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Phevor Combines Multiple Biomedical Ontologies for
Phevor Combines Multiple Biomedical Ontologies for

... traversable via the ontologies’ relationships (edges). For example, annotating a gene with the term ‘‘deaminase activity’’ makes it possible to deduce that the same gene encodes a protein with ‘‘catalytic activity.’’ In recent years, many biomedical ontologies have been created for the management of ...
Opportunities in Bioinformatics for Computer - People
Opportunities in Bioinformatics for Computer - People

... • gene families; • chromosomes. • Identification of • sequences that code for gene products/proteins; • sequences that act as regulatory elements. November 16, 2001 ...
Overview of the genes of watermelon1
Overview of the genes of watermelon1

... independent of rind thickness. The interaction of rind toughness and thickness needs to be studied. A single recessive gene su (Chambliss et al. 1968) eliminates bitterness in fruit of C. lanatus, and is allelic to the dominant gene (Su) for bitter flavor in the fruit of the colocynth (Citrullus co ...
Natural infection of Run1-positive vines by naïve genotypes of
Natural infection of Run1-positive vines by naïve genotypes of

... mildew infection of the canes is visible as dead, dark brown tissue. ...
SEGMENTAL VARIATION
SEGMENTAL VARIATION

... • Illumina HiSeq, the current industry leader in highthroughput sequencing, generates short reads from fragments 200 to 600 bp long. • Reading both ends of the same fragment gives you sequences that should lie 200 to 600 bp apart ...
Mixed questions
Mixed questions

... 3. Feedback inhibition is a reversible and dynamic process. Explain. 4. Compare and contrast repressible and inducible operons. 5. Site 3 examples of global control. Include the system name, environmental signal, the regulatory molecule and its activity and the number of genes regulated. 6. What is ...
Functional gene groups are concentrated within chromosomes
Functional gene groups are concentrated within chromosomes

... In the previous section, we checked whether genes from the same functional group tend to concentrate on fewer chromosomes than expected by chance. In this section, we would like to check whether genes from the same group that belong to the same chromosome tend to be closer than expected. In order to ...
zChap12_140901 - Online Open Genetics
zChap12_140901 - Online Open Genetics

... genes in other eukaryotes. It relies on two parts: a “driver” and a “responder” (Figure 12.10). The driver part is a gene encoding a yeast transcriptional activator protein called Gal4. It is separate from the responder part, which contains the enhancer sequence, or upstream activation sequence (UAS ...
Successive Losses of Central Immune Genes
Successive Losses of Central Immune Genes

... anoxia event approximately 95 Ma (Wilson and Norris 2001, Sinninghe Damsté et al. 2010). Additionally, these two anoxia events co-occurred with the continued opening northward of the Central Atlantic Ocean expanding the North Atlantic Ocean and the formation of a gateway between the South Atlantic ...
NOTE Phylogenetic analysis of Gram
NOTE Phylogenetic analysis of Gram

... distances on the tree, is shown. The tree showed that the Gram-positive bacteria form three groupings, i.e. ...
Cowden Syndrome
Cowden Syndrome

... People with a PTEN gene mutation are at risk for the non-cancerous growths discussed above. Women with Cowden syndrome have a 25 to 50 percent lifetime risk for developing breast cancer, with an average age of diagnosis between ages 38 and 46. Men with Cowden syndrome may have a slightly increased r ...
Genomic imprinting of a placental lactogen gene in Peromyscus
Genomic imprinting of a placental lactogen gene in Peromyscus

... stand out in all trees examined; a representative tree with relative support for each node is shown in Fig. 2c. First, pPl1 and pPl1-v group together very strongly. If these genes had direct orthologs in other species, this would not be expected; rather one of them would have another rodent Pl1-like ...
Super models
Super models

... information, and there is a wealth of Internet resources available to link DNA sequence information with the study of model organisms (Table 1). The number of predicted human genes is estimated to be between 26,000 and 40,000 (55, 95), although this number is controversial (23) and considered to be ...
Theoretical and Applied Genetics
Theoretical and Applied Genetics

... effective method to control this disease in canola production. In particular, blackleg resistance is considered as one of the most important traits in the canola breeding programs of all seed companies in Canada, Europe and Australia. Mapping blackleg resistance genes and eventually cloning these ge ...
2 Genetic Epidemiology - How to quantify, localize and identify
2 Genetic Epidemiology - How to quantify, localize and identify

... has evolved along with the advances in science. Commonly used definitions of a gene are: ‘a unit of inheritance’ or ‘a packet of genetic information that encodes a protein or RNA’. The estimated number of genes in the human genome is also a subject of debate. Not too long ago it was predicted that t ...
Lecture 13 - Mendel and the Gene Idea, Punnet Squares
Lecture 13 - Mendel and the Gene Idea, Punnet Squares

... • The most common lethal genetic disease in the United States, striking one out of every 2,500 people of European descent • The cystic fibrosis allele results in defective or absent chloride transport channels in plasma membranes leading to a buildup of chloride ions outside the cell • Symptoms incl ...
Decoding the Genome of an Alien
Decoding the Genome of an Alien

... genes are expressed in cells. In the octopus, nearly half of the genome was found to be composed of mobile elements called transposons, one of the highest proportions in the animal kingdom. Transposons replicate and move around with a life of their own, disrupting or enhancing gene expression and fa ...
Groups Basics - Bioinformatics Research Group at SRI International
Groups Basics - Bioinformatics Research Group at SRI International

... Click here to add a description. We can also change the names of the columns by clicking on them. Clicking on a column header changes the actions available for that column, such as the ability to make a new group, or choosing a transformation property. A group might have several columns, but the 1st ...
Supplementary Material
Supplementary Material

... remaining ambiguous words were 80.9%, 46.2%, 13.5% and 7.2% respectively for geneEnglish ambiguity, and 89.8%, 68.6%, 24.0% and 13.4% respectively for gene-UMLS ambiguity. Figure 2 shows the corresponding percentages of ambiguous words that were removed from the lists at different thresholds (10%, ...
PSet - CS109
PSet - CS109

... assuming that cell phone is in location Li (see the figure on the right). That calculation is based on knowledge of the dynamics of this particular cell tower and stochasticity of signal strength. As an example: the value of 0.05 in the highlighted cell on the left figure means that you believed the ...
Molecular evolution of the major chemosensory gene families in
Molecular evolution of the major chemosensory gene families in

... gene families to date. Putative functional and nonfunctional members of these families in the 12 genomes have been comprehensively identified by sequence similarity algorithms (Guo and Kim, 2007; Nozawa and Nei, 2007; Vieira et al., 2007; Gardiner et al., 2008). In some cases, the uncovered genome s ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... Learning ODE models from perturbation time series data • Batch 1 contains the most confident predictions: all predictions with probability of regulation pba > 0.99 according to the noise model learned from homozygous deletion data • Batch 2: all predictions with a score two standard deviations bel ...
Intro to Mendelian Genetics
Intro to Mendelian Genetics

... After 1000s of experiments, Mendel came up with some “rules of heredity”: 1.Rule of Unit Factors • EACH ORGANISM HAS 2 COPIES OF A GENE THAT CONTROLS EACH TRAIT; ONE COPY CAME FROM THE MALE PARENT AND ONE COPY CAME FROM THE FEMALE PARENT ...
Transcription – Gene regulation
Transcription – Gene regulation

... position that marks the known transcription start site (TSS) and search for conserved regions in the sequences. E.coli promoters are found to contain 3 conserved sequence features - a region approximately 6 bp long with consensus TATAAT at position -10 - a region approximately 6 bp long with consens ...
Managing Blackleg Resistance Breakdown and Trade Barriers through Blackleg
Managing Blackleg Resistance Breakdown and Trade Barriers through Blackleg

... •  The disease is emerging in farmers’ fields even on MR and Rrated cultivars – outbreaks are now more common! •  New races (strains) have been found since 2002 •  China has introduced restrictions on the import of canola seed •  Several growers practicing Tighter Rotations with canola •  Minimum or ...
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Gene desert

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