MEF2 activity during embryogenesis - Development
... for the MEF2 family in neuronal differentiation. The cell type distribution of MEF2 activity has been controversial. Some studies have reported that MEF2 DNAbinding activity is restricted to muscle cells (Gossett et al., 1989; Cserjesi et al., 1991; Yu et al., 1992; Breitbart et al., 1993), whereas ...
... for the MEF2 family in neuronal differentiation. The cell type distribution of MEF2 activity has been controversial. Some studies have reported that MEF2 DNAbinding activity is restricted to muscle cells (Gossett et al., 1989; Cserjesi et al., 1991; Yu et al., 1992; Breitbart et al., 1993), whereas ...
De novo mutations in familial adenomatous polyposis (FAP)
... parental origin of different genetic disorders is complex and the present results resembles those found in von Hippel-Lindau disease.14 The failure to observe an underlying paternal bias among FAP patients could be explained by a selective disadvantage of the mutated male germ cell or by maternal im ...
... parental origin of different genetic disorders is complex and the present results resembles those found in von Hippel-Lindau disease.14 The failure to observe an underlying paternal bias among FAP patients could be explained by a selective disadvantage of the mutated male germ cell or by maternal im ...
DYAD in meiotic chromosome organisation - Development
... region of genomic DNA which was then digested with a panel of restriction enzymes, and electrophoresed on a gel to identify polymorphisms between the Ler and No-O ecotypes and in some cases between Ler and Col-O. Recombinants north and south of dyad were first screened and identified with respect to ...
... region of genomic DNA which was then digested with a panel of restriction enzymes, and electrophoresed on a gel to identify polymorphisms between the Ler and No-O ecotypes and in some cases between Ler and Col-O. Recombinants north and south of dyad were first screened and identified with respect to ...
Suppressors of Yeast Actin Mutations.
... DNA was extracted from cultures of colonies that grew on these plates by the method of HOLMet al. (1986) and the complementing plasmids recovered in E. coli strain HBlO 1 by selecting for the plasmid's ampicillin-resistancegene. The restriction maps of the complementing plasmids (pRB390 and pRB391 a ...
... DNA was extracted from cultures of colonies that grew on these plates by the method of HOLMet al. (1986) and the complementing plasmids recovered in E. coli strain HBlO 1 by selecting for the plasmid's ampicillin-resistancegene. The restriction maps of the complementing plasmids (pRB390 and pRB391 a ...
Evolution of the enzymes of the citric acid cycle and the
... to other thiamine-dependent enzymes that perform biochemically similar reactions: transketolase, which catalyzes the transfer of two-carbon units in the Calvin cycle and oxidative pentose phosphate pathway, 1-deoxyxylulose5-phosphate synthase, which transfers a C2 unit from pyruvate to D-glyceraldeh ...
... to other thiamine-dependent enzymes that perform biochemically similar reactions: transketolase, which catalyzes the transfer of two-carbon units in the Calvin cycle and oxidative pentose phosphate pathway, 1-deoxyxylulose5-phosphate synthase, which transfers a C2 unit from pyruvate to D-glyceraldeh ...
The B-cell maturation factor Blimp-1 specifies vertebrate slow
... contrasts with ubotp39 mutants, in which we detected variable expression of slow MyHC (Fig. 3a–c). Despite this arrest, the adaxial cells retained their ability to transduce Hh and to commit to the myogenic fate, as indicated by the normal expression patterns of ptc1 and myoD (Fig. 3d,e and data not ...
... contrasts with ubotp39 mutants, in which we detected variable expression of slow MyHC (Fig. 3a–c). Despite this arrest, the adaxial cells retained their ability to transduce Hh and to commit to the myogenic fate, as indicated by the normal expression patterns of ptc1 and myoD (Fig. 3d,e and data not ...
The Normal Uniform Differential Gene Expression
... compared to the plot of the normalized log ratios, lRnorm, produced by the normalization method versus the log intensities, lI, (along with the loess fitted mean lines of both). > #lRnorm is the mean and variance normalized log ratios for the genes ...
... compared to the plot of the normalized log ratios, lRnorm, produced by the normalization method versus the log intensities, lI, (along with the loess fitted mean lines of both). > #lRnorm is the mean and variance normalized log ratios for the genes ...
Role of 1-aminocyclopropane-1-carboxylate (ACC) Synthases
... in flower petal senescence is important and is cultivar dependent with variable cultivar sensitivity. 2) They point to the need for additional work, because results in some instances are contradictory. While it makes sense in the studies with the miniature potted roses of short- and long-lived flowe ...
... in flower petal senescence is important and is cultivar dependent with variable cultivar sensitivity. 2) They point to the need for additional work, because results in some instances are contradictory. While it makes sense in the studies with the miniature potted roses of short- and long-lived flowe ...
Classical Genetics - Morinville Community High School
... and body proportion may also be genetically determined (although such characters as body size may be profoundly influenced by environment). The tremendous number of genetic traits makes humans extremely variable. With the exception of identical twins, it is highly improbable that any two persons wil ...
... and body proportion may also be genetically determined (although such characters as body size may be profoundly influenced by environment). The tremendous number of genetic traits makes humans extremely variable. With the exception of identical twins, it is highly improbable that any two persons wil ...
Prostate cancer - American Cancer Society
... Screening is testing to find cancer, or other disease, in people who have no symptoms. Screening can help find cancers in an early stage when they are small, have not spread, and are more easily cured. Screening for prostate cancer can be done with: Prostate-Specific Antigen (PSA) blood test ...
... Screening is testing to find cancer, or other disease, in people who have no symptoms. Screening can help find cancers in an early stage when they are small, have not spread, and are more easily cured. Screening for prostate cancer can be done with: Prostate-Specific Antigen (PSA) blood test ...
University of Groningen Stress responses and sugar metabolism in
... In addition to these phosphoproteins also low molecular weight molecules such as NADP, glucose‐6‐phosphate (G6P) and fructose‐1,6‐bisphosphate (FBP) can modulate either DNA‐ binding properties or the interaction with the transcriptional machinery of the CcpA‐(HPr‐ Ser ...
... In addition to these phosphoproteins also low molecular weight molecules such as NADP, glucose‐6‐phosphate (G6P) and fructose‐1,6‐bisphosphate (FBP) can modulate either DNA‐ binding properties or the interaction with the transcriptional machinery of the CcpA‐(HPr‐ Ser ...
Control of GL2 expression in Arabidopsis leaves and trichomes
... putative shoot transcription domains ...
... putative shoot transcription domains ...
Alfred Henry Sturtevant - National Academy of Sciences
... age map. He and others had noticed, however, that excessive variation in the amount of crossing-over sometimes occurs. The factors responsible were isolated by Sturtevant and by Muller around 1915 and were shown to act as dominant cross-over suppressors. The first clue to the nature of these factors ...
... age map. He and others had noticed, however, that excessive variation in the amount of crossing-over sometimes occurs. The factors responsible were isolated by Sturtevant and by Muller around 1915 and were shown to act as dominant cross-over suppressors. The first clue to the nature of these factors ...
Genetic Interaction of BBS1 Mutations with
... families, mutations in BBS1 can interact genetically with mutations at each of the other known BBS genes, as well as at unknown loci, to cause the phenotype. Consistent with this model, we identified homozygous M390R alleles, the most frequent BBS1 mutation, in asymptomatic individuals in two famili ...
... families, mutations in BBS1 can interact genetically with mutations at each of the other known BBS genes, as well as at unknown loci, to cause the phenotype. Consistent with this model, we identified homozygous M390R alleles, the most frequent BBS1 mutation, in asymptomatic individuals in two famili ...
IDO-Staph-Goldfain
... referred to as the integration site sequence for SCC (ISS), which serves as a target for ccr-mediated recombination, and • (4) the presence of flanking direct repeat sequences containing the ...
... referred to as the integration site sequence for SCC (ISS), which serves as a target for ccr-mediated recombination, and • (4) the presence of flanking direct repeat sequences containing the ...
the kinship theory of genomic imprinting - Fischer Lab
... gene expression X. Then the kinship theory predicts that the evolutionarily stable strategy (ESS) at the locus will be either ‘symmetric’ or ‘asymmetric’ (21). A symmetric ESS occurs when maternally derived and paternally derived alleles favor the same total level of gene expression. At such an ESS, ...
... gene expression X. Then the kinship theory predicts that the evolutionarily stable strategy (ESS) at the locus will be either ‘symmetric’ or ‘asymmetric’ (21). A symmetric ESS occurs when maternally derived and paternally derived alleles favor the same total level of gene expression. At such an ESS, ...
Telomere Shortening and Tumor Formation by Mouse Cells Lacking
... Goal 3: Detection of telomerase activity in mTR-/- mice and mouse embryonic fibroblasts (MEF) MEF cultures and S100 extracts from brain, liver, thymus and spleen were tested for telomerase activity with the ...
... Goal 3: Detection of telomerase activity in mTR-/- mice and mouse embryonic fibroblasts (MEF) MEF cultures and S100 extracts from brain, liver, thymus and spleen were tested for telomerase activity with the ...
Two distinct tumor suppressor loci within chromosome 11p15
... component (P = 0.016). DCIS of the breast is considered a pre-invasive stage of breast cancer and may be a precursor of infiltrating breast cancer (26). Although the number of tumors analyzed is small, the statistically significant association between LOH in region 1 and such tumors suggests the inv ...
... component (P = 0.016). DCIS of the breast is considered a pre-invasive stage of breast cancer and may be a precursor of infiltrating breast cancer (26). Although the number of tumors analyzed is small, the statistically significant association between LOH in region 1 and such tumors suggests the inv ...
- BioMed Central
... in the generation of a massive amount of expression data. One of the greatest challenge we are faced with is to then analyse the data as a whole and extract the meaningful relationships among specific genes. Standard methods such as SAM [6] or machine learning algorithms [7] are able to detect patte ...
... in the generation of a massive amount of expression data. One of the greatest challenge we are faced with is to then analyse the data as a whole and extract the meaningful relationships among specific genes. Standard methods such as SAM [6] or machine learning algorithms [7] are able to detect patte ...
Drosophila rhino Encodes a Female-Specific Chromo
... and Laski 1994; Heino et al. 1995; Reed and OrrWeaver 1997). For example, mutations in sop arrest oogenesis at S5, when pairing has begun to break down but five distinct chromosome arms are still visible in the nurse cells. Prior to degeneration, several consecutive S5 egg chambers are present withi ...
... and Laski 1994; Heino et al. 1995; Reed and OrrWeaver 1997). For example, mutations in sop arrest oogenesis at S5, when pairing has begun to break down but five distinct chromosome arms are still visible in the nurse cells. Prior to degeneration, several consecutive S5 egg chambers are present withi ...
Elyse Coolidge
... abusers, and 94% of heroin addicts are reported to have contracted Hepatitis C (Comings et al., 1999). As a result, heroin, its metabolite morphine, the opioid system, and the cannabinoid system, which has a demonstrated relationship to opioid addiction, have been studied extensively in the past 20 ...
... abusers, and 94% of heroin addicts are reported to have contracted Hepatitis C (Comings et al., 1999). As a result, heroin, its metabolite morphine, the opioid system, and the cannabinoid system, which has a demonstrated relationship to opioid addiction, have been studied extensively in the past 20 ...
Genomics of adaptation and speciation in cichlid fishes: recent
... species, failed to identify relevant polymorphisms. Combined, this suggests that mutations in Mc1r or surrounding regions have no effect on the gold Midas phenotype and the causal genetic locus remains to be found. In contrast, coloration is sex-linked in many African cichlids and may be associated ...
... species, failed to identify relevant polymorphisms. Combined, this suggests that mutations in Mc1r or surrounding regions have no effect on the gold Midas phenotype and the causal genetic locus remains to be found. In contrast, coloration is sex-linked in many African cichlids and may be associated ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.