The Inherited Metabolic Disorders News
... PDCD is a rare disorder. Pyruvate dehydrogenase (PDH) is an essential and important enzyme in the mitochondrial metabolism. The effects of this deficiency are serious as there is a lack of energy production and build up of lactic acid. PDH catalyzes the oxidation of pyruvate to acetyl CoA (Fig 1). W ...
... PDCD is a rare disorder. Pyruvate dehydrogenase (PDH) is an essential and important enzyme in the mitochondrial metabolism. The effects of this deficiency are serious as there is a lack of energy production and build up of lactic acid. PDH catalyzes the oxidation of pyruvate to acetyl CoA (Fig 1). W ...
Report Organelles in Blastocystis that Blur the
... same organelles is more suggestive of hydrogenosomal metabolism. To clarify the metabolic properties of the Blastocystis MLOs, we used 3330 clusters constructed from our EST data for a comparative BLAST search against the yeast and human mitochondrial proteomes [14, 15]. In addition, the KEGG Automa ...
... same organelles is more suggestive of hydrogenosomal metabolism. To clarify the metabolic properties of the Blastocystis MLOs, we used 3330 clusters constructed from our EST data for a comparative BLAST search against the yeast and human mitochondrial proteomes [14, 15]. In addition, the KEGG Automa ...
List of Possible Bacteria
... fermentation. Respiration uses an external electron acceptor, like oxygen (aerobic respiration) or some other exogenous source (anaerobic respiration) to generate high yields of ATP through complete oxidation of an organic compound. Fermentation, on the other hand, only partially oxidizes the substr ...
... fermentation. Respiration uses an external electron acceptor, like oxygen (aerobic respiration) or some other exogenous source (anaerobic respiration) to generate high yields of ATP through complete oxidation of an organic compound. Fermentation, on the other hand, only partially oxidizes the substr ...
Cell Energy (GPC)
... example of sugar metabolism, the rst metabolic pathway synthesized sugar from smaller molecules, and the other pathway broke sugar down into smaller molecules. These two opposite processesthe rst requiring energy and the second producing energyare referred to as anabolic pathways (building polym ...
... example of sugar metabolism, the rst metabolic pathway synthesized sugar from smaller molecules, and the other pathway broke sugar down into smaller molecules. These two opposite processesthe rst requiring energy and the second producing energyare referred to as anabolic pathways (building polym ...
Lehninger Principles of Biochemistry
... that one solution has ten times the H concentration of the other, but it does not tell us the absolute magnitude of the difference. Figure 2–15 gives the pH of some common aqueous fluids. A cola drink (pH 3.0) or red wine (pH 3.7) has an H concentration approximately 10,000 times that of blood (pH ...
... that one solution has ten times the H concentration of the other, but it does not tell us the absolute magnitude of the difference. Figure 2–15 gives the pH of some common aqueous fluids. A cola drink (pH 3.0) or red wine (pH 3.7) has an H concentration approximately 10,000 times that of blood (pH ...
4-BCH201_Enzymes
... Some enzymes are synthesized in active form and require no chemical groups for activity other than their amino acid residues. Other enzymes are produced in an inactive form due to either: - Presence of excess polypeptide in their structure and is converted to active form after deletion of this part. ...
... Some enzymes are synthesized in active form and require no chemical groups for activity other than their amino acid residues. Other enzymes are produced in an inactive form due to either: - Presence of excess polypeptide in their structure and is converted to active form after deletion of this part. ...
Slide 1
... mitochondrial matrix • The carnitine shuttle moves it into the matrix – Free carnitine is exchanged for acyl carnitine ...
... mitochondrial matrix • The carnitine shuttle moves it into the matrix – Free carnitine is exchanged for acyl carnitine ...
METBIONET GUIDELINES FOR AMINO ACID ANALYSIS.
... haemolysis may be observed. · Free tryptophan may be lost when using sulphosalicylic acid as deproteinising agent; trichloroacetic acid is the deproteinising agent of choice for this amino acid48. · At temperatures greater than 35oC, glutamine is converted to the ninhydrin negative compound pyrrolid ...
... haemolysis may be observed. · Free tryptophan may be lost when using sulphosalicylic acid as deproteinising agent; trichloroacetic acid is the deproteinising agent of choice for this amino acid48. · At temperatures greater than 35oC, glutamine is converted to the ninhydrin negative compound pyrrolid ...
ATP production in brain and liver mitochondria of Fischer
... three nucleotide binding sites that undergo a multiphase, catalytic cycle to produce ATP (43) from ADP and phosphate (i.e., oxidative phosphorylation). Because ATP is tightly bound to the F1 head in the mitochondrial membrane, a large amount of free energy is released during the rapid hydrolysis of ...
... three nucleotide binding sites that undergo a multiphase, catalytic cycle to produce ATP (43) from ADP and phosphate (i.e., oxidative phosphorylation). Because ATP is tightly bound to the F1 head in the mitochondrial membrane, a large amount of free energy is released during the rapid hydrolysis of ...
The Endogenous Citric Acid-Cycle Intermediates and Amino Acids
... solution at 600. This solution was used for one of the following specific methods of estimation. Succinate and fumarate were measured by a method of W. Bartley & B. Notton not published previously. The method involved the conversion of the two compounds into malate by the use of succinoxidase and fu ...
... solution at 600. This solution was used for one of the following specific methods of estimation. Succinate and fumarate were measured by a method of W. Bartley & B. Notton not published previously. The method involved the conversion of the two compounds into malate by the use of succinoxidase and fu ...
Fulvic Acids - Australian Humates
... Transminase enzymes are important in the production of various amino acids. ...
... Transminase enzymes are important in the production of various amino acids. ...
O - Portland State University
... some of the volatiles on the early Earth were there because of the gaseous planets, Neptune, Uranus, Saturn, and particularly Jupiter the massive gravity of this planet helped to “clean up” the protoplanetary debris in the Solar System the debris either got ejected from the Solar System or condensed ...
... some of the volatiles on the early Earth were there because of the gaseous planets, Neptune, Uranus, Saturn, and particularly Jupiter the massive gravity of this planet helped to “clean up” the protoplanetary debris in the Solar System the debris either got ejected from the Solar System or condensed ...
Specific Growth Inhibition by Acetate of an Escherichia coli Strain
... metabolites as carbon source when overproduced. To investigate the role of Era, the gene expression in the cells overproducing Era-dE was examined by DNA microarray analysis. The expression of lipA and nadAB, which are involved in lipoic acid synthesis and NAD synthesis, respectively, was found to b ...
... metabolites as carbon source when overproduced. To investigate the role of Era, the gene expression in the cells overproducing Era-dE was examined by DNA microarray analysis. The expression of lipA and nadAB, which are involved in lipoic acid synthesis and NAD synthesis, respectively, was found to b ...
Oxygen and the Growth and Metabolism of
... Servo Recorder (Heath (Gloucester) Ltd; Model EUW-2oA) and the E h and pH of the culture were measured with a Radiometer pH meter (Model 25). The growth chamber in the culture vessel was sterilized by overnight treatment with alkaline sodium hypochlorite, and before use was thoroughly washed with st ...
... Servo Recorder (Heath (Gloucester) Ltd; Model EUW-2oA) and the E h and pH of the culture were measured with a Radiometer pH meter (Model 25). The growth chamber in the culture vessel was sterilized by overnight treatment with alkaline sodium hypochlorite, and before use was thoroughly washed with st ...
UvA-DARE (Digital Academic Repository)
... galactose-proton symport system for glucose uptake, exhibited significantly altered metabolic patterns relative to the parent strain PPA305 which retains PTS activity. Replacement of a PTS uptake system by the galactoseproton symport system is expected to lower the carbon flux to pyruvate in both ae ...
... galactose-proton symport system for glucose uptake, exhibited significantly altered metabolic patterns relative to the parent strain PPA305 which retains PTS activity. Replacement of a PTS uptake system by the galactoseproton symport system is expected to lower the carbon flux to pyruvate in both ae ...
PDF
... may operate in vivo, we may remember the influence of the relative concentrations of oxidized and reduced NAD, as well as the influence of hydrogen-ion concentration (Tobin, 1964). The immediate accumulation of pyruvic acid fits well into the hypothesis advanced by Cohen (1955) by showing that the t ...
... may operate in vivo, we may remember the influence of the relative concentrations of oxidized and reduced NAD, as well as the influence of hydrogen-ion concentration (Tobin, 1964). The immediate accumulation of pyruvic acid fits well into the hypothesis advanced by Cohen (1955) by showing that the t ...
Enzymes for Pharma Applications
... Fungal hemicellulase and cellulase : Fungal hemi-cellulase and cellulase enzyme system contains many unique side activities, which help in rapid hydrolysis of cellulose, hemicellulose and beta-glucan polymers in food. The gummy substances take up a lot of water and swell up to about ten times, thus ...
... Fungal hemicellulase and cellulase : Fungal hemi-cellulase and cellulase enzyme system contains many unique side activities, which help in rapid hydrolysis of cellulose, hemicellulose and beta-glucan polymers in food. The gummy substances take up a lot of water and swell up to about ten times, thus ...
NOTE Preliminary organic compound analysis of microparticles returned from
... opportunity to examine the occurrence of organic matter on the surface of an asteroid without terrestrial contaminants. Asteroid 25143 Itokawa is an S-type asteroid, which is likely to be a parent body of LL5-6 ordinary chondrites (Abe et al., 2006; Okada et al., 2006). The collected particles consi ...
... opportunity to examine the occurrence of organic matter on the surface of an asteroid without terrestrial contaminants. Asteroid 25143 Itokawa is an S-type asteroid, which is likely to be a parent body of LL5-6 ordinary chondrites (Abe et al., 2006; Okada et al., 2006). The collected particles consi ...
Amino Acid - forte elements
... The body of a 70-kilogram man contains about 11 kilograms of protein, nearly half (~43%) of which is present as skeletal muscle. The skin and blood each account for approximately 15 percent of protein, while the metabolically active visceral tissues and other organs, such as the brain, lungs, heart, ...
... The body of a 70-kilogram man contains about 11 kilograms of protein, nearly half (~43%) of which is present as skeletal muscle. The skin and blood each account for approximately 15 percent of protein, while the metabolically active visceral tissues and other organs, such as the brain, lungs, heart, ...
Changes in the Amino Acid and Protein Content of
... In this study, the fungi, caused increases in protein when compared to the control. The significant increase (P=0.05) in protein content by Fusarium oxysporum and Macrophomina phaseolina could have resulted from slight protein synthesis of enzyme proteins or other constituents[10] (Kuo et al., 1995) ...
... In this study, the fungi, caused increases in protein when compared to the control. The significant increase (P=0.05) in protein content by Fusarium oxysporum and Macrophomina phaseolina could have resulted from slight protein synthesis of enzyme proteins or other constituents[10] (Kuo et al., 1995) ...
Citric acid cycle
The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.