Scientific Report 2011 - IRB
... biomedical research. The average impact factor of all these publications is exceptional (11,2) without even having included the last two publications just newly accepted into Nature and Molecular Cell. In addition to these prolific, high quality publications, their recognition is also testified by edi ...
... biomedical research. The average impact factor of all these publications is exceptional (11,2) without even having included the last two publications just newly accepted into Nature and Molecular Cell. In addition to these prolific, high quality publications, their recognition is also testified by edi ...
Novel technologies and emerging biomarkers for personalized
... essential to perform biomarker studies to further characterize these different classes of tumors and provide guidance for therapeutic strategies. Improved high-throughput technologies are providing feasible tools for analyzing the mutation antigen profile, the gene signature and epigenetic modificat ...
... essential to perform biomarker studies to further characterize these different classes of tumors and provide guidance for therapeutic strategies. Improved high-throughput technologies are providing feasible tools for analyzing the mutation antigen profile, the gene signature and epigenetic modificat ...
The Current Status of Gene Therapy for Prostate Cancer
... cell phenotype over the patient’s lifetime.18 Furthermore, this can be advantageous in tumor vaccine strategies in which a steady level of gene expression may enhance efficacy. In contrast, adenovirus, vaccinia, and liposomal vector transfer are episomal methods: the transferred gene is expressed wi ...
... cell phenotype over the patient’s lifetime.18 Furthermore, this can be advantageous in tumor vaccine strategies in which a steady level of gene expression may enhance efficacy. In contrast, adenovirus, vaccinia, and liposomal vector transfer are episomal methods: the transferred gene is expressed wi ...
Signal Transduction ? ? ? ? ? ? TCR associates with the CD3 Complex
... Immunosuppressive drugs block NF-AT activation ...
... Immunosuppressive drugs block NF-AT activation ...
JDRF Cure Research – Halting the autoimmune process and
... Implanting encapsulated beta cells in a person with T1D could make them independent of external insulin use, but several hurdles exist. The key challenges are keeping the cells alive with oxygen and nutrients and protecting them from further immune attack. JDRF-supported researchers at the Universit ...
... Implanting encapsulated beta cells in a person with T1D could make them independent of external insulin use, but several hurdles exist. The key challenges are keeping the cells alive with oxygen and nutrients and protecting them from further immune attack. JDRF-supported researchers at the Universit ...
ILO`s and lecture objectives-HMIM 224(2013
... Identify the role of cell receptors in self-recognition and epitope interaction. Describe the importance of Land-Steiner’s experiment in identification of immunogen and Hapten. Compare between T-cell dependent and T-cell independent antigens. ...
... Identify the role of cell receptors in self-recognition and epitope interaction. Describe the importance of Land-Steiner’s experiment in identification of immunogen and Hapten. Compare between T-cell dependent and T-cell independent antigens. ...
JDRF Research Top 10 Advances of FY2012 JDRF Cure Research
... Implanting encapsulated beta cells in a person with T1D could make them independent of external insulin use, but several hurdles exist. The key challenges are keeping the cells alive with oxygen and nutrients and protecting them from further immune attack. JDRF-supported researchers at the Universit ...
... Implanting encapsulated beta cells in a person with T1D could make them independent of external insulin use, but several hurdles exist. The key challenges are keeping the cells alive with oxygen and nutrients and protecting them from further immune attack. JDRF-supported researchers at the Universit ...
Humoral response against myelin associated glycoprotein reflects
... titers and clinical stage of the disease measured on theHoehnYahr scale. Taking into consideration Monahan’s hypothesis, one could expect differences in antibody titers among subgroups of patients with different stages of the disease. It is worth noting, however, that Burke et al. [23] did not find ...
... titers and clinical stage of the disease measured on theHoehnYahr scale. Taking into consideration Monahan’s hypothesis, one could expect differences in antibody titers among subgroups of patients with different stages of the disease. It is worth noting, however, that Burke et al. [23] did not find ...
Invest Ophthalmol Vis Sci 1999 - Weizmann Institute of Science
... PURPOSE. Idiopathic inflammation of the cornea, keratitis, has been proposed to result from an autoimmune process, but thus far no convenient animal model of keratitis exists. An attempt was made to establish an animal model for keratitis, to investigate possible autoimmune mechanisms. METHODS. T-ce ...
... PURPOSE. Idiopathic inflammation of the cornea, keratitis, has been proposed to result from an autoimmune process, but thus far no convenient animal model of keratitis exists. An attempt was made to establish an animal model for keratitis, to investigate possible autoimmune mechanisms. METHODS. T-ce ...
A functional DC cross talk promotes human ILC homeostasis in
... nuclear receptor RORgt and produce IL-17A and IL-22 after stimulation. ILC3s play important roles in maintaining barrier surfaces (especially mucosal sites) and for protection against infections by fungi and extracellular bacteria. Interestingly, ILC3s are deregulated in inflammatory conditions (irr ...
... nuclear receptor RORgt and produce IL-17A and IL-22 after stimulation. ILC3s play important roles in maintaining barrier surfaces (especially mucosal sites) and for protection against infections by fungi and extracellular bacteria. Interestingly, ILC3s are deregulated in inflammatory conditions (irr ...
The role of the thymus in allogeneic hematopoietic stem cell
... individuals and during acute GVHD. The top panel displays a scheme for thymus function in young individuals. The HSC-derived lymphoid progenitors ( ) enter the thymic microenvironment where they are committed to the T-cell lineage. Mouse cells at early stages of this development are phenotypically c ...
... individuals and during acute GVHD. The top panel displays a scheme for thymus function in young individuals. The HSC-derived lymphoid progenitors ( ) enter the thymic microenvironment where they are committed to the T-cell lineage. Mouse cells at early stages of this development are phenotypically c ...
Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway
... local research ethics committee (Newcastle and North Tyneside Local Regional Ethics Committee, Newcastle upon Tyne, UK) and informed written consent was obtained from all study patients. ...
... local research ethics committee (Newcastle and North Tyneside Local Regional Ethics Committee, Newcastle upon Tyne, UK) and informed written consent was obtained from all study patients. ...
ANTIGEN PRESENTATION and the MHC
... Production of antibody to most antigens requires not just B cells but also T cells. B cells take up antigen, then B cells process antigen and display processed peptides on MHC class II molecules. This process activates the B cell to make B7. T cells recognize MHC presented antigen and B7 co-stimulat ...
... Production of antibody to most antigens requires not just B cells but also T cells. B cells take up antigen, then B cells process antigen and display processed peptides on MHC class II molecules. This process activates the B cell to make B7. T cells recognize MHC presented antigen and B7 co-stimulat ...
TLR3 Signaling in Human BDCA-3 Dendritic Cells Results in the
... The immune system consists of an intricate network of cells that are capable of detecting both foreign and selfantigens. The process of eliminating foreign antigens and the ability to tolerate self-antigens occur within both innate and adaptive immunity. Innate immunity is shared by all multi-cellul ...
... The immune system consists of an intricate network of cells that are capable of detecting both foreign and selfantigens. The process of eliminating foreign antigens and the ability to tolerate self-antigens occur within both innate and adaptive immunity. Innate immunity is shared by all multi-cellul ...
Immunology Coursebook 2016/17
... laboratory classes, examinations, clinical attendance, professional training placements, and so on as appropriate. There is no intrinsic relationship between the credit volume of a module and its level of difficulty. The European norm for full-time study over one academic year is 60 credits. ECTS cr ...
... laboratory classes, examinations, clinical attendance, professional training placements, and so on as appropriate. There is no intrinsic relationship between the credit volume of a module and its level of difficulty. The European norm for full-time study over one academic year is 60 credits. ECTS cr ...
Transfer Factor - GlobalSuccess4Life.com
... destroy it. This provides protection against bacteria, fungi, parasites, and toxins. It can also help prevent a virus from entering a cell. A transfer factor preparation can speed up this process since it already has information on hundreds of these invaders. Your immune system doesn't have to learn ...
... destroy it. This provides protection against bacteria, fungi, parasites, and toxins. It can also help prevent a virus from entering a cell. A transfer factor preparation can speed up this process since it already has information on hundreds of these invaders. Your immune system doesn't have to learn ...
Mesenchymal Stem Cell Population Derived from
... shown with a variety of methods, their ability to sense and respond to environmental cues, to impact immune cell function, and to function therapeutically in vivo have not been explored in as much detail as they have been for BM-MSCs. In this study, we describe a novel and efficient method for gener ...
... shown with a variety of methods, their ability to sense and respond to environmental cues, to impact immune cell function, and to function therapeutically in vivo have not been explored in as much detail as they have been for BM-MSCs. In this study, we describe a novel and efficient method for gener ...
Variable expression of immunoreactive surface proteins of
... Despite accumulating data implicating Propionibacterium acnes in a variety of diseases, its precise role in infection remains to be determined. P. acnes antigen-specific CD4+ T cells are present in early inflamed acne lesions and may be involved in the inflammatory response; however, little is known ...
... Despite accumulating data implicating Propionibacterium acnes in a variety of diseases, its precise role in infection remains to be determined. P. acnes antigen-specific CD4+ T cells are present in early inflamed acne lesions and may be involved in the inflammatory response; however, little is known ...
Enhancement of natural killer (NK) cell cytotoxicity by fever
... component in the regulation of NK cell function, one that appears to significantly enhance the cytotoxic activity of peripheral blood-derived, human NK cells against tumor targets. In a series of experiments, freshly isolated human NK cells from the peripheral blood of normal donors were cocultured ...
... component in the regulation of NK cell function, one that appears to significantly enhance the cytotoxic activity of peripheral blood-derived, human NK cells against tumor targets. In a series of experiments, freshly isolated human NK cells from the peripheral blood of normal donors were cocultured ...
