• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Blood Transfusion ok320 KB
Blood Transfusion ok320 KB

... Cryopresipitate Coagulation factor concentrates Immunglobulin preperations Albumin others ...
Physiology of Blood I. Components, Characteristics, Functions of
Physiology of Blood I. Components, Characteristics, Functions of

... related to "mast cells" of connective tissue BOTH release Histamine with "IgE" signal antihistamine - blocks the action of Histamine in response to infection or allergic antigen ...
The first characterization of two type I interferons in turbot
The first characterization of two type I interferons in turbot

... showing different properties. Whereas Ifn1 reflected a clear antiviral activity (overexpression of ISGs and protection against viral haemorrhagic septicaemia virus), Ifn2 was not able to induce this response, although both transcripts were up-regulated after viral challenge. On the other hand, turbo ...
Immunomodulatory functions of type I interferons
Immunomodulatory functions of type I interferons

MCB 169: Fall 2015
MCB 169: Fall 2015

... Antibodies and antigens (Chapter 5) Antigen receptors and MHC molecules (Chapter 6) Antigen presentation (Chapter 6) Ig genes and the generation of diversity (Chapter 8) B cell development and tolerance (Chapter 8) T cell development and tolerance (Chapter 8) B cell activation (Chapter 7 and 11) Aff ...
Full Text PDF
Full Text PDF

... The Epstein–Barr virus (EBV) is one of the most common human viruses, infecting more than 90% of the world’s adult population. In some individuals the interplay between EBV replication, latency and immune control can be disrupted and evokes prolonged proliferation of EBV-infected lymphocytes and the ...
A Single-step Purification of the Saccharomyces cerevlslae
A Single-step Purification of the Saccharomyces cerevlslae

... authors for isolation of recombinant Mtn p are arduous, requiring many conventional column chromatogaphic steps and yielding low amounts of protein because of its toxicity to bacteria. To overcome these problems, we have constructed a new expression plasmid coding for the yeast specificitY fa ctor a ...
VOL.LVIII, suppl. XIII, 162 SECTIO D 2003
VOL.LVIII, suppl. XIII, 162 SECTIO D 2003

... reactions of non-specific and specific organism immune systems were balanced, with essential predominance of the macrophage-cell reaction and affected section of immune response. The balance between hypersensitivity reactions of slow and urgent types was normal. All the subjects had essentially dist ...
Endothelial Nitric Oxide Synthase - Arteriosclerosis, Thrombosis
Endothelial Nitric Oxide Synthase - Arteriosclerosis, Thrombosis

... abnormality of eNOS function. For example, models of diabetes, hypertension, and atherosclerosis have been associated with reduced tissue BH4 levels, increased superoxide generation, and impaired endothelial function.15–17 As explained before, uncoupling of eNOS implies that the endothelial cell swi ...
Enterovirus typing by immune electronmicroscopy
Enterovirus typing by immune electronmicroscopy

... results. The IEM method is convenient and has considerable savings in time and reagents. ...
assessment of physiological stress in periparturient cows and
assessment of physiological stress in periparturient cows and

... and biochemical parameters such as blood glucose level (BGL), total plasma protein (TPP), lymphocyte:neutrophil ratio and mitogen induced lymphocyte proliferative response. Blood samples were collected from six cows in four periods, namely., 3 days prior to parturition, on the day of parturition, an ...
PDF
PDF

... tissues does not necessarily reveal the potential or actual functions of these antigens. In the case of H-2 antigens the function remains an enigma, even though a number of hypothetical models have been proposed which view H-2 antigens as playing a role in cell-cell recognition (Edelman, 1976; Bonne ...
Doctoral thesis from the Department of Immunology,
Doctoral thesis from the Department of Immunology,

... incidence of 2 million new cases per year (0.5 million of visceral leishmaniasis (VL) and l.5 million of cutaneous leishmaniasis (CL). VL causes an estimated more than 50 000 deaths annually and 2 357 000 disability-adjusted life years lost, placing leishmaniasis ninth in a global analysis of infect ...
the 30th Annual Conference of the
the 30th Annual Conference of the

LFA-1/ICAM-1 Interaction Lowers the Threshold of B Cell Activation by Facilitating
LFA-1/ICAM-1 Interaction Lowers the Threshold of B Cell Activation by Facilitating

... hormone receptors, and lipids have been identified as autoantigens (Lernmark, 2001). However, it is still unknown how B cells become activated by these membrane antigens. Thus, membrane antigen recognition is likely to play an important role in determining the fate of B cells in vivo during an immun ...
Canine Immune-Mediated Thrombocytopenia
Canine Immune-Mediated Thrombocytopenia

... how complex and variable ITP is, the treatment of each patient is based on the individual presentation. Long term treatment involves the use of immunosuppressive medications and other medications based on clinical signs. Animals are often on medications for 6-8 months after the time of presentation. ...
Innate Immune Cells in Liver Inflammation
Innate Immune Cells in Liver Inflammation

... pathogens and damaged cells and to chromatin in nuclear DNA-histone complexes, thus acts as an opsonin for various pathogens and activator of the complement system by binding to Fc receptors. Interaction of CRP with Fc receptors induces the production of proinflammatory cytokines that further enhanc ...
CARMA1 Is Critical for the Development of Allergic Airway
CARMA1 Is Critical for the Development of Allergic Airway

... CARMA1 in the regulation of the adaptive immune response through its actions in lymphocytes, and suggests that targeted inhibition of CARMA1 would provide a novel means of inhibiting NF-␬B activation in lymphocytes. In addition, because CARMA1 activation is regulated by protein kinases, it may be qu ...
CD4 § T-Cells from Mice Immunized to
CD4 § T-Cells from Mice Immunized to

... Tumor-immune CD4 § T-Ceils but Not CD8 § T-Cells Show Specific Proliferation to Tumor-pulsed D C . W h e n C D 4 + and C D 8 § T-cell subgroups were each prepared from both naive and tumori m m u n e mice, only t u m o r - i m m u n e C D 4 + T-cells d e m o n s t r a t e d specific proliferation w ...
Regression of Nevi After Candida Injection for the Treatment of
Regression of Nevi After Candida Injection for the Treatment of

... immunomodulating technique has been conducted using paramxyovirus and trichophyton. Other immune modulators include imiquimod and contact sensitizers such as diphencyprone and squaric acid dibutyl ester. There are accounts of Candida immunotherapy inducing vitiligo (2). The induction of vitiligo may ...
Blood and Blood Component Therapy
Blood and Blood Component Therapy

... weakly reacting antibodies showing dosage. Dosage refers to stronger expression of the antigen when the individual inherits the gene homozygously, vs. heterozygously. It is important that antibodies to these antigens are ruled out on homozygous reagent cells, since a heterozygous cell may be nonreac ...
INVESTIGATING ANTIGEN PRESENTATION BY INACTIVATED LYMPHOCYTIC CHORIOMENINGITIS VIRUS AND BY
INVESTIGATING ANTIGEN PRESENTATION BY INACTIVATED LYMPHOCYTIC CHORIOMENINGITIS VIRUS AND BY

... presenting cells (pAPCs) present foreign antigen on their cell surface to a naïve T cell resulting in T cell priming and cytotoxic CD8+ T lymphocyte (CTL) activation. Since activation of CTLs is very poor in response to killed pathogens, we wanted to examine how CTL activation differs in response to ...
Dialogue between skin microbiota and immunity
Dialogue between skin microbiota and immunity

... fully the functional and taxonomic landscape of the human skin microbiome as shaped by the local biogeography (16). This inclusive, relational analysis of the bacterial, fungal, and viral communities showed not only site specificity but also unique individual signatures. Similar to results from ampl ...
- Journal of Clinical Investigation
- Journal of Clinical Investigation

... high levels of B cell trophic and chemotactic mediators that parallel findings in classic autoantibody diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, and Sjögren’s syndrome) (27–30). Nonetheless, the precise roles of autoantibodies and neoantigens in the development and/or progr ...
Predicting pathogen-specific CD8 T cell immune responses
Predicting pathogen-specific CD8 T cell immune responses

... are based on live viruses and stay contraindicated for some people [19, 20, 21]. Moreover vaccinia virus could also be used as a platform for the design of vaccines directed against other pathogens [4]. Listeria monocytogenes, a Gram-positive bacteria, causes disease mainly in immunocompromised huma ...
< 1 ... 94 95 96 97 98 99 100 101 102 ... 553 >

Immunomics

Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report