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metabolic factors in fatigue
... the continual regeneration of ATP is critical for the maintenance of muscle force output during sustained exercise performance. At high power outputs (such as those observed during high-intensity sprint exercise), this is achieved through non-oxidative (anaerobic) ATP production following the breakd ...
... the continual regeneration of ATP is critical for the maintenance of muscle force output during sustained exercise performance. At high power outputs (such as those observed during high-intensity sprint exercise), this is achieved through non-oxidative (anaerobic) ATP production following the breakd ...
The Language of Life
... randomness in assignment of amino acids to codons No mechanism exists for genetic code evolution Thus variation in the genetic code suggests a polyphyletic origin for life Taken together, this evidence indicates the hand of a Designer in the genetic code and does not support the theory that life ori ...
... randomness in assignment of amino acids to codons No mechanism exists for genetic code evolution Thus variation in the genetic code suggests a polyphyletic origin for life Taken together, this evidence indicates the hand of a Designer in the genetic code and does not support the theory that life ori ...
GLUCOKINASE ACTIVATORS: A GLUCOSE SENSOR ROLE IN PANCREATIC ISLETS AND HEPATOCYTE
... Amino acids to be involved in GKA binding: V62, R63, S64, T65, G68, S69, G72, V91, W99, M210, I211,Y214, Y215, M235, V452,V455, and K459[15]. Most GKAs do not bind to GK in the absence of glucose. GKAs potentiate the competitive glucose reversal of GK inhibition by Glucokinase regulating protein (GK ...
... Amino acids to be involved in GKA binding: V62, R63, S64, T65, G68, S69, G72, V91, W99, M210, I211,Y214, Y215, M235, V452,V455, and K459[15]. Most GKAs do not bind to GK in the absence of glucose. GKAs potentiate the competitive glucose reversal of GK inhibition by Glucokinase regulating protein (GK ...
Catalase - Alpha Diagnostic International
... Catalase is a common enzyme found in nearly all living organisms that are exposed to oxygen, where it functions to catalyze the decomposition of hydrogen peroxide to water and oxygen. Catalase has one of the highest turnover numbers of all enzymes; one molecule of catalase can convert 40 million mol ...
... Catalase is a common enzyme found in nearly all living organisms that are exposed to oxygen, where it functions to catalyze the decomposition of hydrogen peroxide to water and oxygen. Catalase has one of the highest turnover numbers of all enzymes; one molecule of catalase can convert 40 million mol ...
12 Molecular Visualization of an Enzyme, Acetylcholinesterase
... Figure 12.1: A schematic of the acetylcholinesterase active site showing the electron movement during the initial nucleophilic attack of acetylcholine: The alcohol acts as a nucleophile attacking the ester carbonyl carbon. This alcohol is a strong nucleophile because the adjacent imidazole ring chan ...
... Figure 12.1: A schematic of the acetylcholinesterase active site showing the electron movement during the initial nucleophilic attack of acetylcholine: The alcohol acts as a nucleophile attacking the ester carbonyl carbon. This alcohol is a strong nucleophile because the adjacent imidazole ring chan ...
Journal of Agricultural and Food Chemistry
... species, respectively. All species and cultivars can be distinguished from each other. Soybean, quinoa, and buckwheat species had a characteristic protein pattern showing a high degree of polymorphism. The protein patterns of soybean were considerably different from other species. Amaranth species h ...
... species, respectively. All species and cultivars can be distinguished from each other. Soybean, quinoa, and buckwheat species had a characteristic protein pattern showing a high degree of polymorphism. The protein patterns of soybean were considerably different from other species. Amaranth species h ...
Nordonia Hills City Schools Honors Chemistry Course of Study
... subatomic particles. Compare and contrast contributors to early atomic theory: Greeks, Dalton, Thomson, Rutherford, Chadwick, and Bohr) Describe concepts involved in Dalton's postulates (i.e. constant composition) as well as shortcomings of same postulates. Perform different experiments using indire ...
... subatomic particles. Compare and contrast contributors to early atomic theory: Greeks, Dalton, Thomson, Rutherford, Chadwick, and Bohr) Describe concepts involved in Dalton's postulates (i.e. constant composition) as well as shortcomings of same postulates. Perform different experiments using indire ...
Fritz Lipmann - Nobel Lecture
... rather specifically coupled with the glycolytic reaction. Here, however, we had found a coupling of phosphorylation with a respiratory system. This observation immediately suggested a rather sweeping biochemical significance, of transformations of electron transfer potential, respiratory or fermenta ...
... rather specifically coupled with the glycolytic reaction. Here, however, we had found a coupling of phosphorylation with a respiratory system. This observation immediately suggested a rather sweeping biochemical significance, of transformations of electron transfer potential, respiratory or fermenta ...
mbe.oxfordjournals.org - Oxford Academic
... Research on the biogenesis of ribosomal subunits concentrating on rRNA transcription, processing, and maturation has neglected the influence of ribosomal proteins in the assembly process. However, in 2005, Milkereit’s group (Ferreira-Cerca et al. 2005) demonstrated that eukaryotic ribosomal proteins ...
... Research on the biogenesis of ribosomal subunits concentrating on rRNA transcription, processing, and maturation has neglected the influence of ribosomal proteins in the assembly process. However, in 2005, Milkereit’s group (Ferreira-Cerca et al. 2005) demonstrated that eukaryotic ribosomal proteins ...
51`oUL cUoa
... activity is hindered by Zn2+, Bc2+, PO43", ASO43", CN~, oxalate, citrate ions, and thiol compounds. Both groups have a fairly broad substrate specificity, thus they are capable of hydrolyzing a variety of physiological and nonphysiological substrates, like glycerol phosphate and p-nitrophenyl phosph ...
... activity is hindered by Zn2+, Bc2+, PO43", ASO43", CN~, oxalate, citrate ions, and thiol compounds. Both groups have a fairly broad substrate specificity, thus they are capable of hydrolyzing a variety of physiological and nonphysiological substrates, like glycerol phosphate and p-nitrophenyl phosph ...
The complete nucleotide sequence of the RNA coding for the
... residue (2, 3 i The VPg protein is not required for translation and, by correlation with poliovirus is probably involved in replication (A, 5). The RNA of FMDV, like other picornaviruses, appears to have a long 5' untranslated leader sequence. Removal of the poly C tract of FMDV and all nucleotides ...
... residue (2, 3 i The VPg protein is not required for translation and, by correlation with poliovirus is probably involved in replication (A, 5). The RNA of FMDV, like other picornaviruses, appears to have a long 5' untranslated leader sequence. Removal of the poly C tract of FMDV and all nucleotides ...
Structure and biosynthesis of the signal
... The SSR is present in the ER membrane of various types of cells of different species in excess over membrane-bound ribosomes [lo], in keeping with its assumed role as a constituent of the translocation complex. The protein appears to be essential for translocation since antibodies directed against i ...
... The SSR is present in the ER membrane of various types of cells of different species in excess over membrane-bound ribosomes [lo], in keeping with its assumed role as a constituent of the translocation complex. The protein appears to be essential for translocation since antibodies directed against i ...
Creation/Evolution
... randomness in assignment of amino acids to codons No mechanism exists for genetic code evolution Thus variation in the genetic code suggests a polyphyletic origin for life Taken together, this evidence indicates the hand of a Designer in the genetic code and does not support the theory that life ori ...
... randomness in assignment of amino acids to codons No mechanism exists for genetic code evolution Thus variation in the genetic code suggests a polyphyletic origin for life Taken together, this evidence indicates the hand of a Designer in the genetic code and does not support the theory that life ori ...
Kinesin Microtubule Gliding Assay 1. Make labeled microtubules
... 1) If you have a very slow moving motor it can be useful to flow in just MTs diluted in BCB and allow them to bind (turn coverslip face down and wait a few minutes). Then flow in motility mix containing everything except MTs. This will reduce the background fluorescence and prevent extra MTs binding ...
... 1) If you have a very slow moving motor it can be useful to flow in just MTs diluted in BCB and allow them to bind (turn coverslip face down and wait a few minutes). Then flow in motility mix containing everything except MTs. This will reduce the background fluorescence and prevent extra MTs binding ...
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
... method (23) allows the separation of charged from uncharged tRNA due to a difference in electrophoretic mobility between the two species. Hybridization of a sequence-specific probe permits the determination of the identity of the tRNA on the gel. Unfractionated tRNA (80 g) from H. pylori or A. ferr ...
... method (23) allows the separation of charged from uncharged tRNA due to a difference in electrophoretic mobility between the two species. Hybridization of a sequence-specific probe permits the determination of the identity of the tRNA on the gel. Unfractionated tRNA (80 g) from H. pylori or A. ferr ...
catalogue 2012 - olimp
... Each supplier is subject to a strict selection procedure. Already at the very beginning we are made to reject approximately 50% of candidates. It is not easy to become a supplier of Olimp! Each batch of materials undergoes a strict testing procedure; even if the results of pilot trials are positive ...
... Each supplier is subject to a strict selection procedure. Already at the very beginning we are made to reject approximately 50% of candidates. It is not easy to become a supplier of Olimp! Each batch of materials undergoes a strict testing procedure; even if the results of pilot trials are positive ...
Compound specific amino acid δ13C patterns in a deep
... evolving analytical tool that can resolve much of the uncertainty in bulk isotopic data. δ15N CSI-AA has now been measured in many different types of organisms in order to analyze trophic dynamics and decouple baseline δ15N values from food web effects (e.g., McClelland and Montoya, 2002; McClelland ...
... evolving analytical tool that can resolve much of the uncertainty in bulk isotopic data. δ15N CSI-AA has now been measured in many different types of organisms in order to analyze trophic dynamics and decouple baseline δ15N values from food web effects (e.g., McClelland and Montoya, 2002; McClelland ...
ANTIBIOTICS
... In 1928, Fleming noted that a bacterial culture which had been left several weeks open to the air had become infected by a fungal colony. Of more interest was the fact that there was an area surrounding the fungal colony where the bacterial colonies were dying. He correctly concluded that the fungal ...
... In 1928, Fleming noted that a bacterial culture which had been left several weeks open to the air had become infected by a fungal colony. Of more interest was the fact that there was an area surrounding the fungal colony where the bacterial colonies were dying. He correctly concluded that the fungal ...
Structural and Biochemical Characterization of a Bifunctional
... ABSTRACT: Unusual N-acetylated sugars have been observed on the O-antigens of some Gram-negative bacteria and on the S-layers of both Gram-positive and Gram-negative bacteria. One such sugar is 3-acetamido-3,6-dideoxy-α-D-galactose or Fuc3NAc. The pathway for its production requires five enzymes with ...
... ABSTRACT: Unusual N-acetylated sugars have been observed on the O-antigens of some Gram-negative bacteria and on the S-layers of both Gram-positive and Gram-negative bacteria. One such sugar is 3-acetamido-3,6-dideoxy-α-D-galactose or Fuc3NAc. The pathway for its production requires five enzymes with ...
Valproate
... No therapeutic range is quoted for Valproate (Pathology Harmony 2011) as serum/plasma concentrations do not correlate well with anticonvulsant activity. However, toxic effects are commonly observed at levels > 100 mg/L. ...
... No therapeutic range is quoted for Valproate (Pathology Harmony 2011) as serum/plasma concentrations do not correlate well with anticonvulsant activity. However, toxic effects are commonly observed at levels > 100 mg/L. ...
Metabolism
![](https://commons.wikimedia.org/wiki/Special:FilePath/ATP-3D-vdW.png?width=300)
Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.