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Two groups of human herpesvirus 6 identified by sequence
Two groups of human herpesvirus 6 identified by sequence

... group A (U 1102) and group B (Z29) show in addition to extensive DNA cross-hybridization an identical genome structure, base composition and size. These are AT-rich, 162 kbp genomes bounded by direct terminal repeats (Martin et al., 1991; Lindquester & Pellett, 1991). In this study we investigated t ...
Cluster analysis
Cluster analysis

... A reliable and precise classification of tumours is essential for successful diagnosis and treatment of cancer. Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. In spite of recent progress, there are still uncertainties in diag ...
i3017e02
i3017e02

... • Domestic animal diversity is an integral part of the environment in a range of production systems. The loss of this diversity would increase instability and risk in these production systems and reduce their ability to respond to changes. Maintenance and development of adapted breeds are criticall ...
PDF
PDF

... regulators of dynamic chromatin transitions alter histone-DNA contacts in an ATP-dependent manner in order to incorporate core and linker histones into chromatin or to move nucleosomes on DNA. The nucleosome sliding factors CHRAC and ACF were purified from Drosophila embryos following assays for chr ...
What stay-green mutants tell us about nitrogen remobilization in leaf
What stay-green mutants tell us about nitrogen remobilization in leaf

... options and close in on the region of the genome that the stay-green locus occupies. As well as promiscuous alien recombination, there is a further experimental benefit of Lolium and Festuca for genetic analysis: a high degree of molecular polymorphism between the species and genera. This is reflect ...
CS790 – Introduction to Bioinformatics
CS790 – Introduction to Bioinformatics

... GCG-TIntro to Bioinformatics – Sequence Alignment ...
Analysis of Tetrads from the yeast Saccaromyces
Analysis of Tetrads from the yeast Saccaromyces

... When normally haploid yeast cells of two different mating types encounter each other, they fuse to form a diploid zygote (this constitutes a cross), which immediately undergoes meiosis to regenerate four individual haploid spores – a tetrad (the equivalent of an F1 generation). Since each meiotic te ...
A nested deletion approach to generate Cre deleter mice with
A nested deletion approach to generate Cre deleter mice with

... (HoxDC6; Gérard et al., 1996; Fig. 2C). We also introduced a transgene expressing the CRE enzyme under the control of the Sycp1 promoter, in order to express this enzyme at the time of chromosome pairing, during meiotic prophase (Vidal et al., 1998). In this way, around five percent of meiotic cells ...
1. Project summary
1. Project summary

... Skejby and belongs to the Aarhus University Institute of Clinical Medicine. RUMM performs its own research projects in collaborations with research groups in Denmark and abroad and also functions as a research service facility for clinical departments at Aarhus University Hospital. RUMM’s own resear ...
Uria_et_al_2006 _ADH paper
Uria_et_al_2006 _ADH paper

... chemical catalysis in many industrial applications (Van der Oost and De Graaff, 2001). In recent years, enzymes belonging to the oxidoreductase group such as alcohol dehydrogenases (ADHs) have caught much scientific attention in the pharmaceutical industries. They are highly desirable as biological ...
Synonymous Codon Usage, Accuracy of Translation, and Gene
Synonymous Codon Usage, Accuracy of Translation, and Gene

... crucial for protein function, whereas other positions are highly constrained. The nature and proportion of constrained amino acids vary widely according to the proteins. In absence of biochemical or structural data, these amino acids can be predicted by comparative sequence analysis: conserved resid ...
Guidelines for interpretation of 16S rRNA gene sequence
Guidelines for interpretation of 16S rRNA gene sequence

... interpretation of their large sequence dataset. On the other hand, Janda and Abbott suggested that a minimum of .99 %, and ideally .99.5 %, sequence similarity be used for species identification in their recommended guidelines (Janda & Abbott, 2007). Although different studies have identified groups ...
Supplementary Material (doc 236K)
Supplementary Material (doc 236K)

... This overview is for constructing the most basic parameters and it is shown in three sections: Phenotype search, Location search, and Other parameters. The minimum requirement is to specify at least one trait (phenoTrait) or one of the three location specifications. Both a trait and a location can b ...
Isolation and characterization of a repeated sequence (RPS1) of
Isolation and characterization of a repeated sequence (RPS1) of

... were virtually identical; however, one or two chromosomes were variable in size (Asakura et al., 1991). In virtually all cases, the chromosome that varied in size was chromosome 2. This suggested that chromosome 2 is too variable to be useful for distinguishing between strains. A similar variable ch ...
Transcriptional Regulation by FOXP1, FOXP2, and
Transcriptional Regulation by FOXP1, FOXP2, and

... Previous studies have already demonstrated that FOXP1, FOXP2, and FOXP4 proteins homodimerize with themselves and heterodimerize with each other in transfected HEK293 cells (Li et al. 2004). We performed coimmunoprecipitation assays to confirm that FOXP1, FOXP2, and FOXP4 heterodimerize in the HEK29 ...
significance of milk protein genes polymorphism for bulgarian
significance of milk protein genes polymorphism for bulgarian

... Since the discovery of milk protein genes polymorphism, the development of this field has been targeted at: understanding the biological significance of genetic variants; in the practice, clarifying the association between genetic variants and milk traits; in applied fields, selection and breeding t ...
Robust Prediction of Expression Differences among Human
Robust Prediction of Expression Differences among Human

... since the degree of correlation of SNPs to expression is associated with their genomic features such as location (e.g., distance from the transcription start site) or function [9–16,18–20] (e.g., within transcription factor binding sites), several studies used genomic features of SNPs as a prior on ...
Fumarase Deficiency
Fumarase Deficiency

... What is Fumarase Deficiency? Deficiency of the enzyme fumarate hydratase (fumarase) Found in Kreb cycle ...
The vertebrate genome annotation (Vega) database
The vertebrate genome annotation (Vega) database

... which is, as far as possible, kept synchronized with that of the Ensembl website. This strategy of keeping closely synchronized with Ensembl has advantages such as facilitating maintenance of the website—new features developed for Ensembl can sometimes become available to Vega with little or no deve ...
Identifying Genes Required for Cell Division in the Early C. elegans
Identifying Genes Required for Cell Division in the Early C. elegans

... relative to most animal cells. These qualities allow us to document embryonic cell ...
Chromosomes-and-Inherited-Traits (PowerPoint)
Chromosomes-and-Inherited-Traits (PowerPoint)

... Your genomes has 3 billion base pairs (every cell) ...
Unit 3
Unit 3

... What is the father’s most probable genotype? A daughter is afflicted. Since this is sex linked and recessive We know that dad must be afflicted because the daughter received a recessive X from each of her parents. ...
Analyzing microRNA Data and Integrating microRNA with Gene
Analyzing microRNA Data and Integrating microRNA with Gene

... regulate many genes, the PutativeGenes list will be much longer than the input microRNA list. The PutativeGenes list might be used for Biological Interpretation. Another useful way to examine the data would be to right-click on the Gene Symbol column (last one on the right) and select Create List w ...
Advances in maize genomics: the emergence of positional cloning
Advances in maize genomics: the emergence of positional cloning

... Sequencing strategies that use gene enrichment have been used successfully to avoid this repetitive DNA [10,11] and now most maize genes have been sequenced to some extent, although not anchored on the genetic map. Two papers have increased our awareness of polymorphism, reporting findings that the ...
Test Info Sheet
Test Info Sheet

... from a combination of a developmental defect and progressive atrophy of the cerebellum.1-4 Due to the in utero onset and involvement of the pons, PCH can be distinguished from other disorders of abnormal cerebellar development that occur due to prenatal infections, vascular anomalies, degenerative d ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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