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misinformation, misrepresentation, and misuse of human behavioral
misinformation, misrepresentation, and misuse of human behavioral

... more prone to violent behavior are also more likely to have certain genes, or if people who tend to score highly on standardized intelligence tests also share particular genetic traits. On the other hand, researchers interested in behaviors that do not vary significantly within a population have oth ...
Submitting an RNA-Seq job at PATRIC
Submitting an RNA-Seq job at PATRIC

... sites with direct mapping to known transcripts, producing sensitive and accurate alignments, even for highly repetitive genomes or in the presence of pseudogenes. HISAT (hierarchical indexing for spliced alignment of transcripts)[3] is a highly efficient system for aligning reads from RNA sequenc ...
the art and design of genetic screens
the art and design of genetic screens

... Geneticists use both forward and reverse selections. A forward selection allows the growth of mutants in which a particular gene function is lost. For example, the selection used by Luria and Delbruck3 for resistance to phage T1 is a forward selection that allows the growth of bacteria that have los ...
PersPecTIves - Ralf Sommer
PersPecTIves - Ralf Sommer

... ventral patterning genes have shown striking differences between T. castaneum and D. melanogaster in the function of individual genes and of genetic networks (BOX 2). In particular, gene duplications and subfunctionalization are crucial for extra-embryonic membrane formation and dorso–ventral patter ...
Concordance trees, concordance factors, and the exploration of
Concordance trees, concordance factors, and the exploration of

... has a known population history. At best one has molecular data for a number of loci for a set of individuals representative of the taxa under study. If we are prepared to make some assumptions about the nature of populations and genetic processes, these data contain information on the history of the ...
Application title: Cloning genes for expression in AAV vectors for
Application title: Cloning genes for expression in AAV vectors for

... human cells as well as cells and whole animals of the following: mouse, rat, rabbit, cattle, goat and sheep. The recombinant proteins we want to research are for the prevention, diagnosis and treatment of the following: endocrine, nutritional and metabolic diseases, infectious and parasitic diseases ...
Chapter 4 - DORAS
Chapter 4 - DORAS

... of M63 minimal media (section 2.2). These M63 cultures were then incubated at 37oC overnight and used to seed the M63 bioassays. To prepare the bioassays, M63 agar (25 ml) supplemented with 100 μM of the iron chelator 2,2′-dipyridyl, the appropriate antibiotics and 1 mM IPTG was solidified in a Petr ...
Mapping the Genetic Architecture of Gene Expression in Human Liver
Mapping the Genetic Architecture of Gene Expression in Human Liver

... analysis provide a significantly reduced set of SNPs on which to focus (;3,700 versus 782,476). The set of SNPs associated with expression (eSNPs) can be considered a functionally validated set, given that the SNPs in this set have been found to associate with biologically relevant control of gene ex ...
The Frequency Distribution of Nucleotide Variation in Drosophila
The Frequency Distribution of Nucleotide Variation in Drosophila

... from one analysis to another (e.g., between this report and Begun and Whitley [2000b]), because some codons with more than one mutation can be used in certain analyses, but not in others. The criteria of Sharp and Lloyd (1993) were used to assign codons to putative fitness classes, preferred ...
Solid Tumour Section Nervous system: Medulloblastoma Atlas of Genetics and Cytogenetics
Solid Tumour Section Nervous system: Medulloblastoma Atlas of Genetics and Cytogenetics

... © 2000 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
Specific Combinations of Zein Genes and Genetic Backgrounds
Specific Combinations of Zein Genes and Genetic Backgrounds

... As in O2 lines, in the o2 genotypes the pattern that occurs at maturity is almost identical to the one present in immature seeds at 20 or 25 days after pollination (DAP; Fig. 1B). In any case the zein pattern observed for each line is constant in seeds obtained from field- or greenhouse-grown plants ...
The Science of Psychology
The Science of Psychology

... changes that occur in people as they age from conception until death. • Longitudinal design - research design in which one participant or group of participants is studied over a long period of time. • Cross-sectional design - research design in which several different age groups of participants are ...
Gene density and transcription influence the localization of
Gene density and transcription influence the localization of

... localization outside of chromosome territories is not a common feature of imprinted regions. Localization outside of a chromosome territory is common to gene-rich regions of the human genome The relative intraterritory position of loci from 15q12 was intermediate to that of 11p13 (Mahy et al., 2002) ...
Temperature-dependent expression of virulence genes in fish
Temperature-dependent expression of virulence genes in fish

... The paradigms of this adaptation are the cold and heat shock response systems under which the bacteria induce a fast response to sudden and extreme temperature shift (Guisbert et al., 2008; Shamovsky and Nudler, 2008; Barria et al., 2013). In any case, temperature variations involve remodeling gene ...
XASH genes promote neurogenesis in Xenopus embryos
XASH genes promote neurogenesis in Xenopus embryos

... MCK/CAT reporter gene in transfected 10T1/2 cells (Zimmerman et al., 1993), it is perhaps surprising that XASH3 activates neural gene expression but not muscle gene expression in vivo. This suggests that XASH-3 is not a promiscuous in vivo, and that it may show this particular specificity in the con ...
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)

... Upon detailed bacteriological investigation, 56(77.78%) isolates were tentatively identified as motile A. sobria which can be differentiate from other Aeromonas sp. as it can produce gas from glucose but does not hydrolyze esculin [12], whereas, other Aeromonas sp. produce gas from glucose and hydro ...
Allele Mining Strategies: Principles and Utilisation for Blast
Allele Mining Strategies: Principles and Utilisation for Blast

... regions of the genome. Mutations may take the form of insertions or deletions, which might be together called InDels, or may alter a single nucleotide inside the genome sequence, resulting in a single-nucleotide polymorphism (SNP). The mutations in coding regions could have an excellent effect on th ...
The evolution of photosynthesis and chloroplasts
The evolution of photosynthesis and chloroplasts

... uses two photosystems: photosystem II (PSII; lightinduced water plastoquinone oxidoreductase3) and photosystem I (PSI)19. There must be an OEC attached to the type 2 photosystem to make it a true PS II. The two photosystems must be connected in series to generate sufficient difference in redox poten ...
not a plastid specific promoter but is also capable of
not a plastid specific promoter but is also capable of

... and appears to occur at both transcriptional and posttranscriptional level (3). Recently, the sequence analysis of two entire plastid genomes, Nicotiana tabacum and Marchantia polymorpha, has been completed (4, 5). To identify plastid sequences important for gene regulation at DNA and/or RNA level, ...
Genetics of Male Infertility - the Infertility Center of St. Louis
Genetics of Male Infertility - the Infertility Center of St. Louis

... accurately placed in what was then called deletion intervals 6D-6F. Even the size of AZFc (without an accurate sequence) was controversial (0.5 to 2 Mb) (62,105-106). Efforts to find point mutations along the Y chromosome, have also been thwarted by the presence of multiple copies of genes in these ...
Meiosis Notes
Meiosis Notes

... The linkage groups assorted independently, but all of the genes in one group were inherited together. As it turns out, Drosophila has four linkage groups and four pairs of chromosomes. ...
Research Update Winter 2003/2004
Research Update Winter 2003/2004

... Learning about this variation is an causes the features of Down syndrome. exciting prospect and a priority of The Medical researchers around the world, National Down Syndrome Project. It is including those of us with the National likely to take some Down Syndrome time. First we need Project, are now ...
Transposable elements in Escherichia coli antimicrobial resistance
Transposable elements in Escherichia coli antimicrobial resistance

... by transposons bestows upon the bacteria a fitness impact enabling it to survive better under selection pressure. E. coli is known to have acquired resistance to chloramphenicol, tetracycline and kanamycin from genes carried on transposons [36]. Therefore, as is evidenced by the above reports, start ...
Relationship between expression and methylation of obesity
Relationship between expression and methylation of obesity

... colour-barcodes allows for the generation of direct counts of RNA transcript, which is a more readily interpretable data format than the fluorescence values or cycle thresholds (Ct) that are obtained from other expression methodologies. Lastly, nCounter does not rely on a PCR amplification step, mea ...
Engineered bacteriophage-defence systems in bioprocessing
Engineered bacteriophage-defence systems in bioprocessing

... question exhibit distinct phagesensitivity profiles, meaning that they are attacked by different groups of phages. ...
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Minimal genome

The concept of minimal genome assumes that genomes can be reduced to a bare minimum, given that they contain many non-essential genes of limited or situational importance to the organism. Therefore, if a collection of all the essential genes were put together, a minimum genome could be created artificially in a stable environment. By adding more genes, the creation of an organism of desired properties is possible. The concept of minimal genome arose from the observations that many genes do not appear to be necessary for survival. In order to create a new organism a scientist must determine the minimal set of genes required for metabolism and replication. This can be achieved by experimental and computational analysis of the biochemical pathways needed to carry out basic metabolism and reproduction. A good model for a minimal genome is Mycoplasma genitalium, the organism with the smallest known genome. Most genes that are used by this organism are usually considered essential for survival; based on this concept a minimal set of 256 genes has been proposed.
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