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Role of BBB in inflammation, seizures, strokes, TBI, infections
Role of BBB in inflammation, seizures, strokes, TBI, infections

... of a conventional lymphatic system, may become available to recognition by the action of APCs. Thus during inflammatory conditions, microglia and macrophages, endothelial cells of the BBB, and epithelial cells of the choroid plexus are all capable of presenting antigens to T cells (1,17– 19). These ...
Immune System
Immune System

... • Helper T cells aid both responses Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
The clonal selection hypothesis is a widely accepted
The clonal selection hypothesis is a widely accepted

... results in immunity to that antigen. In 1958, Sir Gustav Nossal and Joshua Lederberg showed that one B cell always produces only one antibody, which was the first evidence for clonal selection theory. B cells exist as clones. All B cells derive from a particular cell, and as such, the antibodies and ...
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video slide

... • Helper T cells aid both responses Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
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... • prevailing antibody of primary immune response • high-effective agglutinant and cytolytic agent • usually isohaemagglutinins and natural antibodies ...
Course of Immunology
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Course of Immunology
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IMMUNOLOGY SIMPLIFIED —from AIDS to ZZZZZZ
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... mechanisms that allow the body to recognize materials as foreign or abnormal and to neutralize or eliminate those foreign materials. ...


Part I T lymphocyte - Shandong University
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Chapter 18 Textbook Review pg. 621-622 (#1
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slides - Smith Lab

... Inflammation leads to increase chemokine production • <24 hrs Neutrophils and immature Macrophages enter the cornea • 24-48 hrs Macrophages and Dendritic cells mature • 48 hrs NK cells enter the cornea • >48 hrs Dendritic cells travel to the DLN • 3-7 days Dendritic Cells Prime the T cell responses ...
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205 كطب علم المناعة

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Modeling the Immune System

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Immunology for the Rheumatologist
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Clinical immunology
Clinical immunology

... lymphocyte proliferation by treatment with polyclonal mitogens or specific bacterial antigen, measurements of apoptosis, ELISA tests for cytokines identification, phagocytosis evaluation techniques. The second part of the course will include lectures on clinical immunology (starting next year). The ...
Immune System - Uplift Education
Immune System - Uplift Education

... healthy body cells • Agglutination / Precipitation: clumping of antibody-bound particles, which makes them unable to enter healthy cells and more likely to be eaten by phagocytes • Increased phagocytosis – the presence of antibodies ‘flags’ a pathogen, increasing the chance that it will be eaten by ...
Nature Reviews Immunology
Nature Reviews Immunology

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Lymphatic System and Immunity
Lymphatic System and Immunity

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Understanding the Immune System
Understanding the Immune System

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VMB 673 Comparative Immunology Syllabus 2013 Revised Cat 2
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... C. Soluble antigen receptors in other organisms ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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