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Biology Midterm Review
Biology Midterm Review

... 49. The differences between two molecules include the type of sugar that forms a section of the molecules and the identity of one of the four nitrogenous bases that make up another section of the molecules. These two molecules are – 50. The human body contains many different types of cells, includin ...
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Chapter 3, Section 4 The DNA Connection
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... ____ 11. In DNA, phosphodiester bonds join A. two phosphate groups B. bases and sugars C. phosphate groups and sugars D. phosphate groups and bases E. two sugar molecules ____ 12.Transcription of the lacZ and lacY genes of the lac operon begins when A. lactose binds to the operator B. RNA polymeras ...
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Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
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