Immunotoxicity - KSU Faculty Member websites
... ultraviolet B UVR ultraviolet radiation VCAM vascular cell adhesion molecule VLA very late antigen ...
... ultraviolet B UVR ultraviolet radiation VCAM vascular cell adhesion molecule VLA very late antigen ...
Clinical pathogenesis of typhoid fever
... lumenal from invasive microbes. This allows for an appropriate response to invasive enteric pathogens, such as NTS, by triggering exudative inflammation [25, 26]. Because a small number of PRRs triggers the bulk of transcriptional changes through activation of the transcription factors NFκB, AP-1 an ...
... lumenal from invasive microbes. This allows for an appropriate response to invasive enteric pathogens, such as NTS, by triggering exudative inflammation [25, 26]. Because a small number of PRRs triggers the bulk of transcriptional changes through activation of the transcription factors NFκB, AP-1 an ...
Soluble β-glucan and heparin as modulators of the immune
... possible cancer therapies is needed. One treatment option is therapeutic vaccination, where endogenous antibodies against tumor-associated proteins are generated through carefully developed immunization strategies used in combination with potent adjuvant mixtures. This putative cancer therapy has th ...
... possible cancer therapies is needed. One treatment option is therapeutic vaccination, where endogenous antibodies against tumor-associated proteins are generated through carefully developed immunization strategies used in combination with potent adjuvant mixtures. This putative cancer therapy has th ...
Chimeric CLL-1 Antibody Fusion Proteins Containing Granulocyte
... in animal model systems.4-9 Because of the toxicity of systemically administered cytokines, however, methods are needed to target these biologically potent immunologic mediators to the tumor site. One approach, gene transfer, has demonstrated that tumor cells engineered to secrete cytokines stimulat ...
... in animal model systems.4-9 Because of the toxicity of systemically administered cytokines, however, methods are needed to target these biologically potent immunologic mediators to the tumor site. One approach, gene transfer, has demonstrated that tumor cells engineered to secrete cytokines stimulat ...
When NF-kB is inhibited
... Role as regulator of Immune responses Role as regulator of apoptosis Regulation Mechanism As target for Therapy Conclusions ...
... Role as regulator of Immune responses Role as regulator of apoptosis Regulation Mechanism As target for Therapy Conclusions ...
Corticotropin-Releasing Hormone and Its Structurally Related
... however, indicates that mast cells also secrete proinflammatory cytokines (14, 15), such as IL-6 (16) and are involved in neuroinflammatory processes (17). These findings have prompted the speculation that mast cells may have a much more versatile role than previously suspected (18, 19). It has been ...
... however, indicates that mast cells also secrete proinflammatory cytokines (14, 15), such as IL-6 (16) and are involved in neuroinflammatory processes (17). These findings have prompted the speculation that mast cells may have a much more versatile role than previously suspected (18, 19). It has been ...
Control of coronavirus infection through
... immune responses.1 Signaling through the type I IFN receptor leads to the activation of a particular set of genes, including protein kinase R, and Mx proteins,2 which exert potent direct antiviral effects. Other type I IFN–stimulated gene products, such as IFN-␥, activate downstream elements of the ...
... immune responses.1 Signaling through the type I IFN receptor leads to the activation of a particular set of genes, including protein kinase R, and Mx proteins,2 which exert potent direct antiviral effects. Other type I IFN–stimulated gene products, such as IFN-␥, activate downstream elements of the ...
I , Apr. 2005, p. 2012–2019 Vol. 73, No. 4 ⫹0 doi:10.1128/IAI.73.4.2012–2019.2005
... there is also evidence from various systems that melanins have immunomodulatory properties, which conceivably could contribute to virulence by altering immune responses. To investigate the effect of melanin on the immune response, we compared the murine pulmonary responses to infection with melanize ...
... there is also evidence from various systems that melanins have immunomodulatory properties, which conceivably could contribute to virulence by altering immune responses. To investigate the effect of melanin on the immune response, we compared the murine pulmonary responses to infection with melanize ...
NIH Public Access
... generated a wave of disappointment in recent clinical trials [3]. A central motivation for the development of these agents was to attenuate or eliminate the devastating side effects of traditional MTAs. Unfortunately, targeted antimitotics have thus far not lived up to their promise despite billions ...
... generated a wave of disappointment in recent clinical trials [3]. A central motivation for the development of these agents was to attenuate or eliminate the devastating side effects of traditional MTAs. Unfortunately, targeted antimitotics have thus far not lived up to their promise despite billions ...
Myasthenia gravis: A comprehensive review of immune
... Ectopic GCs developing in the thymus are primarily associated with AChR-MG but not MuSK-MG [25,43]. Patients with thymic follicular hyperplasia typically display elevated serum AChR antibody titers [44]. In these patients, the thymus is one site of antiAChR production [45e47]. It is worth noting tha ...
... Ectopic GCs developing in the thymus are primarily associated with AChR-MG but not MuSK-MG [25,43]. Patients with thymic follicular hyperplasia typically display elevated serum AChR antibody titers [44]. In these patients, the thymus is one site of antiAChR production [45e47]. It is worth noting tha ...
Sample questions for EAACI
... (B) Cross reactive carbohydrate determinants (C) Allergen homologous of Bet v 1 (D) Allergen homologous of Phl p1 (E) Lipid transfer protein (LTP) like Pru p3 Correct answer: E 16. A 19-years old boy is looking for you help as he suffers from urticaria since more than a years. He reports that the wh ...
... (B) Cross reactive carbohydrate determinants (C) Allergen homologous of Bet v 1 (D) Allergen homologous of Phl p1 (E) Lipid transfer protein (LTP) like Pru p3 Correct answer: E 16. A 19-years old boy is looking for you help as he suffers from urticaria since more than a years. He reports that the wh ...
The Vital 90 Days and Why It`s Important to a Successful Lactation
... Immunity encompasses a number of complex interactions that are designed to protect the animal from infection by a number of microbial organisms. The immune system is characterized by two primary branches: acquired immunity and innate immunity. Acquired immunity refers to the portion of the immune sy ...
... Immunity encompasses a number of complex interactions that are designed to protect the animal from infection by a number of microbial organisms. The immune system is characterized by two primary branches: acquired immunity and innate immunity. Acquired immunity refers to the portion of the immune sy ...
Publication : Down syndrome and coexistent autoimmune
... In lymphoid cells derived from patients with DS, lymphocyte-function-associated antigen-1 (LFA-1) is overexpressed (Murphy et al. 1993). This adhesion receptor plays a crucial role in the trafficking and activation of leukocytes. Accordingly, cells with trisomy 21 have increased sensitivity to inter ...
... In lymphoid cells derived from patients with DS, lymphocyte-function-associated antigen-1 (LFA-1) is overexpressed (Murphy et al. 1993). This adhesion receptor plays a crucial role in the trafficking and activation of leukocytes. Accordingly, cells with trisomy 21 have increased sensitivity to inter ...
Diefenbach, A., E.R. Jensen, A.M. Jamieson, and D.H. Raulet. 2001. Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature 413:165-171.
... Natural killer (NK) cells attack many tumour cell lines, and are thought to have a critical role in anti-tumour immunity1±7; however, the interaction between NK cells and tumour targets is poorly understood. The stimulatory lectin-like NKG2D receptor8±13 is expressed by NK cells, activated CD8+ T ce ...
... Natural killer (NK) cells attack many tumour cell lines, and are thought to have a critical role in anti-tumour immunity1±7; however, the interaction between NK cells and tumour targets is poorly understood. The stimulatory lectin-like NKG2D receptor8±13 is expressed by NK cells, activated CD8+ T ce ...
Mucosal candidiasis elicits NF-κB activation, proinflammatory gene
... zebrafish swimmbladder infection model, we show dimorphic fungal growth, both localized and tissue-wide epithelial NF-κB activation, induction of NF-κB -dependent proinflammatory genes, and strong neutrophilia. Consistent with density-dependence models of host response based primarily on tissue cult ...
... zebrafish swimmbladder infection model, we show dimorphic fungal growth, both localized and tissue-wide epithelial NF-κB activation, induction of NF-κB -dependent proinflammatory genes, and strong neutrophilia. Consistent with density-dependence models of host response based primarily on tissue cult ...
Mastitis, Mammary Gland Immunity, and Nutrition
... acid radicals. These fatty acid radicals can react with other fatty acids and produce a chain reaction. ...
... acid radicals. These fatty acid radicals can react with other fatty acids and produce a chain reaction. ...
Monocyte-Activation Phenotypes Are Associated With Biomarkers of
... (ie, structured treatment interruptions, sequential monotherapy, or dual protease inhibitor therapy) that may not reflect how current standards of care influence ongoing immune activation. The SUN Study is a prospective, observational study of a contemporary cohort of HIV-infected adults at low risk f ...
... (ie, structured treatment interruptions, sequential monotherapy, or dual protease inhibitor therapy) that may not reflect how current standards of care influence ongoing immune activation. The SUN Study is a prospective, observational study of a contemporary cohort of HIV-infected adults at low risk f ...
Back to A+P II
... This is the outline I use for my lectures in A&PII. Use your own lecture notes, this outline and the objectives after each section in the outline as a study guide. You might find it helpful to put your own notes into outline order. Test questions will come from material covered in lecture. Chapters, ...
... This is the outline I use for my lectures in A&PII. Use your own lecture notes, this outline and the objectives after each section in the outline as a study guide. You might find it helpful to put your own notes into outline order. Test questions will come from material covered in lecture. Chapters, ...
Immunomodulatory Roles of Lymphatic Vessels
... (e.g., the site of infection) and had sufficient time to upregulate costimulatory receptors (18, 19). This further rationalizes why lymph flow may be critical for fine-tuning immune responses and to avoid autoimmune reactions in the process of activating effective immunity against pathogens. In additio ...
... (e.g., the site of infection) and had sufficient time to upregulate costimulatory receptors (18, 19). This further rationalizes why lymph flow may be critical for fine-tuning immune responses and to avoid autoimmune reactions in the process of activating effective immunity against pathogens. In additio ...
