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Synthetic Nanovaccines
Synthetic Nanovaccines

... in mice also are present in humans with Parkinson’s disease. The cause of Parkinson’s disease — which affects more than 4 million people worldwide — is the loss of neurons that produce dopamine, a nerve signaling chemical that controls movement and balance. Neurodegeneration occurs when a normal pro ...
Tissue Histology
Tissue Histology

... In general, the genes and receptors in MHC classes I and II are extremely important in recognizing self and in regulating the immune response. The MHC genes of humans are inherited from among a large pool of genes, so the cells of each person can exhibit variability in the pattern of cell surface mo ...
B cell activation and antibody production
B cell activation and antibody production

Specific Immunity - Truro School Moodle
Specific Immunity - Truro School Moodle

... Memory Cells • Live longer than plasma cells – often for decades. • They do not directly produce antibodies but circulate in the plama and tissue fluid. • When they encounter the same antigen later they can divide rapidly and clone to produce more plasma and memory cells. • Plasma cells then produc ...
Immunology Teacher Notes - Life Sciences Outreach Program
Immunology Teacher Notes - Life Sciences Outreach Program

... Broad Concept: All living things are composed of cells. Life processes in a cell are based on molecular interactions. ...
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... When recognition occurs, the B cell, with the help of Th cell cytokines, begins to secrete antibodies in soluble form The B cell also undergoes clonal expansion; repeated rounds of cell division The process includes mutations in the antibody genes of the daughter cells that leads to antibodies with ...
chapter 4 an introduction to cell structure and host
chapter 4 an introduction to cell structure and host

... • Microbial flora can protect us through microbial antagonism. – Many bacteria produce bacteriocins which are localized bacterial antibiotics. – Bacteriocins can kill invading organisms but do not affect the bacteria that produce them. Competition for space and other resources. ...
Immune Notes - The Lesson Locker
Immune Notes - The Lesson Locker

... Macrophages release chemicals which set the body’s thermostat at a higher temperature, resulting in a fever. b. The fever may increase phagocytosis, speed tissue repair, and inhibit bacterial growth. Natural killer (NK) cells do not attack microorganisms directly but destroy virus-infected body cell ...
Reconnaissance, Recognition, and Response
Reconnaissance, Recognition, and Response

... bring about apoptosis, or programmed cell death. To summarize the nonspecific defense systems, the first line of defense, the skin and mucous membranes, prevents most microbes from entering the body. The second line of defense uses phagocytes, natural killer cells, inflammation, and antimicrobial pr ...
emotions - Psychology
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... Elements of the Immune System Leukocytes (White blood cells) Most important elements Patrol the blood & fluids Antigens: Intruders have different surface proteins (nonself) than our own (self) WBCs attack antigens Macrophages and B Cells are specific defenses Antibodies search for specific antigens ...
Immunity - AState.edu
Immunity - AState.edu

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... produced in liver in response to inflammatory chemicals. ...
AQA Immunity Booklet Answers
AQA Immunity Booklet Answers

... develop into memory cells that enable a rapid response to future infections of the same pathogen stimulate b lymphocyte production (important in humoural immunity) kill infected cells by making a protein that causes lysis of the cell’s surface membrane. ...
Lymphatic System Part 2
Lymphatic System Part 2

...  T cells must recognize nonself and self (double recognition)  After antigen binding, clones form as with B cells, but different classes of cells are produced ...
Spectrum of Autoimmune Diseases
Spectrum of Autoimmune Diseases

- Journal of Allergy and Clinical Immunology
- Journal of Allergy and Clinical Immunology

... blanket that sweeps away inhaled or ingested particles. They also include soluble proteins and bioactive small molecules that are either constitutively present in biologic fluids (eg, the complement proteins1 and defensins2) or that are released from cells as they are activated (including cytokines ...
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Immune Troops! Move In! - Super Teacher Worksheets
Immune Troops! Move In! - Super Teacher Worksheets

... jobs is to gobble up and digest antigens. They are always swimming around in your blood stream, always on the lookout for antigens. And when they see one, GULP! Lymphocytes are also white blood cells and the main types are B cells, T helper cells, and T killer cells. Many antigens can be very sneaky ...
The immune system may be viewed as one aspect of the lymphatic
The immune system may be viewed as one aspect of the lymphatic

... large numbers of fully differentiated lymphocytes; these are the B cell and T cell types listed above. 3a. Cytotoxic T cells destroy virus infected host cells. (Some cells will be infected before the WBC are marshaled in defense.) 3b. Plasma cells secrete antibodies, which bind to the virus particle ...
TAT-mediated gp96 transduction to APCs enhances gp96
TAT-mediated gp96 transduction to APCs enhances gp96

...  Fusion of HBV-specific antigens to the N-terminal domain of gp96 gene could improve the potency of HBV DNA vaccines  PT-NT(gp96) DNA vaccine significantly decreased the percentage of regulatory CD4+ Tb cells. This effect could also contribute to further enhancement of PT-specific immune responses ...
SGOs - Pierce College
SGOs - Pierce College

... 12. What are seven compounds released during the inflammation process? What is the source and effect of each? 13. What processes during inflammation cause edema? 14. Which compounds cause edema during inflammation? 15. During inflammation, which compound triggers the rapid release of neutrophils? 16 ...
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... 0.5% of peripheral blood leukocytes. ...
Immune System – Part 2
Immune System – Part 2

... Antigen-binding site VARIES between each unique antibody The CONSTANT region defines Ab class and effector action ...
Chap 34 - Resistance of the Body to Infection
Chap 34 - Resistance of the Body to Infection

... 5. immune tolerance - limited ability of the immune system to attack a person's own body tissues V. Tolerance of the Acquired Immunity System A. self- tolerance = recognition of self B. develops in the preprocessing of T lymphocytes in the thymus and B lymphocytes in the ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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