An Arabidopsis Mutant with a Reduced Leve1 of cabl40 RNA 1s a
... DMA Gel Blot Analysis of the let Mutant a crossover between the marker and let. Analysis of F3 lines showed close linkage of let to the brevipedicellus (bp) marker on chromosome 4. The F3 progeny from 55 individual F2 bp lines from W8 (bp, eceriferum-2 [cer2], apetala-2 [ap2]) x let demonstrated tha ...
... DMA Gel Blot Analysis of the let Mutant a crossover between the marker and let. Analysis of F3 lines showed close linkage of let to the brevipedicellus (bp) marker on chromosome 4. The F3 progeny from 55 individual F2 bp lines from W8 (bp, eceriferum-2 [cer2], apetala-2 [ap2]) x let demonstrated tha ...
Chromosomal rearrangements maintain a
... Michael A. Quail9, Helen Beasley9, Rebecca Glithero9, Christine Lloyd9, Sarah Sims9, Matthew C. Jones9, Jane Rogers9, Chris D. Jiggins7 & Richard H. ffrench-Constant4 ...
... Michael A. Quail9, Helen Beasley9, Rebecca Glithero9, Christine Lloyd9, Sarah Sims9, Matthew C. Jones9, Jane Rogers9, Chris D. Jiggins7 & Richard H. ffrench-Constant4 ...
The Schistosoma gene discovery program: state of the art
... great conservation of some genes in the various species, information obtained in one organism can be of relevance to the other. For both S. mansoni and S. japonicum, the Network decided not to adopt a reference strain as there is no evidence for gross chromosomal rearrangements among strains [16,17] ...
... great conservation of some genes in the various species, information obtained in one organism can be of relevance to the other. For both S. mansoni and S. japonicum, the Network decided not to adopt a reference strain as there is no evidence for gross chromosomal rearrangements among strains [16,17] ...
The Genome of Deep-Sea Vent Chemolithoautotroph
... chemolithoautotrophic sulfur-oxidizing bacteria isolated from deep-sea hydrothermal vents. This gammaproteobacterium has a single chromosome (2,427,734 base pairs), and its genome illustrates many of the adaptations that have enabled it to thrive at vents globally. It has 14 methyl-accepting chemota ...
... chemolithoautotrophic sulfur-oxidizing bacteria isolated from deep-sea hydrothermal vents. This gammaproteobacterium has a single chromosome (2,427,734 base pairs), and its genome illustrates many of the adaptations that have enabled it to thrive at vents globally. It has 14 methyl-accepting chemota ...
A Genetic, Deletion, Physical, and Human Homology Map of the
... mapped. Thus we identified wz8656 as a candidate for the deletion region because it is an ortholog of BTBD2, a gene that falls between CSNK1G2 and GPRK7 on the human map. It is also worth noting that homology segments (that is, regions of common gene order between zebrafish and human chromosomes) sh ...
... mapped. Thus we identified wz8656 as a candidate for the deletion region because it is an ortholog of BTBD2, a gene that falls between CSNK1G2 and GPRK7 on the human map. It is also worth noting that homology segments (that is, regions of common gene order between zebrafish and human chromosomes) sh ...
Draft of first homework
... It is unrealistic to think that there are no signals whatsoever on those chromosomes lacking one, especially since we have TWO experiments saying the same thing (also, when we looked at human ERA, it covered all human chromosomes) . We also have genes all over all the chromosomes. Either something w ...
... It is unrealistic to think that there are no signals whatsoever on those chromosomes lacking one, especially since we have TWO experiments saying the same thing (also, when we looked at human ERA, it covered all human chromosomes) . We also have genes all over all the chromosomes. Either something w ...
Tps1 regulates the pentose phosphate pathway, nitrogen
... mutant in vivo. We subcloned the 8 kb PstI fragment into the sulphonylurea-carrying vector pCB1532 (Carroll et al., 1994) to give pRAW8, and removed a 2 kb SmaI fragment to give pRAW9. To facilitate site directed mutagenesis, a 2.8 kb NotI and NdeI fragment was digested from pRAW9 and subcloned int ...
... mutant in vivo. We subcloned the 8 kb PstI fragment into the sulphonylurea-carrying vector pCB1532 (Carroll et al., 1994) to give pRAW8, and removed a 2 kb SmaI fragment to give pRAW9. To facilitate site directed mutagenesis, a 2.8 kb NotI and NdeI fragment was digested from pRAW9 and subcloned int ...
Fregene recombination model in detail
... Each subregion is also associated with a ’background’ rate (blue lines on figure 1), representing the base recombination rate for any site within the subregion (whether it belongs to a hotspot or not). Its computation involves the proportion of recombination occurring in hotspots, the user specifies ...
... Each subregion is also associated with a ’background’ rate (blue lines on figure 1), representing the base recombination rate for any site within the subregion (whether it belongs to a hotspot or not). Its computation involves the proportion of recombination occurring in hotspots, the user specifies ...
Deletion Upstream of the Human a Globin
... a 56-year-old man who initially complained of anorexia and weight loss for which no cause was found. The presenting symptoms eventually resolved without treatment. A routine blood count showed a hypochromic microcytic anemia in the absence of iron deficiency. H b electrophoresis showed normal propor ...
... a 56-year-old man who initially complained of anorexia and weight loss for which no cause was found. The presenting symptoms eventually resolved without treatment. A routine blood count showed a hypochromic microcytic anemia in the absence of iron deficiency. H b electrophoresis showed normal propor ...
molecularevolution.rnaseq
... Statistical segmentation of chromatin modifications uses continuity of segments to increase power for interval detection ...
... Statistical segmentation of chromatin modifications uses continuity of segments to increase power for interval detection ...
A Molecular Profile of the Malignant Transformation of Plasma Cells
... microarrays interrogating ~6,800 genes. On hierarchical clustering analysis, normal and MM PCs were differentiated and 4 distinct subgroups of MM (MM1, MM2, MM3 and MM4) identified. The expression patterns of MM1 was similar to normal PCs and MGUS whereas MM4 was similar to MM cell lines. Clinical p ...
... microarrays interrogating ~6,800 genes. On hierarchical clustering analysis, normal and MM PCs were differentiated and 4 distinct subgroups of MM (MM1, MM2, MM3 and MM4) identified. The expression patterns of MM1 was similar to normal PCs and MGUS whereas MM4 was similar to MM cell lines. Clinical p ...
Kinetic MoDiversity of Hydrocarbon-Related Catabolic Genes in Oil
... Page 2 of 7 catalytic domain containing mononuclear iron [23]. The dioxygenases belong to a large family known as aromatic-ring-hydroxylating dioxygenases (ARHDs) [24]. These genes are located in chromosomal or plasmid DNA and were identified in bacterial strains belonging to α-Proteobacteria (Sphin ...
... Page 2 of 7 catalytic domain containing mononuclear iron [23]. The dioxygenases belong to a large family known as aromatic-ring-hydroxylating dioxygenases (ARHDs) [24]. These genes are located in chromosomal or plasmid DNA and were identified in bacterial strains belonging to α-Proteobacteria (Sphin ...
Using gene networks to drug target identification
... inhibition or activation on multiple signaling pathways. Graphical models are often used to describe genetic networks. Generally, a gene network could be presented in a directed graph, in which nodes indicate genes and edges represent regulations between genes (e.g. activation or suppression). Analy ...
... inhibition or activation on multiple signaling pathways. Graphical models are often used to describe genetic networks. Generally, a gene network could be presented in a directed graph, in which nodes indicate genes and edges represent regulations between genes (e.g. activation or suppression). Analy ...
the Acetyl-Coenzyme A
... ascomycete homologs, there are no introns in the coding sequence. The first ATG codon of the open reading frame is in an unusual context for a translational start site, while the next ATG. 24 codons downstream. is in a more conventional context. Possible implications of two alternative translational ...
... ascomycete homologs, there are no introns in the coding sequence. The first ATG codon of the open reading frame is in an unusual context for a translational start site, while the next ATG. 24 codons downstream. is in a more conventional context. Possible implications of two alternative translational ...
Molecular Evolution of Nitrate Reductase Genes
... 1992). The heme domains have 32–48% amino acid homology with the superfamily of cytochrome b5 proteins such as cytochrome b2, b5, flavocytochrome b2, and sulfite oxidase. The FAD domains share 47% identity with the FAD domain of cytochrome b5. NR genetics, biochemistry, and molecular biology have be ...
... 1992). The heme domains have 32–48% amino acid homology with the superfamily of cytochrome b5 proteins such as cytochrome b2, b5, flavocytochrome b2, and sulfite oxidase. The FAD domains share 47% identity with the FAD domain of cytochrome b5. NR genetics, biochemistry, and molecular biology have be ...
The promoter of the Arabidopsis nuclear gene COX5b
... anthers and pollen and the central leaf vein. Quantitative measurements in extracts prepared from different organs suggested that expression is higher in roots. The analysis of progressive upstream deletions of the promoter suggested the presence of negative regulatory elements, preferentially activ ...
... anthers and pollen and the central leaf vein. Quantitative measurements in extracts prepared from different organs suggested that expression is higher in roots. The analysis of progressive upstream deletions of the promoter suggested the presence of negative regulatory elements, preferentially activ ...
Touring Ensembl: A practical guide to genome browsing Open Access
... at the 5' end of the IL2 transcript and flanking sequence [12-14]. Within only 200 bp upstream of the translational start site, binding sites for proteins such as NF-κB, AP-1, and NFAT (nuclear factor of activated T-cells), DNase I hypersensitive sites and a TATA box can all be found. These regions ...
... at the 5' end of the IL2 transcript and flanking sequence [12-14]. Within only 200 bp upstream of the translational start site, binding sites for proteins such as NF-κB, AP-1, and NFAT (nuclear factor of activated T-cells), DNase I hypersensitive sites and a TATA box can all be found. These regions ...
MGI-Guidelines for Nomenclature of Genes, Genetic Markers
... homolog of an already named gene in another species can be named as "-like" "-homolog" or "related." (Note: this is not the same as "related sequence" which applies to related sequences within mouse or within rat.) The gene name or symbol should not include the name mouse or the abbreviation "M" for ...
... homolog of an already named gene in another species can be named as "-like" "-homolog" or "related." (Note: this is not the same as "related sequence" which applies to related sequences within mouse or within rat.) The gene name or symbol should not include the name mouse or the abbreviation "M" for ...
1. dia
... and women in the genetic background. Those genes and pathways associated with obesity are potential targets for tailoring therapy for a ...
... and women in the genetic background. Those genes and pathways associated with obesity are potential targets for tailoring therapy for a ...
Case Report Section
... and metaphase cells revealing that the break-apart 5'MLL segment is translocated to the derivative X chromosome. The patient achieved a complete hematological remission with chemotherapy one month later. Chromosomal and FISH studies performed in April, June, August and December confirmed the complet ...
... and metaphase cells revealing that the break-apart 5'MLL segment is translocated to the derivative X chromosome. The patient achieved a complete hematological remission with chemotherapy one month later. Chromosomal and FISH studies performed in April, June, August and December confirmed the complet ...
Conditions for gene disruption by homologous
... Materials and methods and electroporated with 300 ng of pSVA78 plasmid DNA (Table 2). This plasmid harbors the lacS gene with flanking regions of the Sso02684 and Sso2681 genes (upstream flanking region was 733 bp, downstream flanking region was 756 bp). Upon transformation of the cells, the deletio ...
... Materials and methods and electroporated with 300 ng of pSVA78 plasmid DNA (Table 2). This plasmid harbors the lacS gene with flanking regions of the Sso02684 and Sso2681 genes (upstream flanking region was 733 bp, downstream flanking region was 756 bp). Upon transformation of the cells, the deletio ...
A statistical framework for genome
... with phenotypic class distinction. Larger values mean more significant correlation. For all data analyses in this paper, we used genotype-based single-locus association test because it can better capture the interaction between alleles at a single locus. Simulations also indicated that results from ...
... with phenotypic class distinction. Larger values mean more significant correlation. For all data analyses in this paper, we used genotype-based single-locus association test because it can better capture the interaction between alleles at a single locus. Simulations also indicated that results from ...
Introduction: - Statistical Science
... syndrome (DS, n=14) and control individuals (n=25) [Aravind add ref]. When we probe the dataset with GSEA and the un-weighted p=0 statistic using the set of all the 243 genes on chr21, we find a small enrichment signal. For p=1 the enrichment statistic is much higher but the set is still not signifi ...
... syndrome (DS, n=14) and control individuals (n=25) [Aravind add ref]. When we probe the dataset with GSEA and the un-weighted p=0 statistic using the set of all the 243 genes on chr21, we find a small enrichment signal. For p=1 the enrichment statistic is much higher but the set is still not signifi ...
GENE MUTATIONS - The Open Door Web Site : Home Page
... Pro-Glu-Glu-Cys-Gly Amino acids © 2010 Paul Billiet ODWS ...
... Pro-Glu-Glu-Cys-Gly Amino acids © 2010 Paul Billiet ODWS ...