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Glycolysis
Glycolysis

... Glycolysis is a series of linked chemical reactions that convert glucose into pyruvic acid (pyruvate). A series of such reactions is called a biochemical “pathway.” It is fitting that we begin our study of biochemical pathways with glycolysis, since it was the first to be discovered. ...
Function and biotechnology of extremophilic enzymes in low water
Function and biotechnology of extremophilic enzymes in low water

What Is the Chemical Logic of the TCA Cycle?
What Is the Chemical Logic of the TCA Cycle?

Living on the edge: substrate competition explains loss of
Living on the edge: substrate competition explains loss of

... is involved in multifactorial and age-related diseases, such as obesity and type 2 diabetes [10]. The metabolism of a healthy individual is exceptionally robust with respect to perturbations in genetics, nutrition and workload, in the sense that key metabolic functions are normally unaffected by suc ...
The Mechanism of Propionic Acid Formation by
The Mechanism of Propionic Acid Formation by

... The method of formation of propionate from lactate and pyruvate by propionibacteria has remained uncertain. Werkman & Wood (1942) reviewed the various mechanisms suggested for the formation of propionic acid and made two proposals. The first was that water is removed from lactate to form acrylic aci ...
75. In yeast, if the electron transport system is shut down because of
75. In yeast, if the electron transport system is shut down because of

... b) two molecules of NADH. c) two molecules of pyruvic acid. d) two molecules of citric acid. e) two molecules of fructose. __ 27. The anaerobic breakdown of glucose is called: a) Fermentation b) Respiration c) Phosphorylation d) Chemosmosis e) Glycoysis __ 28. What results if glucose is metabolized ...
bile acids - The Vespiary
bile acids - The Vespiary

PSLDoc: Protein subcellular localization prediction based on
PSLDoc: Protein subcellular localization prediction based on

Document
Document

... Water has a high heat capacity. It can absorb or release a relatively large amount of heat with only a modest change in its own temperature. This property is due to the large number of hydrogen ions in water. Heat of vaporization is also high  amount of heat needed to change from liquid to gas  ev ...
David Rittenberg - National Academy of Sciences
David Rittenberg - National Academy of Sciences

PDF - FEMS Microbiology Letters
PDF - FEMS Microbiology Letters

... and, in an attempt to discover whether both compounds act as substrates for the same enzyme or whether a separate enzyme is involved, he concluded that it seems highly probable that only one enzyme is involved in both decarboxylations (Epps, 1944). Finally in 1948, McGilvery and Cohen, in the course ...
PDF - Oxford Academic
PDF - Oxford Academic

... DNA sequences in both genes corresponding to restriction enzyme cleavage sites were verified by cleavage with the appropriate restriction enzyme with one exception. In the Lbc gene a DNA sequence corresponding to a Clal cleavage site was determined at nucleotide positions 1024-1029. This sequence ha ...
Unnatural Amino Acid Mutagenesis of the GABAA Receptor Binding
Unnatural Amino Acid Mutagenesis of the GABAA Receptor Binding

... of the cation–␲ binding energy [determined as described by Mecozzi et al. (1996)], and the EC50 values compared with the parent molecule is shown in Figure 5; the direct relationship between these parameters shows there is a cation–␲ interaction here. In principle, the fluorination plot of Figure 5A ...
FREE Sample Here
FREE Sample Here

... 50) All cells have kept the same general patterns of metabolism, a very similar genetic code and the same monomers or residues. Answer: TRUE Page Ref: Section 1-5 51) Eukaryotes include plants, animals and bacteria. Answer: FALSE Page Ref: Section 1-5 52) The only reason phages are not considered to ...
Succinate Dehydrogenase of Saccharomyces cerevisiae
Succinate Dehydrogenase of Saccharomyces cerevisiae

Biochemistry - Text of NPTEL IIT Video Lectures
Biochemistry - Text of NPTEL IIT Video Lectures

... that we have gone through that is glycolysis for acetyl coenzyme A production. We have already seen the breakdown of glucose to pyruvate and we will see now how pyruvate actually gets to acetyl coenzyme A that then gets into the tricarboxylic acid cycle which eventually leads to the production of ca ...
Title Biotin Biosynthesis in Microorganisms (Commemoration Issue
Title Biotin Biosynthesis in Microorganisms (Commemoration Issue

... Since early studies of biotin biosynthesis, it has been recognized that DTB is converted to biotin during growth of various microorganisms.62-67> Using resting cells, biotin biosynthesis from DTB was demonstrated with some bacteria64,ss-79) and yeasts.71-74) There have been no studies on enzymic syn ...
Pathways of NeurSospora crassa and Saccharomyces cerevisiaet
Pathways of NeurSospora crassa and Saccharomyces cerevisiaet

... ate from glutamate in the acetylglutamate synthase reaction. Acetylglutamate is converted in several steps to acetylornithine, followed by transfer of the acetyl group to another molecule of glutamate. This regenerates acetylglutamate as ornithine is formed (Fig. 1). Thus most glutamate enters the p ...
A defined subset of adenylyl cyclases is regulated by bicarbonate ion.
A defined subset of adenylyl cyclases is regulated by bicarbonate ion.

Studier`s autoinduction media
Studier`s autoinduction media

... fresh overnight culture grown in PA-0.5G. Growth at 37C from a thousand-fold dilution into PASM5052 typically reaches saturation in 14-16 hours. Growth at 20C is much slower and a culture can take 3 days or longer to become induced and reach saturation. Although still testing, we expect that the c ...
pyruvate dehydrogenase complex
pyruvate dehydrogenase complex

... This is an e.g. of substrate-level phospho. • Succinate is oxidized to fumarate by succinate dehydrogenase, producing FADH2. this enz is inhibited by OAA. • Fumarate is hydrated to malate by fumarase (= fumarate hydratase), and malate is oxidized to OAA by malate dehydrogenase, producing NADH. • Thr ...
Geochemical Journal
Geochemical Journal

... acids) in carbonates and muddy sediments obeyed firstorder kinetics at 180 and 220°C, and that the rate at 220°C was three-fold greater than that at 180°C. Qian et al. (1993) showed that the decomposition rates of glycine, alanine, and glutamic acid obeyed first-order kinetics in aqueous solutions ...
Mechanism of action of exo-acting α-1,4-glucan lyase
Mechanism of action of exo-acting α-1,4-glucan lyase

... Abstract: α-1,4-Glucan lyase (GLase) performs a β-elimination reaction on α-1,4-glucans. However, GLase is different in many aspects from the polysaccharide lyase that also performs a β-elimination reaction on uronic acid containing sugars. While polysaccharide lyase mechanistically takes an anionic ...
Requires Rubisco
Requires Rubisco

... At 5 x 10 -5 atm, CO2 fixation rate = photorespiration rate. However, plants living in hot climates need to conserve water, which requires them to use low CO2 concentration (water is used in rubisco reaction!) The disadvantage of C4 plants is extra ATP used and a more complex pathway http://methanog ...
Plant aromatic amino acid decarboxylases
Plant aromatic amino acid decarboxylases

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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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