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DNA
DNA

... • Genetic traits are passed through the genes, from parents to offspring • Traits can be influenced by the environment – Ex: your hair may become lighter after being in the sun for long periods of time – Ex: you may have a gene for tallness, but due to malnourishment (not enough food), you might nev ...
DNA Replication
DNA Replication

... that are identical (except for rare mutations). The two identical daughter chromosomes move toward opposite end of the cell. When the cell divides the daughter chromosomes are partitioned one to each daughter cell. ...
Slide 1
Slide 1

... binding to the promoter – Activator proteins bind to DNA enhancers and interact with other transcription factors – Silencers are repressors that inhibit transcription ...
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NOTES: 12.2 – 12.3 – DNA Structure

... -Can have 1000x more DNA than prokaryotic cells -DNA is located in the form of a number of chromosomes -# of chromosomes varies widely from species to species DNA molecules are long…how does DNA fit in the nucleus? ● It forms ...
Transgenic Organisms
Transgenic Organisms

... 3. Offspring of the recipient bacterium will carry a new combination of genes 4. Genetic marker – a gene that produces a known protein that can be used to “mark” bacteria that have taken up foreign DNA ...
Lecture 10 Biol302 Spring 2011
Lecture 10 Biol302 Spring 2011

...  Maternal-effect genes contribute to the formation of healthy eggs; effects of mutations in these genes may not affect the phenotype of the female making the eggs but may be seen in the next generation.  A maternal-effect mutation causes a mutant phenotype in the offspring of a female with a mutan ...
RNA interference - Creighton University
RNA interference - Creighton University

... processed in part by Dicer but function to effect posttranscriptional gene silencing in a manner distinct from that of siRNAs • The importance of miRNAs in regulating cellular processes through effects on target gene expression is reflected in the fact that many miRNA genes are highly conserved amon ...
Leukaemia Section t(2;21)(p11;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(2;21)(p11;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology

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The Flyswatter Game

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Genetic engineering and biotechnology
Genetic engineering and biotechnology

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ncb0908-1015 191KB Jan 02 2015 10:30:53 AM
ncb0908-1015 191KB Jan 02 2015 10:30:53 AM

... let alone Chinese characters, is rather easily assimilated. Imagine a world in which each of us knew only a fraction of the alphabet. Interdisciplinary education and research can ensure communication of ideas and advances, and will be essential to tackle complex trait diseases. Nonetheless, it is ri ...
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Epigenetics-2015

... EED2 (ESC) binds H3K27me3 and enhances methylation activity of EZH2 [E(Z)] on a separate histone ...
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Study Guide for LS
Study Guide for LS

... - DNA is shaped like a double helix or a twisted ladder. - In a DNA strand, the rungs (the part you step on) of the “ladder” are made of nucleotide bases. - In a DNA strand, the sides of the “ladder” are made of alternating sugar and phosphate ...
Science 9 Unit A 3.0
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Please pass last week`s warm up to the aisle. HW # 63: Read and
Please pass last week`s warm up to the aisle. HW # 63: Read and

... Humans  have  23  pairs  of  chromosomes  in  total   Here  are  some    human  chromosomes  inside  a  cell,   which  have  been  made  to  fluoresce.   ...
Genetic engineering
Genetic engineering

... well as among different species. DNA sequences within most genes contain the information to direct the order of amino acids within polypeptides according to the genetic code. In the code, a three-base sequence specifies one particular amino acid among the 20 possible choices. One or more polypeptide ...
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3.5.5 Explain the relationship between one gene

... Some proteins may consist of a number of polypeptide chains and thus need multiple genes (e.g. hemoglobin consists of four polypeptide subunits encoded by two different genes) When a gene is mutated it may lead to the synthesis of a defective polypeptide, hence affecting protein function The 'One Ge ...
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What are mutations and how do they affect the production

... When the base sequence of DNA is __________________, the ______________________ sequence is also changed. Since amino acids chain together to create a specific ____________________, mutations could affect the operation of an ____________________, preventing it from properly catalyzing a reaction or ...
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Recombinant DNA Technology

... • DNA library = collection of clones from one DNA donor – Categorized by: vector, source of DNA – Genomic library = all of the sequences from the genome of a single organism – cDNA library= complementary DNA, made using mRNA as a template ...
CLS 311 Basic Microbiology Lect 9: Bacterial Genatics
CLS 311 Basic Microbiology Lect 9: Bacterial Genatics

... This damage if not repaired can lead to cell death and , in animals lead to cancer. ...
Topic 4: Genetics - wfs
Topic 4: Genetics - wfs

Ch 14- 17 Unit Test - Akron Central Schools
Ch 14- 17 Unit Test - Akron Central Schools

... • Which of the following statements is true about protein synthesis in prokaryotes? • A) Extensive RNA processing is required before prokaryotic transcripts can be translated. • B) Translation can begin while transcription is still in progress. • C) Prokaryotic cells have complicated mechanisms for ...
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SEMINAR CANCELED- Rescheduled to January 28, 2016

... responsive genes and transcription factor genes to infer signals and pathways that drive pathogen gene regulation during invasive Candida albicans infection of a mammalian host. Environmentally responsive gene expression shows that there are early and late phases of infection. The early phase includ ...
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Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
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