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No Slide Title - McGraw Hill Higher Education
No Slide Title - McGraw Hill Higher Education

... • Rhythm of peristalsis controlled by pacemaker cells in longitudinal muscle layer – gentle ripple of contraction every 20 seconds churns and mixes food with gastric juice – stronger contraction at pyloric region; ejects 3 ml – typical meal emptied from stomach in 4 hours ...
GI tract
GI tract

Colon - Amazon Web Services
Colon - Amazon Web Services

... – Sphincters: internal (involuntary), external (voluntary) ...
Continuing Education Independent Study Series
Continuing Education Independent Study Series

... The functions of the large intestine are completion of absorption, production of some vitamins, formation of feces, and expulsion of feces. The large intestine is about 5 feet in length and divided into segments. The segments are the cecum, right ascending colon, transverse colon. left descending co ...
Human Anatomy & Physiology II
Human Anatomy & Physiology II

Unit 3 Lecture 9
Unit 3 Lecture 9

... Liver The liver is the heaviest gland in the body. It contains two lobes (the right lobe includes quadrate and caudate lobes). The right and left lobes are separated by falciform ligament. The liver is made up of lobules which are the functional units of the liver. The lobules contain hepatocytes (l ...
Biology 11 - Human Anatomy Lecture
Biology 11 - Human Anatomy Lecture

Digestion and Absorption of Nutrients
Digestion and Absorption of Nutrients

Preview Sample 2
Preview Sample 2

... b. the lipoproteins that transport lipids from the intestinal cells into the body. c. a cluster of lipids associated with proteins that serves as a transport vehicle for lipids in the lymph and blood. d. the type of lipoproteins made primarily by liver cells to transport lipids to various tissues in ...
VIII. Digestion
VIII. Digestion

... A. Pancreatic juice contains the protein-digesting enzymes trypsin, chymotrypsin, among others. B. The brush border contains digestive enzymes that help to complete the digestion of proteins into amino acids. ...
Small intestine and pancreas
Small intestine and pancreas

... 6) Once in the small intestine the bile salts break down the large fat droplets into smaller drops (just like dish soap) = emulsification 7) This leaves a larger surface for pancreatic lipase to get at the fat ...
The Chemical Digestion of Food - Toronto District Christian High
The Chemical Digestion of Food - Toronto District Christian High

Chapter 23: The Digestive System
Chapter 23: The Digestive System

... The Digestive System The digestive system is responsible for the food-processing activities of ingestion, digestion, absorption, and elimination of feces. Because of the external openings, you will be presented with the unique concept that food “inside” the alimentary canal (the GI tract) is actuall ...
Section 3
Section 3

OTHER CF DIGESTIVE SYSTEM PROBLEMS
OTHER CF DIGESTIVE SYSTEM PROBLEMS

Development of the GI tract
Development of the GI tract

The Human Digestive System
The Human Digestive System

... reach the intestine through small tubes called ducts. The chemical produced by the liver is called bile, and it may be stored in the gallbladder between meals. ...
Digestive System Notes
Digestive System Notes

...  The secretory cells release a mixture of enzymes known as pancreatic juice into the duct  The ducts from all the acini drain into the pancreatic duct, which fuses with the common bile duct before entering the small intestine  Scattered among the acini are clusters of endocrine cells called the i ...
Digestion and Nutrition
Digestion and Nutrition

... radiating from a central vein. ...
Anatomy and Physiology The Digestive System
Anatomy and Physiology The Digestive System

... • an immune (allergic) reaction to gluten, a protein present in cereal grains (wheat, barley and rye) • The lining of the small intestine is affected, decreasing the amount of surface available for the absorption of nutrients. Main Symptoms: • weight loss, bloating, stomach pain after eating, someti ...
Unit 10 Digestive
Unit 10 Digestive

... Can occur in all areas of the digestive system Can be malignant or benign Colorectal Cancer – 3rd most common cause of cancer for both males and females – Overall mortality rate is over 60% – Factors contributing to colorectal cancer include genetic predisposition, diet high in fat, protein, insuffi ...
Lecture Outline ()
Lecture Outline ()

... hepatic duct to form the bile duct • Duct of pancreas and bile duct combine to form hepatopancreatic ampulla emptying into the duodenum at the major duodenal papilla – sphincter of Oddi (hepatopancreatic sphincter) regulates release of bile & pancreatic juice ...
What do we digest? What is food made up of?
What do we digest? What is food made up of?

... What is the pH of the small intestine? Generally it is around neutral, although the first section will be slightly acidic (6 – 6.5) and the ...
The structure of Kidney
The structure of Kidney

Lecture 1
Lecture 1

... Absorption of Nutrients by the Stomach ...
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Hepatotoxicity



Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents, when taken in overdoses and sometimes even when introduced within therapeutic ranges, may injure the organ. Other chemical agents, such as those used in laboratories and industries, natural chemicals (e.g., microcystins) and herbal remedies can also induce hepatotoxicity. Chemicals that cause liver injury are called hepatotoxins.More than 900 drugs have been implicated in causing liver injury and it is the most common reason for a drug to be withdrawn from the market. Hepatotoxicity and drug-induced liver injury also account for a substantial number of compound failures, highlighting the need for drug screening assays, such as stem cell-derived hepatocyte-like cells, that are capable of detecting toxicity early in the drug development process. Chemicals often cause subclinical injury to the liver, which manifests only as abnormal liver enzyme tests. Drug-induced liver injury is responsible for 5% of all hospital admissions and 50% of all acute liver failures.
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