![1.16891 / 1.16886 Fractogel® EMD COO](http://s1.studyres.com/store/data/014974931_1-636d159867134482eb79ceb5b6ccdc7b-300x300.png)
1.16891 / 1.16886 Fractogel® EMD COO
... to the tentacle technology. The Fractogel® beads have a high mechanical and chemical stability. Since the functional ion exchanger groups are bonded via linear polymer chains, the ionic groups are accessible for proteins. Fractogel® EMD COO- is a chromatographic support for the purification of basic ...
... to the tentacle technology. The Fractogel® beads have a high mechanical and chemical stability. Since the functional ion exchanger groups are bonded via linear polymer chains, the ionic groups are accessible for proteins. Fractogel® EMD COO- is a chromatographic support for the purification of basic ...
@ tin Scruppsfusrencu Iusrnurs
... According to Tainer, "Defectsin cell cycle control is a commontrait of all cancers. Understandingthe structureand function of this protein could be a first step in leading us to the developmentof more effective anti-cancertherapiesand/or an enhancementof those currently utilized." ...
... According to Tainer, "Defectsin cell cycle control is a commontrait of all cancers. Understandingthe structureand function of this protein could be a first step in leading us to the developmentof more effective anti-cancertherapiesand/or an enhancementof those currently utilized." ...
View attached file
... Daniel Segal - Research 'Conformational diseases' are diseases caused by misfolding of a protein, often as a result of a missense mutation that does not necessarily disrupt the active site of the protein. As a result, the protein may lose its function, and often the misfolded monomers self-assemble ...
... Daniel Segal - Research 'Conformational diseases' are diseases caused by misfolding of a protein, often as a result of a missense mutation that does not necessarily disrupt the active site of the protein. As a result, the protein may lose its function, and often the misfolded monomers self-assemble ...
6th semester-2006 Project Proposal
... neutral as possible regarding its folding and its biological activity. To achieve this, the tag should be of limited size, typically no more than 30 amino-acid residues. The basic assumption is that the smaller the tag, the lesser the probability that it interacts with the target protein. Of course, ...
... neutral as possible regarding its folding and its biological activity. To achieve this, the tag should be of limited size, typically no more than 30 amino-acid residues. The basic assumption is that the smaller the tag, the lesser the probability that it interacts with the target protein. Of course, ...
Proceedings of a meeting held at Allerton House, Monticello, Illinois
... these angles to better than a tenth of a radian, there would be 10300 possible configurations in our theoretical protein. In nature, proteins apparently do not sample all of these possible configurations since they fold in a few seconds, and even postulating a minimum time for going from one conform ...
... these angles to better than a tenth of a radian, there would be 10300 possible configurations in our theoretical protein. In nature, proteins apparently do not sample all of these possible configurations since they fold in a few seconds, and even postulating a minimum time for going from one conform ...
HonBio Chapter 3 notes
... Saturated – have the maximum number of hydrogens. Examples include beef fat and butter. Solid at room temperature. Trans fat – made by adding hydrogen to unsaturated fats. Associated with health risks. ...
... Saturated – have the maximum number of hydrogens. Examples include beef fat and butter. Solid at room temperature. Trans fat – made by adding hydrogen to unsaturated fats. Associated with health risks. ...
4.7.08 105 lecture
... transcription unit - the part of a gene that gets copied (transcribed) by RNA polymerase promoter – the genetic information in the DNA that tells where, when, and how much the gene should be expressed. ------------------------------coding region – For genes that make (encode) proteins, the codi ...
... transcription unit - the part of a gene that gets copied (transcribed) by RNA polymerase promoter – the genetic information in the DNA that tells where, when, and how much the gene should be expressed. ------------------------------coding region – For genes that make (encode) proteins, the codi ...
Chapter 2
... A mutation in a gene affects only the protein coded by the mutant copy of the gene and does not affect the protein coded by any other allele. Failure of two mutations to complement (produce wild phenotype when they are present in trans configuration in a heterozygote means that they are part of the ...
... A mutation in a gene affects only the protein coded by the mutant copy of the gene and does not affect the protein coded by any other allele. Failure of two mutations to complement (produce wild phenotype when they are present in trans configuration in a heterozygote means that they are part of the ...
Protein Folding File
... What are the two main structural motifs present in secondary folding of amino acid chains? What type of bonding stabilizes alpha helices and beta sheets? In addition to H-bonding, what type of bonding leads to stronger covalent bonds between amino acids? After secondary structures are formed, what i ...
... What are the two main structural motifs present in secondary folding of amino acid chains? What type of bonding stabilizes alpha helices and beta sheets? In addition to H-bonding, what type of bonding leads to stronger covalent bonds between amino acids? After secondary structures are formed, what i ...
Cell Building Blocks
... The secondary structure is formed by hydrogen bonds between amino acids. The polypeptide can coil into a helix or form a pleated sheet. The tertiary structure refers to the three-dimensional folding of the helix or pleated sheet. Quaternary The quaternary structure refers to the spatial relationship ...
... The secondary structure is formed by hydrogen bonds between amino acids. The polypeptide can coil into a helix or form a pleated sheet. The tertiary structure refers to the three-dimensional folding of the helix or pleated sheet. Quaternary The quaternary structure refers to the spatial relationship ...
presentation
... For assessing gene function (although not logically precise): as genes already known to be related do, in fact, tend to cluster together based on their experimentally determined expression patterns. The approach is made more systematic and statistically sound by calculating the probability that the ...
... For assessing gene function (although not logically precise): as genes already known to be related do, in fact, tend to cluster together based on their experimentally determined expression patterns. The approach is made more systematic and statistically sound by calculating the probability that the ...
the ubiquitin system and a putative stimulatory role
... It is not entirely accurate to think of Ub as a simple tag, as Ub does appear to be involved in degradation. The proteasome is the structure that actually does the degrading. Ubiquiton's degradation role may simply be to decrease the rate of dissociation between proteasomes and interacting substrate ...
... It is not entirely accurate to think of Ub as a simple tag, as Ub does appear to be involved in degradation. The proteasome is the structure that actually does the degrading. Ubiquiton's degradation role may simply be to decrease the rate of dissociation between proteasomes and interacting substrate ...
Lysis or Lysogeny? Gene Regulation by CI (and CI
... • Then I used the proteins similar to function and genes similar to function to find proteins in all phages (stored in biobike) that are similar to the CI repressor gene • Also used a list of genes that someone had created (subset) in my analysis ...
... • Then I used the proteins similar to function and genes similar to function to find proteins in all phages (stored in biobike) that are similar to the CI repressor gene • Also used a list of genes that someone had created (subset) in my analysis ...
Gene Expression
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
Gene Expression
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
Building proteins
... Specialized structures specialized functions cilia or flagella for locomotion Containers partition cell into compartments create different local environments separate pH, or concentration of materials distinct & incompatible functions lysosome & its digestive enzymes Membranes as sites for chemical ...
... Specialized structures specialized functions cilia or flagella for locomotion Containers partition cell into compartments create different local environments separate pH, or concentration of materials distinct & incompatible functions lysosome & its digestive enzymes Membranes as sites for chemical ...
Extend Your Understanding of the Bacterial
... bacterium. Transformation occurs in nature in certain types of bacteria and scientists have exploited and enhanced this property in the laboratory. Transformation allows scientists to move recombinant plasmids containing DNA from two or more species into bacterial cells to produce many copies of the ...
... bacterium. Transformation occurs in nature in certain types of bacteria and scientists have exploited and enhanced this property in the laboratory. Transformation allows scientists to move recombinant plasmids containing DNA from two or more species into bacterial cells to produce many copies of the ...
Abstract The cytoskeleton is a cellular structure comprised of three
... Abstract The cytoskeleton is a cellular structure comprised of three types of protein filaments called microfilaments, intermediate filaments and microtubules respectively. These filaments are highly dynamic and can change their organisation and properties according to the current needs of a cell. T ...
... Abstract The cytoskeleton is a cellular structure comprised of three types of protein filaments called microfilaments, intermediate filaments and microtubules respectively. These filaments are highly dynamic and can change their organisation and properties according to the current needs of a cell. T ...
Complete genomes comparison based on the taxonomic
... Examining the differences between protein sequences of various organisms gives insight into the origin of genes and the relationship between species. A new tool for the comparison of microbial genomes, called TaxPlot, provides a genome-wide approach to the study of gene and protein functions. TaxPlo ...
... Examining the differences between protein sequences of various organisms gives insight into the origin of genes and the relationship between species. A new tool for the comparison of microbial genomes, called TaxPlot, provides a genome-wide approach to the study of gene and protein functions. TaxPlo ...
Protein Synthesis PPT
... • Different proteins are made by combining these 20 amino acids in different combinations ...
... • Different proteins are made by combining these 20 amino acids in different combinations ...
Cartoon modeling of proteins
... formation + motor protein separation + control sequences) Self assembly of viruses from their coat proteins ...
... formation + motor protein separation + control sequences) Self assembly of viruses from their coat proteins ...
Cartoon modeling of proteins
... formation + motor protein separation + control sequences) Self assembly of viruses from their coat proteins ...
... formation + motor protein separation + control sequences) Self assembly of viruses from their coat proteins ...
ppt
... [protein] molecule are its complexity and its lack of symmetry. The arrangement seems to be almost totally lacking in the kind of regularities which one instinctively anticipates, and it is more complicated than has been predicted by any theory of protein structure.’ ...
... [protein] molecule are its complexity and its lack of symmetry. The arrangement seems to be almost totally lacking in the kind of regularities which one instinctively anticipates, and it is more complicated than has been predicted by any theory of protein structure.’ ...
Protein moonlighting
![](https://commons.wikimedia.org/wiki/Special:FilePath/3EL3.png?width=300)
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.