Cindy Spangler
... rods, and helical, etc. shapes? What proteins build the cytoskeleton of prokaryotes and give them the different shapes? And how does this protein work? What were the results of the authors’ experiments and their conclusions? 1. Library of random trasposon (Tn5) insertion C. crescentus mutants were v ...
... rods, and helical, etc. shapes? What proteins build the cytoskeleton of prokaryotes and give them the different shapes? And how does this protein work? What were the results of the authors’ experiments and their conclusions? 1. Library of random trasposon (Tn5) insertion C. crescentus mutants were v ...
last year`s final exam
... 23) What is the function of snRNPs? 24) Mature, unfertilized eggs of many species have mRNAs for several genes but the proteins haven’t been made yet. What is preventing their synthesis? 25) What is the first amino acid to be added during synthesis of almost all eukaryotic proteins? 26) Describe one ...
... 23) What is the function of snRNPs? 24) Mature, unfertilized eggs of many species have mRNAs for several genes but the proteins haven’t been made yet. What is preventing their synthesis? 25) What is the first amino acid to be added during synthesis of almost all eukaryotic proteins? 26) Describe one ...
Slide 1
... AvrRpm1 or AvrB Induces RPM1-indepentdent Phosphorylation of RIN4, and RPM1 recognizes the phosphorylation to induce HR AvrRpt2 induces disappearance of RIN4, and RPS2 induce HR by the recognization of disappearance ...
... AvrRpm1 or AvrB Induces RPM1-indepentdent Phosphorylation of RIN4, and RPM1 recognizes the phosphorylation to induce HR AvrRpt2 induces disappearance of RIN4, and RPS2 induce HR by the recognization of disappearance ...
Transcription/Translation Instructions
... DNA makes RNA, RNA makes Proteins, and Proteins determine your Traits! 1) Collect either two yellow sheets or two blue sheets of DNA. 2) Connect page 2 to the bottom of page 1 to create one long strand of DNA (HINT: be careful not to cut off any base pairs!) 3) Fold the two combined sheets to cover ...
... DNA makes RNA, RNA makes Proteins, and Proteins determine your Traits! 1) Collect either two yellow sheets or two blue sheets of DNA. 2) Connect page 2 to the bottom of page 1 to create one long strand of DNA (HINT: be careful not to cut off any base pairs!) 3) Fold the two combined sheets to cover ...
Early Response Genes for G Protein Signaling in
... Project Name(s): Early Response Genes for G Protein Signaling in Mesenchymal Stem Cells General Topic (Keywords): stem cells; G proteins; adipogenesis; osteogenesis; RNAseq Project Description(s): Mesenchymal stem cells (MSCs) in the bone marrow serve as progenitors for multiple differentiated linea ...
... Project Name(s): Early Response Genes for G Protein Signaling in Mesenchymal Stem Cells General Topic (Keywords): stem cells; G proteins; adipogenesis; osteogenesis; RNAseq Project Description(s): Mesenchymal stem cells (MSCs) in the bone marrow serve as progenitors for multiple differentiated linea ...
Macromolecules
... Interactions: R-group interactions between each other and the environment Ex: nonpolar attractions, + and – attractions, hydrophilic interactions with ...
... Interactions: R-group interactions between each other and the environment Ex: nonpolar attractions, + and – attractions, hydrophilic interactions with ...
lecture notes endomembrane system 1
... Proteins are synthesized on ribosomes in the cytosol (a few are also made in mitochondria and chloroplasts). ...
... Proteins are synthesized on ribosomes in the cytosol (a few are also made in mitochondria and chloroplasts). ...
Lecture 12/13 - Intracellular Transport + Cytoskeleton
... 3.) What is the globular protein that forms microfilaments? Describe subunits of this protein. Describe polarity for this protein? 4.) What is treadmilling? 5.) What is myosin classified as? How does it perform its function? What reaction is involved? 6.) What are 3 different types of movement that ...
... 3.) What is the globular protein that forms microfilaments? Describe subunits of this protein. Describe polarity for this protein? 4.) What is treadmilling? 5.) What is myosin classified as? How does it perform its function? What reaction is involved? 6.) What are 3 different types of movement that ...
Section 5-4
... • The main function of genes is to control the production of proteins – A gene is a section of DNA – DNA is made of four nitrogen bases • Adenine (A) pairs with Thymine (T) • Guanine (G) pairs with Cytosine (C) ...
... • The main function of genes is to control the production of proteins – A gene is a section of DNA – DNA is made of four nitrogen bases • Adenine (A) pairs with Thymine (T) • Guanine (G) pairs with Cytosine (C) ...
A non-conventional nuclear import pathway Sandra Korge1, Bert
... Generating a 24 hour rhythm of the molecular circadian clock is influenced by transcriptional and translational regulation as well as post-translational processes as nucleocytoplasmic protein shuttling. As it is known for Period (PER), Cryptochrome (CRY) and other clock proteins to carry classical n ...
... Generating a 24 hour rhythm of the molecular circadian clock is influenced by transcriptional and translational regulation as well as post-translational processes as nucleocytoplasmic protein shuttling. As it is known for Period (PER), Cryptochrome (CRY) and other clock proteins to carry classical n ...
Structure I: DNA to RNA to Protein
... • Proteins are polymers of amino acids • Each protein has a unique sequence of amino acids • The sequence of amino acids specifies protein shape and function ...
... • Proteins are polymers of amino acids • Each protein has a unique sequence of amino acids • The sequence of amino acids specifies protein shape and function ...
Milk is a suspension of lipids and proteins. At... soluble because they have either a net positive or net...
... Milk is a suspension of lipids and proteins. At the pH of milk (about 6.4) these proteins are soluble because they have either a net positive or net negative charge. The charge keeps the proteins from interacting with each other by repelling each other yet and allows for sufficient solvation. The pr ...
... Milk is a suspension of lipids and proteins. At the pH of milk (about 6.4) these proteins are soluble because they have either a net positive or net negative charge. The charge keeps the proteins from interacting with each other by repelling each other yet and allows for sufficient solvation. The pr ...
Gene and Gene Regulation
... A section of DNA that synthesizes a protein that is needed for traits ...
... A section of DNA that synthesizes a protein that is needed for traits ...
Protein Structure and Folding
... ways N cysteins can pair with each other. Some proteins like many neutrophic factors contain odd number of cysteins. What kind of pair would you expect in this case? 2. Rearrange equation H - TS = RTln[D]/[N], where [D] is the concentration of the denatured and [N] the native protein, to [D]/([D]+ ...
... ways N cysteins can pair with each other. Some proteins like many neutrophic factors contain odd number of cysteins. What kind of pair would you expect in this case? 2. Rearrange equation H - TS = RTln[D]/[N], where [D] is the concentration of the denatured and [N] the native protein, to [D]/([D]+ ...
Slide 1 - Ommbid.com
... The left half of the figure represents the state of several proteins and mRNAs under normal conditions, the right half shows the activation of the UPR in response to an overload of the ER with unfolded or malfolded proteins. Under normal conditions the three effector proteins of the UPR (PERK, IRE1 ...
... The left half of the figure represents the state of several proteins and mRNAs under normal conditions, the right half shows the activation of the UPR in response to an overload of the ER with unfolded or malfolded proteins. Under normal conditions the three effector proteins of the UPR (PERK, IRE1 ...
ECS 189K - UC Davis
... http://www.rcsb.org, you can locate proteins by keyword searching or by entering the PDB accession number for the structure file, like 5PTI. Details on the molecule (how the structure was determined, pertinent research articles, position of secondary structures, unusual amino acids, etc) can be fou ...
... http://www.rcsb.org, you can locate proteins by keyword searching or by entering the PDB accession number for the structure file, like 5PTI. Details on the molecule (how the structure was determined, pertinent research articles, position of secondary structures, unusual amino acids, etc) can be fou ...
Zinc-finger proteins act as site-specific adapters for DNA
... "Our results demonstrate that zinc fingers are suitable site-selective adapters for targeting specific locations within DNA-origami structures," says Physiological processes and chemical reactions in Morii. "Several different adapters carrying different cells are highly specific and take place in se ...
... "Our results demonstrate that zinc fingers are suitable site-selective adapters for targeting specific locations within DNA-origami structures," says Physiological processes and chemical reactions in Morii. "Several different adapters carrying different cells are highly specific and take place in se ...
REGULATION OF GENE EXPRESSION
... a cluster of genes working together a region of the chromosome near the cluster: operator a region of the chromosome next to the operator: promotor products that initiates the production of enzymes are inducers ...
... a cluster of genes working together a region of the chromosome near the cluster: operator a region of the chromosome next to the operator: promotor products that initiates the production of enzymes are inducers ...
Exam Handout for PHAR2811 students, 2009
... characteristic of these cell lines. If telomerase wasn’t active then apoptosis would occur once there was a critical loss of genetic material and the cells would rapidly die off. 6. C. The Ames test relies on a mutant strain of Salmonella which is deficient in Histidine biosynthesis de novo. This st ...
... characteristic of these cell lines. If telomerase wasn’t active then apoptosis would occur once there was a critical loss of genetic material and the cells would rapidly die off. 6. C. The Ames test relies on a mutant strain of Salmonella which is deficient in Histidine biosynthesis de novo. This st ...
Biozentrum: Research group Martin Spiess
... Membrane proteins and their transport in the cell How are membrane proteins correctly assembled in the cell membrane and transported through the complex network of organelles in the cell? Errors in protein transport may result in disease. Membranes surround our cells and divide the cell interior int ...
... Membrane proteins and their transport in the cell How are membrane proteins correctly assembled in the cell membrane and transported through the complex network of organelles in the cell? Errors in protein transport may result in disease. Membranes surround our cells and divide the cell interior int ...
Proteins and The Cell Membrane
... membrane of the chloroplast. • Adenylate cyclase is an enzyme involved in ATP metabolism. Cholera bacteria release a toxin that interferes with the functioning of this enzyme resulting in Na+ and water leaving intestinal cells. Individuals may die from severe diarrhea. ...
... membrane of the chloroplast. • Adenylate cyclase is an enzyme involved in ATP metabolism. Cholera bacteria release a toxin that interferes with the functioning of this enzyme resulting in Na+ and water leaving intestinal cells. Individuals may die from severe diarrhea. ...
cell division. - cis myp science
... A centriole is a small set of microtubules arranged in a specific way. When two centrioles are found next to each other, they are usually at right angles. The centrioles are found in pairs and move towards the poles (opposite ends) of the nucleus when it is time for cell division. ...
... A centriole is a small set of microtubules arranged in a specific way. When two centrioles are found next to each other, they are usually at right angles. The centrioles are found in pairs and move towards the poles (opposite ends) of the nucleus when it is time for cell division. ...
Eukaryotic Gene Control
... • Example of how a duplication can lead to gene evolution: • α- globin and β- globin gene families • Shared a common ancestral globin gene • Duplicated and Diverged about 450- 500 million years ago • Divergence continues as duplications add up within the gene families • Other families have emerged f ...
... • Example of how a duplication can lead to gene evolution: • α- globin and β- globin gene families • Shared a common ancestral globin gene • Duplicated and Diverged about 450- 500 million years ago • Divergence continues as duplications add up within the gene families • Other families have emerged f ...
Lecture 11
... 3. The allosteric regulators bind to sites that are not active sites and elicit their effects by causing a Change in Shape of the Catalytic Subunit ...
... 3. The allosteric regulators bind to sites that are not active sites and elicit their effects by causing a Change in Shape of the Catalytic Subunit ...
A One- or Two-Day Course for Your Campus on
... Visual exploration of the 3D structures of macromolecules, such as proteins bound to ligands or nucleic acids. Where to find protein structures related to your research, how they are determined, how much of the genome is (and is not) known, and why. Teaching protein 3D structure, ligand interactions ...
... Visual exploration of the 3D structures of macromolecules, such as proteins bound to ligands or nucleic acids. Where to find protein structures related to your research, how they are determined, how much of the genome is (and is not) known, and why. Teaching protein 3D structure, ligand interactions ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.