yellows (ESFY) are among the most economically important plant diseases that are caused by phytoplasmas. Phylogenetic analyses revealed that the 16S rDNA sequences of strains of each of these pathogens were identical or nearly iden ...
Identity-by-descent filtering of exome sequence data for disease
... may differ from one another, each affected person inherits a maternal and a paternal haplotype that are IBD to the maternal and paternal haplotypes in other affected siblings. We will refer to the intersection between the maternal and paternal IBD haplotypes among all affected individuals in a famil ...
... may differ from one another, each affected person inherits a maternal and a paternal haplotype that are IBD to the maternal and paternal haplotypes in other affected siblings. We will refer to the intersection between the maternal and paternal IBD haplotypes among all affected individuals in a famil ...
CHAPTER e18 Mitochondrial DNA and Heritable Traits and Diseases
... As a result of its circular structure and extranuclear location, the replication and transcription mechanisms of mtDNA differ from the corresponding mechanisms in the nuclear genome, whose nucleosomal packaging and structure are more complex. Since each mitochondrion contains many copies of mtDNA an ...
... As a result of its circular structure and extranuclear location, the replication and transcription mechanisms of mtDNA differ from the corresponding mechanisms in the nuclear genome, whose nucleosomal packaging and structure are more complex. Since each mitochondrion contains many copies of mtDNA an ...
Chromosomal translocations deregulated BCL6
... 1995). Its features and pattern of expression suggest that BCL6 may function as a DNA-binding transcription factor involved in the control of B cell differentiation and lymphoid organ development. Chromosomal translocations affecting band 3q27 represent reciprocal recombinations between this genomic ...
... 1995). Its features and pattern of expression suggest that BCL6 may function as a DNA-binding transcription factor involved in the control of B cell differentiation and lymphoid organ development. Chromosomal translocations affecting band 3q27 represent reciprocal recombinations between this genomic ...
Standards and guidelines for the interpretation of sequence
... the version being used in their test methods. Tools are available to provide correct HGVS nomenclature for describing variants (https://mutalyzer.nl).8 Clinical reports should include sequence reference(s) to ensure unambiguous naming of the variant at the DNA level, as well as to provide coding and ...
... the version being used in their test methods. Tools are available to provide correct HGVS nomenclature for describing variants (https://mutalyzer.nl).8 Clinical reports should include sequence reference(s) to ensure unambiguous naming of the variant at the DNA level, as well as to provide coding and ...
COMPUTATIONAL MODELING OF CHARGE TRANSFER IN NUCLEOBASE-AROMATIC AMINO ACID COMPLEXES Cristina BUTCHOSA ROBLES
... DNA have been widely explored, not much is known about the charge transfer capabilities of DNA when it interacts with amino acids. The present thesis models nucleobase-amino acid charge transfer reactions, which can serve as base for future computational investigations of charge transfer processes i ...
... DNA have been widely explored, not much is known about the charge transfer capabilities of DNA when it interacts with amino acids. The present thesis models nucleobase-amino acid charge transfer reactions, which can serve as base for future computational investigations of charge transfer processes i ...
Genetic tools for manipulating Acinetobacter baumannii genome: an
... as a temperature-sensitive replicon. The vector must also carry a selectable marker, usually an antibiotic resistance gene. Sometimes integration vectors also contain oriT so that the construct can be transferred to other bacteria by conjugation. This is especially helpful when the other transfer me ...
... as a temperature-sensitive replicon. The vector must also carry a selectable marker, usually an antibiotic resistance gene. Sometimes integration vectors also contain oriT so that the construct can be transferred to other bacteria by conjugation. This is especially helpful when the other transfer me ...
Introduction to Genetics
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
BT314 Virology
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
Introduction to the BLAST Suite and BLASTN
... The DEFINITION field is usually a brief description of the sequence, its origin, and any additional information that may prove valuable to the reader. The definition line for this record is unusually long, clearly taken from the title of the patent: “A group of genes which is differentially expresse ...
... The DEFINITION field is usually a brief description of the sequence, its origin, and any additional information that may prove valuable to the reader. The definition line for this record is unusually long, clearly taken from the title of the patent: “A group of genes which is differentially expresse ...
... increased protein kinase activity compared to ABL: 3BP1 (binding protein) binds normal ABL on SH3 domain, which prevents SH1 activation; with BCR/ABL, the first (N-terminal) exon of BCR binds to SH2, hidding SH3 which, as a consequence, cannot be bound to 3BP1; thereof, SH1 is activated. Oncogenesis ...
Gene Therapy and Transgenic Animals
... Future of Antisense-Based Biotechnology – The clinical experience to date should be considered part of the beginning of the story of antisense treatment, with more clinical trials of new antisense drugs soon expected. The promise – Currently over of 30antisense-based pharmaceutical and biotechnolog ...
... Future of Antisense-Based Biotechnology – The clinical experience to date should be considered part of the beginning of the story of antisense treatment, with more clinical trials of new antisense drugs soon expected. The promise – Currently over of 30antisense-based pharmaceutical and biotechnolog ...
Horizontal gene transfer from flowering plants to Gnetum
... possible because they possess unique characteristics. The gymnosperm-type nad1 intron 2 in Gnetum is characterized by 37–80 base pairs inserted before the GTGCG motif that is typical of the start of group II introns (Tables 3 and 4 and Figs. 1 and 6). Angiosperm-type nad1 exons found in Gnetum share ...
... possible because they possess unique characteristics. The gymnosperm-type nad1 intron 2 in Gnetum is characterized by 37–80 base pairs inserted before the GTGCG motif that is typical of the start of group II introns (Tables 3 and 4 and Figs. 1 and 6). Angiosperm-type nad1 exons found in Gnetum share ...
Whose Genetic Information Is It Anyway?
... Brandeis were concerned about by the lack of legal remedies available to individual's whose privacy was invaded, specifically the individuals who had their privacy violated by the press. Id. at 709. Warren and Brandeis argued that the gossip columns and abusive press tactics, were the result of nine ...
... Brandeis were concerned about by the lack of legal remedies available to individual's whose privacy was invaded, specifically the individuals who had their privacy violated by the press. Id. at 709. Warren and Brandeis argued that the gossip columns and abusive press tactics, were the result of nine ...
Evolutionary dynamics of nematode operons
... inferred only when all of its constituent genes were still present in the genome, because we are interested in the separation of constituent genes of an operon, rather than gene loss. However, there is a small probability that although all of the constituent genes are present, some of them have beco ...
... inferred only when all of its constituent genes were still present in the genome, because we are interested in the separation of constituent genes of an operon, rather than gene loss. However, there is a small probability that although all of the constituent genes are present, some of them have beco ...
The effecT of chlorinaTion of nucleoTide bases on The
... the second group), in which neither the twist of phosphate group, nor the turn of nucleotide bases around the C1′ – N1 glycoside bond or change of the sugar conformation were not the cause which significantly influenced the change of the conformational parame ters of the molecule. The example of th ...
... the second group), in which neither the twist of phosphate group, nor the turn of nucleotide bases around the C1′ – N1 glycoside bond or change of the sugar conformation were not the cause which significantly influenced the change of the conformational parame ters of the molecule. The example of th ...
abnormalities of chromosome structure
... The primary constituent of the chromatin is DEOXYRIBONUCLEIC ACID (DNA). Genes are composed of sequences of DNA. By serving as the blueprints of proteins in the body, genes influence all aspects of body structure and function. An error in one of these genes can lead to a recognizable genetic dis ...
... The primary constituent of the chromatin is DEOXYRIBONUCLEIC ACID (DNA). Genes are composed of sequences of DNA. By serving as the blueprints of proteins in the body, genes influence all aspects of body structure and function. An error in one of these genes can lead to a recognizable genetic dis ...