REDESIGN OF CARNITINE ACETYLTRANSFERASE SPECIFICITY BY PROTEIN ENGINEERING UNIVERSIDAD DE BARCELONA
... Choline acetyltransferase (ChAT) catalyzes a similar reaction to CrAT, with the difference that in ChAT the acetyl group from acetyl-CoA is transferred to choline instead of carnitine. Cronin (1998) successfully redesigned ChAT to use carnitine instead of its natural substrate choline. In the presen ...
... Choline acetyltransferase (ChAT) catalyzes a similar reaction to CrAT, with the difference that in ChAT the acetyl group from acetyl-CoA is transferred to choline instead of carnitine. Cronin (1998) successfully redesigned ChAT to use carnitine instead of its natural substrate choline. In the presen ...
Updated slides on graph algorithms for DNA sequencing
... Benzer’s Experiment • Idea: infect bacteria with pairs of mutant T4 bacteriophage (virus) • Each T4 mutant has an unknown interval deleted from its genome • If the two intervals overlap: T4 pair is missing part of its genome and is disabled – bacteria survive • If the two intervals do not overlap: T ...
... Benzer’s Experiment • Idea: infect bacteria with pairs of mutant T4 bacteriophage (virus) • Each T4 mutant has an unknown interval deleted from its genome • If the two intervals overlap: T4 pair is missing part of its genome and is disabled – bacteria survive • If the two intervals do not overlap: T ...
1 - Test Bank Corp
... The proposition that heritable characteristics that provide a survival or reproductive advantage are more likely to be passed on to subsequent generations is known as: A) Natural selection B) Genetic advantage C) Genetic cost D) Selective advantage Ans: a ...
... The proposition that heritable characteristics that provide a survival or reproductive advantage are more likely to be passed on to subsequent generations is known as: A) Natural selection B) Genetic advantage C) Genetic cost D) Selective advantage Ans: a ...
Absence of translationally selected synonymous codon usage
... (Covacci et al., 1997) ; these genes were analysed separately. Thirteen genes occur in insertion element sequences and were excluded because these can have compositional properties quite different from chromosomal genes. A further 509 genes had been identified only on the basis of being ORFs with co ...
... (Covacci et al., 1997) ; these genes were analysed separately. Thirteen genes occur in insertion element sequences and were excluded because these can have compositional properties quite different from chromosomal genes. A further 509 genes had been identified only on the basis of being ORFs with co ...
Polymerase Chain Reaction In Ophthalmology
... Real time PCR and other nucleic acid amplification tests have been proven to be most sensitive tools in the diagnosis of chlamydia infections. These tests can detect as few as one organism per assay, on the other hand presence of 10 organisms are required in sample for detection by conventional meth ...
... Real time PCR and other nucleic acid amplification tests have been proven to be most sensitive tools in the diagnosis of chlamydia infections. These tests can detect as few as one organism per assay, on the other hand presence of 10 organisms are required in sample for detection by conventional meth ...
Careful risk assessment needed to evaluate transgenic fish
... production. Ironically, in addition to being the taxonomic group with the most transgenic species, aquatic organisms are also the most likely group to present environmental concerns if accidentally released into the environment. Unlike most other agricultural species, fish are both difficult to contai ...
... production. Ironically, in addition to being the taxonomic group with the most transgenic species, aquatic organisms are also the most likely group to present environmental concerns if accidentally released into the environment. Unlike most other agricultural species, fish are both difficult to contai ...
1q21 microdeletions
... family. We know that if one person is mildly affected, others may be more severely and obviously affected. In families where both parents have been tested and have normal chromosomes, the possibility of having another child with a 1q21.1 microdeletion is almost certainly no higher than anyone else’s ...
... family. We know that if one person is mildly affected, others may be more severely and obviously affected. In families where both parents have been tested and have normal chromosomes, the possibility of having another child with a 1q21.1 microdeletion is almost certainly no higher than anyone else’s ...
1q21 microdeletions
... million base pairs, or one so-called megabase (Mb) of DNA. Base pairs are the chemicals in DNA that form the ends of the ‘rungs’ of its ladder-like structure. Chromosome 1 has around 247 Mb in total and band 1q21.1 alone contains around 5.4 Mb. In a class 1 deletion, DNA is typically missing between ...
... million base pairs, or one so-called megabase (Mb) of DNA. Base pairs are the chemicals in DNA that form the ends of the ‘rungs’ of its ladder-like structure. Chromosome 1 has around 247 Mb in total and band 1q21.1 alone contains around 5.4 Mb. In a class 1 deletion, DNA is typically missing between ...
Chance and Necessity in Arthur Peacocke`s Scientific Work
... (Complete proceedings will appear in the March 2008 issue of Zygon.) ...
... (Complete proceedings will appear in the March 2008 issue of Zygon.) ...
Are You suprised ?
... is determined by the sequence of nucleotides in a gene. A change in the DNA nucleotide sequence (mutation) of a gene that codes for a protein may result in a change in the amino-acid sequence of the protein. Biochemical evidence of evolution compares favorably with structural evidence of evolution. ...
... is determined by the sequence of nucleotides in a gene. A change in the DNA nucleotide sequence (mutation) of a gene that codes for a protein may result in a change in the amino-acid sequence of the protein. Biochemical evidence of evolution compares favorably with structural evidence of evolution. ...
Dynamic Changes in Aromatic Hydrocarbon Associated Catabolic
... Aerobic pathways of aromatic hydrocarbon degradation employ oxygen as a terminal electron acceptor, and mono- and dioxygenase enzymes, to cleave the benzene ring which results in a loss of aromaticity [4]. Biodegradation pathways of aromatic hydrocarbons have been intensively investigated, much is k ...
... Aerobic pathways of aromatic hydrocarbon degradation employ oxygen as a terminal electron acceptor, and mono- and dioxygenase enzymes, to cleave the benzene ring which results in a loss of aromaticity [4]. Biodegradation pathways of aromatic hydrocarbons have been intensively investigated, much is k ...
Properties of Mitotic and Meiotic Recombination in the
... array, and heterozygous for markers flanking the array, we measured inter-homolog recombination and intra-/sister-chromatid exchange in the CUP1 locus. The rate of intra-/sister chromatid recombination exceeded the rate of inter-homolog recombination by more than ten-fold. Loss of the Rad51 and Rad5 ...
... array, and heterozygous for markers flanking the array, we measured inter-homolog recombination and intra-/sister-chromatid exchange in the CUP1 locus. The rate of intra-/sister chromatid recombination exceeded the rate of inter-homolog recombination by more than ten-fold. Loss of the Rad51 and Rad5 ...
NOVEL SPERM-SPECIFIC GLYCOLYTIC ISOZYMES GENERATED
... spliced exon in Aldoa_v2. Expression of all three isozymes was restricted to the male germline and was regulated at transcriptional and translational levels. Both ALDOART1 and ALDOA_V2 are tightly bound to the fibrous sheath and have unique N-terminal extensions that may mediate this binding. ALDOA_ ...
... spliced exon in Aldoa_v2. Expression of all three isozymes was restricted to the male germline and was regulated at transcriptional and translational levels. Both ALDOART1 and ALDOA_V2 are tightly bound to the fibrous sheath and have unique N-terminal extensions that may mediate this binding. ALDOA_ ...
Molecular Evolution of Overlapping Genes
... overlap on either the same strand or on the opposite strand. The sequence interdependence between two overlapping coding regions adds complexity to almost all molecular evolution analyses. Here, I use a comparative-genomic approach aimed at resolving several open questions concerning the evolution o ...
... overlap on either the same strand or on the opposite strand. The sequence interdependence between two overlapping coding regions adds complexity to almost all molecular evolution analyses. Here, I use a comparative-genomic approach aimed at resolving several open questions concerning the evolution o ...
Methods of Human Heredity Study
... become heterochromatic only at certain stages. For instance, in female humans one X-chromosome is inactivated or becomes heterochromatic only facultatively. It is also established that DNA in heterochromatic regions replicates at a time different than the DNA in euchromatic regions, and that genes i ...
... become heterochromatic only at certain stages. For instance, in female humans one X-chromosome is inactivated or becomes heterochromatic only facultatively. It is also established that DNA in heterochromatic regions replicates at a time different than the DNA in euchromatic regions, and that genes i ...
Molecular Identification of Nematodes Manual
... other with the DNA sequence to be amplified located in between), and they each have optimum melting temperatures ™. *A Tm for a primer can be found by using this “quick ‘n’ dirty” formula: Tm is approximately equal to 2oC (A + T) + 4oC (G + C). For example, if your 20-mer primer has 5 A’s, 7 C’s, 6 ...
... other with the DNA sequence to be amplified located in between), and they each have optimum melting temperatures ™. *A Tm for a primer can be found by using this “quick ‘n’ dirty” formula: Tm is approximately equal to 2oC (A + T) + 4oC (G + C). For example, if your 20-mer primer has 5 A’s, 7 C’s, 6 ...
alignable - gobics.de: Department of Bioinformatics
... Fragment-based alignment approach (DIALIGN) useful for alignment of genomic sequences. ...
... Fragment-based alignment approach (DIALIGN) useful for alignment of genomic sequences. ...
AraC Protein, Regulation of the L-arabinose Operon in Escherichia
... problems, and because they most obviously share homologous DNA-binding domains, these domains were expected to be insoluble. It was a surprise, however, to discover that the AraC DNA-binding domain itself is soluble, well behaved biochemically, and can be purified readily (Timmes et al., 2004). Prot ...
... problems, and because they most obviously share homologous DNA-binding domains, these domains were expected to be insoluble. It was a surprise, however, to discover that the AraC DNA-binding domain itself is soluble, well behaved biochemically, and can be purified readily (Timmes et al., 2004). Prot ...
STRIVE Report Series No.65
... Although every effort has been made to ensure the accuracy of the material contained in this publication, complete accuracy cannot be guaranteed. Neither the Environmental Protection Agency nor the author(s) accept any responsibility whatsoever for loss or damage occasioned or claimed to have been o ...
... Although every effort has been made to ensure the accuracy of the material contained in this publication, complete accuracy cannot be guaranteed. Neither the Environmental Protection Agency nor the author(s) accept any responsibility whatsoever for loss or damage occasioned or claimed to have been o ...
Patent constraints
... 1. An isolated nucleic acid molecule comprising a nucleotide sequence which (i) encodes a protein or polypeptide comprising an amino acid sequence of SEQ. ID. No. 3, SEQ. ID. No. 5, SEQ. ID. No. 7, SEQ. ID. No. 9, SEQ. ID. No. 11, SEQ. ID. No. 13, SEQ. ID. No. 15, SEQ. ID. No. 17, SEQ. ID. No. 20, S ...
... 1. An isolated nucleic acid molecule comprising a nucleotide sequence which (i) encodes a protein or polypeptide comprising an amino acid sequence of SEQ. ID. No. 3, SEQ. ID. No. 5, SEQ. ID. No. 7, SEQ. ID. No. 9, SEQ. ID. No. 11, SEQ. ID. No. 13, SEQ. ID. No. 15, SEQ. ID. No. 17, SEQ. ID. No. 20, S ...
