Regulation of the C. elegans molt by pqn-47
... et al., 2001). Even though non-parasitic nematodes have not been observed to respond to exogenous ecdysone, it is known that cholesterol is required for molting in C. elegans (Entchev and Kurzchalia, 2005; Martin et al., 2010), suggesting that steroid hormones could be ligands for receptors involved ...
... et al., 2001). Even though non-parasitic nematodes have not been observed to respond to exogenous ecdysone, it is known that cholesterol is required for molting in C. elegans (Entchev and Kurzchalia, 2005; Martin et al., 2010), suggesting that steroid hormones could be ligands for receptors involved ...
Fungal cell wall chitinases and glucanases
... cell separation by the potent chitinase inhibitor demethylallosamidin. Parting of yeast cells during budding is therefore dependent upon hydrolysis of chitin joining mother and daughter. More recently, King & Butler (1998) demonstrated that disruption of CTS1 can also promote pseudohyphal growth. Th ...
... cell separation by the potent chitinase inhibitor demethylallosamidin. Parting of yeast cells during budding is therefore dependent upon hydrolysis of chitin joining mother and daughter. More recently, King & Butler (1998) demonstrated that disruption of CTS1 can also promote pseudohyphal growth. Th ...
Genome position and gene amplification | SpringerLink
... and rare sites (RFS), which appear only in certain individuals. The sites are further distinguished by agents used to induce expression, which include aphidicolin, bromo-deoxyuridine (BrdU), 5-azacytidine and distamycin A. Folate stress caused by methotrexate exposure also induces a group of rare fr ...
... and rare sites (RFS), which appear only in certain individuals. The sites are further distinguished by agents used to induce expression, which include aphidicolin, bromo-deoxyuridine (BrdU), 5-azacytidine and distamycin A. Folate stress caused by methotrexate exposure also induces a group of rare fr ...
Aberrant DNA methylation in cancer: potential clinical
... DNA methylation, the addition of a methyl group to the carbon-5 position of cytosine residues, is the only common covalent modification of human DNA and occurs almost exclusively at cytosines that are followed immediately by a guanine (so-called CpG dinucleotides). The bulk of the genome displays a ...
... DNA methylation, the addition of a methyl group to the carbon-5 position of cytosine residues, is the only common covalent modification of human DNA and occurs almost exclusively at cytosines that are followed immediately by a guanine (so-called CpG dinucleotides). The bulk of the genome displays a ...
Fungal cell wall chitinases and glucanases
... the Cts1p chitinase of Co. immitis had no effect on growth or morphogenesis in these organisms (Reichard et al., 2000; Jaques et al., 2003). It is possible that related enzymes in A. fumigatus and Co. immitis compensate for the loss of ChiB1p or Cts1p. Alternatively, these secreted enzymes may not h ...
... the Cts1p chitinase of Co. immitis had no effect on growth or morphogenesis in these organisms (Reichard et al., 2000; Jaques et al., 2003). It is possible that related enzymes in A. fumigatus and Co. immitis compensate for the loss of ChiB1p or Cts1p. Alternatively, these secreted enzymes may not h ...
GENE-CBR - Indiana University School of Informatics
... an scanner and the associated software perform various forms of image analysis to measure and report raw gene expression values the scanned intensities show how active the genes represented by the ESTs are in the cell: • strong fluorescence indicates that the gene is very active in the cell • no flu ...
... an scanner and the associated software perform various forms of image analysis to measure and report raw gene expression values the scanned intensities show how active the genes represented by the ESTs are in the cell: • strong fluorescence indicates that the gene is very active in the cell • no flu ...
A selfish origin for recombination
... population genetics models have emphasized the role of modifier genes (for a review see Feldman et al., 1996) on the evolution of recombination, that is they have considered the evolution of recombination at a certain site as something imposed by another locus at a different position. This is of cour ...
... population genetics models have emphasized the role of modifier genes (for a review see Feldman et al., 1996) on the evolution of recombination, that is they have considered the evolution of recombination at a certain site as something imposed by another locus at a different position. This is of cour ...
View/Open
... XY placentas being significantly larger than XX placentas and that such differences are independent of androgen effects [37]. Although the possession of one X chromosome rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattl ...
... XY placentas being significantly larger than XX placentas and that such differences are independent of androgen effects [37]. Although the possession of one X chromosome rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattl ...
Preparation of recombinant proteins in milk to improve human and
... fact that only a part of the gene regulatory elements is known. This leads experimenters to associate non-compatible elements when they construct their genes. A few general rules have emerged to enhance the chance of obtaining a reliable expression of transgenes [8]. The addition of insulators is on ...
... fact that only a part of the gene regulatory elements is known. This leads experimenters to associate non-compatible elements when they construct their genes. A few general rules have emerged to enhance the chance of obtaining a reliable expression of transgenes [8]. The addition of insulators is on ...
ADP Ribosylation Factor is an Essential Protein in Saccharomyces cerevisiae and is Encoded by Two Genes.
... conserved, possibly explaining the failure to identify ARF2 in the experiments in which ARFI was originally cloned (39). The predicted ARF2 protein is identical in length to the ARF1 protein and 96% identical in protein sequence, differing at only 7 of 181 residues (Fig. 1). Most of these seven diff ...
... conserved, possibly explaining the failure to identify ARF2 in the experiments in which ARFI was originally cloned (39). The predicted ARF2 protein is identical in length to the ARF1 protein and 96% identical in protein sequence, differing at only 7 of 181 residues (Fig. 1). Most of these seven diff ...
The 2R hypothesis and the human genome sequence
... loci until disomic inheritance is established (Ohno, 1970). This is important for our interpretation of what a paleopolyploid genome should look like because one of the properties we test in assessing genome duplication is the synchronicity of divergence of duplicated loci. Depending on the manner a ...
... loci until disomic inheritance is established (Ohno, 1970). This is important for our interpretation of what a paleopolyploid genome should look like because one of the properties we test in assessing genome duplication is the synchronicity of divergence of duplicated loci. Depending on the manner a ...
Genetics of CO2 fixation in the chemoautotroph Alcaligenes eutrophus
... enzymes is dispensable in heterotrophically growing cells. Two lines of evidence support this conclusion: (i) the cfx genes, represented by the RuBisCO and PRK genes, are fully repressed in pyruvate-grown cells ([5], see Table 1); (ii) a plasmid-free Cfx- mutant with the cfx genes inactivated by Tn5 ...
... enzymes is dispensable in heterotrophically growing cells. Two lines of evidence support this conclusion: (i) the cfx genes, represented by the RuBisCO and PRK genes, are fully repressed in pyruvate-grown cells ([5], see Table 1); (ii) a plasmid-free Cfx- mutant with the cfx genes inactivated by Tn5 ...
Sex reversal: deletion mapping the male
... unpubl.) It is therefore not possible to construct a genetic linkage map of the Y chromosome from recombination frequencies among markers. However, the natural occurrence of a wide variety of structural abnormalities of the Y chromosome suggests the possibility of constructing a deletion map. Indeed ...
... unpubl.) It is therefore not possible to construct a genetic linkage map of the Y chromosome from recombination frequencies among markers. However, the natural occurrence of a wide variety of structural abnormalities of the Y chromosome suggests the possibility of constructing a deletion map. Indeed ...
生物信息学主要英文术语及释义
... state of a hid-den Markov model (representing one column of a multiple sequence alignment of proteins), based on prior distributions found in conserved protein domains (blocks). Distance in sequence analysis（序列距离） The number of observed changes in an optimal alignment of two sequences, usually not c ...
... state of a hid-den Markov model (representing one column of a multiple sequence alignment of proteins), based on prior distributions found in conserved protein domains (blocks). Distance in sequence analysis（序列距离） The number of observed changes in an optimal alignment of two sequences, usually not c ...
Genes for Cognitive Function: Developments on the X
... Figure 1 A flow diagram of the current approaches and resources available for mapping and identification of MRX genes. Currently two bags of resources are widely used, MRX families (large, lod>2, and small lod<2) and individual patients with X aberrations. Undoubtedly new technologies will play a ma ...
... Figure 1 A flow diagram of the current approaches and resources available for mapping and identification of MRX genes. Currently two bags of resources are widely used, MRX families (large, lod>2, and small lod<2) and individual patients with X aberrations. Undoubtedly new technologies will play a ma ...
Echinomycin binding to alternating AT
... modification of CCCG, CCGC and CGGC. For CCCG the CpG step will be occupied by the ligand under all conditions and result in strong reaction at the first adenine (CGA) on the 3'-side. The neighbour exclusion principle will forbid drug binding at the first ApT, but the second ApT is in the correct po ...
... modification of CCCG, CCGC and CGGC. For CCCG the CpG step will be occupied by the ligand under all conditions and result in strong reaction at the first adenine (CGA) on the 3'-side. The neighbour exclusion principle will forbid drug binding at the first ApT, but the second ApT is in the correct po ...
Mef2 gene expression marks the cardiac and skeletal muscle
... MEF2 DNA-binding activity is also present in neonatal cardiac myocytes, indicating that MEF2 expression can be controlled independently of the skeletal muscle bHLH proteins (Zhu et al., 1991; Yu et al., 1992; Navankasattusas et al., 1992; Ianello et al., 1991). The majority of cardiac gene control r ...
... MEF2 DNA-binding activity is also present in neonatal cardiac myocytes, indicating that MEF2 expression can be controlled independently of the skeletal muscle bHLH proteins (Zhu et al., 1991; Yu et al., 1992; Navankasattusas et al., 1992; Ianello et al., 1991). The majority of cardiac gene control r ...
Promega Notes 49: Firefly Luciferase Engineered for Improved
... encoded amino acid sequence. We also removed three palindromic sequences which could spuriously affect expression (22bp, 18bp, and 16bp, each with one mismatch). iii) Codon usage. In general, codon usage presumably reflects the availability of tRNA isoforms in different organisms; efficiently expres ...
... encoded amino acid sequence. We also removed three palindromic sequences which could spuriously affect expression (22bp, 18bp, and 16bp, each with one mismatch). iii) Codon usage. In general, codon usage presumably reflects the availability of tRNA isoforms in different organisms; efficiently expres ...
Initiation of recombination suppression and PAR formation during
... species in the genus Tokudaia that has maintained the Y chromosome, probably through fusion with an autosome [16, 18]. The short and long arms of their X chromosome (Xp and Xq) consisted of autosome (neo-X) and ancestral X, respectively, and the X chromosome had a large centromeric heterochromatin ...
... species in the genus Tokudaia that has maintained the Y chromosome, probably through fusion with an autosome [16, 18]. The short and long arms of their X chromosome (Xp and Xq) consisted of autosome (neo-X) and ancestral X, respectively, and the X chromosome had a large centromeric heterochromatin ...
Transition Bias
... – they are less likely to disrupt RNA secondary structure than transversions. ...
... – they are less likely to disrupt RNA secondary structure than transversions. ...
Molecular Diagnostics 6
... Viability is not much critical for molecular testing DNA and especially RNA can be damaged in lysed or nonviable cells ...
... Viability is not much critical for molecular testing DNA and especially RNA can be damaged in lysed or nonviable cells ...
The Comparison of Transcriptomes Undergoing Waterlogging at the
... A total of 2994 overlapping genes between GH01 (4857) and ZS9 (4432) were identified (Appendix B). A comprehensive analysis of these 2994 genes based on GO terms (Table 2) revealed that 3 major categories, “transcription regulation”, “carbohydrate metabolism” and “transporter facilitation” were reve ...
... A total of 2994 overlapping genes between GH01 (4857) and ZS9 (4432) were identified (Appendix B). A comprehensive analysis of these 2994 genes based on GO terms (Table 2) revealed that 3 major categories, “transcription regulation”, “carbohydrate metabolism” and “transporter facilitation” were reve ...
Tools for Comparing Bacterial Genomes
... different story. This strictly anaerobic organism so efficiently produces methane that it is held responsible for virtually all biogenic methane. It can also oxidate CO to CO2 (Lessner et al., 2006). Strain C2A (the type strain of the species) was isolated from a marine sediment (Galagan et al., 200 ...
... different story. This strictly anaerobic organism so efficiently produces methane that it is held responsible for virtually all biogenic methane. It can also oxidate CO to CO2 (Lessner et al., 2006). Strain C2A (the type strain of the species) was isolated from a marine sediment (Galagan et al., 200 ...
Gene Loss and Evolutionary Rates Following Whole
... Out of 2,371 human genes with a clear orthology relation to mapped Tetraodon genes, 364 have a phylogenetic profile typical of the WGD in Tetraodon (see Materials and Methods). This gives an estimate of 15% of gene pairs retained after the WGD, that is, loss of one of the paralogs in 85% of pairs. T ...
... Out of 2,371 human genes with a clear orthology relation to mapped Tetraodon genes, 364 have a phylogenetic profile typical of the WGD in Tetraodon (see Materials and Methods). This gives an estimate of 15% of gene pairs retained after the WGD, that is, loss of one of the paralogs in 85% of pairs. T ...
Relationships Between RNA Polymerase II Activity and Spt
... yeast genome and many of these exhibit modulation by many factors (Martens et al. 2004, 2005; Hainer et al. 2011; Bird et al. 2006). Furthermore, widespread antisense transcription is being revealed as a mechanism for shaping gene regulation in a number of ways, including transcription over promoter ...
... yeast genome and many of these exhibit modulation by many factors (Martens et al. 2004, 2005; Hainer et al. 2011; Bird et al. 2006). Furthermore, widespread antisense transcription is being revealed as a mechanism for shaping gene regulation in a number of ways, including transcription over promoter ...