13059_2007_1664_MOESM13_ESM
... members (i.e. 'initial group membership' threshold in DAVID interface) . In order to control the quality of the seeding groups, the qualified seeding groups (qualified seeds) need to meet the second condition, i.e. majority (>50%) of members in the seed should have close relationships ...
... members (i.e. 'initial group membership' threshold in DAVID interface) . In order to control the quality of the seeding groups, the qualified seeding groups (qualified seeds) need to meet the second condition, i.e. majority (>50%) of members in the seed should have close relationships ...
Slide 1
... • Each of the three groups collects a portion of the total sequence data reported worldwide, and all new and updated database entries are exchanged between the groups on a daily basis ...
... • Each of the three groups collects a portion of the total sequence data reported worldwide, and all new and updated database entries are exchanged between the groups on a daily basis ...
Chapter 14 Proteins
... Integral membrane proteins form quaternary structures in which the outer surface is largely nonpolar (hydrophobic) and interacts with the lipid bilayer. Two of these are shown on the next screens. Figure 14.19 Integral membrane protein of rhodopsin, made of ahelices. ...
... Integral membrane proteins form quaternary structures in which the outer surface is largely nonpolar (hydrophobic) and interacts with the lipid bilayer. Two of these are shown on the next screens. Figure 14.19 Integral membrane protein of rhodopsin, made of ahelices. ...
1 CHAPTER 3- DNA FUNCTION – THE EXPRESSION OF GENETIC
... Transcription – production of RNA from a DNA template RNA polymerase – the enzyme which transcribes DNA into RNA Promoter – a set of DNA sequences to which RNA polymerase binds Repressor – a protein that binds to a DNA element and prevents transcription Activator – a protein that binds to a DNA elem ...
... Transcription – production of RNA from a DNA template RNA polymerase – the enzyme which transcribes DNA into RNA Promoter – a set of DNA sequences to which RNA polymerase binds Repressor – a protein that binds to a DNA element and prevents transcription Activator – a protein that binds to a DNA elem ...
Foreign Body Response
... (A) A space-filling model of myoglobin with hydrophobic amino acids shown in yellow, charged amino acids shown in blue, and others shown in white. The surface of the molecule has many charged amino acids, as well as some hydrophobic amino acids. (B) A cross-sectional view shows that mostly hydrophob ...
... (A) A space-filling model of myoglobin with hydrophobic amino acids shown in yellow, charged amino acids shown in blue, and others shown in white. The surface of the molecule has many charged amino acids, as well as some hydrophobic amino acids. (B) A cross-sectional view shows that mostly hydrophob ...
Fluorescent Protein Transformation Student Background
... by Bayer). Genes can be cut out of human, animal or plant DNA and placed inside bacteria. For example, a healthy human gene for the hormone insulin can be put into bacteria. Under the right conditions, these bacteria can make authentic human insulin just as they would make their own proteins. This i ...
... by Bayer). Genes can be cut out of human, animal or plant DNA and placed inside bacteria. For example, a healthy human gene for the hormone insulin can be put into bacteria. Under the right conditions, these bacteria can make authentic human insulin just as they would make their own proteins. This i ...
Lec 10 - Regulation of Gene
... Each cell of a living organism contains thousands of genes. But all genes do not function at a time. Genes function according to requirements of the cell. Genes control the phenotypic expression of various characters through the production of specific enzymes. Enzymes are special proteins which cata ...
... Each cell of a living organism contains thousands of genes. But all genes do not function at a time. Genes function according to requirements of the cell. Genes control the phenotypic expression of various characters through the production of specific enzymes. Enzymes are special proteins which cata ...
brochure - Your Bakery and Snack Solutions
... Nutritious PrOatein® is a natural protein concentrate from oats that can help you meet the fast growing consumer demand for protein-enriched foods. At Tate & Lyle Oat Ingredients in Sweden we extract the protein component of the oat bran using a patented process without the use of solvents – so that ...
... Nutritious PrOatein® is a natural protein concentrate from oats that can help you meet the fast growing consumer demand for protein-enriched foods. At Tate & Lyle Oat Ingredients in Sweden we extract the protein component of the oat bran using a patented process without the use of solvents – so that ...
Ribinik
... • Relatively large error may help to detect operons that have additional regulation. • Examples: 1. lacZ – very large error (150%) 2. uvrY – recently found to participate in another system and to be regulated by other transcription factors (45% error) ...
... • Relatively large error may help to detect operons that have additional regulation. • Examples: 1. lacZ – very large error (150%) 2. uvrY – recently found to participate in another system and to be regulated by other transcription factors (45% error) ...
Final Presentation
... GA was used to evolve the genome (configuration) used data for development. Affinity Based Model of Multicellular Development ...
... GA was used to evolve the genome (configuration) used data for development. Affinity Based Model of Multicellular Development ...
Pavel Doležal
... We purified and cloned two subunits of hydrogenosomal NADH dehydrogenase complex and showed that it can reduce a variety of electron carriers including ubiquinone, but unlike the mitochondrial enzyme it can also reduce ferredoxin. Phylogenetic analyses show that the T. vaginalis shares common ancest ...
... We purified and cloned two subunits of hydrogenosomal NADH dehydrogenase complex and showed that it can reduce a variety of electron carriers including ubiquinone, but unlike the mitochondrial enzyme it can also reduce ferredoxin. Phylogenetic analyses show that the T. vaginalis shares common ancest ...
ProtocolTargetDiscoveryVDS_Spring13
... In short, we want to find an enzyme that is crucial for the function or survival of a pathogenic organism. We need to have some confidence that the enzyme could be expressed and purified in the wet lab and we would like for the activity of the enzyme to be testable through spectrophotometric methods ...
... In short, we want to find an enzyme that is crucial for the function or survival of a pathogenic organism. We need to have some confidence that the enzyme could be expressed and purified in the wet lab and we would like for the activity of the enzyme to be testable through spectrophotometric methods ...
Pavel Doležal
... We purified and cloned two subunits of hydrogenosomal NADH dehydrogenase complex and showed that it can reduce a variety of electron carriers including ubiquinone, but unlike the mitochondrial enzyme it can also reduce ferredoxin. Phylogenetic analyses show that the T. vaginalis shares common ancest ...
... We purified and cloned two subunits of hydrogenosomal NADH dehydrogenase complex and showed that it can reduce a variety of electron carriers including ubiquinone, but unlike the mitochondrial enzyme it can also reduce ferredoxin. Phylogenetic analyses show that the T. vaginalis shares common ancest ...
Performance - Golden Glory Pharma Pte Ltd.
... since 1989. As 2010 marked our 21st year in the business, we relaunched PROLAB with an updated image that better targets our core consumer the "everyday athlete" with only the best selling items of the entire line. This relaunch comes dynamic new packaging and improved taste that helps the target co ...
... since 1989. As 2010 marked our 21st year in the business, we relaunched PROLAB with an updated image that better targets our core consumer the "everyday athlete" with only the best selling items of the entire line. This relaunch comes dynamic new packaging and improved taste that helps the target co ...
Novel recessive BFSP2 and PITX3 mutations: Insights into
... proteins (40 –70%), makes it tempting to speculate a dominant negative mechanism in which a PITX3 protein with reduced activation/transactivation capacity occupies the site of action of the normal counterpart.17 The novel PITX3 mutation we report here involves deletion of the same 17 bp that are dup ...
... proteins (40 –70%), makes it tempting to speculate a dominant negative mechanism in which a PITX3 protein with reduced activation/transactivation capacity occupies the site of action of the normal counterpart.17 The novel PITX3 mutation we report here involves deletion of the same 17 bp that are dup ...
Gene
... RP4 : : mini Mu plasmid pULB 113 was used. This plasmid is a derivative of the wide host-range conjugative plasmid RP4 and carries a deleted Mu prophage which allows the plasmid to pick up any chromosomal DNA segment to form R-prime plasmids (Van Gysegem and Toussaint, 1982). The plasmid renders cel ...
... RP4 : : mini Mu plasmid pULB 113 was used. This plasmid is a derivative of the wide host-range conjugative plasmid RP4 and carries a deleted Mu prophage which allows the plasmid to pick up any chromosomal DNA segment to form R-prime plasmids (Van Gysegem and Toussaint, 1982). The plasmid renders cel ...
Getting the message across: how do plant cells exchange
... Although Rab proteins are generally associated with the regulation of vesicle-mediated transport [22], they might also play a role in trafficking large ribonucleoprotein complexes to the cell periphery. For example, in the Drosophila oocyte, Rab11 has been shown to be involved in highly polarized mR ...
... Although Rab proteins are generally associated with the regulation of vesicle-mediated transport [22], they might also play a role in trafficking large ribonucleoprotein complexes to the cell periphery. For example, in the Drosophila oocyte, Rab11 has been shown to be involved in highly polarized mR ...
E. coli
... C-terminus of the light chain, additional site directed mutagenesis experiments with the plasmid encoding the single-chain Fv fragment were carried out. In the first approach, both ArgL114 and AlaL115 were changed to histidine residues and three additional histidine residues were added to the C-term ...
... C-terminus of the light chain, additional site directed mutagenesis experiments with the plasmid encoding the single-chain Fv fragment were carried out. In the first approach, both ArgL114 and AlaL115 were changed to histidine residues and three additional histidine residues were added to the C-term ...
CFTR: The Gene Associated with Cystic Fibrosis Official Gene
... Although there are no structures of the entire CFTR protein in the Protein Data Bank (PDB), an international archive of molecular structure data, a structure for a similar ABC transporter is available from the PDB. In September 2001, the journal Science published an article on the X-ray structure of ...
... Although there are no structures of the entire CFTR protein in the Protein Data Bank (PDB), an international archive of molecular structure data, a structure for a similar ABC transporter is available from the PDB. In September 2001, the journal Science published an article on the X-ray structure of ...
Detection and characterization of gamete‐specific molecules in
... The target of antibody G26-AG8 was found only in sperm (Fig. 2C). Based on the ultrastructural characterization of M. edulis sperm by Nijima and Dan (1965) the target of this mAb was found to be specific to the acrosome and appears to be located in a region termed as ‘partition bounding basal ring’. ...
... The target of antibody G26-AG8 was found only in sperm (Fig. 2C). Based on the ultrastructural characterization of M. edulis sperm by Nijima and Dan (1965) the target of this mAb was found to be specific to the acrosome and appears to be located in a region termed as ‘partition bounding basal ring’. ...
Bioinformatics Presentation
... transport of a gene product involved in one of these processes. As a result we don’t get any information in this search. ...
... transport of a gene product involved in one of these processes. As a result we don’t get any information in this search. ...
Anti-Parkin antibody ab15954 Product datasheet 23 Abreviews 3 Images
... cases (before 50 years) are known. The majority of the cases are sporadic suggesting a multifactorial etiology based on environmental and genetic factors. However, some patients present with a positive family history for the disease. Familial forms of the disease usually begin at earlier ages and ar ...
... cases (before 50 years) are known. The majority of the cases are sporadic suggesting a multifactorial etiology based on environmental and genetic factors. However, some patients present with a positive family history for the disease. Familial forms of the disease usually begin at earlier ages and ar ...
National Microbial Pathogen Database Resource (NMPDR): a
... complete. Genome data include the contig sequences, defined sequence features such as genes that encode RNAs or proteins, and annotations associated with each feature. Annotations include accurately determined boundaries of the features, and the assignment of a functional name to encoded proteins. N ...
... complete. Genome data include the contig sequences, defined sequence features such as genes that encode RNAs or proteins, and annotations associated with each feature. Annotations include accurately determined boundaries of the features, and the assignment of a functional name to encoded proteins. N ...
Full-Text PDF
... DCMECs from three biological replicates were provided by our laboratory. These cells were cultured according to the previous report [29]. DCMECs were grown in Dulbecco Modified Eagle Medium: Nutrient Mixture 12 (DMEM: F12) containing 10% fetal bovine serum (FBS), insulin (bovine, 5 μg mL−1), hydroco ...
... DCMECs from three biological replicates were provided by our laboratory. These cells were cultured according to the previous report [29]. DCMECs were grown in Dulbecco Modified Eagle Medium: Nutrient Mixture 12 (DMEM: F12) containing 10% fetal bovine serum (FBS), insulin (bovine, 5 μg mL−1), hydroco ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.