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Immunology. Mucosal and Body Surface Defences Brochure
Immunology. Mucosal and Body Surface Defences Brochure

... 2.2 Innate immune receptors and cells, 20 2.3 TLRs and pattern recognition, 22 2.4 TLR signalling in response to LPS, 23 2.5 Peptidoglycan and Nods, 24 2.6 Nod–like receptors recognize PAMPs and DAMPs, 25 2.7 Damage associated molecular patterns (DAMPs), 26 2.8 Complement proteins perform several in ...
Immunodeficiencies HIV/AIDS
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... Window period = time between infection, Ab detection: An infected person can infect others within 2 weeks of initial HIV exposure, at a time well before anti-HIV Ab’s can be detected. Average time from initial infection to AIDS is about 10 years, though this rate of development is lengthening with ...
Ch. 43 immune system
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... • The heart is made of muscle cells. • Every cell needs oxygen and glucose to make energy (respiration) • The blood transports oxygen and glucose to every cell • Blood leaves the heart under high pressure and returns under low pressure • Veins carry blood into the heart • Arteries carry blood away f ...
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... Undifferentiated lymphocytes that reach the thymus become T cells; B cells are thought to mature in the bone marrow. Both B and T cells reside in lymphatic organs. T-Cells and the Cellular Immune Response: _______ cells attack foreign, antigen-bearing cells, such as bacteria, by direct cell-to-cell ...
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Download PDF
Download PDF

... KEYWORDS: Microfluidics, Cell-Pairing, Immune Cells, Ratiometric Imaging, Fura-2, Calcium INTRODUCTION Many immune responses are mediated by cell-cell interactions. In particular, cytotoxic T cells form conjugates with pathogenic and cancer cells in order to fight disease. Moreover, T cell maturatio ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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