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mic.sgmjournals.org
mic.sgmjournals.org

... was observed and we focused our attention on lactate synthesis. Lactate synthesis was due to the ldh-encoded L-lactate dehydrogenase (Ldh). Features of Ldh activity and ldh transcription were analysed. The ldh gene was shown to be regulated at the transcriptional level by SugR, a pleiotropic transcr ...
Maximum likelihood methods for detecting adaptive evolution after
Maximum likelihood methods for detecting adaptive evolution after

... 1999; Bielawski and Yang, 2001). Hence, the apparent period of relaxed selection following gene duplication (e.g., Lynch and Conery, 2000) might also reflect adaptive divergence of duplicate genes at just a subset of amino acid sites. Recent ML models of codon substitution relax the assumption of a ...
Bioinformatics Dr. Víctor Treviño  Pabellón Tec
Bioinformatics Dr. Víctor Treviño Pabellón Tec

... PRESENTACIONES DE PAPERS EN MARZO ...
Role for CCG-trinucleotide repeats in the pathogenesis of chronic
Role for CCG-trinucleotide repeats in the pathogenesis of chronic

... Chronic lymphocytic leukemia (CLL) is characterized by a clonal proliferation of mature B-lymphocytes increasing in incidence logarithmically with age in adults.1 Sporadic CLL may have a hereditary component because several studies report an elevated risk for hematologic malignancy2,3 and other canc ...
3- PARTE I Comparative cytogenetic mapping of Sox2 and
3- PARTE I Comparative cytogenetic mapping of Sox2 and

... groups (mammals, birds, fishes), they were not conserved as observed in mammals. Sox14 orthologs are highly diverged in non-mammal groups and Sox2 orthologs are more stable among all vertebrates. The analysis of the genomic blocks containing Sox genes suggest the genes observed in the region are evo ...
Binding of Hoechst with nucleic acids using fluorescence spectroscopy
Binding of Hoechst with nucleic acids using fluorescence spectroscopy

... Full understanding of the molecular mechanisms of action of heterocyclic antibiotics at low concentrations on DNA and RNA can optimize the use of these compounds and their analogues as medical drugs. Hoechst dyes 33342 and 33258 are closely related bisbenzimides. Hoechst 33258 is 2’-(4-hydroxyphenyl ...
unique features of the plant life cycle and their consequences
unique features of the plant life cycle and their consequences

... are masked in the heterozygous diploid individuals10. Despite its possible advantages, natural selection has favoured the reduction of the haploid phase in plants in three ways: the proportion of the total life cycle, physical size and the range of biological processes. Although there is great diver ...
htp Pseudomonas aeruginosa AMANDA SWANEPOEL
htp Pseudomonas aeruginosa AMANDA SWANEPOEL

... as those with cancer or AIDS and those suffering from cystic fibrosis and burns (Van Delden and Iglewski, 1998; Ramsey and Wozniak, 2005), but it has also been shown to infect plants and insects (Schroth et al., 1992; Rahme et al., 1995). The success of P. aeruginosa in colonizing these diverse envi ...
File
File

... red eye color. When two pure-breeding red strains 1 and 2 are intercrossed, the F1 is also red. However when the F1 is backcrossed to strain 1, the progeny show 3/4 red and 1/4 peach flies. The genotype of the strain 1 must have been A) p+/p+ ; s+/s+ B) p+/p ; s/s C) p/p ; s+/s+ D) p+/p ; s+/s * E) ...
cbb752-mg-spr09-bioinfo
cbb752-mg-spr09-bioinfo

... molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with ...
The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development 122, 1353-1362. pdf
The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development 122, 1353-1362. pdf

... hardened for 48 hours at 70°C. Sections (5 µm thick) were cut on a Reichard ultramicrotome, counterstained with 1% methylene blue, and mounted on microscope slides with Permount. Larvae were dissected in phosphate-buffered saline and fixed in either 1% glutaraldehyde or 2% formaldehyde for 4′,6′diam ...
Studies of codon usage and tRNA genes of 18 unicellular organisms
Studies of codon usage and tRNA genes of 18 unicellular organisms

... represents the total codon number, and X is the codon usage vector for a gene. To exclude effects of gene size, amino acid composition, and codon box number, codon frequency for the i(m)th codon x was calculated with ...
The Arabidopsis WAVY GROWTH 2 Protein Modulates Root
The Arabidopsis WAVY GROWTH 2 Protein Modulates Root

... entire main and distal elongation zones; there were no noticeable differences between roots of wild-type and wav2-1 (Figure 4). Next, we examined the sensitivity of roots to drugs that affect microtubules by measuring the root slanting angles on agar medium in the vertical position (Figure 5A). When ...
study
study

... [20]. This can lead to the accumulation of genes with different effects on males and females. It is thus expected that the vast majority of sexually dimorphic traits are due to differential expression of genes that are present in both sexes [21]. While carried by both males and females, such genes a ...
the genome of herpes simplex virus: structure, replication and
the genome of herpes simplex virus: structure, replication and

... cis-acting signals fo r D N A replication a n d processing There was some early evidence, from electron microscopic analyses of H SV D N A extracted from infected cells, that the virus genome might possess one or more specific sites at which replicative synthesis of D N A started (Friedmann et al. 1 ...
This article was published in an Elsevier journal. The attached copy
This article was published in an Elsevier journal. The attached copy

... Published by Elsevier B.V. Keywords: Varicella Zoster Virus; Bacterial artificial chromosome; Deletion mutagenesis; Bioluminescence ...
Gene Section SHC4 (SHC (Src homology 2 domain containing) family, member 4)
Gene Section SHC4 (SHC (Src homology 2 domain containing) family, member 4)

... the disease revealed that SHC4 expression is found in around 50% of the VGP and metastatic melanomas and not in nevi and RGP melanomas, thus suggesting a putative role for SHC4 as a prognostic marker. When SHC4 is ectopically overexpressed in RGP melanoma cells it can stimulate migration in vitro, w ...
A method for finding molecular signatures from gene expression data
A method for finding molecular signatures from gene expression data

... Provide insight into biological mechanisms and processes and have potential diagnostic use. However, searching for molecular signatures often done using a very diverse and ad-hoc methodology. ...
Genes for two multicopper proteins required for Fe(III) oxide
Genes for two multicopper proteins required for Fe(III) oxide

... chemostats and during growth on a microbial fuel cell anode. In contrast, ompC transcript levels increased at higher growth rates in chemostats and with increasing current production in fuel cells. Constant levels of Geobacter ompB transcripts were detected in groundwater during a field experiment i ...
Genome Biology - Institute for Applied Ecology
Genome Biology - Institute for Applied Ecology

... whether the positive correlation in the male is the result of the dosage compensation or results from another mechanism. To determine if these correlation patterns might suggest which sex possesses a compensation mechanism to adjust the dose of some Z genes, we modeled the effect of male-specific or ...
Organization of chromosomes in the interphase cell - UvA-DARE
Organization of chromosomes in the interphase cell - UvA-DARE

... A functional model of higher order organization of chromatin in chromosome territories is the interchromosomal domain (ICD) model (Cremer et al., 1993; Zirbel et al., 1993). This model postulates space between chromosome territories in which transport takes place and enzyme complexes are formed, thu ...
The complement C3 protein family in invertebrates
The complement C3 protein family in invertebrates

... Complement C3 plays a pivotal role in the innate immune system of mammals as the central component of the complement system essential for its activation mechanism and effecter function. C3 has a unique intra-chain thioester bond that is shared by some complement and non-complement proteins forming a ...
PowerPoint Slides - Evo-Ed
PowerPoint Slides - Evo-Ed

... • Investigations indicated that the cells in population #9 were able to import citrate from the medium. • This is unusual given that E. coli generally cannot import citrate in the oxic (aerobic) conditions present in the experiment. • Once citrate enters the E. coli cell, it can be metabolized in Ci ...
word
word

... Genetic and epigenetic regulators of the germ line Specification of primordial germ cells (PGCs) in mammals occurs according to the 'stem cell model' in which pluripotent stem cells give rise to both the PGCs and somatic cells in response to signaling molecules. Expression of a transcriptional repre ...
Full-Text PDF
Full-Text PDF

... after in vitro enzymatic reaction of ScTrm9-Trm112 on tRNAs purified from the trm9∆ yeast strain. Furthermore, several groups observed a drop in cm5 (s2 )U34 formation upon disruption of TRM9 or TRM112 genes [13,14,21]. In S. cerevisiae, this mcm5 (s2 )U34 tRNA modification confers susceptibility to ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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