Pathogen Response Genes Mediate Caenorhabditis elegans Innate
... defense against infection, serving to detect pathogens and initiate a neutralizing response (Shivers et al. 2008; Akira et al. 2006). However, recent studies suggest a greater specificity than was initially anticipated, in that various gene classes such as lysozymes, CUB-domains, lectins, ShK-like t ...
... defense against infection, serving to detect pathogens and initiate a neutralizing response (Shivers et al. 2008; Akira et al. 2006). However, recent studies suggest a greater specificity than was initially anticipated, in that various gene classes such as lysozymes, CUB-domains, lectins, ShK-like t ...
Nucleic Acids - Farmasi Unand
... as miniband units, which form the basis of the structures of chromosomes. Chromosomes are the structures that form duplicates during cell division in order to transfer the genetic information of the old cell to the two ...
... as miniband units, which form the basis of the structures of chromosomes. Chromosomes are the structures that form duplicates during cell division in order to transfer the genetic information of the old cell to the two ...
Microsoft Word
... for the apo form of human eIF4E by multidimensional NMR [47] and for the murine factor by hydrogendeuterium exchange combined with electrospray mass spectrometry [48]. The secondary elements were preserved in apo eIF4E while the loops exhibited mobility on the ns - ps time scale that became abrogat ...
... for the apo form of human eIF4E by multidimensional NMR [47] and for the murine factor by hydrogendeuterium exchange combined with electrospray mass spectrometry [48]. The secondary elements were preserved in apo eIF4E while the loops exhibited mobility on the ns - ps time scale that became abrogat ...
Targeted gene inactivation in Clostridium phytofermentans shows
... but had lost the ability to degrade crystalline cellulose. mRNA expression supports that cphy3367 is among the most highly up-regulated CAZy genes during growth on cellulose. These findings reveal a central role played by Cphy3367 in cellulose degradation. Generally, these results show that targeted ...
... but had lost the ability to degrade crystalline cellulose. mRNA expression supports that cphy3367 is among the most highly up-regulated CAZy genes during growth on cellulose. These findings reveal a central role played by Cphy3367 in cellulose degradation. Generally, these results show that targeted ...
DRACULA2 is a dynamic nucleoporin with a role in
... four dra2-1×Col-0 backcrosses (Fig. S4D). These results suggested that the genomic Col-0 background (very likely near the DRA2 locus) strongly modifies the mutant phenotype caused by DRA2 loss of function. DRA2 encodes an NUP of 1041 amino acids, with a molecular mass of ∼105 kDa, and that contains ...
... four dra2-1×Col-0 backcrosses (Fig. S4D). These results suggested that the genomic Col-0 background (very likely near the DRA2 locus) strongly modifies the mutant phenotype caused by DRA2 loss of function. DRA2 encodes an NUP of 1041 amino acids, with a molecular mass of ∼105 kDa, and that contains ...
SMN1
... According to one hypothesis, reduced SMN levels result in reduced assembly of Sm proteins onto snRNA. This unevenly alters the levels of specific endogenous snRNPs, such as those used to splice minor introns (particularly U11) from pre-mRNA. It remains to be determined what the downstream target gen ...
... According to one hypothesis, reduced SMN levels result in reduced assembly of Sm proteins onto snRNA. This unevenly alters the levels of specific endogenous snRNPs, such as those used to splice minor introns (particularly U11) from pre-mRNA. It remains to be determined what the downstream target gen ...
Translational control of regA, a key gene controlling
... 3⬘ end with which they could be inserted in the pVcRegA1 plasmid. A DNA fragment consisting of five copies of a BamHI linker sequence was used previously to generate a stable hairpin that blocked ribosomal scanning but not ribosomal shunting (Yueh and Schneider, 1996; Yueh and Schneider, 2000). So w ...
... 3⬘ end with which they could be inserted in the pVcRegA1 plasmid. A DNA fragment consisting of five copies of a BamHI linker sequence was used previously to generate a stable hairpin that blocked ribosomal scanning but not ribosomal shunting (Yueh and Schneider, 1996; Yueh and Schneider, 2000). So w ...
Antibiotics involved in Clostridium difficile
... genes encoding known, or putative, colonization factors: three adhesins, P47 (one of the two Slayer proteins), Cwp66 and Fbp68, and a protease, Cwp84. The conditions studied included hyperosmolarity, iron depletion and exposure to several antibiotics (ampicillin, clindamycin, ofloxacin, moxifloxacin ...
... genes encoding known, or putative, colonization factors: three adhesins, P47 (one of the two Slayer proteins), Cwp66 and Fbp68, and a protease, Cwp84. The conditions studied included hyperosmolarity, iron depletion and exposure to several antibiotics (ampicillin, clindamycin, ofloxacin, moxifloxacin ...
Slide 1
... • Goal is to segment the genome into sub-classes. In each case, the tools identify certain data properties that subsets of the genome. Based on the groupings, the presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the classes established. ...
... • Goal is to segment the genome into sub-classes. In each case, the tools identify certain data properties that subsets of the genome. Based on the groupings, the presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the classes established. ...
In-situ Protocol for larval/pupal/adult tissues
... This part of the protocol covers fluorescent signal detection. It is not necessary to be RNase free post-hybridization, so all block and wash buffers may be made without following RNasefree technique. All fluorescence antibody steps should be carried out in a humidified chamber to prevent evaporatio ...
... This part of the protocol covers fluorescent signal detection. It is not necessary to be RNase free post-hybridization, so all block and wash buffers may be made without following RNasefree technique. All fluorescence antibody steps should be carried out in a humidified chamber to prevent evaporatio ...
pdf
... These include structural genes for the viral coat and enzymes for cell lysis. Figure 4.3.5. Transcription and translation of immediate early genes. ...
... These include structural genes for the viral coat and enzymes for cell lysis. Figure 4.3.5. Transcription and translation of immediate early genes. ...
PDF
... The H19 gene was cloned 20 years ago (Pachnis et al., 1988) and was one of the first imprinted genes to be identified. Genomic imprinting is an epigenetic mechanism that leads to parent-of-origin specific monoallelic expression. Thus, H19 is expressed from the maternal allele in mouse and human (Bar ...
... The H19 gene was cloned 20 years ago (Pachnis et al., 1988) and was one of the first imprinted genes to be identified. Genomic imprinting is an epigenetic mechanism that leads to parent-of-origin specific monoallelic expression. Thus, H19 is expressed from the maternal allele in mouse and human (Bar ...
A Plastid in the Making: Evidence for a Second
... Figure 1. a. Phylogenetic evidence for an independent cyanobacterial origin of the photosynthetic organelle of Paulinella chromatophora, significantly separated from the plastid lineage. The maximum-likelihood tree (GTR+I+G; I ¼ 0:2661; G ¼ 0:7513) was based on almost-complete rDNA operon sequences ...
... Figure 1. a. Phylogenetic evidence for an independent cyanobacterial origin of the photosynthetic organelle of Paulinella chromatophora, significantly separated from the plastid lineage. The maximum-likelihood tree (GTR+I+G; I ¼ 0:2661; G ¼ 0:7513) was based on almost-complete rDNA operon sequences ...
Plants` Epigenetic Secrets
... There are three different types of DNA methylation in plants: CG, CHH (where H is any base except G), and CHG. In Arabidopsis, CG methylation is found on some genes, but primarily on repeat sequences that make up transposons, as well as other repeat sequences in the genome. CHH methylation is found ...
... There are three different types of DNA methylation in plants: CG, CHH (where H is any base except G), and CHG. In Arabidopsis, CG methylation is found on some genes, but primarily on repeat sequences that make up transposons, as well as other repeat sequences in the genome. CHH methylation is found ...
Genes Practice Questions
... 83 If there are only 20 amino acids used in the process of translation, explain the existence of thousands of different types of proteins in living organisms. ...
... 83 If there are only 20 amino acids used in the process of translation, explain the existence of thousands of different types of proteins in living organisms. ...
T-box-mediated control of the anabolic proline biosynthetic genes of
... Vitreschak et al., 2008; Wels et al., 2008; Winkler, 2007). Tbox systems are RNA-based regulatory switches (Henkin, 2008) that are used in many Gram-positive microorganisms to regulate the expression of aminoacyl-tRNA synthetase genes and of genes involved in amino acid ...
... Vitreschak et al., 2008; Wels et al., 2008; Winkler, 2007). Tbox systems are RNA-based regulatory switches (Henkin, 2008) that are used in many Gram-positive microorganisms to regulate the expression of aminoacyl-tRNA synthetase genes and of genes involved in amino acid ...
The ara Operon - University of Pennsylvania
... This model assumes that two molecules of AraC are always joined together as a dimer. Further, this dimer can exist in two different states: active (P1) and inactive (P2). When arabinose is absent, AraC dimer is in the P1 state but when arabinose is present, it can react with AraC and change its conf ...
... This model assumes that two molecules of AraC are always joined together as a dimer. Further, this dimer can exist in two different states: active (P1) and inactive (P2). When arabinose is absent, AraC dimer is in the P1 state but when arabinose is present, it can react with AraC and change its conf ...
iron-regulatory protein 1
... been previously described by Moeder et al. [20] and was named KO-661 [20]. Lines homozygous for the disruption were isolated, and used for further studies. When the mutants were grown in a greenhouse, or in hydroponic cultures under controlled conditions, they displayed no macroscopic phenotype. Fur ...
... been previously described by Moeder et al. [20] and was named KO-661 [20]. Lines homozygous for the disruption were isolated, and used for further studies. When the mutants were grown in a greenhouse, or in hydroponic cultures under controlled conditions, they displayed no macroscopic phenotype. Fur ...
network - bioinf leipzig
... Regulatory interactions can also be inferred directly from data = reverse engineering of biological pathways/networks from data. In the example above time-series expression data61is used to infer a directed and signed graph based on delayed correlations. ...
... Regulatory interactions can also be inferred directly from data = reverse engineering of biological pathways/networks from data. In the example above time-series expression data61is used to infer a directed and signed graph based on delayed correlations. ...
Comparison of Statistical Models for Affymetrix GeneChip
... Model-based estimators are superior to simple averaging Full model superior to reduced this does not necessarily mean that the mismatch probes are a good idea - but if they are present we should use them we have demonstrated this using both analytic considerations and experimental data a carefully d ...
... Model-based estimators are superior to simple averaging Full model superior to reduced this does not necessarily mean that the mismatch probes are a good idea - but if they are present we should use them we have demonstrated this using both analytic considerations and experimental data a carefully d ...
Resources for the map-based cloning of tga1
... (2002, Genetics 160:765-777) to test for a reduction in polymorphism using the combined promoter and exon 1 sequences. For this analysis, the neutral distribution was calculated with the following parameters estimated from the teosinte data: Rn=0.1205, =0.02626 for the promoter region, and =0.0133 ...
... (2002, Genetics 160:765-777) to test for a reduction in polymorphism using the combined promoter and exon 1 sequences. For this analysis, the neutral distribution was calculated with the following parameters estimated from the teosinte data: Rn=0.1205, =0.02626 for the promoter region, and =0.0133 ...
Editorial Noncoding RNAs
... in the life sciences that have led to major paradigm shifts. An example is the emerging appreciation of the critical role of noncoding RNAs in a broad range of physiological and pathological processes. One such class of noncoding RNAs, the microRNAs (miRNAs), controls intricate networks of gene expr ...
... in the life sciences that have led to major paradigm shifts. An example is the emerging appreciation of the critical role of noncoding RNAs in a broad range of physiological and pathological processes. One such class of noncoding RNAs, the microRNAs (miRNAs), controls intricate networks of gene expr ...
Oligonucleotide Cross-Linking
... Oxidative Cross-Linking The phenylselenide (PhSe) group in nucleoside analogues has been described as a cross-linker by generating methyl radicals induced by photo-irradiation25 and also, interestingly, by an oxidative mechanism using sodium periodate.26 Work has been carried out in both duplex and ...
... Oxidative Cross-Linking The phenylselenide (PhSe) group in nucleoside analogues has been described as a cross-linker by generating methyl radicals induced by photo-irradiation25 and also, interestingly, by an oxidative mechanism using sodium periodate.26 Work has been carried out in both duplex and ...
Comparison of conserved structural and regulatory domains within
... morphological and physiological diversity is mirrored by extensive genetic variability, cyanobacterial genomes ranging in mean DNA base composition from 32 to 71 mol % GjC (Herdman et al., 1979b ; M. Herdman & R. Rippka, unpublished) and in complexity from 2n0 to 13n2 Mbp (Herdman et al., 1979a ; M. ...
... morphological and physiological diversity is mirrored by extensive genetic variability, cyanobacterial genomes ranging in mean DNA base composition from 32 to 71 mol % GjC (Herdman et al., 1979b ; M. Herdman & R. Rippka, unpublished) and in complexity from 2n0 to 13n2 Mbp (Herdman et al., 1979a ; M. ...
... expressed in early embryos, but the paternal copy is activated in conjunction with the acquisition of a tissuerestricted expression pattern established by mid gestation, that is, in the heart, kidney and brain [7]. Thus, the Kcnq1 domain illustrates the regulatory challenges that must be met in a co ...
Non-coding RNA
A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.