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Functional analyses of genetic pathways controlling
Functional analyses of genetic pathways controlling

... MADS-box genes are crucial regulators of floral development, yet how their functions have evolved to control different aspects of floral patterning is unclear. To understand the extent to which MADS-box gene functions are conserved or have diversified in different angiosperm lineages, we have exploi ...
document
document

... The basic idea is similar to finding suppressors. 1. the process in question involves the combined action of many proteins. 2. the successful execution of the process requires sufficient levels of all the components. 3. If levels of two components are lowered simultaneously, that can result in stron ...
Candidate gene analysis in a case of congenital absence of the
Candidate gene analysis in a case of congenital absence of the

... HOXA13 in the ectocervix and upper vagina [16]. Abnormalities in the development of mullerian structures were observed in mice with Hox gene mutations [17]. Hoxa11 mutant female mice display normal uteri at birth, but decreased cellular proliferation/increased apoptosis result in the absence of stro ...
Document
Document

... What is the advantage of these cells over other neurons or organs in terms of transplants? These transplanted cells will not be rejected (destroyed by the immune system) because they are genetically identical to the patient (your antibodies will not bind to them). ...
Document
Document

... A child who inherits the genes bb will have blue eyes In the F2 generation the ratio of brown eyed children to blue eyes will be 3 to 1 ...
Plant Molecular Biology
Plant Molecular Biology

... To isolate hybrids resulting from in vivo homologous recombination, 5/~g of plasmid pMP600 or pMP800 DNA was treated with 80 units of Eco RI for 3 hours and subsequently transformed to E. coli KMBLl164. The insertion of the CAT gene in the used plasmids is an improvement of the method described by T ...
Accounting for Non-Genetic Factors Improves the Power of eQTL
Accounting for Non-Genetic Factors Improves the Power of eQTL

... We applied both the standard eQTL method and the FA-eQTL method to the HapMap Phase II genotype data (4) and corresponding gene expression measurements (12). Both methods were applied to chromosomes 2, 7, 11 and X. For each chromosome, only probes for genes within that chromosome were included, so t ...
Proprietary Databases
Proprietary Databases

... The Personalis Regulatory Regions Database contains several hundred thousand putative transcription factor binding sites/regulatory regions. These regulatory annotations enable us to interpret intergenic and other non-coding variants that may have a significant impact on gene expression and function ...
Gene mapping - Australian Mathematical Sciences Institute
Gene mapping - Australian Mathematical Sciences Institute

... - The first generation of these plants, first-generation (F1) hybrids, were all yellow - These first-generation hybrids were then permitted to self cross. Some of the second generation (F2) were green and some yellow. In fact he found 75 % were yellow and 25 % green. ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... In this example of gene kissing, copies of the Drosophila melanogaster Fab7 regulatory element that are present on two different chromosomes co-localize in the cell nucleus. DAPI (4′,6-diamidino-2-phenylindole) is the DNA counterstain, sd shows the position of a transgenic Fab7 copy that is inserted ...
Divining Biological Pathway Knowledge from High
Divining Biological Pathway Knowledge from High

... The KEGG Node Table now has two extra columns in yellow. ‘Visible Neighbors’ shows the number of genes in each KEGG pathway that are also visible in the Network View. ‘Visible Enrichment’ shows the over-representation statistic for each KEGG pathway calculated using the hypergeometric distribution ...
A GO annotation is
A GO annotation is

... chromosome Not all chromosomes have replication forks ...
Conservation and Coevolution in the Scale
Conservation and Coevolution in the Scale

... Fraser, Wall, and Hirsh 2003). A recent study that dealt with several such relationships simultaneously demonstrated correlations between different measures of evolutionary conservation and various functional genomic parameters (Krylov et al. 2003). However, the findings of some of these evolutionar ...
Gene Section IGH@ (Immunoglobulin Heavy) Atlas of Genetics and Cytogenetics
Gene Section IGH@ (Immunoglobulin Heavy) Atlas of Genetics and Cytogenetics

... IGHC genes. Eighty-two to 88 IGHV genes belong to 7 subgroups, whereas 41 pseudogenes, which are too divergent to be assigned to subgroups, have been assigned to 4 clans. Seven non-mapped IGHV genes have been described as insertion/deletion polymorphism but have not yet been precisely located. The m ...
View - Max-Planck
View - Max-Planck

... the 1784-bp BamHI cDNA fragment. In situ hybridization and histology of whole embryos was performed as described, except that specimens from all stages were treated with proteinase K (Pera and Kessel 1997; Stein and Kessel 1995; Lemaire et al. 1997). The first, low transcript levels were detected in ...
Construction of consecutive deletions of the Escherichia
Construction of consecutive deletions of the Escherichia

... cells include telomeric sequences, which are necessary for chromosome maintenance and centromeric regions, which are required for stable segregation of eukaryotic chromosomes. The centromere is a unique region in each chromosome: in theory, two centromeres on one chromosome can pull apart the chromo ...
Identification of Mga1, a G‐protein α‐subunit gene involved in
Identification of Mga1, a G‐protein α‐subunit gene involved in

... sterility and enhanced deoxynivalenol and zearalenone production (Hicks et al., 1997; Yu et al., 2008). While substantial basic knowledge regarding the functional role of G-proteins has been gained from other fungi, especially model filamentous fungi and pathogenic fungi, our understanding of the bi ...
Integrons and the Origin of Antibiotic Resistance Gene Cassettes
Integrons and the Origin of Antibiotic Resistance Gene Cassettes

... repeats), led to discovery of another type of integron, a superintegron (SI) (Fig. 2). This distinct type of integron is now known to be an integral component of many g-proteobacterial genomes. The integron discovered in chromosome 2 of V. cholerae possesses a specific integrase, IntIA, that is rela ...
Gene clusters for β-lactam antibiotics and control of their expression
Gene clusters for β-lactam antibiotics and control of their expression

... enzymes that carry out these two sequential steps. Genes cefE and cefF encode proteins with about 70% identity in amino acids, and which are 60% identical to the protein encoded by cefEF in fungi. It is likely that a gene duplication event served as the origin of the two genes, which subsequently be ...
Genet Mol Res, 13 - Funpec-RP
Genet Mol Res, 13 - Funpec-RP

... Several population-based epidemiological studies in Japan have reported a prevalence of OPLL ranging from 1.5 to 2.4% (Okamoto and Yasuma, 1967; Izawa, 1980; Matsunaga and Sakou, 2011), although most of these studies were conducted over 30 years ago and were based on low-quality plain films. A Japan ...
Genome Analysis Excerpt from Chapter 11
Genome Analysis Excerpt from Chapter 11

... these rearrangements between species to discover how many there were, in what order they occurred, and how random they were is a challenging computational problem. One of the most interesting areas of genome analysis is comparing genomes of similar organisms, especially the primates that are the clo ...
23717
23717

... The crosses were set up in duplicates, so there were two bottles of the 1A cross and two bottles of the 1B cross. In order to make these crosses, flies from both the amanita culture bottles and the wild-type culture bottles were etherized and sexed. Thirty virgin amanita females and thirty amanita m ...
Full text in pdf - International Microbiology
Full text in pdf - International Microbiology

... enzymes that carry out these two sequential steps. Genes cefE and cefF encode proteins with about 70% identity in amino acids, and which are 60% identical to the protein encoded by cefEF in fungi. It is likely that a gene duplication event served as the origin of the two genes, which subsequently be ...
Extensions to Mendel`s Law
Extensions to Mendel`s Law

Life: The Science of Biology, 10e
Life: The Science of Biology, 10e

... Neurons respond to electrical stimulation by generating an action potential. The electrical activity of a stimulated transformed fibroblast cell is shown in Fig. A: 8, 12, and 20 days after addition of the transcription factors. What is the magnitude of the action potential of the transformed cell i ...
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