
Transcription and Translation
... Remember: MR CATAP (mRNA, ribosome, codon, anticodon, tRNA, amino acid, polypeptide) • mRNA binds to a ribosome which initiates translation • The mRNA is read in codons (from start codon = AUG) • Anticodons on tRNA align opposite appropriate codons ...
... Remember: MR CATAP (mRNA, ribosome, codon, anticodon, tRNA, amino acid, polypeptide) • mRNA binds to a ribosome which initiates translation • The mRNA is read in codons (from start codon = AUG) • Anticodons on tRNA align opposite appropriate codons ...
doc - FSU Biology
... all bacterial ribosomes, and the 50 or more different transfer RNA (tRNA) genes that are transcribed into the tRNAs that function as the adapter molecules in protein synthesis. One other RNA gene commonly found is the M1 RNA gene, which codes for the enzymatic portion of Ribonuclease P, the prototyp ...
... all bacterial ribosomes, and the 50 or more different transfer RNA (tRNA) genes that are transcribed into the tRNAs that function as the adapter molecules in protein synthesis. One other RNA gene commonly found is the M1 RNA gene, which codes for the enzymatic portion of Ribonuclease P, the prototyp ...
Cell 103 Heredity and Society
... non-hereditary diseases. Students will be familiar with tools used to manipulate genes. Course learning outcomes: After completion of this course, successful students will be able to: - Describe genes and relate them to protein synthesis leading to genetic traits - Explain the rules governing gene t ...
... non-hereditary diseases. Students will be familiar with tools used to manipulate genes. Course learning outcomes: After completion of this course, successful students will be able to: - Describe genes and relate them to protein synthesis leading to genetic traits - Explain the rules governing gene t ...
Gene Section FAM57A (family with sequence similarity 57, member A)
... CT120A protein was a potential molecular target for treatment of lung cancers. CT120A was overexpressed in 15 cases of the 16 primary lung cancer specimens. Knockdown of CT120A by small hairpin RNA in the human lung adenocarcinoma cell line SPC-A-1 cells resulted in a reduced cell growth rate in vit ...
... CT120A protein was a potential molecular target for treatment of lung cancers. CT120A was overexpressed in 15 cases of the 16 primary lung cancer specimens. Knockdown of CT120A by small hairpin RNA in the human lung adenocarcinoma cell line SPC-A-1 cells resulted in a reduced cell growth rate in vit ...
Microarray Data Analysis
... • Fold change is often much greater for low intensity samples (absolute amount of RNA is small) • If you normalize by dividing all samples by the mean, then genes that express at this level will have their variation suppressed ...
... • Fold change is often much greater for low intensity samples (absolute amount of RNA is small) • If you normalize by dividing all samples by the mean, then genes that express at this level will have their variation suppressed ...
Virus - World Health Organization
... A virus is an obligate parasite dependent on nutrients inside cells for its metabolic and reproductive needs. It consist of a strand of either DNA or RNA, but not both, separated by a protein covering called a capsid (Symons etal. 2000). Viruses consist of two or three parts : all viruses have genes ...
... A virus is an obligate parasite dependent on nutrients inside cells for its metabolic and reproductive needs. It consist of a strand of either DNA or RNA, but not both, separated by a protein covering called a capsid (Symons etal. 2000). Viruses consist of two or three parts : all viruses have genes ...
The Master Molecule
... percent of human DNA encodes information. The remaining 97% is called junk DNA, the function of which is not yet known. Specific genes, called exons, are activated by promoter genes located along the sequence of the DNA molecule. Noncoding sequences are called introns, and do not lead to the producti ...
... percent of human DNA encodes information. The remaining 97% is called junk DNA, the function of which is not yet known. Specific genes, called exons, are activated by promoter genes located along the sequence of the DNA molecule. Noncoding sequences are called introns, and do not lead to the producti ...
Review of relevant topics prior to “Linkage” lectures
... DNA as it exists in the cell- normally vs. metaphase; w/ respect to chromosomes ...
... DNA as it exists in the cell- normally vs. metaphase; w/ respect to chromosomes ...
Epigenetics: We often discuss genes as if their presence in our cells
... Epigenetics: We often discuss genes as if their presence in our cells assures that they will be expressed. This is not true. The expression of genes is highly regulated. That is to say that our genes can be turned on or off, and this can be good (most of the time) or bad (sometimes). We understand t ...
... Epigenetics: We often discuss genes as if their presence in our cells assures that they will be expressed. This is not true. The expression of genes is highly regulated. That is to say that our genes can be turned on or off, and this can be good (most of the time) or bad (sometimes). We understand t ...
ALE #7
... packed by wrapping itself around histone protein and coiling into tight helical fibers and supercoils. In this highly packaged state, transcription is nearly impossible. RNA polymerase will be blocked from binding to promoters b. X chromosome inactivation – early in embryonic development of female m ...
... packed by wrapping itself around histone protein and coiling into tight helical fibers and supercoils. In this highly packaged state, transcription is nearly impossible. RNA polymerase will be blocked from binding to promoters b. X chromosome inactivation – early in embryonic development of female m ...
Macro-Microarray
... few transcripts per 10 cells to several thousand transcripts in a single cell. In addition, they look at so many genes that they can actually be used to distinguish between specific subtypes of breast and lung cancer. This information can be useful in determining the best course of treatment for a s ...
... few transcripts per 10 cells to several thousand transcripts in a single cell. In addition, they look at so many genes that they can actually be used to distinguish between specific subtypes of breast and lung cancer. This information can be useful in determining the best course of treatment for a s ...
PowerPoint slides
... • Complexity increase from transcriptome – Many more proteins than genes – Post-translation from mRNA, amino acid sequences can be modified, changing their function – Protein function is affected by other proteins; they work in complexes ...
... • Complexity increase from transcriptome – Many more proteins than genes – Post-translation from mRNA, amino acid sequences can be modified, changing their function – Protein function is affected by other proteins; they work in complexes ...
An Excel Macro to Visualise Patterns for Chosen Genes
... Can adapt for different combinations of chips to give different profiles Eg a range of organs. Similar in function to GenevestigATor ….but email me if you want to have a go. [email protected] ...
... Can adapt for different combinations of chips to give different profiles Eg a range of organs. Similar in function to GenevestigATor ….but email me if you want to have a go. [email protected] ...
Microarray Services
... individual genes – Different approaches exist for this: • Detect functional enrichment in the DE target list • Detect functional enrichment towards the top of the list when all array targets have been ranked according to the evidence for being differentially expressed • Make the statistical test bet ...
... individual genes – Different approaches exist for this: • Detect functional enrichment in the DE target list • Detect functional enrichment towards the top of the list when all array targets have been ranked according to the evidence for being differentially expressed • Make the statistical test bet ...
HW2-1
... algorithms were developed for differential RNA-seq analysis from the TopHat / Cufflinks developers. They haven’t been published yet, but have already received good feedback from early adopters. Instead of mapping to the whole genome, Kallisto only maps to the RefSeq transcriptome, so can go from FAS ...
... algorithms were developed for differential RNA-seq analysis from the TopHat / Cufflinks developers. They haven’t been published yet, but have already received good feedback from early adopters. Instead of mapping to the whole genome, Kallisto only maps to the RefSeq transcriptome, so can go from FAS ...
Nucleic acid recognition from prokaryotes to eukaryotes: Case
... protein subunits from the DNA in response to NADH. ...
... protein subunits from the DNA in response to NADH. ...
IntroBio520 - Nematode bioinformatics. Analysis tools and data
... and statistics) to make the vast, diverse, and complex life sciences data more understandable and useful. It automates simple but repetitive types of analysis. ...
... and statistics) to make the vast, diverse, and complex life sciences data more understandable and useful. It automates simple but repetitive types of analysis. ...
Macroevolution
... genes are passed from generation to generation (vertical gene transfer). – Hitchhiking genes from other species lead to phylogenetic complexity referred to as lateral gene transfer. ...
... genes are passed from generation to generation (vertical gene transfer). – Hitchhiking genes from other species lead to phylogenetic complexity referred to as lateral gene transfer. ...
RNA-Seq

RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.